- Must visit
Mint Museum Uptown
Major Uptown museum for European, American, and contemporary art. Its collection and architecture make it Charlotte's top fine-arts stop.
Cheapest price on Sep 19
Kč932
Average ticket price on Sep 19
Kč953
Fastest journey on Sep 19
6 h 50 m
Average journey duration on Sep 19
10 h
Buses on Sep 19
3
Distance
285 km
The best way to find a cheap bus ticket from Charleston, SC to Charlotte, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, SC to Charlotte, NC will cost around Kč953 if you buy it on the day, but the cheapest tickets can be found for only Kč932.
On Sat, Sep 19, we found 3 buses from Charleston, SC to Charlotte, NC, including 1 direct services.
On Sat, Sep 19 the direct buses cover the 285 km distance in an average of 10 h but if you time it right, some buses will get you there in just 6 h 50 m .
On Sat, Sep 19 the slowest buses will take 12 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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FlixBus
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FlixBusOmio recommends booking the flight as it is the most popular option from Charleston, SC to Charlotte, NC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of Kč1333 For those with little time, consider booking a flight, which has an average total journey time of 5h 11m. Average ticket prices depend on the travel mode: a bus costs an average of Kč1333, while a flight costs an average of Kč12495.
Distance: 177 miles (285 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
Kč1333 Average price Cheapest | Kč12495 Average price | Kč5290 Average price | Kč904 Average price (fuel + tolls) |
8h 8m Average total duration 7h 38m Onboard + 30m Additional time* | 5h 11m Average total duration Fastest 3h 11m Onboard + 2h 0m Additional time* | 13h 5m Average total duration 12h 35m Onboard + 30m Additional time* | 3h 19m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Charleston, SC to Charlotte, NC:
A bus is Kč3957 less than a train for this route with tickets for a train from Charleston, SC to Charlotte, NC costing on average Kč5290.
A bus is Kč11162 less than a flight for this route with tickets for a flight from Charleston, SC to Charlotte, NC costing on average Kč12495.
Other travel options to Charlotte, NC take longer:
Bus takes on average 7h 38m.
Train takes on average 12h 35m.
Tickets start at around Kč1333 compared to roughly Kč904 in fuel and tolls — a saving of about Kč-429.32. The journey takes 7h 38m versus 3h 19m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 09:15AM | Arrival Time 04:05PM | Duration 6h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price Kč880 |
Operator Greyhound | Departure Time 09:30AM | Arrival Time 04:05PM | Duration 6h35 | Departure days Sun | Cheapest price Kč1009 |
Operator Greyhound | Departure Time 10:00AM | Arrival Time 09:00PM | Duration 11h00 | Departure days Everyday | Cheapest price Kč815 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 12:30AM | Duration 12h10 | Departure days Everyday | Cheapest price Kč828 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 12:30AM | Duration 11h40 | Departure days Sun | Cheapest price Kč1100 |
The table below shows live departures for Charleston, SC to Charlotte, NC buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:15 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 6h50 | 4:05 PM Charlotte, W 4th St (Greyhound Bus Station) | 0 transfersDirect | |
· · | 10:00 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 11h00 | 9:00 PM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
FlixBus+![]() | 12:20 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 12h10 | 12:30 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Charleston, SC to Charlotte, NC run on average 1 times per day, taking around 7h 38m. Cheap bus tickets for this journey start at Kč769 if you book in advance.
The earliest bus runs at 11:15, the last at 13:55. The fastest bus covers the 177 miles (285 km) distance in 6h 35m.
Distance 177 miles (285 km) |
Average bus duration 7h 38m |
Cheapest ticket price Kč769 |
Buses per day 1 |
Fastest bus 6h 35m |
First bus 11:15 AM |
Last bus 1:55 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 14 days |
Discover the best of Charlotte, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charlotte, NC trip today.
Major Uptown museum for European, American, and contemporary art. Its collection and architecture make it Charlotte's top fine-arts stop.
Leading center for African American arts and culture, featuring exhibitions, performances, and powerful stories from Charlotte and beyond.
Regional science museum with hands-on exhibits, live demonstrations, and an IMAX Dome. Great for families and curious adults alike.
Charlotte's central business district mixes museums, plazas, public art, and skyline views. Essential for first-time visitors exploring the city core.
Creative historic district packed with murals, music venues, design shops, and converted mills. Ideal for art, walking, and local culture.
Trendy neighborhood known for rail-trail walking, street art, breweries, and restored industrial spaces. One of Charlotte's liveliest areas.
Slow-smoked chopped or pulled pork with a tangy vinegar sauce, a Carolina barbecue staple widely loved across Charlotte.
Smoky pit-cooked pork shoulder finished with mustard-based sauce, reflecting South Carolina influence common in Charlotte.
Deep-fried catfish, often served with hush puppies and slaw. It is a classic Southern comfort dish popular in the Charlotte region.
Historic barbecue spot famed for Carolina chopped pork, red slaw, and old-school Southern atmosphere.
Lively Southern dining room serving fried chicken, biscuits, shrimp and grits, and regional cocktails in South End.
Refined Southern restaurant in Uptown known for shrimp and grits, local ingredients, and an elegant modern setting.
Moderate for a major U.S. city. Hotels and dining are mid-priced, transit is affordable, and attractions often cost less than in larger hubs like New York or San Francisco.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee in cafes if service is provided.
Find answers to the most common questions about traveling from Charleston, SC to Charlotte, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charlotte, NC, this guide helps you travel smarter and with confidence.

Most Charleston, SC to Charlotte, NC buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Charlotte, W 4th St (Greyhound Bus Station) station pair. Use this guide to compare Charleston, SC and Charlotte, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Charlotte, W 4th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Charlotte, W 4th St (Greyhound Bus Station). ATMs are available at Charlotte, W 4th St (Greyhound Bus Station).
Ticket office support is available at Charlotte, W 4th St (Greyhound Bus Station).
Available at Charlotte, W 4th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charlotte, W 4th St (Greyhound Bus Station): The station is wheelchair accessible.
Here are some other resources that might have the information you need