Journey information
Overview: Charleston, SC to Indianapolis, IN flight
Flights from Charleston, SC to Indianapolis, IN depart on average 41 times per day, taking around 3h 3m. Cheap flight tickets for this journey start at $59 (€47) if you book in advance.
The earliest flight runs at 05:00, the last at 22:10. The fastest flight covers the 594 miles (957 km) distance in 5h 9m. May is the cheapest month to fly.
Distance 594 miles (957 km) |
Average flight duration 3h 3m |
Cheapest ticket price $59 (€47) |
Flights per day 41 |
Fastest flight 5h 9m |
Cheapest month to travel May |
First flight 05:00 |
Last flight 22:10 |
The cheapest and fastest flights from Charleston, SC to Indianapolis, IN
Cheapest price
$304
Average price
$304
Fastest journey
6 h 1 m
Average duration
6 h 1 m
Flights per day
1
Distance
957 km
The best way to find a cheap flight ticket from Charleston, SC to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charleston, SC to Indianapolis, IN will cost around $304 if you buy it on the day, but the cheapest tickets can be found for only $304.
Of the 1 flights that leave Charleston, SC for Indianapolis, IN onFri, Feb 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Feb 06 the direct flights cover the 957 km distance in an average of 6 h 1 m but if you time it right, some flights will get you there in just 6 h 1 m .
On Fri, Feb 06 the longest flights will take 6 h 1 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Charleston, SC to Indianapolis, IN
Omio recommends booking the flight as it is the most popular option from Charleston, SC to Indianapolis, IN among Omio's users. If you are prioritising price take the flight with prices starting from €47. For those with little time consider booking a flight which can get you there in 3h 3m. The ticket price range depends on the travel mode: a flight costs an average of €47, and a train costs an average of €270.
Distance: 594 miles (957 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
€138 Average price Cheapest | €147 Average price | €335 Average price |
6h 3m Average total duration Fastest 3h 3m Onboard + 3h 0m Additional time* | 23h 55m Average total duration 23h 25m Onboard + 30m Additional time* | 33h 18m Average total duration 32h 48m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Charleston, SC to Indianapolis, IN by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 06
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Feb 12
Why should you book Charleston, SC to Indianapolis, IN flights with Omio?
Why book with Omio vs American Airlines?
- Compare with other providers: On Omio, you can not only buy tickets for American Airlines, but also compare tickets for the likes of Republic Airlines to find the best option for your trip from Charleston, SC to Indianapolis, IN.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare American Airlines with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Charleston, SC to Indianapolis, IN.
Why book with Omio over Trip, Edreams or Skyscanner?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Charleston, SC to Indianapolis, IN.
Airlines: Republic Airlines, American Airlines from Charleston, SC to Indianapolis, INFind the best flights between Charleston, SC to Indianapolis, IN with Omio's travel partners Republic Airlines, American Airlines from $59 (€47). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
American Airlines
Republic Airlines
FAQs: Charleston, SC to Indianapolis, IN Flight
Find answers to the most common questions about traveling from Charleston, SC to Indianapolis, IN by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

- Indy 500, the iconic automobile race held annually on Memorial Day weekend, attracting racing fans from around the world
- Indiana State Fair, a beloved summer tradition featuring agricultural exhibits, live entertainment, and delicious local food
- Gen Con, one of the largest tabletop gaming conventions in North America, offering a vibrant atmosphere for gamers and enthusiasts alike.
- Independence Day, vibrant fireworks and festive parades celebrating American heritage
- Labor Day, pleasant weather perfect for outdoor activities and local events
- Thanksgiving, a time for family gatherings with a cozy atmosphere and fewer crowds.
popular airports
Popular airports from Charleston, SC to Indianapolis, IN
- Free Wi-Fi available throughout the airport.
- Shops include Hudson News and Tech on the Go, located in the main terminal.
- Parking available; short-term parking located near the terminal, approximately 0.47€ ($0.50) per hour.
- Restaurants are available, including Charleston Beer Works (casual dining) and Caviar & Bas (café), located in the main terminal.
- Available outside the terminal.
- Ramps, assistance
- Available throughout the airport.
- Hotels like the DoubleTree by Hilton within walking distance.
- The Club CHS lounge available for travelers.
- Lost and Found located in the main terminal near baggage claim.
- Car rental services are available in the rental car pavilion near baggage claim.
- Bus Route 11, North Charleston Transit Center, 12 miles
- Free Wi-Fi available throughout the airport.
- Shops in Civic Plaza, including Hudson News and Tech on the Go.
- Parking available with both short-term and long-term options, approximately 1.9€ ($2) per hour.
- Restaurants in Civic Plaza, including fast food and sit-down options like Chick-fil-A and Harry & Izzy's
- Available outside the terminal.
- Available throughout the airport.
- Hotels nearby, such as the Crowne Plaza Indiapolis Airport.
- Showers available in Delta Sky Club, access with membership or fee.
- Lounges include Delta Sky Club and United Club.
- Lost and Found located in the Guest Services Center.
- Car rental services available in the Ground Transportation Center, including Hertz and Avis
- IndyGo Route 8, Airport Stop, 13 km
Most popular flights from Charleston, SC
More options for your journey from Charleston, SC to Indianapolis, IN
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