4.9
4.6
Travel Information
Compare train, bus, and flight for Prague to Lyon
Omio recommends booking the bus as it is the most popular option from Prague to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €70 For those with little time, consider booking a flight, which has an average total journey time of 4h 39m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.9 - 2.1kg. Average ticket prices depend on the travel mode: a bus costs an average of €70, while a train costs an average of €239.
Distance: 534 miles (860 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
€70 Average price Cheapest | €172 Average price | €239 Average price | €218 Average price (fuel + tolls) |
17h 4m Average total duration 16h 34m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 2h 39m Onboard + 2h 0m Additional time* | 14h 30m Average total duration 14h 0m Onboard + 30m Additional time* | 9h 53m Average total duration (door-to-door) |
0.9 - 2.1kg CO2 emissions Lowest | 2.6 - 5.2kg CO2 emissions | - CO2 emissions | - CO2 emissions |
 Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Lyon:
A bus is €102 less than a flight for this route with tickets for a flight from Prague to Lyon costing on average €172.
A bus is €168 less than a train for this route with tickets for a train from Prague to Lyon costing on average €239.
Other travel options to Lyon take longer:
Train takes on average 14h 30m.
Bus takes on average 17h 4m.
Tickets start at around €70 compared to roughly €218 in fuel and tolls — a saving of about €148. The journey takes 16h 34m versus 9h 53m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Prague to Lyon
How to get from Prague to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Prague to Lyon is by taking a bus because it’s the best combination of price and speed.
(Prague -> Lyon)11:00 PM15h50Praha, ÚAN Florenc2:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€601One-way0 transfers
Cheapest
- (Prague -> Lyon)11:00 PM15h50Praha, ÚAN Florenc2:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€601One-way0 transfers
Fastest
SN2812+
SN35936:45 PM3h35Prague Vaclav Havel Airport10:20 PMLyon Saint Exupery Airport€3411One-way1 transfer
Other options
- EX 362 · ICE 518+
TGV 95805:35 AM14h23Prague hlavní nádraží7:58 PMLyon Part Dieu€2261One-way2 transfers - RJ 384 · IC 2048 · ICE 597+TGV 95806:31 AM13h27Prague hlavní nádraží7:58 PMLyon Part Dieu€2601One-way3 transfers
- FlixBus9:50 PM14h50Praha, Na Knížecí12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€671One-way0 transfers
- FlixBus9:25 PM15h15Praha, ÚAN Florenc12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€671One-way0 transfers
- FlixBus4:15 PM16h50Prague, Central Train Station9:05 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€671One-way0 transfers
AF1583 · AF73666:30 AM7h15Prague Vaclav Havel Airport1:45 PMLyon Saint Exupery Airport€1971One-way1 transfer- AF1183 · AF73703:50 PM6h10Prague Vaclav Havel Airport10:00 PMLyon Saint Exupery Airport€2151One-way1 transfer
QS1034+
984412:20 PM9h39Prague Vaclav Havel Airport9:59 PMLyon Part Dieu€2361One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 16
Sep 17
Sep 18
Sep 19
Sep 20
Sep 21
Sep 22
Sep 23
Sep 24
Sep 25
Sep 26
Sep 27
Sep 28
Sep 29
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Prague to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Lyon.
This is compared to other travel options from Prague to Lyon:
A bus is €102 less than a flight for this route with tickets for a flight from Prague to Lyon costing on average €172.
A bus is €168 less than a train for this route with tickets for a train from Prague to Lyon costing on average €239.
Other travel options to Lyon take longer:
Train takes on average 14h 30m.
Bus takes on average 17h 4m.
- Around 43 flights per day.
- Around 13 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Lyon Part Dieu.
- Buses mostly depart from Prague, Central Train Station and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with Deutsche Bahn, ÖBB | Euro City (EC) to go to Lyon by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Lyon by bus.
- Travel with Volotea, easyJet, Lufthansa, Brussels Airlines, Austrian Airlines, Air France, Air Dolomiti, KLM, Lufthansa Cityline, Lot Polish Airlines, KLM Cityhopper, Vueling, Air Baltic to go to Lyon by flight.
- 6 direct buses per day with FlixBus.
- 1 direct flights per day with Volotea, easyJet.
Travelling from Prague to Lyon: related information
Here are some other resources that might have the information you need
Travel to popular destinations by train, bus or flight
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
