- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Cheapest price
$131
Average price
$142
Fastest journey
8 h 25 m
Average duration
14 h 30 m
Buses per day
2
Distance
491 km
The best way to find a cheap bus ticket from Charleston, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, SC to Orlando, FL will cost around $142 if you buy it on the day, but the cheapest tickets can be found for only $131.
It's difficult to get from Charleston, SC to Orlando, FL without transferring at least once.
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FlixBus
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FlixBus
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FlixBus
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FlixBusBuses from Charleston, SC to Orlando, FL run on average 2 times per day, taking around 10h 26m. Cheap bus tickets for this journey start at $60 but you can travel from only $52 by flight.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 305 miles (491 km) distance in 13h 40m.
Distance 305 miles (491 km) |
Average bus duration 10h 26m |
Cheapest ticket price $60 |
Buses per day 2 |
Fastest bus 13h 40m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 42 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 11:15AM | Arrival Time 07:50AM | Duration 20h35 | Departure days Everyday | Cheapest price $87 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 09:15PM | Duration 8h25 | Departure days Everyday | Cheapest price $81 |
The table below shows live departures for Charleston, SC to Orlando, FL buses for tomorrow, Friday, July 31. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 11:15 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 20h35 | 7:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
+ FlixBus | 12:50 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 8h25 | 9:15 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Find answers to the most common questions about traveling from Charleston, SC to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most Charleston, SC to Orlando, FL buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair. Use this guide to compare Charleston, SC and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
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