How to travel from Prague to Brussels

There are 3 options to travel between Prague and Brussels including taking a bus, train, and flight.

The cheapest way to travel from Prague to Brussels is a bus with an average price of $85 (€68).

This is compared to other travel options from Prague to Brussels:

A bus is $21 (€17) less than a train for this route with tickets for a train from Prague to Brussels costing on average $106 (€86).

A bus is $69 (€56) less than a flight for this route with tickets for a flight from Prague to Brussels costing on average $154 (€124).

The fastest way to travel from Prague to Brussels is by flight with an average journey time of 5h 17m.

Other travel options to Brussels take longer:

Train takes on average 12h 15m.

Bus takes on average 15h 26m.

The distance from Prague to Brussels is approximately 445 miles (717 km).

The average frequency per day from Prague to Brussels is:

• Around 41 flights per day.
• Around 14 buses per day.
• Around 8 trains per day.

However, we recommend checking specific travel dates for your route between Prague and Brussels as scheduled services by bus, train, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Prague to Brussels:

• Flights mostly depart from Prague Vaclav Havel Airport and arrive in Brussels Airport.
• Trains mostly depart from Prague hlavní nádraží and arrive in Brussels-Midi.
• Buses mostly depart from Praha, ÚAN Florenc and arrive in Brussels, Brussels South (Gare du Midi).

If finding a good deal is your main consideration for your trip from Prague to Brussels, then we'll help you find the best value travel companies for you:

• Travel with České dráhy, Deutsche Bahn, Alibus, ÖBB | Euro City (EC), České dráhy (ČD), ÖBB | Railjet to go to Brussels by train.
• Travel with Ryanair, Buzz, Brussels Airlines, Smartwings, KLM, Lot Polish Airlines, KLM Cityhopper, Sas Airways, Lufthansa, Helvetic Airways, Swiss, Air Baltic, Lufthansa Cityline to go to Brussels by flight.
• Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.

Yes, there are direct services available from Prague to Brussels with the following travel companies:

• 0 direct trains per day with Alibus.
• 4 direct flights per day with Buzz, Brussels Airlines, Smartwings.
• 2 direct buses per day with FlixBus.

Omio customers who travel from Prague to Brussels often also extend their vacation to go to Paris, Amsterdam, Bruges, London, Luxembourg. Omio can help you plan your trip by finding the best connections between Brussels and these popular destinations at a great price.

Most travelers need at least three days in Brussels to see the main sights at a comfortable pace. If you want day trips or a slower itinerary, consider adding extra time.

In Brussels, explore the vibrant Marolles district with its antique shops and street art, and enjoy a stroll through Parc du Cinquantenaire with its impressive arches and museums. Sample Belgian chocolates at the city's renowned chocolatiers, and experience the lively Saint-Géry district's trendy bars and cafes. Attend a performance at the historic La Monnaie opera house. Don't miss top sights like the opulent Grand Place, Atomium for panoramic views, the iconic Manneken Pis statue, the Royal Palace of Brussels, and the Magritte Museum.

For a fulfilling experience in Brussels, plan on spending 2 to 3 days to explore key attractions such as the Grand Place, Atomium, and various museums, as well as to enjoy the local cuisine and vibrant neighborhoods.