- Must visit
The Walters Art Museum
Major free art museum with collections spanning ancient, medieval, Renaissance, and Asian art in Mount Vernon.
Cheapest price
$161
Average price
$161
Fastest journey
16 h 55 m
Average duration
16 h 55 m
Buses per day
1
Distance
783 km
The best way to find a cheap bus ticket from Charleston, SC to Baltimore, MD is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, SC to Baltimore, MD will cost around $161 if you buy it on the day, but the cheapest tickets can be found for only $161.
It's difficult to get from Charleston, SC to Baltimore, MD without transferring at least 2 times.
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FlixBus
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FlixBusOmio recommends booking the train as it is the most popular option from Charleston, SC to Baltimore, MD among Omio's users. If you are prioritising price take the bus with prices starting from $95. For those with little time consider booking a flight which can get you there in 6h 47m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of $95, and a flight costs an average of $87.
Distance: 486 miles (783 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$179 Average price Cheapest | $185 Average price | $350 Average price | $108 Average price (fuel + tolls) |
16h 51m Average total duration 16h 21m Onboard + 30m Additional time* | 11h 45m Average total duration 11h 15m Onboard + 30m Additional time* | 9h 47m Average total duration Fastest 6h 47m Onboard + 3h 0m Additional time* | 8h 38m Average total duration (door-to-door) |
0.8 - 2.0kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | 2.3 - 4.7kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Charleston, SC to Baltimore, MD:
A bus is $7 (€5) less than a train for this route with tickets for a train from Charleston, SC to Baltimore, MD costing on average $185 (€152).
A bus is $171 (€140) less than a flight for this route with tickets for a flight from Charleston, SC to Baltimore, MD costing on average $350 (€286).
Other travel options to Baltimore, MD take longer:
Train takes on average 11h 15m.
Bus takes on average 16h 21m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:15AM | Arrival Time 04:10AM | Duration 16h55 | Departure days Everyday | Cheapest price $127 |
The table below shows live departures for Charleston, SC to Baltimore, MD buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · | 11:15 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 16h55 | 4:10 AM Baltimore, Haines St (Baltimore Downtown Bus Station) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Charleston, SC to Baltimore, MD run on average 1 times per day, taking around 16h 21m. Cheap bus tickets for this journey start at $95 (€78) but you can travel from only $87 (€71) by flight.
The earliest bus runs at 00:25, the last at 23:45. The fastest bus covers the 486 miles (783 km) distance in 16h 20m.
Distance 486 miles (783 km) |
Average bus duration 16h 21m |
Cheapest ticket price $95 (€78) |
Buses per day 1 |
Fastest bus 16h 20m |
First bus 12:25 AM |
Last bus 11:45 PM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 4 days |
Discover the best of Baltimore — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Baltimore trip today.
Major free art museum with collections spanning ancient, medieval, Renaissance, and Asian art in Mount Vernon.
Leading art museum known for its Cone Collection, contemporary works, and sculpture garden near Johns Hopkins.
Distinctive museum dedicated to self-taught artists, with imaginative exhibitions and a whimsical outdoor setting.
Baltimore's best-known waterfront district with promenades, harbor views, museums, and easy access to major attractions.
Historic waterfront neighborhood known for cobblestone streets, maritime character, and lively local atmosphere.
Popular hilltop park with one of the city's classic skyline and harbor viewpoints, especially photogenic at sunset.
Broiled or lightly fried cakes made with sweet blue crab meat and minimal filler. They are one of Baltimore’s signature foods and a classic Chesapeake Bay specialty.
Whole blue crabs steamed and coated with a bold spice blend, often eaten communally at crab houses. This is a defining Baltimore seafood tradition.
Baltimore barbecue specialty of charcoal-grilled roast beef sliced thin and served on a roll, often with raw onion and horseradish or tiger sauce.
Classic upscale steakhouse with old-school service, live music, and a refined atmosphere. A Baltimore institution for fine dining and cocktails.
Historic Lexington Market seafood counter famous for jumbo lump crab cakes. Casual, bustling, and one of the city’s most iconic food stops.
Popular local cafe known for elevated Chesapeake-inspired brunch dishes, crab specials, and friendly, lively service.
Moderate by U.S. standards. Hotels and dining vary by area; seafood and downtown spots cost more.
Tip 18-20% in restaurants; 20%+ for great service. USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Charleston, SC to Baltimore, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Baltimore, MD, this guide helps you travel smarter and with confidence.

Most Charleston, SC to Baltimore, MD buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Baltimore, Haines St (Baltimore Downtown Bus Station) station pair. Use this guide to compare Charleston, SC and Baltimore, MD bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need