The cheapest and fastest buses from Charleston, SC to Jacksonville, FL
Cheapest price
$53
Average price
$53
Fastest journey
5 h 5 m
Average duration
5 h 5 m
Buses per day
1
Distance
317 km
The best way to find a cheap bus ticket from Charleston, SC to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, SC to Jacksonville, FL will cost around $53 if you buy it on the day, but the cheapest tickets can be found for only $53.
Of the 1 buses that leave Charleston, SC for Jacksonville, FL on Thu, Jan 29, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jan 29 the direct buses cover the 317 km distance in an average of 5 h 5 m but if you time it right, some buses will get you there in just 5 h 5 m .
On Thu, Jan 29 the slowest buses will take 5 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Charleston, SC to Jacksonville, FL
Omio recommends booking the train as it is the most popular option from Charleston, SC to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from €30. For those with little time consider booking a train which can get you there in 4h 26m. The ticket price range depends on the travel mode: a bus costs an average of €30, and a flight costs an average of €111.
Distance: 196 miles (317 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€41 Average price Cheapest | €65 Average price | €254 Average price |
5h 35m Average total duration 5h 5m Onboard + 30m Additional time* | 4h 56m Average total duration Fastest 4h 26m Onboard + 30m Additional time* | 9h 23m Average total duration 6h 23m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Charleston, SC to Jacksonville, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:15AM | Arrival Time 09:25PM | Duration 10h10 | Departure days Mon, Tue | Cheapest price $94 |
Live departures
Charleston, SC to Jacksonville, FL bus times
The table below shows live departures for Charleston, SC to Jacksonville, FL buses for today, Wednesday, January 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:15 PM Charleston, SC | 5h05 | 12:20 AM Jacksonville, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Charleston, SC to Jacksonville, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 29
Jan 30
Jan 31
Feb 01
Feb 02
Feb 03
Feb 04
Why should you book Charleston, SC to Jacksonville, FL buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of CARTA to find the best option for your trip from Charleston, SC to Jacksonville, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Charleston, SC to Jacksonville, FL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Charleston, SC to Jacksonville, FL.
Journey information
Overview: Bus from Charleston, SC to Jacksonville, FL
Buses from Charleston, SC to Jacksonville, FL run on average 1 times per day, taking around 5h 5m. Cheap bus tickets for this journey start at $38 (€30) if you book in advance.
There are 1 buses per day. The earliest bus runs at 08:45, the last at 15:15. The fastest bus covers the 196 miles (317 km) distance in 5h 5m.
Distance 196 miles (317 km) |
Average bus duration 5h 5m |
Cheapest ticket price $38 (€30) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 5h 5m |
First bus 08:45 |
Last bus 15:15 |
Bus providers: Greyhound, CARTA from Charleston, SC to Jacksonville, FLYou can travel by bus between Charleston, SC to Jacksonville, FL with Greyhound, CARTA for as low as $38 (€30). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
CARTA
FAQs: Bus from Charleston, SC to Jacksonville, FL
Find answers to the most common questions about traveling from Charleston, SC to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Charleston, SC to Jacksonville, FL
Most popular bus connections from Charleston, SC
More options for your journey from Charleston, SC to Jacksonville, FL
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