- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Cheapest price on Oct 30
$83
Average ticket price on Oct 30
$101
Fastest journey on Oct 30
11 h 35 m
Average journey duration on Oct 30
17 h 11 m
Buses on Oct 30
5
Distance
491 km
The best way to find a cheap bus ticket from Charleston, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, SC to Orlando, FL will cost around $101 if you buy it on the day, but the cheapest tickets can be found for only $83.
It's difficult to get from Charleston, SC to Orlando, FL without transferring at least once.
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Buses from Charleston, SC to Orlando, FL run on average 2 times per day, taking around 14h 41m. Cheap bus tickets for this journey start at $54 but you can travel from only $40 by flight.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 305 miles (491 km) distance in 7h 30m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Charleston, SC to Orlando, FL.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 10:00AM | Arrival Time 07:50AM | Duration 21h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $68 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 09:15PM | Duration 8h55 | Departure days Tue | Cheapest price $69 |
Operator FlixBus | Departure Time 01:50PM | Arrival Time 01:50AM | Duration 12h00 | Departure days Fri, Sat | Cheapest price $81 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 01:50AM | Duration 11h35 | Departure days Mon, Thu, Fri, Sun | Cheapest price $85 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 04:55AM | Duration 13h40 | Departure days Wed | Cheapest price $138 |
Operator Greyhound | Departure Time 04:15PM | Arrival Time 04:10PM | Duration 23h55 | Departure days Wed | Cheapest price $145 |
The table below shows live departures for Charleston, SC to Orlando, FL buses for today, Thursday, October 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 10:00 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 21h50 | 7:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
+ FlixBus | 10:00 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 20h25 | 6:25 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 2:15 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 11h35 | 1:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Charleston, SC to Orlando, FL with FlixBus and Greyhound. Overnight buses available on this route with FlixBus and Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Orlando, FL.
Find answers to the most common questions about traveling from Charleston, SC to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most Charleston, SC to Orlando, FL buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair. Use this guide to compare Charleston, SC and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Check bus stations information for Charleston, SC and Orlando, FL, including where buses depart and arrive on this route.