Charleston, SC CHS to Indianapolis, IN IND flight with Republic Airlines

Fri, Nov 07
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Republic Airlines
American Airlines
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Republic Airlines
American Airlines
Vueling Airlines
easyJet
Ryanair
1,000+ travel companies
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Journey information

Overview: Charleston, SC to Indianapolis, IN flight

USAUSA
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Icon of flight
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
594 miles (957 km)
Average flight duration
3h 3m
Cheapest ticket price
$87 (€71)
Flights per day
28
Fastest flight
3h 54m
Cheapest month to travel
May
First flight
05:00
Last flight
20:43

Key Takeaways

Train Ticket Prices
  • Budget Options: Train tickets from Charleston, SC to Indianapolis, IN start from as low as $87 (€71) if booked well in advance.
  • Standard Fares: Typically, trains cost $301 (€245) depending on the train type and class.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

The cheapest and fastest flights from Charleston, SC to Indianapolis, IN

Showing times and prices for Nov 07

Cheapest price

$297

Average price

$297

Fastest journey

6 h 1 m

Average duration

6 h 1 m

Flights per day

1

Distance

957 km

Cheap tickets

The best way to find a cheap flight ticket from Charleston, SC to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Charleston, SC to Indianapolis, IN will cost around $297 if you buy it on the day, but the cheapest tickets can be found for only $297.

Fast flights

Of the 1 flights that leave Charleston, SC for Indianapolis, IN onFri, Nov 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Nov 07 the direct flights cover the 957 km distance in an average of 6 h 1 m but if you time it right, some flights will get you there in just 6 h 1 m .

On Fri, Nov 07 the longest flights will take 6 h 1 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Spirit Airlines
02:10PM6h01
Charleston, SC
08:11PMIndianapolis, IN
$2971One-way
0 transfers

Travel Information

Compare bus and flight for Charleston, SC to Indianapolis, IN

Omio recommends booking the flight as it is the most popular option from Charleston, SC to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from €95. For those with little time consider booking a flight which can get you there in 3h 3m. The ticket price range depends on the travel mode: a bus costs an average of €95, and a flight costs an average of €71.

Distance: 594 miles (957 km)

Compare flight with

Most popular
Flight
Bus

€245

Average price

€139

Average price

Cheapest

6h 3m

Average total duration

Fastest

3h 3m

Onboard

+

3h 0m

Additional time*

24h 42m

Average total duration

24h 12m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Live departures

Charleston, SC to Indianapolis, IN flight times

The table below shows live departures for Charleston, SC to Indianapolis, IN flights for tomorrow, Friday, November 7. You can also manually refresh the results below to see updated flight journeys.

Last updated at 9:18 PM
ProviderDepartsDurationArrivesTransfers
Tickets
spirit_airlines2:10 PM Charleston, SC
6h01
8:11 PM Indianapolis, IN0 transfersDirect

This is the last flight of the day.

Find all the dates and times for this journey

Compare prices and tickets Charleston, SC to Indianapolis, IN by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Nov 07
Sat
Nov 08
Sun
Nov 09
Mon
Nov 10
Tue
Nov 11
Wed
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Thu
Nov 13

Airlines: Republic Airlines, American Airlines from Charleston, SC to Indianapolis, INFind the best flights between Charleston, SC to Indianapolis, IN with Omio's travel partners Republic Airlines, American Airlines from $87 (€71). We can find you the best deals, schedules and tickets when comparing and booking the best trip.

American Airlines

About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average Duration
5h 56m
Cheapest Price
$212 (€173)
American Airlines frequency
12 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
Entertaiment on board

Republic Airlines

About
Republic Airways is a major regional airline in the United States, operating as a subsidiary of Republic Airways Holdings. It provides scheduled passenger service for American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express) using a fleet of Embraer 170 and 175 regional jets. Headquartered in Indianapolis, Indiana, Republic Airways operates over 900 daily flights to more than 80 cities across the U.S. and Canada. The company is known for its large fleet of Embraer E-Jets and its state-of-the-art training facilities. In April 2025, Republic Airways Holdings announced its acquisition of Mesa Air Group, which is expected to create the second-largest regional carrier in the U.S.
Luggage & cancellation policy
Average Duration
6h 58m
Cheapest Price
$1207 (€982)
Republic Airlines frequency
7 a day
Luggage included
One carry-on bag (24 x 16 x 10) and one personal item
Additional luggage
Checked bags for a fee
Cancellation Policy
Tickets are non-refundable but may be cancelled for future flight credit minus applicable fees
Pregnant on board
Passengers can fly up to the end of their 36th week for single pregnancies and the end of their 32nd week for multiple pregnancies
Unaccompagned minor
Unaccompanied minor service is available for children ages 5-14. Must be booked directly with Republic Airlines
Amenities on board the airplane
USB plugs
Accessibility
Republic Airlines offers assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request these services in advance to ensure availability and proper arrangements.

FAQs: Charleston, SC to Indianapolis, IN Flight

Find answers to the most common questions about traveling from Charleston, SC to Indianapolis, IN by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

FAQs
The earliest flight from Charleston, SC to Indianapolis, IN leaves at 5: 00AM. Plan your trip with the Journey Planner   from Omio.
The latest flight from Charleston, SC to Indianapolis, IN leaves at 8: 29PM.
There are 22 flights a day from Charleston, SC to Indianapolis, IN which require at least one change with Republic Airlines. Schedules can vary on holidays or weekends with fewer flights.
Take the Charleston, SC to Indianapolis, IN flight with Republic Airlines. However, it's always good to check out all possible airlines for the journey from Charleston, SC to Indianapolis, IN as there might be differences in the amenities they offer.
The cheapest month to travel from Charleston, SC to Indianapolis, IN by plane is July.
It's helpful to compare your options as there are 2 ways to travel from Charleston, SC to Indianapolis, IN including taking a bus or flight.
Since neither Charleston, SC nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of USA and USA. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The best events to attend in Indianapolis, IN include:
  • Indy 500, the iconic automobile race held annually on Memorial Day weekend, attracting racing fans from around the world
  • Indiana State Fair, a beloved summer tradition featuring agricultural exhibits, live entertainment, and delicious local food
  • Gen Con, one of the largest tabletop gaming conventions in North America, offering a vibrant atmosphere for gamers and enthusiasts alike.
The best holidays to experience in Indianapolis, IN include:
  • Independence Day, vibrant fireworks and festive parades celebrating American heritage
  • Labor Day, pleasant weather perfect for outdoor activities and local events
  • Thanksgiving, a time for family gatherings with a cozy atmosphere and fewer crowds.
The best seasons to visit Indianapolis, IN are Spring or Fall. The best weather to explore Indianapolis, IN is during April-May or September-October.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e. G. 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs).
Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you.
Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.

popular airports

Popular airports from Charleston, SC to Indianapolis, IN

Charleston
Indianapolis
The major airport for departures in Charleston is Charleston International Airport. Find all the information you need to know about services, amenities and connections at Charleston International Airport for your trip from Charleston to Indianapolis.
Amenities at airport
WifiWifi
ShoppingShopping
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
LoungeLounge
Lost and Found OfficeLost and Found Office
Car RentalCar Rental
information
ticketOfficeHours
Distance to city center
2 km
carConnection
Car connection
I-526, Exit 16
Wifi
Wifi
  • Free Wi-Fi available throughout the airport.
Shopping
Shopping
  • Shops include Hudson News and Tech on the Go, located in the main terminal.
Parking
Parking
  • Parking available; short-term parking located near the terminal, approximately 0.47€ ($0.50) per hour.
Dining
Dining
  • Restaurants are available, including Charleston Beer Works (casual dining) and Caviar & Bas (café), located in the main terminal.
Taxis
Taxis
  • Available outside the terminal.
Accessibility
Accessibility
  • Ramps, assistance
WC
WC
  • Available throughout the airport.
Hotel
Hotel
  • Hotels like the DoubleTree by Hilton within walking distance.
Lounge
Lounge
  • The Club CHS lounge available for travelers.
Lost and Found Office
Lost and Found Office
  • Lost and Found located in the main terminal near baggage claim.
Car Rental
Car Rental
  • Car rental services are available in the rental car pavilion near baggage claim.
Public transit options for Charleston International Airport
  • Bus Route 11, North Charleston Transit Center, 12 miles

Most popular flights from Charleston, SC

More options for your journey from Charleston, SC to Indianapolis, IN

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