Travel Information
Compare train, bus, and flight for Pisa to Madrid
Omio recommends booking the flight as it is the most popular option from Pisa to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from $69. For those with little time consider booking a flight which can get you there in 3h 38m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.0kg. The ticket price range depends on the travel mode: a bus costs an average of $69, and a train costs an average of $262.
Distance: 757 miles (1219 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$240 Average price | $145 Average price Cheapest | $262 Average price |
6h 38m Average total duration Fastest 3h 38m Onboard + 3h 0m Additional time* | 23h 19m Average total duration 22h 49m Onboard + 30m Additional time* | 45h 53m Average total duration 45h 23m Onboard + 30m Additional time* |
3.7 - 7.3kg CO2 emissions | 1.2 - 3.0kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Madrid:
A bus is $95 (€77) less than a flight for this route with tickets for a flight from Pisa to Madrid costing on average $240 (€194).
A bus is $117 (€94) less than a train for this route with tickets for a train from Pisa to Madrid costing on average $262 (€211).
Other travel options to Madrid take longer:
Bus takes on average 22h 49m.
Train takes on average 45h 23m.
Travel optionsfrom Pisa to Madrid
How to get from Pisa to Madrid by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Madrid is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus11:30 PM40h05Pisa, Aeroporto Parcheggio Aurelia3:35 PMMadrid, Estación Sur de Autobuses$1211One-way2 transfers
Cheapest
FlixBus · FlixBus · FlixBus11:30 PM40h05Pisa, Aeroporto Parcheggio Aurelia3:35 PMMadrid, Estación Sur de Autobuses$1211One-way2 transfers
Fastest
LH1114+
LH740110:35 AM5h25Pisa International Airport4:00 PMMadrid Barajas Airport$4051One-way1 transfer
Other options
FlixBus · FlixBus · FlixBus11:30 PM39h25Pisa, Aeroporto Parcheggio Aurelia2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$1311One-way2 transfers
FlixBus · FlixBus5:45 AM28h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:30 AMMadrid, Estación Sur de Autobuses$1421One-way1 transfer
FlixBus · FlixBus · FlixBus5:45 AM33h10Pisa, Via delle Fiamme Gialle (Park Pietrasantina)2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$1791One-way2 transfers
Regionale Veloce 4125 · Regionale 20443+
W460135:37 AM14h13Pisa Centrale7:50 PMMadrid Barajas Airport$2301One-way2 transfers
InterCityNotte 799+
Regionale 20401+
W460132:56 AM16h54Pisa Centrale7:50 PMMadrid Barajas Airport$2431One-way2 transfers
Intercity 501+
Regionale 20449+
W460136:47 AM13h03Pisa Centrale7:50 PMMadrid Barajas Airport$2461One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Pisa to Madrid
Travel to Madrid easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Madrid.

This is compared to other travel options from Pisa to Madrid:
A bus is $95 (€77) less than a flight for this route with tickets for a flight from Pisa to Madrid costing on average $240 (€194).
A bus is $117 (€94) less than a train for this route with tickets for a train from Pisa to Madrid costing on average $262 (€211).
Other travel options to Madrid take longer:
Bus takes on average 22h 49m.
Train takes on average 45h 23m.
- Around 6 flights per day.
- Around 5 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Pisa and Madrid as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Madrid Barajas Airport.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Madrid, Estación Sur de Autobuses.
- Travel with FlixBus to go to Madrid by bus.
- Travel with Intercity to go to Madrid by train.
- Travel with Malta Air, Ryanair, KLM, Lufthansa, Vueling to go to Madrid by flight.
- 1 direct flights per day with Malta Air, Ryanair.
Travelling from Pisa to Madrid: related information
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