The cheapest and fastest trains from Boston, MA to Florence, SC
Cheapest price
$441
Average price
$643
Fastest journey
16 h 5 m
Average duration
19 h 5 m
Trains per day
2
Distance
1182 km
The best way to find a cheap train ticket from Boston, MA to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Boston, MA to Florence, SC will cost around $643 if you buy it on the day, but the cheapest tickets can be found for only $441.
It's difficult to get from Boston, MA to Florence, SC without transferring at least once.




Boston, MA - Florence, SCCompare Amtrak, Amtrak Acela


Travel Information
Compare train and bus for Boston, MA to Florence, SC
Omio recommends booking the train as it is the most popular option from Boston, MA to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from €81. For those with little time consider booking a train which can get you there in 16h 1m. The ticket price range depends on the travel mode: a bus costs an average of €81, and a train costs an average of €114.
Distance: 734 miles (1182 km)
Compare train with
Most popular Train | Bus |
|---|---|
€219 Average price | €81 Average price Cheapest |
16h 31m Average total duration Fastest 16h 1m Onboard + 30m Additional time* | 18h 5m Average total duration 17h 35m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Boston, MA to Florence, SC train times
The table below shows live departures for Boston, MA to Florence, SC trains for today, Sunday, December 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:55 PM Boston, MA | 21h57 | 5:52 PM Florence, SC | 1 transfer | |
| Monday, December 22 | |||||
![]() | 11:05 AM Boston, MA | 16h05 | 3:10 AM Florence, SC | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Boston, MA to Florence, SC by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Dec 28
Why should you book Boston to Florence trains with Omio?
Amtrak as well as Amtrak Acela offer trains services from Boston to Florence. Omio is an official ticket reseller for all your travel options from Boston to Florence.
Why book with Omio vs Amtrak?
- Compare with other providers: On Omio, you can not only buy tickets for Amtrak, but also compare tickets for the likes of Amtrak Acela to find the best option for your trip from Boston to Florence.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are train and bus to ensure you get the best deal for traveling from Boston to Florence.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Amtrak tickets can be bought on Amtrak's website or third party sellers, Omio allows you to compare with the likes of Amtrak Acela to help you choose the right option for your journey from Boston to Florence.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Boston to Florence.
Journey information
Overview: Train from Boston, MA to Florence, SC
Trains from Boston, MA to Florence, SC run on average 5 times per day, taking around 16h 1m. Cheap train tickets for this journey start at $142 (€114) but you can travel from only $101 (€81) by bus.
The earliest train runs at 08:12, the last at 23:32. The fastest train covers the 734 miles (1182 km) distance in 17h 50m.
Distance 734 miles (1182 km) |
Average train duration 16h 1m |
Cheapest ticket price $142 (€114) |
Trains per day 5 |
Fastest train 17h 50m |
First train 08:12 |
Last train 23:32 |
Train companies: Amtrak, Amtrak Acela from Boston, MA to Florence, SC trainsAmtrak, Amtrak Acela trains will get you between Boston, MA and Florence, SC from $101 (€81). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
Amtrak Acela
FAQs: Trains from Boston, MA to Florence, SC
Find answers to the most common questions about traveling from Boston, MA to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Boston, MA to Florence, SC
- 5:00 AM - 11:00 PM Monday - Sunday
- Free
- The car park is open 24/7. Access via Atlantic Avenue.
- Legal Sea Foods
- Tavern in the Square
- Outside the main entrance.
- Elevators, restrooms.
- $0.50
- InterContinental Boston
- The Langham, Boston
- Boston Harbor Hotel
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for Amtrak services
- Hall 2: platforms 6-13 for MBTA Commuter Rail services
- Bus terminal located on the upper level.
- Subway: Red Line
- Bus: Several lines available
- Commuter Rail: Multiple lines
- 5:00 AM - 1:00 AM Monday - Sunday
- Free
- Parking is available nearby with several garages in the vicinity.
- Sorellina
- Atlantic Fish Company
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $0.50
- Copley Square Hotel
- The Westin Copley Place
- Fairmont Copley Plaza
- Located in the main hall
- Avis
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-3 for Amtrak and MBTA Commuter Rail
- Hall 2: Orange Line subway platforms
- Subway: Orange Line
- Bus: Several lines available
- Commuter Rail: Framingham/Worcester Line, Franklin Line, Needham Line, Providence/Stoughton Line
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Elevators, ramps.
- Aloft Florence
- Hyatt Place Florence Downtown
- Hotel Florence, Tapestry Collection by Hilton
- Located in the main hall
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Greyhound services available nearby
Most popular train connections from Boston, MA
More options for your journey from Boston, MA to Florence, SC
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