Travel Information
Compare bus, flight, and train for Charleston, SC to Indianapolis, IN
Omio recommends booking the flight as it is the most popular option from Charleston, SC to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $114. For those with little time consider booking a flight which can get you there in 3h 3m. The ticket price range depends on the travel mode: a bus costs an average of $114, and a train costs an average of $468.
Distance: 594 miles (957 km)
Compare train with
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$468 Average price | $296 Average price | $173 Average price Cheapest | $142 Average price (fuel + tolls) |
33h 51m Average total duration 33h 21m Onboard + 30m Additional time* | 6h 3m Average total duration Fastest 3h 3m Onboard + 3h 0m Additional time* | 23h 55m Average total duration 23h 25m Onboard + 30m Additional time* | 11h 3m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Charleston, SC to Indianapolis, IN:
A bus is $122 (€99) less than a flight for this route with tickets for a flight from Charleston, SC to Indianapolis, IN costing on average $296 (€239).
A bus is $295 (€238) less than a train for this route with tickets for a train from Charleston, SC to Indianapolis, IN costing on average $468 (€378).
Other travel options to Indianapolis, IN take longer:
Bus takes on average 23h 25m.
Train takes on average 33h 21m.
Tickets start at around $468 (€378) compared to roughly $142 (€115) in fuel and tolls — a saving of about $-325.83 (€-263.13). The journey takes 33h 21m versus 11h 3m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare prices and tickets Charleston, SC to Indianapolis, IN by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 18
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Journey information
Overview: Train from Charleston, SC to Indianapolis, IN
Trains from Charleston, SC to Indianapolis, IN run on average 1 times per day, taking around 33h 21m. Cheap train tickets for this journey start at $468 (€378) but you can travel from only $47 (€38) by flight.
The earliest train runs at 00:15, the last at 21:34. The fastest train covers the 594 miles (957 km) distance in 33h 21m.
Distance 594 miles (957 km) |
Average train duration 33h 21m |
Cheapest ticket price $468 (€378) |
Trains per day 1 |
Fastest train 33h 21m |
First train 12:15 AM |
Last train 9:34 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jul - Sep |
FAQs: Trains from Charleston, SC to Indianapolis, IN
Find answers to the most common questions about traveling from Charleston, SC to Indianapolis, IN by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Charleston, SC to Indianapolis, IN
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available a few blocks away from the station.
- Harry & Izzy's
- St. Elmo Steak House
- Outside the main entrance.
- Ramps.
- Free for passengers
- Crowne Plaza Indianapolis-Dwtn-Union-Stn
- Omni Severin Hotel
- The Westin Indianapolis
- Located in the main hall
- Free
- Hall 1: main entrance, platform for Amtrak's Cardinal line
- Bus: IndyGo routes available nearby
More options for your journey from Charleston, SC to Indianapolis, IN
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