Travel Information
Compare train, bus, and flight for Prague to Lyon
Omio recommends booking the flight as it is the most popular option from Prague to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $57. For those with little time consider booking a flight which can get you there in 2h 42m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $57, and a train costs an average of $276.
Distance: 534 miles (860 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$188 Average price | $86 Average price Cheapest | $313 Average price |
5h 42m Average total duration Fastest 2h 42m Onboard + 3h 0m Additional time* | 17h 2m Average total duration 16h 32m Onboard + 30m Additional time* | 14h 30m Average total duration 14h 0m Onboard + 30m Additional time* |
2.6 - 5.2kg CO2 emissions | 0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Lyon
How to get from Prague to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Prague to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus3:10 PM17h05Praha, ÚAN Florenc8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1001One-way0 transfers
Cheapest
FlixBus3:10 PM17h05Praha, ÚAN Florenc8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1001One-way0 transfers
Fastest
SN2812+
SN35936:45 PM3h35Prague Vaclav Havel Airport10:20 PMLyon Saint Exupery Airport$9441One-way1 transfer
Other options
RJ 384 · IC 2048 · ICE 597+
TGV 95806:31 AM13h27Prague hlavní nádraží7:58 PMLyon Part Dieu$3711One-way3 transfers
FlixBus2:30 PM17h45Praha, Černý Most8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1001One-way0 transfers
FlixBus6:40 AM16h35Praha, ÚAN Florenc11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1031One-way0 transfers
FlixBus · FlixBus5:45 PM21h00Praha, Na Knížecí2:45 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1021One-way1 transfer
QS1034+
512412:20 PM9h40Prague Vaclav Havel Airport10:00 PMLyon Part Dieu$2021One-way1 transfer
QS1034+
983612:20 PM7h42Prague Vaclav Havel Airport8:02 PMLyon Part Dieu$2191One-way1 transfer
QS1034+
1253612:20 PM7h42Prague Vaclav Havel Airport8:02 PMLyon Part Dieu$2251One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Prague to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Lyon.

This is compared to other travel options from Prague to Lyon:
A flight is $5 (€4) less than a bus for this route with tickets for a bus from Prague to Lyon costing on average $57 (€46).
A flight is $223 (€179) less than a train for this route with tickets for a train from Prague to Lyon costing on average $276 (€221).
Other travel options to Lyon take longer:
Train takes on average 13h 27m.
Bus takes on average 14h 35m.
- Around 38 flights per day.
- Around 12 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Trains mostly depart from Prague hlavní nádraží and arrive in Lyon Part Dieu.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Lyon Saint Exupery Airport.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Lyon, Perrache Bus Station.
- Travel with Volotea, easyJet, Lufthansa, Brussels Airlines, Air France, Air Dolomiti, Lufthansa Cityline, Austrian Airlines, KLM, KLM Cityhopper, Vueling, Air Baltic, Lot Polish Airlines to go to Lyon by flight.
- Travel with Deutsche Bahn, ÖBB | Euro City (EC) to go to Lyon by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Lyon by bus.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus.
Travelling from Prague to Lyon: related information
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