Travel Information
Compare bus and flight for Florence to Brussels
Omio recommends booking the flight as it is the most popular option from Florence to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €108 For those with little time, consider booking a flight, which has an average total journey time of 5h 4m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.9 - 2.4kg. Average ticket prices depend on the travel mode: a bus costs an average of €108, while a flight costs an average of €302.
Distance: 585 miles (943 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
€302 Average price | €108 Average price Cheapest |
5h 4m Average total duration Fastest 3h 4m Onboard + 2h 0m Additional time* | 22h 9m Average total duration 21h 39m Onboard + 30m Additional time* |
2.8 - 5.7kg CO2 emissions | 0.9 - 2.4kg CO2 emissions Lowest |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Florence to Brussels:
A bus is €193 less than a flight for this route with tickets for a flight from Florence to Brussels costing on average €302.
Other travel options to Brussels take longer:
Bus takes on average 22h 9m.
Travel optionsfrom Florence to Brussels
How to get from Florence to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Florence to Brussels is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus5:05 AM27h10Firenze, Piazzale Montelungo8:15 AMBrussels, Brussels South (Gare du Midi)€741One-way2 transfers
Cheapest
FlixBus · FlixBus · FlixBus5:05 AM27h10Firenze, Piazzale Montelungo8:15 AMBrussels, Brussels South (Gare du Midi)€741One-way2 transfers
Fastest
FR 37469:15 AM1h45Pisa International Airport11:00 AMBrussels South Charleroi Airport€781One-way0 transfers
Other options
FlixBus · FlixBus · FlixBus12:00 PM24h20Scandicci, Villa Costanza (Florence)12:20 PMBrussels, Brussels South (Gare du Midi)€771One-way2 transfers
FlixBus · FlixBus · FlixBus11:15 AM25h30Florence, Guidoni Tram T212:45 PMBrussels, Brussels South (Gare du Midi)€791One-way2 transfers
FlixBus · FlixBus12:30 PM24h15Scandicci, Villa Costanza (Florence)12:45 PMBrussels, Brussels South (Gare du Midi)€801One-way1 transfer
FR 37478:50 PM1h45Pisa International Airport10:35 PMBrussels South Charleroi Airport€781One-way0 transfers
VY681412:45 PM1h55Florence Peretola Airport2:40 PMBrussels Airport€911One-way0 transfers
VY6028 · VY898010:05 PM11h40Florence Peretola Airport9:45 AMBrussels Airport€1361One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Florence to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Florence to Brussels.

This is compared to other travel options from Florence to Brussels:
A bus is €193 less than a flight for this route with tickets for a flight from Florence to Brussels costing on average €302.
Other travel options to Brussels take longer:
Bus takes on average 22h 9m.
- Around 40 flights per day.
- Around 13 buses per day.
However, we recommend checking specific travel dates for your route between Florence and Brussels as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Florence Peretola Airport and arrive in Brussels Airport.
- Buses mostly depart from Scandicci, Villa Costanza (Florence) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Lufthansa Cityline, KLM Cityhopper, Swiss, BA Cityflyer, Brussels Airlines, KLM, Air Dolomiti, Austrian Airlines, Lufthansa, Vueling, Air Baltic, Helvetic Airways, Malta Air, ITA, British Airways, Ryanair, Edelweiss Air to go to Brussels by flight.
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- 4 direct flights per day with Brussels Airlines, Malta Air, Ryanair.
Travelling from Florence to Brussels: related information
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