Travel Information
Compare train, bus, and flight for Lyon to Pisa
Omio recommends booking the bus as it is the most popular option from Lyon to Pisa among Omio's users. If you are prioritising price take the bus with prices starting from $53. For those with little time consider booking a train which can get you there in 9h 43m. The ticket price range depends on the travel mode: a bus costs an average of $53, and a train costs an average of $88.
Distance: 306 miles (493 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$94 Average price Cheapest | $135 Average price |
10h 32m Average total duration 10h 2m Onboard + 30m Additional time* | 10h 13m Average total duration Fastest 9h 43m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Travel optionsfrom Lyon to Pisa
How to get from Lyon to Pisa by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Pisa is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus9:35 AM12h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:55 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$1211One-way1 transfer
Cheapest
FlixBus · FlixBus11:00 PM14h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:20 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$1181One-way1 transfer
Fastest
U24421+
Regionale 20749+
InterCityNotte 796+
Regionale 25948:20 PM9h25Lyon Saint Exupery Airport5:45 AMPisa Centrale$2191One-way3 transfers
Other options
FlixBus · FlixBus10:50 AM13h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:20 AMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$1291One-way1 transfer
FlixBus · FlixBus6:15 AM15h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:35 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$1401One-way1 transfer
FlixBus · FlixBus12:05 AM13h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:20 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$1681One-way1 transfer
U24421+
Regionale 20749+
InterCityNotte 7968:20 PM9h29Lyon Saint Exupery Airport5:49 AMPisa Centrale$2171One-way2 transfers
U24415+
Regionale 20663 · Regionale Veloce 41347:10 AM11h05Lyon Saint Exupery Airport6:15 PMPisa Centrale$2581One-way2 transfers
U24415+
Regionale 20681 · Regionale Veloce 41367:10 AM13h25Lyon Saint Exupery Airport8:35 PMPisa Centrale$2581One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Lyon to Pisa
Travel to Pisa easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Pisa.

This is compared to other travel options from Lyon to Pisa:
A bus is $35 (€28) less than a train for this route with tickets for a train from Lyon to Pisa costing on average $88 (€70).
A bus is $165 (€131) less than a flight for this route with tickets for a flight from Lyon to Pisa costing on average $218 (€174).
Other travel options to Pisa take longer:
Bus takes on average 12h 20m.
Flight takes on average 5h 20m.
- Around 5 buses per day.
- Around 4 flights per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Pisa as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Pisa International Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Pisa Centrale.
- Buses mostly depart from Lyon, Perrache Bus Station and arrive in Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
- Travel with FlixBus, BlaBlaCar, BlaBlaCar Bus to go to Pisa by bus.
- Travel with Trenitalia, Regionale, SNCF to go to Pisa by train.
- 0 direct buses per day with BlaBlaCar.
Travelling from Lyon to Pisa: related information
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