- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Cheapest price on Sep 14
$102
Average ticket price on Sep 14
$135
Fastest journey on Sep 14
8 h 55 m
Average journey duration on Sep 14
15 h 23 m
Buses on Sep 14
2
Distance
491 km
The best way to find a cheap bus ticket from Charleston, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, SC to Orlando, FL will cost around $135 if you buy it on the day, but the cheapest tickets can be found for only $102.
It's difficult to get from Charleston, SC to Orlando, FL without transferring at least once.
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FlixBus
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FlixBus
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FlixBus
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FlixBusOmio recommends booking the train as it is the most popular option from Charleston, SC to Orlando, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $120 For those with little time, consider booking a flight, which has an average total journey time of 5h 22m. Average ticket prices depend on the travel mode: a bus costs an average of $120, while a flight costs an average of $445.
Distance: 305 miles (491 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$120 Average price Cheapest | $146 Average price | $445 Average price | $78 Average price (fuel + tolls) |
16h 13m Average total duration 15h 43m Onboard + 30m Additional time* | 8h 33m Average total duration 8h 3m Onboard + 30m Additional time* | 5h 22m Average total duration Fastest 3h 22m Onboard + 2h 0m Additional time* | 5h 58m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Charleston, SC to Orlando, FL:
A bus is $26 (€21) less than a train for this route with tickets for a train from Charleston, SC to Orlando, FL costing on average $146 (€118).
A bus is $324 (€262) less than a flight for this route with tickets for a flight from Charleston, SC to Orlando, FL costing on average $445 (€359).
Other travel options to Orlando, FL take longer:
Train takes on average 8h 3m.
Bus takes on average 15h 43m.
Tickets start at around $120 (€97) compared to roughly $78 (€63) in fuel and tolls — a saving of about $-41.85 (€-33.84). The journey takes 15h 43m versus 5h 58m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 10:00AM | Arrival Time 07:50AM | Duration 21h50 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $99 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 09:15PM | Duration 8h55 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $80 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 04:55AM | Duration 13h40 | Departure days Sat, Sun | Cheapest price $130 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 05:55AM | Duration 13h40 | Departure days Sun | Cheapest price $181 |
Operator Greyhound | Departure Time 04:15PM | Arrival Time 04:10PM | Duration 23h55 | Departure days Sat | Cheapest price $189 |
The table below shows live departures for Charleston, SC to Orlando, FL buses for tomorrow, Monday, September 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 10:00 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 21h50 | 7:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
+ FlixBus | 12:20 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 8h55 | 9:15 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Charleston, SC to Orlando, FL run on average 2 times per day, taking around 15h 43m. Cheap bus tickets for this journey start at $53 (€43) but you can travel from only $42 (€34) by flight.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 305 miles (491 km) distance in 7h 30m.
Distance 305 miles (491 km) |
Average bus duration 15h 43m |
Cheapest ticket price $53 (€43) |
Buses per day 2 |
Fastest bus 7h 30m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Wed |
Best time to book 6 days |
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Find answers to the most common questions about traveling from Charleston, SC to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most Charleston, SC to Orlando, FL buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair. Use this guide to compare Charleston, SC and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
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