4.9
4.6
Travel Information
Compare train, bus, and flight for Prague to Lyon
Omio recommends booking the bus as it is the most popular option from Prague to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $89 For those with little time, consider booking a flight, which has an average total journey time of 5h 30m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.9 - 2.1kg. Average ticket prices depend on the travel mode: a bus costs an average of $89, while a flight costs an average of $512.
Distance: 534 miles (860 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$89 Average price Cheapest | $512 Average price | $297 Average price | $260 Average price (fuel + tolls) |
17h 22m Average total duration 16h 52m Onboard + 30m Additional time* | 5h 30m Average total duration Fastest 3h 30m Onboard + 2h 0m Additional time* | 13h 34m Average total duration 13h 4m Onboard + 30m Additional time* | 9h 53m Average total duration (door-to-door) |
0.9 - 2.1kg CO2 emissions Lowest | 2.6 - 5.2kg CO2 emissions | - CO2 emissions | - CO2 emissions |
 Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Prague to Lyon
Compare the available ways to get from Prague to Lyon, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Prague to Lyon:
A bus is $209 (€175) less than a train for this route with tickets for a train from Prague to Lyon costing on average $297 (€249).
A bus is $423 (€355) less than a flight for this route with tickets for a flight from Prague to Lyon costing on average $512 (€429).
Other travel options to Lyon take longer:
Train takes on average 13h 34m.
Bus takes on average 17h 22m.
Tickets start at around $89 (€75) compared to roughly $260 (€218) in fuel and tolls — a saving of about $172 (€144). The journey takes 16h 52m versus 9h 53m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Prague to Lyon
How to get from Prague to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Prague to Lyon is by taking a bus because it’s the best combination of price and speed.
- FlixBus
9:50 PM 14h50 Praha, Na Knížecí 12:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $92 1 One-way 0 transfers
Cheapest
- FlixBus
9:50 PM 14h50 Praha, Na Knížecí 12:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $92 1 One-way 0 transfers
Fastest
LH1397+
4Y6122:50 PM 3h30 Prague Vaclav Havel Airport 6:20 PM Lyon Saint Exupery Airport $406 1 One-way 1 transfer
Other options
EX 362 · Bus RE25 · 3562 · IC 21625:35 AM 14h23 Prague hlavní nádraží 7:58 PM Lyon Part Dieu $270 1 One-way 4 transfers
- FlixBus
9:25 PM 15h15 Praha, ÚAN Florenc 12:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $92 1 One-way 0 transfers - FlixBus · FlixBus · FlixBus
8:25 PM 18h55 Praha, Zličín 3:20 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $133 1 One-way 2 transfers 
30513 · 517087:00 PM 21h25 Praha, ÚAN Florenc 4:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $135 1 One-way 1 transfer
- LO526 · LO345
7:40 PM 14h50 Prague Vaclav Havel Airport 10:30 AM Lyon Saint Exupery Airport $219 1 One-way 1 transfer - LO522 · LO345
6:00 PM 16h30 Prague Vaclav Havel Airport 10:30 AM Lyon Saint Exupery Airport $219 1 One-way 1 transfer 
KL1360 · KL14278:20 PM 12h40 Prague Vaclav Havel Airport 9:00 AM Lyon Saint Exupery Airport $264 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Prague to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Lyon.
This is compared to other travel options from Prague to Lyon:
A bus is $209 (€175) less than a train for this route with tickets for a train from Prague to Lyon costing on average $297 (€249).
A bus is $423 (€355) less than a flight for this route with tickets for a flight from Prague to Lyon costing on average $512 (€429).
Other travel options to Lyon take longer:
Train takes on average 13h 34m.
Bus takes on average 17h 22m.
- Around 46 flights per day.
- Around 15 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Lyon Part Dieu.
- Buses mostly depart from Prague, Central Train Station and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with FlixBus, BlaBlaCar Bus, AMI-Tour, Infobus to go to Lyon by bus.
- Travel with TGV, Deutsche Bahn to go to Lyon by train.
- Travel with Lot Polish Airlines, Lufthansa, KLM, Air France, Brussels Airlines, Austrian Airlines, British Airways, Turkish Airlines, Air Baltic, Lufthansa Cityline, KLM Cityhopper, Vueling, Air Dolomiti, Buzz, easyJet, Lufthansa City Airlines, Volotea, Swiss, Helvetic Airways, Eurowings, Ryanair, CitizenPlane, Edelweiss Air to go to Lyon by flight.
- 6 direct buses per day with FlixBus, AMI-Tour, Infobus.
- 1 direct flights per day with easyJet, Volotea, CitizenPlane.
Travelling from Prague to Lyon: related information
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