Travel Information
Compare train, bus, and flight for Frankfurt am Main to Lyon
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $30. For those with little time consider booking a flight which can get you there in 1h 57m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $30, and a flight costs an average of $171.
Distance: 349 miles (563 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$198 Average price | $55 Average price Cheapest | $400 Average price | $181 Average price (fuel + tolls) |
6h 36m Average total duration 6h 6m Onboard + 30m Additional time* | 10h 35m Average total duration 10h 5m Onboard + 30m Additional time* | 4h 57m Average total duration Fastest 1h 57m Onboard + 3h 0m Additional time* | 7h 16m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Lyon:
A bus is $142 (€115) less than a train for this route with tickets for a train from Frankfurt am Main to Lyon costing on average $198 (€159).
A bus is $345 (€277) less than a flight for this route with tickets for a flight from Frankfurt am Main to Lyon costing on average $400 (€322).
Other travel options to Lyon take longer:
Train takes on average 6h 6m.
Bus takes on average 10h 5m.
Travel optionsfrom Frankfurt am Main to Lyon
How to get from Frankfurt am Main to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Lyon is by taking a bus because it’s the best combination of price and speed.
Normal9:30 AM11h10Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)8:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$301One-way0 transfers
Cheapest
Normal9:30 AM11h10Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)8:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$301One-way0 transfers
Fastest
LH108210:10 PM1h20Frankfurt am Main Airport11:30 PMLyon Saint Exupery Airport$4751One-way0 transfers
Other options
ICE 9514+
TGV 958012:53 PM7h05Frankfurt (Main) Hbf7:58 PMLyon Part Dieu$1491One-way1 transfer
ICE 9514+
553912:53 PM10h03Frankfurt (Main) Hbf10:56 PMLyon Part Dieu$1911One-way1 transfer
ICE 71+
12177+
TGV 957410:20 AM7h39Frankfurt (Main) Hbf5:59 PMLyon Part Dieu$2141One-way2 transfers
Normal8:55 AM11h45Frankfurt am Main, Mannheimer Straße (Hauptbahnhof)8:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$301One-way0 transfers
515106:30 PM10h40Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)5:10 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$621One-way0 transfers
541538:55 AM11h50Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)8:45 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$621One-way0 transfers
12512+
AF10197:05 AM4h55Frankfurt am Main Airport12:00 PMLyon Part Dieu$2691One-way1 transfer
9812+
AF10197:05 AM4h55Frankfurt am Main Airport12:00 PMLyon Part Dieu$2811One-way1 transfer
AF7368+
AF161912:10 PM5h40Frankfurt am Main Airport5:50 PMLyon Saint Exupery Airport$2841One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Frankfurt am Main to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Lyon.

This is compared to other travel options from Frankfurt am Main to Lyon:
A bus is $142 (€115) less than a train for this route with tickets for a train from Frankfurt am Main to Lyon costing on average $198 (€159).
A bus is $345 (€277) less than a flight for this route with tickets for a flight from Frankfurt am Main to Lyon costing on average $400 (€322).
Other travel options to Lyon take longer:
Train takes on average 6h 6m.
Bus takes on average 10h 5m.
- Around 12 flights per day.
- Around 12 buses per day.
- Around 4 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) and arrive in Lyon, Perrache Bus Station.
- Travel with FlixBus, BlaBlaCar Bus, Infobus, Sindbad, BlaBlaCar to go to Lyon by bus.
- Travel with Lufthansa, Air Dolomiti, KLM, KLM Cityhopper, Lufthansa Cityline, Brussels Airlines to go to Lyon by flight.
- Travel with TGV, SNCF | TGV INOUI, ÖBB | ICE, Deutsche Bahn Intercity (DB IC) to go to Lyon by train.
- 5 direct buses per day with FlixBus, BlaBlaCar Bus, Infobus, Sindbad, BlaBlaCar.
- 4 direct flights per day with Lufthansa, Air Dolomiti.
- 1 direct trains per day with TGV, SNCF | TGV INOUI.
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