How to travel from Prague to Brussels

Fri, Dec 05
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Travel by train, bus, flight with
FlixBus
Ryanair
Deutsche Bahn
Brussels Airlines
European Sleeper
1,000+ more
FlixBus
Ryanair
Deutsche Bahn
Brussels Airlines
European Sleeper
1,000+ more
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Travel Information between Prague and Brussels

Distance445 miles (717 km)
Available travel modesTrain, bus or flight
Ticket price range$44 - $65
Cheapest modeBus • $44 (€40) • 12 h
Fastest modeFlight • $45 (€41) • 1 h 30 min
Popular travel companiesFlixBus, Ryanair or Deutsche Bahn

Travel 445 miles (717 km) by train, bus or flight from Prague to Brussels. The most popular travel companies which serve this route are FlixBus, Ryanair or Deutsche Bahn among others. Travelers can even take a direct bus, flight or train from Prague to Brussels.

Travel options
from Prague to Brussels

How to get from Prague to Brussels by train, bus or flight.

Our recommendation

flight

The best way to travel from Prague to Brussels is by taking a flight because it’s the best combination of price and speed.

SmartwingsQS1002
05:15PM1h30
Prague Vaclav Havel Airport
06:45PMBrussels Airport
$1031One-way
0 transfers

Cheapest

Regiojet(Prague -> London)
06:00PM12h00
Praha, ÚAN Florenc
06:00AMBrussels, Brussels South (Gare du Midi)
$801One-way
0 transfers

Fastest

SmartwingsQS1002
05:15PM1h30
Prague Vaclav Havel Airport
06:45PMBrussels Airport
$1031One-way
0 transfers

Other options

Deutsche BahnEC 458 · Bus 10458 · IC 2508 · ICE 699
06:28PM15h07
Prague hlavní nádraží
09:35AMBrussels-Midi
$1761One-way
4 transfers
Deutsche BahnEX 358 · RE 3568 · ICE 624 · ICE 814
09:35AM12h00
Prague hlavní nádraží
09:35PMBrussels-Midi
$2891One-way
4 transfers
Deutsche BahnEX 352 · ICE 20 · ICE 18
03:35PM18h00
Prague hlavní nádraží
09:35AMBrussels-Midi
$2891One-way
2 transfers
FlixBusFlixBus
04:15PM15h05
Praha, ÚAN Florenc
07:20AMBrussels, Brussels South (Gare du Midi)
$1011One-way
0 transfers
FlixBusFlixBus · FlixBus
04:15PM17h45
Praha, ÚAN Florenc
10:00AMBrussels, Gare Du Midi
$1041One-way
1 transfer
FlixBusFlixBus · FlixBus
06:00PM18h25
Praha, ÚAN Florenc
12:25PMBrussels, Avenue des Magnolias (King Baudouin)
$1071One-way
1 transfer
SmartwingsQS1000
06:40AM1h30
Prague Vaclav Havel Airport
08:10AMBrussels Airport
$1031One-way
0 transfers
BuzzFR 69
06:25PM1h30
Prague Vaclav Havel Airport
07:55PMBrussels South Charleroi Airport
$1311One-way
0 transfers
easyJetU27928+Eurostar9388
09:20AM11h46
Prague Vaclav Havel Airport
09:06PMBrussels-Midi
$3041One-way
1 transfer

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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How to get from Prague to Brussels

The Best Way According to our Users

When it comes to choosing a method of transportation from Prague to Brussels, 70,86% of our customers do not hesitate to choose the flight as their preferred way to travel. Nowadays, passengers who want to fly around Europe have more options than ever before. With dozens of budget airlines covering several routes which connect to virtually all European countries, taking a flight to reach your desired destination is easy and inexpensive. The low fares and the short flight time are, among others, some of the reasons why our users choose the airplane as the best way to get from Prague to Brussels, even if they have to face baggage limitations and long lines at check-in and security control. You can book your flights with Omio to make sure you are always taking the fastest route or getting the best deal. You can also add extra luggage and book securely with several methods of payment such as Apple Pay, PayPal and more.

Search on Omio to find cheap tickets from Prague to Brussels. It’s easy to find the most attractive prices and choose your preferred route for your journey. Book on web or app, and travel with your mobile ticket —without the stress of printing your ticket.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Travel from Prague to Brussels

Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Brussels.

FAQs

You can get between Prague and Brussels 3 different ways: train, bus or flight.

The cheapest way to travel from Prague to Brussels is a bus with an average price of $44 (€40).

This is compared to other travel options from Prague to Brussels:

Taking a bus costs $1 (€1) less than taking a flight, which costs on average $45 (€41) for the same trip.

A bus is $21 (€19) less than a train for this trip with tickets for a train from Prague to Brussels costing on average $65 (€59).

The quickest way to travel from Prague to Brussels is by flight, which takes on average 1 h 30 min   compared to other travel options that take longer:

Bus takes 12 h on average.

Train takes 11 h on average.

The distance is approximately 445 miles (717 km) from Prague to Brussels.

The average frequency per day from Prague to Brussels is:

  • Around 37 buses per day.
  • Around 33 flights per day.
  • 5 trains a day.

However, we recommend checking specific travel dates for your trip between Prague and Brussels as scheduled services by train, bus or flight can vary by season or day of the week.

These are the most popular departure and arrival points when traveling from Prague to Brussels:

  • Most travelers take a bus from Prague, Central Train Station to Brussels, Brussels South (Gare du Midi).
  • Most travelers who buy a plane ticket from Prague to Brussels depart from Prague Vaclav Havel Airport to Brussels Airport.

Omio works with many trusted partners that can help you travel the best way from Prague to Brussels:

  • You can travel to Brussels from Prague by bus with FlixBus or BlaBlaCar Bus. You can find cheap tickets on Omio for $45 (€41) with FlixBus from Prague to Brussels.
  • You can travel to Brussels from Prague by flight with Ryanair, Brussels Airlines, KLM, KLM Cityhopper, LOT Polish Airlines, CityJet, SAS, LAER, SWISS, Lufthansa Cityline (2) or Air Dolomiti. You can find cheap tickets on Omio for $45 (€41) with Ryanair from Prague to Brussels.
  • You can go to Brussels from Prague by train with Deutsche Bahn or European Sleeper. You'll see cheap train tickets for $65 (€59) with European Sleeper from Prague to Brussels on Omio.

Yes, there are direct routes from Prague to Brussels with the following travel companies:

  • You can find 4 direct buses per day to take to Brussels with FlixBus.
  • You'll find 2 direct flights a day to Brussels with Brussels Airlines.
  • You can find 1 direct train per day to take to Brussels with European Sleeper.

Direct services to Brussels tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your journey.

Looking to extend your trip from Prague to Brussels? Many Omio customers who go from Prague to Brussels usually extend their vacation to explore other popular destinations like Paris, Amsterdam, Bruges, London or Berlin. If you're looking to explore Paris, Amsterdam, Bruges, London or Berlin from Brussels, let Omio find you the best connections available at an affordable price.
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