Travel Information
Compare bus, flight, and train for Florence to Lyon
Omio recommends booking the bus as it is the most popular option from Florence to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $19. For those with little time consider booking a flight which can get you there in 3h 17m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.4kg. The ticket price range depends on the travel mode: a bus costs an average of $19, and a flight costs an average of $44.
Distance: 342 miles (551 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$46 Average price Cheapest | $153 Average price | $231 Average price |
14h 9m Average total duration 13h 39m Onboard + 30m Additional time* | 8h 53m Average total duration 8h 23m Onboard + 30m Additional time* | 6h 17m Average total duration Fastest 3h 17m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions Lowest | - CO2 emissions | 1.7 - 3.3kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Florence to Lyon:
A bus is $107 (€86) less than a train for this route with tickets for a train from Florence to Lyon costing on average $153 (€123).
A bus is $185 (€149) less than a flight for this route with tickets for a flight from Florence to Lyon costing on average $231 (€187).
Other travel options to Lyon take longer:
Train takes on average 8h 23m.
Bus takes on average 13h 39m.
Travel optionsfrom Florence to Lyon
How to get from Florence to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Florence to Lyon is by taking a bus because it’s the best combination of price and speed.
38981:05 AM11h50Scandicci, Villa Costanza (Florence)12:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$501One-way0 transfers
Cheapest
38981:05 AM11h50Scandicci, Villa Costanza (Florence)12:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$501One-way0 transfers
Fastest
LH2250+
LH94391:20 PM3h45Florence Peretola Airport5:05 PMLyon Saint Exupery Airport$3121One-way1 transfer
Other options
Regionale 18508 · Regionale TTPER 17906 · Regionale Veloce TTPER 2470+
FRECCIAROSSA 1000 92969:09 AM11h23Florence Santa Maria Novella8:32 PMLyon Part Dieu$1361One-way3 transfers
Regionale 1792 · Regionale Veloce TTPER 2466+
FRECCIAROSSA 1000 92967:17 AM13h15Florence Santa Maria Novella8:32 PMLyon Part Dieu$1361One-way2 transfers
Regionale 17800 · Regionale Veloce TTPER 2460+
FRECCIAROSSA 1000 92964:32 AM16h00Florence Santa Maria Novella8:32 PMLyon Part Dieu$1361One-way2 transfers
2126 · 309211:55 AM12h30Scandicci, Villa Costanza (Florence)12:25 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$681One-way1 transfer
349210:20 AM11h10Scandicci, Villa Costanza (Florence)9:30 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$781One-way0 transfers
FlixBus7:30 AM10h40Scandicci, Villa Costanza (Florence)6:10 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$831One-way0 transfers
AF1267 · AF73646:40 AM3h50Florence Peretola Airport10:30 AMLyon Saint Exupery Airport$2321One-way1 transfer
AF1067 · AF73669:50 AM3h55Florence Peretola Airport1:45 PMLyon Saint Exupery Airport$2321One-way1 transfer
AF1567 · AF73703:20 PM6h05Florence Peretola Airport9:25 PMLyon Saint Exupery Airport$2321One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Florence to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Florence to Lyon.

This is compared to other travel options from Florence to Lyon:
A bus is $107 (€86) less than a train for this route with tickets for a train from Florence to Lyon costing on average $153 (€123).
A bus is $185 (€149) less than a flight for this route with tickets for a flight from Florence to Lyon costing on average $231 (€187).
Other travel options to Lyon take longer:
Train takes on average 8h 23m.
Bus takes on average 13h 39m.
- Around 25 flights per day.
- Around 16 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Florence and Lyon as scheduled services by bus, flight, and train can vary by season or day of the week.
- Flights mostly depart from Florence Peretola Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Florence Santa Maria Novella and arrive in Lyon Part Dieu.
- Buses mostly depart from Scandicci, Villa Costanza (Florence) and arrive in Lyon, Perrache Bus Station.
- Travel with FlixBus, Itabus, BlaBlaCar Bus, BlaBlaCar, Gruppo Di Maio to go to Lyon by bus.
- Travel with Volotea, Air France, Vueling, Lufthansa, Air Dolomiti, Lufthansa Cityline, KLM Cityhopper to go to Lyon by flight.
- Travel with Trenitalia, Frecciarossa, Intercity Notte, SNCF | TGV INOUI, Regionale, Intercity to go to Lyon by train.
- 7 direct buses per day with FlixBus, Itabus, BlaBlaCar Bus, BlaBlaCar.
Travelling from Florence to Lyon: related information
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