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4.6
Travel Information
Compare bus, train, and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $77 For those with little time, consider booking a flight, which has an average total journey time of 5h 11m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a bus costs an average of $77, while a flight costs an average of $382.
Distance: 445 miles (717 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$382 Average price | $181 Average price | $77 Average price Cheapest | $181 Average price (fuel + tolls) |
5h 11m Average total duration Fastest 3h 11m Onboard + 2h 0m Additional time* | 11h 23m Average total duration 10h 53m Onboard + 30m Additional time* | 15h 44m Average total duration 15h 14m Onboard + 30m Additional time* | 8h 49m Average total duration (door-to-door) |
2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | 0.7 - 1.8kg CO2 emissions | - CO2 emissions |
 Most popular airline |  Most popular train company |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Brussels:
A bus is $105 (€88) less than a train for this route with tickets for a train from Prague to Brussels costing on average $181 (€152).
A bus is $306 (€257) less than a flight for this route with tickets for a flight from Prague to Brussels costing on average $382 (€321).
Other travel options to Brussels take longer:
Train takes on average 11h 23m.
Bus takes on average 15h 44m.
You'll arrive about 5h 38m sooner (3h 11m by flight vs 8h 49m by car). Tickets start at around $382 (€321) compared to roughly $181 (€151) in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Prague to Brussels
How to get from Prague to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Prague to Brussels is by taking a bus because it’s the best combination of price and speed.
(Prague -> London)6:00 PM12h00Praha, ÚAN Florenc6:00 AMBrussels, Brussels South (Gare du Midi)$601One-way0 transfers
Cheapest
- (Prague -> London)6:00 PM12h00Praha, ÚAN Florenc6:00 AMBrussels, Brussels South (Gare du Midi)$601One-way0 transfers
Fastest
FR 692:05 PM1h30Prague Vaclav Havel Airport3:35 PMBrussels South Charleroi Airport$951One-way0 transfers
Other options
- rj 512 · Sp 5286 · ICE 26 · ICE 1010:35 AM11h00Prague hlavní nádraží9:35 PMBrussels-Midi$1021One-way3 transfers
- IC 564 · Sp 5284 · ICE 28 · ICE 128:35 AM11h00Prague hlavní nádraží7:35 PMBrussels-Midi$1021One-way3 transfers
- rj 382 · ICE 1556 · ICE 31810:31 AM13h04Prague hlavní nádraží11:35 PMBrussels-Midi$1131One-way2 transfers
- FlixBus11:05 PM14h50Praha, ÚAN Florenc1:55 PMBrussels, Brussels South (Gare du Midi)$761One-way0 transfers
- FlixBus4:15 PM15h05Praha, ÚAN Florenc7:20 AMBrussels, Brussels South (Gare du Midi)$761One-way0 transfers
- FlixBus · FlixBus2:30 PM16h50Praha, Černý Most7:20 AMBrussels, Brussels South (Gare du Midi)$811One-way1 transfer
- FR 21229:50 AM1h30Prague Vaclav Havel Airport11:20 AMBrussels South Charleroi Airport$1281One-way0 transfers
SN28126:45 PM1h30Prague Vaclav Havel Airport8:15 PMBrussels Airport$2681One-way0 transfers
KL1350 · KL17036:00 AM3h40Prague Vaclav Havel Airport9:40 AMBrussels Airport$3111One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Prague to Brussels
The Best Way According to our Users
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FAQs: Travel from Prague to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Brussels.
This is compared to other travel options from Prague to Brussels:
A bus is $105 (€88) less than a train for this route with tickets for a train from Prague to Brussels costing on average $181 (€152).
A bus is $306 (€257) less than a flight for this route with tickets for a flight from Prague to Brussels costing on average $382 (€321).
Other travel options to Brussels take longer:
Train takes on average 11h 23m.
Bus takes on average 15h 44m.
- Around 46 flights per day.
- Around 12 buses per day.
- Around 8 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Brussels as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Brussels Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Brussels-Midi.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with České dráhy, Deutsche Bahn, Alibus to go to Brussels by train.
- Travel with Ryanair, Buzz, Brussels Airlines, Smartwings, KLM, Lot Polish Airlines, KLM Cityhopper, Sas Airways, Helvetic Airways, Lufthansa, Air Baltic, Swiss, Qatar Airways, tarom, Norwegian Air Shuttle, Croatia Airlines, Egypt Air, British Airways, Edelweiss Air, CitizenPlane, Air Dolomiti, Austrian Airlines, Turkish Airlines, TAP Portugal to go to Brussels by flight.
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- 0 direct trains per day with Alibus.
- 4 direct flights per day with Ryanair, Buzz, Brussels Airlines, Smartwings, CitizenPlane.
- 2 direct buses per day with FlixBus.
Travelling from Prague to Brussels: related information
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