Travel Information
Compare train, bus, and flight for Frankfurt am Main to Lyon
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $64 For those with little time, consider booking a flight, which has an average total journey time of 4h 48m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $64, while a flight costs an average of $482.
Distance: 349 miles (563 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$85 Average price | $64 Average price Cheapest | $482 Average price | $174 Average price (fuel + tolls) |
6h 36m Average total duration 6h 6m Onboard + 30m Additional time* | 11h 38m Average total duration 11h 8m Onboard + 30m Additional time* | 4h 48m Average total duration Fastest 2h 48m Onboard + 2h 0m Additional time* | 7h 16m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Lyon:
A bus is $21 (€18) less than a train for this route with tickets for a train from Frankfurt am Main to Lyon costing on average $85 (€71).
A bus is $418 (€352) less than a flight for this route with tickets for a flight from Frankfurt am Main to Lyon costing on average $482 (€405).
Other travel options to Lyon take longer:
Train takes on average 6h 36m.
Bus takes on average 11h 38m.
The journey is about 1h 10m faster (6h 6m by train vs 7h 16m by car) and roughly $89 (€75) cheaper once you factor in fuel and tolls ($85 (€71) vs $174 (€146)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Frankfurt am Main to Lyon
How to get from Frankfurt am Main to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Lyon is by taking a bus because it’s the best combination of price and speed.
07:30 AM10h15Frankfurt am Main5:45 PMLyon$371One-way0 transfers
Cheapest
07:30 AM10h15Frankfurt am Main5:45 PMLyon$371One-way0 transfers
Fastest
LH107612:30 PM1h20Frankfurt am Main Airport1:50 PMLyon Saint Exupery Airport$4541One-way0 transfers
Other options
FlixBus+
FlixTrain2:03 PM14h17Frankfurt South station4:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$511One-way1 transfer
FlixBus8:15 AM12h35Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)8:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$511One-way0 transfers
FlixBus7:05 PM10h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)5:05 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$571One-way0 transfers
AF1519 · AF73669:45 AM4h00Frankfurt am Main Airport1:45 PMLyon Saint Exupery Airport$2711One-way1 transfer
AF1619 · AF736812:10 PM6h00Frankfurt am Main Airport6:10 PMLyon Saint Exupery Airport$2711One-way1 transfer
AF1019 · AF73667:05 AM6h40Frankfurt am Main Airport1:45 PMLyon Saint Exupery Airport$2711One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Frankfurt am Main to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Lyon.

This is compared to other travel options from Frankfurt am Main to Lyon:
A bus is $21 (€18) less than a train for this route with tickets for a train from Frankfurt am Main to Lyon costing on average $85 (€71).
A bus is $418 (€352) less than a flight for this route with tickets for a flight from Frankfurt am Main to Lyon costing on average $482 (€405).
Other travel options to Lyon take longer:
Train takes on average 6h 36m.
Bus takes on average 11h 38m.
- Around 18 flights per day.
- Around 16 trains per day.
- Around 12 buses per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with FlixBus, BlaBlaCar Bus, Alsa, Sindbad to go to Lyon by bus.
- Travel with Lufthansa, Air Dolomiti, Lufthansa Cityline, KLM, BA Euroflyer, KLM Cityhopper, Brussels Airlines, Air Baltic, Helvetic Airways, Lot Polish Airlines, British Airways, Lufthansa City Airlines, Air France, Austrian Airlines, Bulgaria Air to go to Lyon by flight.
- Travel with TGV, SNCF | TGV INOUI, SNCF | Intercités, SNCF TER | Operated by SNCF Voyageurs 1187, SNCF | Intercités de nuit, TER, Deutsche Bahn to go to Lyon by train.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus, Alsa, Sindbad.
- 4 direct flights per day with Lufthansa, Air Dolomiti.
- 1 direct trains per day with TGV, SNCF | TGV INOUI.
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