- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Charleston, SC to Indianapolis, IN
Showing times and prices for Aug 05
Cheapest price
$115
Average price
$116
Fastest journey
23 h 20 m
Average duration
1 d 3 h 33 m
Buses per day
2
Distance
957 km
Cheap tickets
The best way to find a cheap bus ticket from Charleston, SC to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, SC to Indianapolis, IN will cost around $116 if you buy it on the day, but the cheapest tickets can be found for only $115.
Fast buses
It's difficult to get from Charleston, SC to Indianapolis, IN without transferring at least 2 times.
+
FlixBus+12:50 PM23h20Charleston, Gaynor Avenue (Greyhound Bus Station), SC12:10 PMIndianapolis, Illinois St (Greyhound Bus Station)$1151One-way2 transfers- FlixBus+ · 2:00 PM31h45Charleston, Gaynor Avenue (Greyhound Bus Station), SC9:45 PMIndianapolis, E Washington St / N Delaware St (City/County Building), IN$1181One-way2 transfers
- +FlixBus+12:50 PM23h20Charleston, Gaynor Avenue (Greyhound Bus Station), SC12:10 PMIndianapolis, Illinois St (Greyhound Bus Station)$1151One-way2 transfers
- FlixBus+ · 2:00 PM31h45Charleston, Gaynor Avenue (Greyhound Bus Station), SC9:45 PMIndianapolis, E Washington St / N Delaware St (City/County Building), IN$1181One-way2 transfers
Journey information
Overview: Bus from Charleston, SC to Indianapolis, IN
USAUSA
Buses from Charleston, SC to Indianapolis, IN run on average 2 times per day, taking around 23h 25m. Cheap bus tickets for this journey start at $113 but you can travel from only $46 by flight.
The earliest bus runs at 00:15, the last at 23:30. The fastest bus covers the 594 miles (957 km) distance in 24h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $46
Distance 594 miles (957 km) |
Average bus duration 23h 25m |
Cheapest ticket price $113 |
Buses per day 2 |
Fastest bus 24h 50m |
First bus 12:15 AM |
Last bus 11:30 PM |
Cheapest Month Nov |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $46
Charleston, SC to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 11:15AM | Arrival Time 12:10PM | Duration 24h55 | Departure days Tue | Cheapest price $119 |
Operator Greyhound | Departure Time 12:50PM | Arrival Time 12:10PM | Duration 23h20 | Departure days Everyday | Cheapest price $98 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 09:45PM | Duration 31h45 | Departure days Everyday | Cheapest price $97 |
Live departures
Charleston, SC to Indianapolis, IN bus times
The table below shows live departures for Charleston, SC to Indianapolis, IN buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 11:15 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 24h55 | 12:10 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| +FlixBus+ · | 12:50 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 29h40 | 6:30 PM Indianapolis, Illinois St (Greyhound Bus Station) | 3 transfers | |
| · +FlixBus | 2:00 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 31h45 | 9:45 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Charleston, SC to Indianapolis, IN buses with Omio?
Greyhound as well as CARTA offer buses services from Charleston, SC to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from Charleston, SC to Indianapolis, IN.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of CARTA to find the best option for your trip from Charleston, SC to Indianapolis, IN.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Charleston, SC to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Charleston, SC to Indianapolis, IN.
Bus providers: Greyhound, CARTA from Charleston, SC to Indianapolis, INYou can travel by bus between Charleston, SC to Indianapolis, IN with Greyhound, CARTA for as low as $46. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
24h 50m
Cheapest Price
$113
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
CARTA
Luggage & cancellation policy
Average Duration
35h 20m
CARTA frequency
1 a day
Complete guide to Indianapolis, IN
Things to do in Indianapolis, IN
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
- Must visit
Indianapolis Museum of Art at Newfields
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
- Recommended
Benjamin Harrison Presidential Site
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
- Must visit
Central Canal
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
- Must visit
Monument Circle
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
- Must visit
Indianapolis Cultural Trail
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Pork Tenderloin Sandwich
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
- Vegetarian
Sugar Cream Pie
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
- Gluten-free
St. Elmo-Style Shrimp Cocktail
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Vida
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
St. Elmo Steak House
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Harry & Izzy's
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
United States Dollar ($)
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Average meal costs
- Budget
- $10-$18 for fast food or a casual meal.
- Mid-range
- $20-$40 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-$6 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
FAQs: Bus from Charleston, SC to Indianapolis, IN
Find answers to the most common questions about traveling from Charleston, SC to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Charleston, SC to Indianapolis, IN can start from as little as $113 when you book in advance. The average bus ticket price for Charleston, SC to Indianapolis, IN is $172 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Charleston, SC to Indianapolis, IN is 24h 50m to travel the 594 miles (957 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Charleston, SC to Indianapolis, IN leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Charleston, SC to Indianapolis, IN leaves at 11:30 PM.
There are 2 buses a day from Charleston, SC to Indianapolis, IN which require at least one change with Greyhound, CARTA. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Charleston, SC to Indianapolis, IN, you can count on Greyhound, CARTA for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between Charleston, SC and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 3 ways to travel between Charleston, SC and Indianapolis, IN including taking a bus, flight, and train.
Yes, the following accessibility options are available when taking the bus from Charleston, SC to Indianapolis, IN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Charleston, SC to Indianapolis, IN for bus company Greyhound.
Whether you can cancel your bus ticket from Charleston, SC to Indianapolis, IN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Charleston, SC to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from Charleston, SC to Indianapolis, IN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Charleston, SC to Indianapolis, IN:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Charleston, SC to Indianapolis, IN.
You can reserve your seat on the bus from Charleston, SC to Indianapolis, IN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Charleston, SC to Indianapolis, IN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Charleston, SC to Indianapolis, IN with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Charleston, SC to Indianapolis, IN
Most Charleston, SC to Indianapolis, IN buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Indianapolis, Illinois St (Greyhound Bus Station) station pair, with some services arriving at Indianapolis, E Washington St / N Delaware St (City/County Building). Use this guide to compare Charleston, SC and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Charleston
Arrival bus stations in Indianapolis
Charleston, Gaynor Avenue (Greyhound Bus Station)
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Indianapolis, Illinois St (Greyhound Bus Station)
Indianapolis, E Washington St / N Delaware St (City/County Building)
Most popular bus connections from Charleston, SC
More options for your journey from Charleston, SC to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular buses to and from Indianapolis, IN and Charleston, SC
Most popular bus connections to Indianapolis, IN
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
