Travel Information
Compare train, bus, and flight for Düsseldorf to Lyon
Omio recommends booking the bus as it is the most popular option from Düsseldorf to Lyon among Omio's users. If you are prioritising price, take the train, with an average ticket price of $72 For those with little time, consider booking a flight, which has an average total journey time of 4h 39m. Average ticket prices depend on the travel mode: a train costs an average of $72, while a flight costs an average of $488.
Distance: 388 miles (625 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$77 Average price | $488 Average price | $72 Average price Cheapest | $187 Average price (fuel + tolls) |
14h 49m Average total duration 14h 19m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 2h 39m Onboard + 2h 0m Additional time* | 7h 1m Average total duration 6h 31m Onboard + 30m Additional time* | 8h 29m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Düsseldorf to Lyon:
A train is $5 (€4) less than a bus for this route with tickets for a bus from Düsseldorf to Lyon costing on average $77 (€65).
A train is $416 (€349) less than a flight for this route with tickets for a flight from Düsseldorf to Lyon costing on average $488 (€410).
Other travel options to Lyon take longer:
Train takes on average 7h 1m.
Bus takes on average 14h 49m.
Tickets start at around $77 (€65) compared to roughly $187 (€157) in fuel and tolls — a saving of about $109 (€92). The journey takes 14h 19m versus 8h 29m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Düsseldorf to Lyon
How to get from Düsseldorf to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Düsseldorf to Lyon is by taking a bus because it’s the best combination of price and speed.
50449 · 51319:45 PM21h05Düsseldorf, ZOB am Hbf6:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$551One-way1 transfer
Cheapest
50449 · 51319:45 PM21h05Düsseldorf, ZOB am Hbf6:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$551One-way1 transfer
Fastest
AF1307+
125269:25 AM4h35Dusseldorf Airport2:00 PMLyon Part Dieu$12361One-way1 transfer
Other options
9426+
66197:58 AM8h58Düsseldorf Hbf4:56 PMLyon Part Dieu$2371One-way1 transfer
9426+
177777:58 AM12h46Düsseldorf Hbf8:44 PMLyon Part Dieu$2631One-way1 transfer
9426+
177797:58 AM14h46Düsseldorf Hbf10:44 PMLyon Part Dieu$2631One-way1 transfer
FlixBus11:00 PM10h45Düsseldorf, ZOB am Hbf9:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$601One-way0 transfers
FlixBus · FlixBus5:25 PM14h50Düsseldorf, ZOB am Hbf8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$651One-way1 transfer
FlixBus · FlixBus2:25 PM14h40Düsseldorf, ZOB am Hbf5:05 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$831One-way1 transfer
KL1796 · KL1405+
125266:25 AM7h35Dusseldorf Airport2:00 PMLyon Part Dieu$4121One-way2 transfers
KL1796 · KL1407+
51246:25 AM15h34Dusseldorf Airport9:59 PMLyon Part Dieu$4121One-way2 transfers
KL1800 · KL1409+
512412:25 PM9h34Dusseldorf Airport9:59 PMLyon Part Dieu$4131One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Düsseldorf to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Düsseldorf to Lyon.

This is compared to other travel options from Düsseldorf to Lyon:
A train is $5 (€4) less than a bus for this route with tickets for a bus from Düsseldorf to Lyon costing on average $77 (€65).
A train is $416 (€349) less than a flight for this route with tickets for a flight from Düsseldorf to Lyon costing on average $488 (€410).
Other travel options to Lyon take longer:
Train takes on average 7h 1m.
Bus takes on average 14h 49m.
- Around 23 flights per day.
- Around 6 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Düsseldorf and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Dusseldorf Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Düsseldorf Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Düsseldorf, ZOB am Hbf and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with TGV, Eurostar, SNCF | TGV INOUI, TER to go to Lyon by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Lyon by bus.
- Travel with Lufthansa, Eurowings, Air Dolomiti, Lufthansa Cityline, Vueling, Air Baltic, Air France, KLM, Avion Express Malta, BA Euroflyer, KLM Cityhopper, Brussels Airlines, Lufthansa City Airlines, Austrian Airlines, Helvetic Airways, British Airways to go to Lyon by flight.
- 1 direct buses per day with FlixBus.
- 0 direct flights per day with Eurowings, Avion Express Malta.
Travelling from Düsseldorf to Lyon: related information
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