Travel Information
Compare train, bus, and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $49. For those with little time consider booking a flight which can get you there in 3h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $49, and a flight costs an average of $27.
Distance: 445 miles (717 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$157 Average price | $125 Average price | $85 Average price Cheapest | $185 Average price (fuel + tolls) |
6h 21m Average total duration Fastest 3h 21m Onboard + 3h 0m Additional time* | 12h 20m Average total duration 11h 50m Onboard + 30m Additional time* | 15h 24m Average total duration 14h 54m Onboard + 30m Additional time* | 8h 49m Average total duration (door-to-door) |
2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | 0.7 - 1.8kg CO2 emissions | - CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Brussels:
A bus is $40 (€32) less than a train for this route with tickets for a train from Prague to Brussels costing on average $125 (€101).
A bus is $72 (€58) less than a flight for this route with tickets for a flight from Prague to Brussels costing on average $157 (€127).
Other travel options to Brussels take longer:
Train takes on average 11h 50m.
Bus takes on average 14h 54m.
Travel optionsfrom Prague to Brussels
How to get from Prague to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Prague to Brussels is by taking a bus because it’s the best combination of price and speed.
3:15 PM15h05Prague6:20 AMBrussels$761One-way0 transfers
Cheapest
3:15 PM15h05Prague6:20 AMBrussels$761One-way0 transfers
Fastest
10:05 PM14h50Prague12:55 PMBrussels$861One-way0 transfers
Other options
1:30 PM16h50Prague6:20 AMBrussels$851One-way0 transfers
2:15 PM15h05Prague5:20 AMBrussels$881One-way0 transfers
9:05 PM14h50Prague11:55 AMBrussels$961One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Prague to Brussels
The Best Way According to our Users
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FAQs: Travel from Prague to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Brussels.

This is compared to other travel options from Prague to Brussels:
A bus is $40 (€32) less than a train for this route with tickets for a train from Prague to Brussels costing on average $125 (€101).
A bus is $72 (€58) less than a flight for this route with tickets for a flight from Prague to Brussels costing on average $157 (€127).
Other travel options to Brussels take longer:
Train takes on average 11h 50m.
Bus takes on average 14h 54m.
- Around 39 flights per day.
- Around 15 buses per day.
- Around 7 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Brussels Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Brussels-Midi.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- Travel with Deutsche Bahn, České dráhy, Alibus, ÖBB | Euro City (EC), České dráhy (ČD), ÖBB | Railjet to go to Brussels by train.
- Travel with Ryanair, Brussels Airlines, Buzz, Smartwings, KLM, Lot Polish Airlines, KLM Cityhopper, Cityjet, Lufthansa, Sas Airways, Helvetic Airways, Swiss, Air Baltic, Lufthansa Cityline, TAP Portugal to go to Brussels by flight.
- 2 direct buses per day with FlixBus.
- 0 direct trains per day with Alibus.
- 4 direct flights per day with Ryanair, Brussels Airlines, Buzz, Smartwings.
Travelling from Prague to Brussels: related information
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