The cheapest and fastest buses from Charleston, SC to Jacksonville, FL
Cheapest price
$109
Average price
$109
Fastest journey
10 h 10 m
Average duration
10 h 10 m
Buses per day
1
Distance
317 km
The best way to find a cheap bus ticket from Charleston, SC to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, SC to Jacksonville, FL will cost around $109 if you buy it on the day, but the cheapest tickets can be found for only $109.
It's difficult to get from Charleston, SC to Jacksonville, FL without transferring at least once.
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FlixBus11:15 AM10h10Charleston, Gaynor Avenue (Greyhound Bus Station), SC9:25 PMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$1091One-way1 transfer
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FlixBus11:15 AM10h10Charleston, Gaynor Avenue (Greyhound Bus Station), SC9:25 PMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$1091One-way1 transfer
Travel Information
Compare bus, train, and flight for Charleston, SC to Jacksonville, FL
Omio recommends booking the train as it is the most popular option from Charleston, SC to Jacksonville, FL among Omio's users. If you are prioritising price take the train with prices starting from $54. For those with little time consider booking a flight which can get you there in 2h 34m. The ticket price range depends on the travel mode: a train costs an average of $54, and a flight costs an average of $144.
Distance: 196 miles (317 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$124 Average price | $86 Average price Cheapest | $347 Average price |
5h 35m Average total duration 5h 5m Onboard + 30m Additional time* | 4h 56m Average total duration 4h 26m Onboard + 30m Additional time* | 5h 34m Average total duration Fastest 2h 34m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Charleston, SC to Jacksonville, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:15AM | Arrival Time 09:25PM | Duration 10h10 | Departure days Wed, Thu, Fri | Cheapest price $109 |
Live departures
Charleston, SC to Jacksonville, FL bus times
The table below shows live departures for Charleston, SC to Jacksonville, FL buses for today, Wednesday, April 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 11:15 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 10h10 | 9:25 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Charleston, SC to Jacksonville, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 30
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Why should you book Charleston, SC to Jacksonville, FL buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of CARTA to find the best option for your trip from Charleston, SC to Jacksonville, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Charleston, SC to Jacksonville, FL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Charleston, SC to Jacksonville, FL.
Journey information
Overview: Bus from Charleston, SC to Jacksonville, FL
Buses from Charleston, SC to Jacksonville, FL run on average 1 times per day, taking around 5h 5m. Cheap bus tickets for this journey start at $43 (€35) if you book in advance.
The earliest bus runs at 08:15, the last at 15:15. The fastest bus covers the 196 miles (317 km) distance in 9h 50m.
Distance 196 miles (317 km) |
Average bus duration 5h 5m |
Cheapest ticket price $43 (€35) |
Buses per day 1 |
Fastest bus 9h 50m |
First bus 8:15 AM |
Last bus 3:15 PM |
Cheapest Month May |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Sun |
Bus providers: Greyhound, CARTA from Charleston, SC to Jacksonville, FLYou can travel by bus between Charleston, SC to Jacksonville, FL with Greyhound, CARTA for as low as $43 (€35). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
CARTA
FAQs: Bus from Charleston, SC to Jacksonville, FL
Find answers to the most common questions about traveling from Charleston, SC to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Charleston, SC to Jacksonville, FL
Most popular bus connections from Charleston, SC
More options for your journey from Charleston, SC to Jacksonville, FL
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