Travel Information
Compare train, bus, and flight for Pisa to Madrid
Omio recommends booking the flight as it is the most popular option from Pisa to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from $53. For those with little time consider booking a flight which can get you there in 3h 38m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.0kg. The ticket price range depends on the travel mode: a bus costs an average of $53, and a train costs an average of $344.
Distance: 757 miles (1219 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$183 Average price | $172 Average price Cheapest | $344 Average price |
6h 38m Average total duration Fastest 3h 38m Onboard + 3h 0m Additional time* | 23h 19m Average total duration 22h 49m Onboard + 30m Additional time* | 29h 6m Average total duration 28h 36m Onboard + 30m Additional time* |
3.7 - 7.3kg CO2 emissions | 1.2 - 3.0kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Pisa to Madrid
How to get from Pisa to Madrid by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Madrid is by taking a flight because it’s the best combination of price and speed.
ETRUSCHI LINE 4131 · Regionale 20495+
IB656Cheapest
InterCityNotte 899+
Regionale 20391+
IB660Fastest
FRECCIARGENTO 8551+
Leonardo express 4576+
IB652Other options
Intercity 505+
Regionale 20485+
IB656
InterCityNotte 899+
Regionale 20391+
UX1040
Intercity 501+
Regionale 20449+
IB650Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 25
Feb 26
Feb 27
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Pisa to Madrid
Travel to Madrid easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Madrid.

This is compared to other travel options from Pisa to Madrid:
A flight is $13 (€10) less than a bus for this route with tickets for a bus from Pisa to Madrid costing on average $53 (€42).
A flight is $303 (€242) less than a train for this route with tickets for a train from Pisa to Madrid costing on average $344 (€274).
Other travel options to Madrid take longer:
Bus takes on average 27h 15m.
Train takes on average 28h 36m.
- Around 6 flights per day.
- Around 5 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Pisa and Madrid as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Madrid Barajas Airport.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Madrid, Estación Sur de Autobuses.
- Travel with FlixBus, Lirosi Linee to go to Madrid by bus.
- Travel with Regionale to go to Madrid by train.
- Travel with KM Malta Airlines, Ryanair, KLM, Lufthansa, Vueling Airlines to go to Madrid by flight.
- 1 direct flights per day with KM Malta Airlines.
Travelling from Pisa to Madrid: related information
Here are some other resources that might have the information you need


