Charleston, SC CHS to Indianapolis, IN IND flight with Republic Airlines

Thu, Aug 06
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The cheapest and fastest flights from Charleston, SC to Indianapolis, IN

Showing times and prices for Aug 06

Cheapest price

$336

Average price

$501

Fastest journey

3 h 25 m

Average duration

3 h 57 m

Flights per day

53

Distance

957 km

Cheap tickets

The best way to find a cheap flight ticket from Charleston, SC to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Charleston, SC to Indianapolis, IN will cost around $501 if you buy it on the day, but the cheapest tickets can be found for only $336.

Fast flights

It's difficult to get from Charleston, SC to Indianapolis, IN without transferring at least once.

  • UnitedUA592 · UA5985
    11:31 AM6h21
    Charleston International Airport
    5:52 PMIndianapolis International Airport
    $3361One-way
    1 transfer
  • UnitedUA3426 · UA3455
    3:08 PM5h05
    Charleston International Airport
    8:13 PMIndianapolis International Airport
    $3361One-way
    1 transfer
  • UnitedUA4322 · UA4021
    7:46 PM4h13
    Charleston International Airport
    11:59 PMIndianapolis International Airport
    $3361One-way
    1 transfer
  • UnitedUA592 · UA587
    11:31 AM4h59
    Charleston International Airport
    4:30 PMIndianapolis International Airport
    $3361One-way
    1 transfer
  • UnitedUA2693 · UA3519
    3:34 PM5h23
    Charleston International Airport
    8:57 PMIndianapolis International Airport
    $3361One-way
    1 transfer

Journey information

Overview: Charleston, SC to Indianapolis, IN flight

USAUSA
USAUSA
Icon of flight

Flights from Charleston, SC to Indianapolis, IN depart on average 47 times per day, taking around 3h 3m. Cheap flight tickets for this journey start at $47 if you book in advance.

The earliest flight runs at 05:00, the last at 22:10. The fastest flight covers the 594 miles (957 km) distance in 4h 12m. May is the cheapest month to fly.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
594 miles (957 km)
Average flight duration
3h 3m
Cheapest ticket price
$47
Flights per day
47
Fastest flight
4h 12m
First flight
5:00 AM
Last flight
10:10 PM
Cheapest Month
May
Cheapest Day
Sat
High Season
Apr - Jun
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Live departures

Charleston, SC to Indianapolis, IN flight times

The table below shows live departures for Charleston, SC to Indianapolis, IN flights for today, Wednesday, August 5. You can also manually refresh the results below to see updated flight journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
UnitedUA2333 · UA2277 · UA34026:00 AM Charleston International Airport
8h29
2:29 PM Indianapolis International Airport2 transfers
UnitedUA2333 · UA59686:00 AM Charleston International Airport
6h54
12:54 PM Indianapolis International Airport1 transfer
UnitedUA1289 · UA1691 · UA34026:00 AM Charleston International Airport
8h29
2:29 PM Indianapolis International Airport2 transfers
UnitedUA1289 · UA2290 · UA37026:00 AM Charleston International Airport
9h03
3:03 PM Indianapolis International Airport2 transfers
UnitedUA1289 · UA1525 · UA37026:00 AM Charleston International Airport
9h03
3:03 PM Indianapolis International Airport2 transfers
UnitedUA1289 · UA1525 · UA5876:00 AM Charleston International Airport
10h30
4:30 PM Indianapolis International Airport2 transfers
UnitedUA1289 · UA36696:00 AM Charleston International Airport
6h05
12:05 PM Indianapolis International Airport1 transfer
American AirlinesAA2773+Republic AirlinesAA47016:00 AM Charleston International Airport
6h04
12:04 PM Indianapolis International Airport1 transfer
American AirlinesAA1721 · AA8466:15 AM Charleston International Airport
6h05
12:20 PM Indianapolis International Airport1 transfer
American AirlinesAA1721 · AA14106:15 AM Charleston International Airport
4h05
10:20 AM Indianapolis International Airport1 transfer
American AirlinesAA1721 · AA1581+Republic AirlinesAA47016:15 AM Charleston International Airport
5h49
12:04 PM Indianapolis International Airport2 transfers
Republic AirlinesAA4580 · AA45656:24 AM Charleston International Airport
5h37
12:01 PM Indianapolis International Airport1 transfer
American AirlinesAA3266 · AA29217:00 AM Charleston International Airport
4h32
11:32 AM Indianapolis International Airport1 transfer
American AirlinesAA3266 · AA24187:00 AM Charleston International Airport
12h38
7:38 PM Indianapolis International Airport1 transfer
American AirlinesAA1526+psa airlinesAA52407:33 AM Charleston International Airport
5h26
12:59 PM Indianapolis International Airport1 transfer
American AirlinesAA1731 · AA8468:12 AM Charleston International Airport
4h08
12:20 PM Indianapolis International Airport1 transfer
American AirlinesAA1589+psa airlinesAA567210:12 AM Charleston International Airport
5h15
3:27 PM Indianapolis International Airport1 transfer
UnitedUA1858 · UA340210:13 AM Charleston International Airport
4h16
2:29 PM Indianapolis International Airport1 transfer
UnitedUA1858 · UA1498 · UA344310:13 AM Charleston International Airport
7h53
6:06 PM Indianapolis International Airport2 transfers
UnitedUA1858 · UA2331 · UA341810:13 AM Charleston International Airport
8h48
7:01 PM Indianapolis International Airport2 transfers
UnitedUA1858 · UA2331 · UA598510:13 AM Charleston International Airport
7h39
5:52 PM Indianapolis International Airport2 transfers
psa airlinesAA5216 · AA557611:07 AM Charleston International Airport
5h39
4:46 PM Indianapolis International Airport1 transfer
UnitedUA674 · UA1992 · UA358511:13 AM Charleston International Airport
8h03
7:16 PM Indianapolis International Airport2 transfers
UnitedUA674 · UA2788 · UA345511:13 AM Charleston International Airport
9h00
8:13 PM Indianapolis International Airport2 transfers
UnitedUA674 · UA344311:13 AM Charleston International Airport
6h53
6:06 PM Indianapolis International Airport1 transfer
UnitedUA592 · UA58711:31 AM Charleston International Airport
4h59
4:30 PM Indianapolis International Airport1 transfer
UnitedUA592 · UA598511:31 AM Charleston International Airport
6h21
5:52 PM Indianapolis International Airport1 transfer
Republic AirlinesAA4664 · AA445812:00 PM Charleston International Airport
7h59
7:59 PM Indianapolis International Airport1 transfer
American AirlinesAA1105 · AA241812:23 PM Charleston International Airport
7h15
7:38 PM Indianapolis International Airport1 transfer
American AirlinesAA1105+Republic AirlinesAA474012:23 PM Charleston International Airport
10h40
11:03 PM Indianapolis International Airport1 transfer
American AirlinesAA1105+Republic AirlinesAA441612:23 PM Charleston International Airport
11h35
11:58 PM Indianapolis International Airport1 transfer
American AirlinesAA1399+psa airlinesAA559112:25 PM Charleston International Airport
5h29
5:54 PM Indianapolis International Airport1 transfer
American AirlinesAA2839+psa airlinesAA5591+Republic AirlinesAA450112:25 PM Charleston International Airport
6h35
7:00 PM Indianapolis International Airport2 transfers
American AirlinesAA2447 · AA33191:12 PM Charleston International Airport
4h51
6:03 PM Indianapolis International Airport1 transfer
American AirlinesAA2447+Republic AirlinesAA46371:12 PM Charleston International Airport
7h44
8:56 PM Indianapolis International Airport1 transfer
psa airlinesAA5607+Republic AirlinesAA45011:58 PM Charleston International Airport
5h02
7:00 PM Indianapolis International Airport1 transfer
psa airlinesAA5607+Republic AirlinesAA45201:58 PM Charleston International Airport
7h32
9:30 PM Indianapolis International Airport1 transfer
American AirlinesAA3170 · AA13992:06 PM Charleston International Airport
3h48
5:54 PM Indianapolis International Airport1 transfer
UnitedUA3401 · UA35852:47 PM Charleston International Airport
4h29
7:16 PM Indianapolis International Airport1 transfer
UnitedUA3401 · UA2497 · UA36602:47 PM Charleston International Airport
8h57
11:44 PM Indianapolis International Airport2 transfers
UnitedUA3401 · UA2497 · UA37072:47 PM Charleston International Airport
7h18
10:05 PM Indianapolis International Airport2 transfers
UnitedUA3426 · UA34553:08 PM Charleston International Airport
5h05
8:13 PM Indianapolis International Airport1 transfer
UnitedUA3426 · UA2202 · UA40213:08 PM Charleston International Airport
8h51
11:59 PM Indianapolis International Airport2 transfers
American AirlinesAA2166 · AA7663:32 PM Charleston International Airport
8h11
11:43 PM Indianapolis International Airport1 transfer
UnitedUA2693 · UA37053:34 PM Charleston International Airport
6h41
10:15 PM Indianapolis International Airport1 transfer
UnitedUA2693 · UA2677 · UA40213:34 PM Charleston International Airport
8h25
11:59 PM Indianapolis International Airport2 transfers
UnitedUA2693 · UA35193:34 PM Charleston International Airport
5h23
8:57 PM Indianapolis International Airport1 transfer
Republic AirlinesAA4520+psa airlinesAA50904:08 PM Charleston International Airport
5h22
9:30 PM Indianapolis International Airport1 transfer
UnitedUA2757 · UA15224:16 PM Charleston International Airport
22h19
2:35 PM Indianapolis International Airport1 transfer
UnitedUA6329 · UA4655:00 PM Charleston International Airport
6h26
11:26 PM Indianapolis International Airport1 transfer
UnitedUA4322 · UA40217:46 PM Charleston International Airport
4h13
11:59 PM Indianapolis International Airport1 transfer
American AirlinesAA1586 · AA10337:48 PM Charleston International Airport
3h25
11:13 PM Indianapolis International Airport1 transfer

This is the last flight of the day.

Find all the dates and times for this journey

Why should you book Charleston, SC to Indianapolis, IN flights with Omio?

Republic Airlines as well as American Airlines offer flights services from Charleston, SC to Indianapolis, IN.
Omio is the only official third party seller for Republic Airlines tickets.

Why book with Omio vs Republic Airlines?

  • Compare with other providers: On Omio, you can not only buy tickets for Republic Airlines, but also compare tickets for the likes of American Airlines to find the best option for your trip from Charleston, SC to Indianapolis, IN.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Republic Airlines with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Charleston, SC to Indianapolis, IN.

Airlines: Republic Airlines, American Airlines from Charleston, SC to Indianapolis, INFind the best flights between Charleston, SC to Indianapolis, IN with Omio's travel partners Republic Airlines, American Airlines from $47. We can find you the best deals, schedules and tickets when comparing and booking the best trip.

American Airlines

About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average Duration
5h 26m
Cheapest Price
$155
American Airlines frequency
14 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
Entertaiment on board
Learn more about American Airlines

Republic Airlines

About
Republic Airways is a major regional airline in the United States, operating as a subsidiary of Republic Airways Holdings. It provides scheduled passenger service for American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express) using a fleet of Embraer 170 and 175 regional jets. Headquartered in Indianapolis, Indiana, Republic Airways operates over 900 daily flights to more than 80 cities across the U.S. and Canada. The company is known for its large fleet of Embraer E-Jets and its state-of-the-art training facilities. In April 2025, Republic Airways Holdings announced its acquisition of Mesa Air Group, which is expected to create the second-largest regional carrier in the U.S.
Luggage & cancellation policy
Average Duration
6h 58m
Cheapest Price
$1207
Republic Airlines frequency
8 a day
Luggage included
One carry-on bag (24 x 16 x 10) and one personal item
Additional luggage
Checked bags for a fee
Cancellation Policy
Tickets are non-refundable but may be cancelled for future flight credit minus applicable fees
Pregnant on board
Passengers can fly up to the end of their 36th week for single pregnancies and the end of their 32nd week for multiple pregnancies
Unaccompagned minor
Unaccompanied minor service is available for children ages 5-14. Must be booked directly with Republic Airlines
Amenities on board the airplane
USB plugs
Accessibility
Republic Airlines offers assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request these services in advance to ensure availability and proper arrangements.

Complete guide to Indianapolis, IN

Things to do in Indianapolis, IN

Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.

  • Must visit

The Children's Museum of Indianapolis

World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.

View on mapVisit website
  • Must visit

Indianapolis Museum of Art at Newfields

Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.

View on mapVisit website
  • Recommended

Benjamin Harrison Presidential Site

Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.

View on mapVisit website

United States Dollar ($)

Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.

Average meal costs

Budget
$10-$18 for fast food or a casual meal.
Mid-range
$20-$40 per person for a restaurant meal.
Fine dining
$60+ per person for upscale dining.
Coffee
$3-$6 for coffee or a cappuccino.

Tipping culture

Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.

FAQs: Charleston, SC to Indianapolis, IN Flight

Find answers to the most common questions about traveling from Charleston, SC to Indianapolis, IN by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

FAQs
Cheap plane tickets from Charleston, SC to Indianapolis, IN can start from as little as $47 when you book in advance. The average flight ticket price for Charleston, SC to Indianapolis, IN is $294 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Charleston, SC to Indianapolis, IN is 4h 12m to travel the 594 miles (957 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Charleston, SC to Indianapolis, IN leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Charleston, SC to Indianapolis, IN leaves at 10:10 PM.
There are 47 flights a day from Charleston, SC to Indianapolis, IN which require at least one change with Republic Airlines, American Airlines. Schedules can vary on holidays or weekends with fewer flights.
When taking a flight from Charleston, SC to Indianapolis, IN, you can count on Republic Airlines, American Airlines for the best way to get you to Indianapolis, IN. You can also check all possible airlines who offer a service between Charleston, SC and Indianapolis, IN and compare the amenities they offer before buying a plane ticket.
Flights from Charleston, SC to Indianapolis, IN generally leave from Charleston International Airport and arrive in Indianapolis International Airport.Charleston International Airport is 1 miles (2 km) away from Charleston, SC city centre and Indianapolis International Airport is 4 miles (8 km) from Indianapolis, IN city centre.
It's helpful to compare your options as there are 3 ways to travel between Charleston, SC and Indianapolis, IN including taking a bus, flight, and train.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular airports

Popular airports from Charleston, SC to Indianapolis, IN

Most Charleston, SC to Indianapolis, IN flights use the Charleston International Airport to Indianapolis International Airport airport pair. Use this guide to compare Charleston, SC and Indianapolis, IN airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.

Departure airports in Charleston
Arrival airports in Indianapolis

Which Charleston, SC airport do flights to Indianapolis, IN leave from?

Flights from Charleston, SC to Indianapolis, IN depart from Charleston International Airport. The airport is 1 miles (3 km) from Charleston, SC city centre at 5500 Intertiol Blvd, North Charleston, SC 29418, USA.
Charleston International Airport (CHS)5500 Intertiol Blvd, North Charleston, SC 29418, USAWifiShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeCar Rental
City-centre transport

Getting to Charleston International Airport from Charleston city centre

Charleston International Airport is 2 km from Charleston city centre. Public transport options include:

BusXp3 · 18m
Xp3 · 20m
11 · 1h 31m · $5 · every ~2 min

Charleston International Airport airport facilities and services

Charleston International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, and Car Rental.

Food and drink

Food options include: Restaurants are available, including Charleston Beer Works (casual dining) and Caviar & Bas (café), located in the main terminal.

Wi-Fi and ATMs

Free Wi-Fi available throughout the airport. ATMs are located in the main terminal.

Luggage and lost property

Lost and found is available at the station.

Parking, taxis and toilets

Available at Charleston International Airport: Parking, Taxis, WC.

Bike and car services

Available at Charleston International Airport: Car Rental.

Accessibility

Accessibility facilities are available at Charleston International Airport: Ramps, assistance.

Shops, hotels and contact

Nearby hotels include Hotels like the DoubleTree by Hilton within walking distance..

More about Charleston International Airport

More options for your journey from Charleston, SC to Indianapolis, IN

Here are some other resources that might have the information you need

Buses from Charleston, SC to Indianapolis, IN
Trains from Charleston, SC to Indianapolis, IN
More information on flights to Charleston, SC
More information on flights to Indianapolis, IN

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