Travel Information
Compare train, bus, and flight for Düsseldorf to Lyon
Omio recommends booking the bus as it is the most popular option from Düsseldorf to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $39. For those with little time consider booking a flight which can get you there in 2h 20m. The ticket price range depends on the travel mode: a bus costs an average of $39, and a flight costs an average of $92.
Distance: 388 miles (625 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$68 Average price Cheapest | $239 Average price | $255 Average price |
12h 43m Average total duration 12h 13m Onboard + 30m Additional time* | 6h 57m Average total duration 6h 27m Onboard + 30m Additional time* | 5h 20m Average total duration Fastest 2h 20m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Düsseldorf to Lyon
How to get from Düsseldorf to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Düsseldorf to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus5:50 PM16h40Düsseldorf, ZOB am Hbf10:30 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$891One-way1 transfer
Cheapest
FlixBus · FlixBus6:20 PM18h30Düsseldorf, ZOB am Hbf12:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$881One-way1 transfer
Fastest
EW94167:00 PM1h25Dusseldorf Airport8:25 PMLyon Saint Exupery Airport$6911One-way0 transfers
Other options
9414+
66136:09 AM7h47Düsseldorf Hbf1:56 PMLyon Part Dieu$3011One-way1 transfer
9414+
66136:09 AM8h01Düsseldorf Hbf2:10 PMGare de Lyon-Perrache$3011One-way1 transfer
9426+
66178:10 AM7h46Düsseldorf Hbf3:56 PMLyon Part Dieu$3831One-way1 transfer
FlixBus · FlixBus7:15 AM16h00Düsseldorf, ZOB am Hbf11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$881One-way1 transfer
FlixBus · FlixBus2:25 PM17h50Düsseldorf, ZOB am Hbf8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$881One-way1 transfer
FlixBus · FlixBus1:45 PM15h00Düsseldorf, ZOB am Hbf4:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$951One-way1 transfer
VY1899 · VY12209:00 PM12h05Dusseldorf Airport9:05 AMLyon Saint Exupery Airport$6241One-way1 transfer
KL1802+
KL14272:30 PM18h55Dusseldorf Airport9:25 AMLyon Saint Exupery Airport$7541One-way1 transfer
QS8041 · QS1034+
51246:35 AM15h25Dusseldorf Airport10:00 PMLyon Part Dieu$8291One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 15
Apr 16
Apr 17
Apr 18
Apr 19
Apr 20
Apr 21
Apr 22
Apr 23
Apr 24
Apr 25
Apr 26
Apr 27
Apr 28
Apr 29
Apr 30
May 01
May 02
May 03
May 04
May 05
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Düsseldorf to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Düsseldorf to Lyon.

This is compared to other travel options from Düsseldorf to Lyon:
A bus is $16 (€12) less than a train for this route with tickets for a train from Düsseldorf to Lyon costing on average $55 (€43).
A bus is $54 (€43) less than a flight for this route with tickets for a flight from Düsseldorf to Lyon costing on average $92 (€74).
Other travel options to Lyon take longer:
Train takes on average 6h 46m.
Bus takes on average 10h 45m.
- Around 14 flights per day.
- Around 6 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Düsseldorf and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Dusseldorf Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Düsseldorf Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Düsseldorf, ZOB am Hbf and arrive in Lyon, Perrache Bus Station.
- Travel with Eurowings, Lufthansa, Lufthansa Cityline, Air Dolomiti, Air Baltic, KLM, Vueling Airlines, Air France to go to Lyon by flight.
- Travel with TGV, TGV INOUI, Deutsche Bahn to go to Lyon by train.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar to go to Lyon by bus.
- 1 direct buses per day with FlixBus, BlaBlaCar.
Travelling from Düsseldorf to Lyon: related information
Here are some other resources that might have the information you need


