Travel Information
Compare train, bus, and flight for Milan to Brussels
Omio recommends booking the flight as it is the most popular option from Milan to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $95 For those with little time, consider booking a flight, which has an average total journey time of 5h 21m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.7 - 1.7kg. Average ticket prices depend on the travel mode: a bus costs an average of $95, while a flight costs an average of $378.
Distance: 433 miles (698 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$378 Average price | $111 Average price | $95 Average price Cheapest | $265 Average price (fuel + tolls) |
5h 21m Average total duration Fastest 3h 21m Onboard + 2h 0m Additional time* | 9h 21m Average total duration 8h 51m Onboard + 30m Additional time* | 18h 3m Average total duration 17h 33m Onboard + 30m Additional time* | 10h 15m Average total duration (door-to-door) |
2.1 - 4.2kg CO2 emissions | - CO2 emissions | 0.7 - 1.7kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Brussels:
A bus is $16 (€13) less than a train for this route with tickets for a train from Milan to Brussels costing on average $111 (€92).
A bus is $282 (€234) less than a flight for this route with tickets for a flight from Milan to Brussels costing on average $378 (€313).
Other travel options to Brussels take longer:
Train takes on average 9h 21m.
Bus takes on average 18h 3m.
You'll arrive about 6h 54m sooner (3h 21m by flight vs 10h 15m by car). Tickets start at around $378 (€313) compared to roughly $265 (€220) in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Milan to Brussels
How to get from Milan to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Milan to Brussels is by taking a flight because it’s the best combination of price and speed.
FR 36599:55 AM1h35Milan Bergamo Orio al Serio Airport11:30 AMBrussels South Charleroi Airport$371One-way0 transfers
Cheapest
FR 36599:55 AM1h35Milan Bergamo Orio al Serio Airport11:30 AMBrussels South Charleroi Airport$371One-way0 transfers
Fastest
SN31506:50 PM1h30Milan Linate Airport8:20 PMBrussels Airport$1961One-way0 transfers
Other options
57202 · 143311:59 PM17h31Milano, Autostazione Lampugnano5:30 PMBrussels, Brussels South (Gare du Midi)$651One-way1 transfer
5710 · 16575:30 PM18h30Milano, Autostazione Lampugnano12:00 PMBrussels, Brussels South (Gare du Midi)$831One-way1 transfer
FlixBus · FlixBus7:15 PM17h30Milano, Autostazione Lampugnano12:45 PMBrussels, Brussels South (Gare du Midi)$1201One-way1 transfer
FR 45239:20 PM1h35Milan Bergamo Orio al Serio Airport10:55 PMBrussels South Charleroi Airport$601One-way0 transfers
FR 44755:15 PM1h35Milan Bergamo Orio al Serio Airport6:50 PMBrussels South Charleroi Airport$601One-way0 transfers
U254337:00 AM1h35Milan Linate Airport8:35 AMBrussels Airport$631One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Milan to Brussels
The Best Way According to our Users
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FAQs: Travel from Milan to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Brussels.

This is compared to other travel options from Milan to Brussels:
A bus is $16 (€13) less than a train for this route with tickets for a train from Milan to Brussels costing on average $111 (€92).
A bus is $282 (€234) less than a flight for this route with tickets for a flight from Milan to Brussels costing on average $378 (€313).
Other travel options to Brussels take longer:
Train takes on average 9h 21m.
Bus takes on average 18h 3m.
- Around 60 flights per day.
- Around 8 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Milan and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Milan Linate Airport and arrive in Brussels Airport.
- Trains mostly depart from Milan Centrale and arrive in Brussels-Midi.
- Buses mostly depart from Milano, Autostazione Lampugnano and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Lufthansa Cityline, KLM Cityhopper, KM Malta Airlines, BA Cityflyer, Brussels Airlines, Qatar Airways, Norwegian Air Shuttle, Gulf Air, Air Baltic, Helvetic Airways, Malta Air, British Airways, Ryanair, Edelweiss Air, Swiss, Transavia France, KLM, Air Dolomiti, Austrian Airlines, Lufthansa, Air Serbia, Vueling, AJet, Turkish Airlines, ITA, easyJet to go to Brussels by flight.
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- Travel with Trenitalia, Deutsche Bahn to go to Brussels by train.
- 14 direct flights per day with Brussels Airlines, Air Baltic, Malta Air, Ryanair, ITA, easyJet.
- 1 direct buses per day with BlaBlaCar Bus.
Travelling from Milan to Brussels: related information
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