4.9
4.6
Travel Information
Compare bus, train, and flight for Madrid to Brussels
Omio recommends booking the flight as it is the most popular option from Madrid to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $109 For those with little time, consider booking a flight, which has an average total journey time of 6h 39m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 1.3 - 3.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $109, while a flight costs an average of $495.
Distance: 817 miles (1316 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
$495 Average price | $109 Average price Cheapest | $307 Average price (fuel + tolls) |
6h 39m Average total duration Fastest 4h 39m Onboard + 2h 0m Additional time* | 21h 38m Average total duration 21h 8m Onboard + 30m Additional time* | 16h 17m Average total duration (door-to-door) |
3.9 - 7.9kg CO2 emissions | 1.3 - 3.3kg CO2 emissions Lowest | - CO2 emissions |
 Most popular airline |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Madrid to Brussels
Compare the available ways to get from Madrid to Brussels, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Madrid to Brussels:
A bus is $387 less than a flight for this route with tickets for a flight from Madrid to Brussels costing on average $495.
Other travel options to Brussels take longer:
Bus takes on average 21h 38m.
You'll arrive about 11h 38m sooner (4h 39m by flight vs 16h 17m by car). Tickets start at around $495 compared to roughly $307 in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Madrid to Brussels
How to get from Madrid to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Madrid to Brussels is by taking a bus because it’s the best combination of price and speed.
3162 · 503216:35 PM 20h40 Madrid, Estación Sur de Autobuses 3:15 PM Brussels, Brussels South (Gare du Midi) $151 1 One-way 1 transfer
Cheapest
- 3162 · 50321
6:35 PM 20h40 Madrid, Estación Sur de Autobuses 3:15 PM Brussels, Brussels South (Gare du Midi) $151 1 One-way 1 transfer
Fastest
SN37326:25 AM 2h25 Madrid Barajas Airport 8:50 AM Brussels Airport $441 1 One-way 0 transfers
Other options
- 3160 · 50100
10:30 PM 22h20 Madrid, Estación Sur de Autobuses 8:50 PM Brussels, Brussels South (Gare du Midi) $177 1 One-way 1 transfer - 4004 · 1657
3:30 PM 20h30 Madrid, Estación Sur de Autobuses 12:00 PM Brussels, Brussels South (Gare du Midi) $203 1 One-way 1 transfer - FlixBus · FlixBus
10:55 PM 24h35 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) 11:30 PM Brussels, Brussels South (Gare du Midi) $239 1 One-way 1 transfer
KL1508 · KL17018:30 PM 11h05 Madrid Barajas Airport 7:35 AM Brussels Airport $291 1 One-way 1 transfer
AZ59+SN31765:55 AM 6h20 Madrid Barajas Airport 12:15 PM Brussels Airport $295 1 One-way 1 transfer- AZ59+AZ7640
5:55 AM 6h20 Madrid Barajas Airport 12:15 PM Brussels Airport $349 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
How to get from Madrid to Brussels
The Best Way According to our Users
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FAQs: Travel from Madrid to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Madrid to Brussels.
This is compared to other travel options from Madrid to Brussels:
A bus is $387 less than a flight for this route with tickets for a flight from Madrid to Brussels costing on average $495.
Other travel options to Brussels take longer:
Bus takes on average 21h 38m.
- Around 45 flights per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Madrid and Brussels as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Madrid Barajas Airport and arrive in Brussels Airport.
- Buses mostly depart from Madrid, Estación Sur de Autobuses and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with TAP Portugal, Iberia, KLM, ITA, Lufthansa, Qatar Airways, Air Europa, Brussels Airlines, Turkish Airlines, Royal Air Maroc, Ryanair, British Airways, Lot Polish Airlines, Lufthansa City Airlines, BA Cityflyer, CitizenPlane, Vueling, Air Baltic, Helvetic Airways, Swiss, KLM Cityhopper, Norwegian Air Shuttle, Lufthansa Cityline, Egypt Air, Air Serbia to go to Brussels by flight.
- Travel with FlixBus, BlaBlaCar Bus, Infobus, Internorte, Alsa to go to Brussels by bus.
- 10 direct flights per day with Iberia, Air Europa, Brussels Airlines, Ryanair, CitizenPlane, Air Baltic.
Travelling from Madrid to Brussels: related information
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