Charleston, SC to Chicago, IL bus with Greyhound

Thu, Nov 27
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Greyhound
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FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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Travel Information

Compare bus for Charleston, SC to Chicago, IL

Omio recommends booking the flight as it is the most popular option from Charleston, SC to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €167. For those with little time consider booking a flight which can get you there in 3h 39m. The ticket price range depends on the travel mode: a bus costs an average of €167, and a flight costs an average of €358.

Distance: 756 miles (1217 km)

Compare bus with

Bus
Most popular
Flight

€167

Average price

Cheapest

€358

Average price

24h 43m

Average total duration

24h 13m

Onboard

+

30m

Additional time*

6h 39m

Average total duration

Fastest

3h 39m

Onboard

+

3h 0m

Additional time*

Greyhound

Most popular bus company

American Airlines

Most popular airline

Direct Options

Direct Options

Compare prices and tickets Charleston, SC to Chicago, IL by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Nov 28
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Nov 29
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Nov 30
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Dec 01
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Dec 04

Journey information

Overview: Bus from Charleston, SC to Chicago, IL

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Buses from Charleston, SC to Chicago, IL run on average 2 times per day, taking around 24h 13m. Cheap bus tickets for this journey start at $206 (€167) if you book in advance.

The earliest bus runs at 10:00, the last at 22:00. The fastest bus covers the 756 miles (1217 km) distance in 41h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
756 miles (1217 km)
Average bus duration
24h 13m
Cheapest ticket price
$206 (€167)
Buses per day
2
Fastest bus
41h 35m
First bus
10:00
Last bus
22:00
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Charleston, SC to Chicago, ILYou can travel by bus between Charleston, SC to Chicago, IL with Greyhound for as low as $206 (€167). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
25h 0m
Cheapest Price
$204 (€166)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Charleston, SC to Chicago, IL

Find answers to the most common questions about traveling from Charleston, SC to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Charleston, SC to Chicago, IL can start from as little as $189 (€153) when you book in advance. The average bus ticket price for Charleston, SC to Chicago, IL is $204 (€165); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Charleston, SC to Chicago, IL bus time is 43 h 10 min   covering the 754 mile (1216 km) long journey, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Charleston, SC to Chicago, IL leaves at 2: 00AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Charleston, SC to Chicago, IL leaves at 10: 50PM.
There are 3 buses a day from Charleston, SC to Chicago, IL which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
Take the Charleston, SC to Chicago, IL bus with Greyhound. However, it's always good to check out all possible bus providers for the route between Charleston, SC and Chicago, IL as there might be differences in the amenities they offer.
The cheapest month to travel from Charleston, SC to Chicago, IL by bus is December.
Yes, you can take a bus to Chicago, IL from Charleston, SC.
Yes, the following accessibility options are available when taking the bus from Charleston, SC to Chicago, IL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Charleston, SC to Chicago, IL for bus company Greyhound.
Some of the most interesting sights to explore in Chicago, IL are:
  • Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
  • Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
  • Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
  • Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
  • Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
The best things to do in Chicago, IL include:
  • Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
  • Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
  • Take a river cruise to see the city's iconic architecture from a different perspective
  • Attend a live performance at the historic Chicago Theatre
  • Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from Charleston, SC to Chicago, IL depends on the bus company:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from Charleston, SC to Chicago, IL, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Charleston, SC to Chicago, IL.
    Yes, the following luggage options are included when booking a bus ticket from Charleston, SC to Chicago, IL:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Charleston, SC to Chicago, IL:
    • Greyhound
      • $15 per additional bag.
    Unfortunately, pets are not allowed on the bus from Charleston, SC to Chicago, IL.
    You can reserve your seat on the bus from Charleston, SC to Chicago, IL with the following bus company: Greyhound
    Yes, there are USB plugs on board the bus from Charleston, SC to Chicago, IL with the following bus company: Greyhound.
    Yes, there is Wifi on board the bus from Charleston, SC to Chicago, IL with the following bus company: Greyhound.

    popular bus stations

    Popular bus stations from Charleston, SC to Chicago, IL

    Charleston
    Chicago
    The major bus station for departures in Charleston is Charleston, Gaynor Avenue (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Charleston, Gaynor Avenue (Greyhound Bus Station) for your trip from Charleston to Chicago.
    Charleston, Gaynor Avenue (Greyhound Bus Station)
    information

    Most popular bus connections from Charleston, SC

    More options for your journey from Charleston, SC to Chicago, IL

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