Travel Information
Compare train, bus, and flight for Lyon to Pisa
Omio recommends booking the bus as it is the most popular option from Lyon to Pisa among Omio's users. If you are prioritising price take the bus with prices starting from $58. For those with little time consider booking a train which can get you there in 9h 10m. The ticket price range depends on the travel mode: a bus costs an average of $58, and a train costs an average of $148.
Distance: 306 miles (493 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$98 Average price Cheapest | $179 Average price | $285 Average price (fuel + tolls) |
10h 28m Average total duration 9h 58m Onboard + 30m Additional time* | 9h 40m Average total duration Fastest 9h 10m Onboard + 30m Additional time* | 7h 14m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon to Pisa:
A bus is $81 (€67) less than a train for this route with tickets for a train from Lyon to Pisa costing on average $179 (€147).
A bus is $631 (€518) less than a flight for this route with tickets for a flight from Lyon to Pisa costing on average $729 (€598).
Other travel options to Pisa take longer:
Bus takes on average 9h 58m.
Flight takes on average 14h 55m.
Travel optionsfrom Lyon to Pisa
How to get from Lyon to Pisa by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Pisa is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus10:50 AM13h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:20 AMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$961One-way1 transfer
Cheapest
FlixBus · FlixBus10:50 AM13h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:20 AMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$961One-way1 transfer
Fastest
FRECCIAROSSA 1000 9281+
8143+
Regionale Veloce 40459:28 AM8h23Lyon Part Dieu5:51 PMPisa Centrale$2931One-way2 transfers
Other options
FRECCIAROSSA 1000 9281+
9955+
Regionale 183199:28 AM11h36Lyon Part Dieu9:04 PMPisa Centrale$2711One-way2 transfers
FRECCIAROSSA 1000 9281+
9955+
Regionale 183239:28 AM12h00Lyon Part Dieu9:28 PMPisa Centrale$2711One-way2 transfers
FlixBus · FlixBus9:35 AM12h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:55 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$1081One-way1 transfer
FlixBus · FlixBus11:00 PM14h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:20 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$1081One-way1 transfer
FlixBus · FlixBus6:15 AM15h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:35 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$1411One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Lyon to Pisa
Travel to Pisa easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Pisa.

This is compared to other travel options from Lyon to Pisa:
A bus is $81 (€67) less than a train for this route with tickets for a train from Lyon to Pisa costing on average $179 (€147).
A bus is $631 (€518) less than a flight for this route with tickets for a flight from Lyon to Pisa costing on average $729 (€598).
Other travel options to Pisa take longer:
Bus takes on average 9h 58m.
Flight takes on average 14h 55m.
- Around 5 buses per day.
- Around 4 flights per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Pisa as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Pisa International Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Pisa Centrale.
- Buses mostly depart from Lyon, Perrache Bus Station and arrive in Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
- Travel with Trenitalia, Regionale to go to Pisa by train.
- Travel with FlixBus, BlaBlaCar, BlaBlaCar Bus to go to Pisa by bus.
- 0 direct buses per day with BlaBlaCar.
Travelling from Lyon to Pisa: related information
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