Travel Information
Compare bus and flight for Florence to Brussels
Omio recommends booking the flight as it is the most popular option from Florence to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $126 For those with little time, consider booking a flight, which has an average total journey time of 5h 2m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.9 - 2.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $126, while a flight costs an average of $355.
Distance: 585 miles (943 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
$355 Average price | $126 Average price Cheapest |
5h 2m Average total duration Fastest 3h 2m Onboard + 2h 0m Additional time* | 22h 10m Average total duration 21h 40m Onboard + 30m Additional time* |
2.8 - 5.7kg CO2 emissions | 0.9 - 2.4kg CO2 emissions Lowest |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Florence to Brussels
Compare the available ways to get from Florence to Brussels, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Florence to Brussels:
A bus is $230 (€194) less than a flight for this route with tickets for a flight from Florence to Brussels costing on average $355 (€299).
Other travel options to Brussels take longer:
Bus takes on average 22h 10m.
Travel optionsfrom Florence to Brussels
How to get from Florence to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Florence to Brussels is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus2:15 AM 24h50 Firenze, Piazzale Montelungo 3:05 AM Brussels, Brussels South (Gare du Midi) $173 1 One-way 2 transfers
Cheapest
FlixBus · FlixBus · FlixBus2:15 AM 24h50 Firenze, Piazzale Montelungo 3:05 AM Brussels, Brussels South (Gare du Midi) $173 1 One-way 2 transfers
Fastest
FR 39387:10 AM 1h45 Bologna Airport 8:55 AM Brussels South Charleroi Airport $190 1 One-way 0 transfers
Other options
FlixBus · FlixBus · FlixBus2:40 AM 24h25 Scandicci, Villa Costanza (Florence) 3:05 AM Brussels, Brussels South (Gare du Midi) $174 1 One-way 2 transfers
FlixBus · FlixBus · FlixBus12:05 AM 25h05 Scandicci, Villa Costanza (Florence) 1:10 AM Brussels, Brussels South (Gare du Midi) $176 1 One-way 2 transfers
FlixBus · FlixBus · FlixBus11:40 PM 25h30 Firenze, Piazzale Montelungo 1:10 AM Brussels, Brussels South (Gare du Midi) $181 1 One-way 2 transfers
KL1656 · KL17015:05 PM 14h30 Florence Peretola Airport 7:35 AM Brussels Airport $270 1 One-way 1 transfer
KL1656 · KL17035:05 PM 17h05 Florence Peretola Airport 10:10 AM Brussels Airport $270 1 One-way 1 transfer
KL1656 · KL17075:05 PM 5h15 Florence Peretola Airport 10:20 PM Brussels Airport $474 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Florence to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Florence to Brussels.

This is compared to other travel options from Florence to Brussels:
A bus is $230 (€194) less than a flight for this route with tickets for a flight from Florence to Brussels costing on average $355 (€299).
Other travel options to Brussels take longer:
Bus takes on average 22h 10m.
- Around 38 flights per day.
- Around 13 buses per day.
However, we recommend checking specific travel dates for your route between Florence and Brussels as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Florence Peretola Airport and arrive in Brussels Airport.
- Buses mostly depart from Scandicci, Villa Costanza (Florence) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- Travel with ITA, Brussels Airlines, Vueling, Air Dolomiti, Malta Air, KLM, Helvetic Airways, KLM Cityhopper, British Airways, Ryanair, Swiss, Austrian Airlines, BA Cityflyer, Air Baltic, Edelweiss Air, CitizenPlane, Lufthansa, Lufthansa Cityline to go to Brussels by flight.
- 4 direct flights per day with Brussels Airlines, Malta Air, Ryanair, CitizenPlane.
Travelling from Florence to Brussels: related information
Here are some other resources that might have the information you need

