- Must visit
Newfields
Major campus combining the Indianapolis Museum of Art, gardens, and seasonal installations. Strong all-around choice for art, design, and outdoor strolling.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Charleston, SC to Indianapolis, IN
Showing times and prices for Jun 20
Cheapest price
$148
Average price
$148
Fastest journey
1 d 50 m
Average duration
1 d 5 h 30 m
Buses per day
2
Distance
957 km
Cheap tickets
The best way to find a cheap bus ticket from Charleston, SC to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, SC to Indianapolis, IN will cost around $148 if you buy it on the day, but the cheapest tickets can be found for only $148.
Fast buses
It's difficult to get from Charleston, SC to Indianapolis, IN without transferring at least once.
· 11:15 AM24h50Charleston, Gaynor Avenue (Greyhound Bus Station), SC12:05 PMIndianapolis, Illinois St (Greyhound Bus Station)$1481One-way1 transfer- · +
FlixBus11:15 AM34h10Charleston, Gaynor Avenue (Greyhound Bus Station), SC9:25 PMIndianapolis, E Washington St / N Delaware St (City/County Building), IN$1481One-way2 transfers
- · 11:15 AM24h50Charleston, Gaynor Avenue (Greyhound Bus Station), SC12:05 PMIndianapolis, Illinois St (Greyhound Bus Station)$1481One-way1 transfer
- · +FlixBus11:15 AM34h10Charleston, Gaynor Avenue (Greyhound Bus Station), SC9:25 PMIndianapolis, E Washington St / N Delaware St (City/County Building), IN$1481One-way2 transfers
Travel Information
Compare bus, flight, and train for Charleston, SC to Indianapolis, IN
Omio recommends booking the flight as it is the most popular option from Charleston, SC to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $113. For those with little time consider booking a flight which can get you there in 3h 3m. The ticket price range depends on the travel mode: a bus costs an average of $113, and a train costs an average of $462.
Distance: 594 miles (957 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$171 Average price Cheapest | $292 Average price | $462 Average price | $140 Average price (fuel + tolls) |
23h 55m Average total duration 23h 25m Onboard + 30m Additional time* | 6h 3m Average total duration Fastest 3h 3m Onboard + 3h 0m Additional time* | 33h 51m Average total duration 33h 21m Onboard + 30m Additional time* | 11h 3m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Charleston, SC to Indianapolis, IN is a bus with an average price of $171 (€140).
This is compared to other travel options from Charleston, SC to Indianapolis, IN:
A bus is $121 (€99) less than a flight for this route with tickets for a flight from Charleston, SC to Indianapolis, IN costing on average $292 (€239).
A bus is $291 (€238) less than a train for this route with tickets for a train from Charleston, SC to Indianapolis, IN costing on average $462 (€378).
The fastest way to travel from Charleston, SC to Indianapolis, IN is by flight with an average journey time of 3h 3m.
Other travel options to Indianapolis, IN take longer:
Bus takes on average 23h 25m.
Train takes on average 33h 21m.
It's helpful to compare your options as there are 3 ways to travel between Charleston, SC and Indianapolis, IN including taking a bus, flight, and train.
We recommend using the flight as it is the most popular way to get from Charleston, SC to Indianapolis, IN among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Charleston, SC to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 11:15AM | Arrival Time 12:05PM | Duration 24h50 | Departure days Everyday | Cheapest price $120 |
Live departures
Charleston, SC to Indianapolis, IN bus times
The table below shows live departures for Charleston, SC to Indianapolis, IN buses for tomorrow, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 11:15 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 24h50 | 12:05 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| · +FlixBus | 11:15 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 34h10 | 9:25 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Charleston, SC to Indianapolis, IN by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sat
Jun 20
Jun 20
Sun
Jun 21
Jun 21
Mon
Jun 22
Jun 22
Tue
Jun 23
Jun 23
Wed
Jun 24
Jun 24
Thu
Jun 25
Jun 25
Fri
Jun 26
Jun 26
Why should you book Charleston, SC to Indianapolis, IN buses with Omio?
Greyhound as well as CARTA offer buses services from Charleston, SC to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from Charleston, SC to Indianapolis, IN.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of CARTA to find the best option for your trip from Charleston, SC to Indianapolis, IN.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Charleston, SC to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Charleston, SC to Indianapolis, IN.
Journey information
Overview: Bus from Charleston, SC to Indianapolis, IN
USAUSA
Buses from Charleston, SC to Indianapolis, IN run on average 2 times per day, taking around 23h 25m. Cheap bus tickets for this journey start at $113 (€92) but you can travel from only $46 (€38) by flight.
The earliest bus runs at 00:15, the last at 23:30. The fastest bus covers the 594 miles (957 km) distance in 24h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $46 (€38)
Distance 594 miles (957 km) |
Average bus duration 23h 25m |
Cheapest ticket price $113 (€92) |
Buses per day 2 |
Fastest bus 24h 50m |
First bus 12:15 AM |
Last bus 11:30 PM |
Cheapest Month Nov |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $46 (€38)
Bus providers: Greyhound, CARTA from Charleston, SC to Indianapolis, INYou can travel by bus between Charleston, SC to Indianapolis, IN with Greyhound, CARTA for as low as $46 (€38). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
24h 50m
Cheapest Price
$113 (€92)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
CARTA
Luggage & cancellation policy
Average Duration
35h 20m
CARTA frequency
1 a day
Complete guide to Indianapolis
Things to do in Indianapolis
Discover the best of Indianapolis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis trip today.
- Must visit
The Children's Museum of Indianapolis
One of the world’s largest children’s museums, known for immersive science, history, and culture exhibits that also appeal to many adults.
- Recommended
Eiteljorg Museum
Respected museum focused on Native American and Western art, with strong permanent collections and rotating exhibitions.
- Must visit
Monument Circle
Iconic downtown circle and gathering place centered on the city’s best-known monument. A top orientation point and classic Indianapolis photo stop.
- Must visit
Canal Walk
Popular pedestrian route along the downtown canal, lined with museums, public art, paddle boats, and skyline views.
- Recommended
White River State Park
Large urban park complex connecting major attractions, trails, green spaces, and event venues near downtown.
Pork Tenderloin Sandwich
Indiana’s signature sandwich: a breaded and fried pork cutlet served on a bun, often comically larger than the bread. It is a classic Central Indiana comfort food.
- Gluten-free
Shrimp Cocktail
A St. Elmo Steak House staple in Indianapolis, known for jumbo shrimp served with an intensely spicy horseradish cocktail sauce. It is one of the city’s most famous signature dishes.
- Vegetarian
Sugar Cream Pie
Often called Indiana’s state pie, this simple custard-style pie is made with cream, sugar, and nutmeg. It is a beloved Hoosier dessert with deep local roots.
St. Elmo Steak House
Historic downtown steakhouse famous for shrimp cocktail, steaks, and classic old-school service. One of Indianapolis’s most iconic dining rooms.
Bluebeard
Well-known modern restaurant in Fletcher Place serving seasonal American cooking with a chef-driven menu in a stylish, industrial space.
Harry & Izzy's
Established upscale-casual spot related to St. Elmo, known for steaks, shrimp cocktail, and polished service in a more relaxed setting.
United States Dollar
Generally moderate for U.S. travel. Hotels vary by events; dining and transport are usually manageable.
Average meal costs
- Budget
- USD 10-15 for fast food or casual takeout.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 75+ per person before drinks and tax.
- Coffee
- USD 4-6 for a regular coffee or latte.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 2-5, and round up for cafes if desired.
FAQs: Bus from Charleston, SC to Indianapolis, IN
Find answers to the most common questions about traveling from Charleston, SC to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Charleston, SC to Indianapolis, IN can start from as little as $113 (€92) when you book in advance. The average bus ticket price for Charleston, SC to Indianapolis, IN is $171 (€140) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Charleston, SC to Indianapolis, IN is 24h 50m to travel the 594 miles (957 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Charleston, SC to Indianapolis, IN leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Charleston, SC to Indianapolis, IN leaves at 11:30 PM.
There are 2 buses a day from Charleston, SC to Indianapolis, IN which require at least one change with Greyhound, CARTA. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Charleston, SC to Indianapolis, IN, you can count on Greyhound, CARTA for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between Charleston, SC and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
A trip to Indianapolis, IN from Charleston, SC is worth doing but not as a day trip with a journey time of 24h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Charleston, SC to Indianapolis, IN is November.
It's helpful to compare your options as there are 3 ways to travel between Charleston, SC and Indianapolis, IN including taking a bus, flight, and train.
Yes, there are bathrooms on board the bus from Charleston, SC to Indianapolis, IN for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Charleston, SC to Indianapolis, IN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Indianapolis, IN are:
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best things to do in Indianapolis, IN include:
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
Whether you can cancel your bus ticket from Charleston, SC to Indianapolis, IN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Charleston, SC to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from Charleston, SC to Indianapolis, IN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Charleston, SC to Indianapolis, IN:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Charleston, SC to Indianapolis, IN.
You can reserve your seat on the bus from Charleston, SC to Indianapolis, IN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Charleston, SC to Indianapolis, IN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Charleston, SC to Indianapolis, IN with the following bus company: Greyhound.
Since neither Charleston, SC nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Charleston, SC to Indianapolis, IN among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Charleston, SC to Indianapolis, IN
Most Charleston, SC to Indianapolis, IN buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Indianapolis, Illinois St (Greyhound Bus Station) station pair, with some services arriving at Indianapolis, E Washington St / N Delaware St (City/County Building). Use this guide to compare Charleston, SC and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Charleston
Arrival bus stations in Indianapolis
Charleston, Gaynor Avenue (Greyhound Bus Station)
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Indianapolis, Illinois St (Greyhound Bus Station)
Indianapolis, E Washington St / N Delaware St (City/County Building)
Most popular bus connections from Charleston, SC
More options for your journey from Charleston, SC to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular buses to and from Indianapolis, IN and Charleston, SC
Most popular bus connections to Indianapolis, IN
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
