Travel Information
Compare bus and flight for Florence to Brussels
Omio recommends booking the flight as it is the most popular option from Florence to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from $23. For those with little time consider booking a flight which can get you there in 2h 22m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.4kg. The ticket price range depends on the travel mode: a flight costs an average of $23, and a bus costs an average of $69.
Distance: 585 miles (943 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
$88 Average price Cheapest | $107 Average price |
5h 22m Average total duration Fastest 2h 22m Onboard + 3h 0m Additional time* | 20h 41m Average total duration 20h 11m Onboard + 30m Additional time* |
2.8 - 5.7kg CO2 emissions | 0.9 - 2.4kg CO2 emissions Lowest |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Florence to Brussels:
A flight is $19 (€16) less than a bus for this route with tickets for a bus from Florence to Brussels costing on average $107 (€89).
Other travel options to Brussels take longer:
Bus takes on average 20h 11m.
Travel optionsfrom Florence to Brussels
How to get from Florence to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Florence to Brussels is by taking a flight because it’s the best combination of price and speed.
FR 39389:50 AM1h45Bologna Airport11:35 AMBrussels South Charleroi Airport$561One-way0 transfers
Cheapest
FR 39389:50 AM1h45Bologna Airport11:35 AMBrussels South Charleroi Airport$561One-way0 transfers
Fastest
FR 39389:50 AM1h45Bologna Airport11:35 AMBrussels South Charleroi Airport$561One-way0 transfers
Other options
94742 · 47392:15 PM18h25Scandicci, Villa Costanza (Florence)8:40 AMBrussels, Brussels South (Gare du Midi)$871One-way1 transfer
FlixBus · FlixBus · FlixBus4:15 AM27h05Firenze, Piazzale Montelungo7:20 AMBrussels, Brussels South (Gare du Midi)$1391One-way2 transfers
FlixBus · FlixBus · FlixBus4:45 PM23h00Scandicci, Villa Costanza (Florence)3:45 PMBrussels, Brussels South (Gare du Midi)$1421One-way2 transfers
FR 37461:10 PM1h45Pisa International Airport2:55 PMBrussels South Charleroi Airport$1051One-way0 transfers
FR 46836:35 PM1h45Bologna Airport8:20 PMBrussels South Charleroi Airport$1051One-way0 transfers
FR 37479:00 PM1h45Pisa International Airport10:45 PMBrussels South Charleroi Airport$1331One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Florence to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Florence to Brussels.

This is compared to other travel options from Florence to Brussels:
A flight is $19 (€16) less than a bus for this route with tickets for a bus from Florence to Brussels costing on average $107 (€89).
Other travel options to Brussels take longer:
Bus takes on average 20h 11m.
- Around 41 flights per day.
- Around 12 buses per day.
However, we recommend checking specific travel dates for your route between Florence and Brussels as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Florence Peretola Airport and arrive in Brussels Airport.
- Buses mostly depart from Scandicci, Villa Costanza (Florence) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Malta Air, Ryanair, Vueling, Brussels Airlines, ITA, KLM Cityhopper, Lufthansa, Helvetic Airways, Air Dolomiti to go to Brussels by flight.
- Travel with BlaBlaCar Bus, FlixBus to go to Brussels by bus.
- 3 direct flights per day with Malta Air, Ryanair, Brussels Airlines.
Travelling from Florence to Brussels: related information
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