- Must visit
Gutenberg Museum
One of the world’s most important museums of printing history, dedicated to Johannes Gutenberg and early bookmaking. A flagship Mainz attraction with historic presses and notable Bible displays.
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The cheapest and fastest trains from Lyon to Mainz
Showing times and prices for Jun 04
Cheapest price
$73
Average price
$136
Fastest journey
6 h 14 m
Average duration
6 h 28 m
Trains per day
2
Distance
536 km
Cheap tickets
The best way to find a cheap train ticket from Lyon to Mainz is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Mainz will cost around $136 if you buy it on the day, but the cheapest tickets can be found for only $73.
Fast trains
Of the 2 trains that leave Lyon for Mainz on Thu, Jun 04, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jun 04 the direct trains cover the 536 km distance in an average of 6 h 28 m but if you time it right, some trains will get you there in just 6 h 14 m .
On Thu, Jun 04 the slowest trains will take 6 h 42 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9:01 AM6h14Lyon3:15 PMMainz$731One-way0 transfers- 8:01 AM6h42Lyon2:43 PMMainz$1991One-way0 transfers
- 9:01 AM6h14Lyon3:15 PMMainz$731One-way0 transfers
- 8:01 AM6h42Lyon2:43 PMMainz$1991One-way0 transfers
Travel Information
Compare train, bus, and flight for Lyon to Mainz
Omio recommends booking the train as it is the most popular option from Lyon to Mainz among Omio's users. If you are prioritising price take the bus with prices starting from $42. For those with little time consider booking a flight which can get you there in 1h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $42, and a flight costs an average of $114.
Distance: 333 miles (536 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$136 Average price | $70 Average price Cheapest | $244 Average price | $183 Average price (fuel + tolls) |
6h 35m Average total duration 6h 5m Onboard + 30m Additional time* | 11h 27m Average total duration 10h 57m Onboard + 30m Additional time* | 4h 25m Average total duration Fastest 1h 25m Onboard + 3h 0m Additional time* | 6h 41m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.5 - 1.3kg CO2 emissions | 1.6 - 3.2kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Lyon to Mainz is a bus with an average price of $70 (€56).
This is compared to other travel options from Lyon to Mainz:
A bus is $66 (€54) less than a train for this route with tickets for a train from Lyon to Mainz costing on average $136 (€110).
A bus is $174 (€141) less than a flight for this route with tickets for a flight from Lyon to Mainz costing on average $244 (€197).
The fastest way to travel from Lyon to Mainz is by flight with an average journey time of 1h 25m.
Other travel options to Mainz take longer:
Train takes on average 6h 5m.
Bus takes on average 10h 57m.
It's helpful to compare your options as there are 3 ways to travel between Lyon and Mainz including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Lyon to Mainz among Omio's users.
Take the train. On this route, it beats driving on both time and money.
The journey is about 36m faster (6h 5m by train vs 6h 41m by car) and roughly $47 (€38) cheaper once you factor in fuel and tolls ($136 (€110) vs $183 (€148)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Live departures
Lyon to Mainz train times
The table below shows live departures for Lyon to Mainz trains for tomorrow, Thursday, June 4. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 8:01 AM Lyon | 6h42 | 2:43 PM Mainz | 0 transfersDirect | |
| 9:01 AM Lyon | 6h14 | 3:15 PM Mainz | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Mainz by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Thu
Jun 04
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Journey information
Overview: Train from Lyon to Mainz
France
Germany
Trains from Lyon to Mainz run on average 1 times per day, taking around 6h 5m. Cheap train tickets for this journey start at $69 (€56) but you can travel from only $42 (€34) by bus.
The earliest train runs at 00:02, the last at 17:38. The fastest train covers the 333 miles (536 km) distance in 6h 14m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $42 (€34)
Distance 333 miles (536 km) |
Average train duration 6h 5m |
Cheapest ticket price $69 (€56) |
Trains per day 1 |
Fastest train 6h 14m |
First train 12:02 AM |
Last train 5:38 PM |
Cheapest Month Feb |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Sun |
Least Busy Day Sat |
Best time to book 56 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $42 (€34)
Train companies: TGV, SNCF | TGV INOUI from Lyon to Mainz trainsTGV, SNCF | TGV INOUI trains will get you between Lyon and Mainz from $42 (€34). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
TGV
About
TGV is a high-speed train company based in France. It operates a fleet of modern trains that can reach speeds of up to 320 km/h. The TGV offers a variety of train types, including the TGV Duplex, TGV Lyria, TGV InOui, and TGV OuiGo. Each train type provides different amenities, such as Wi-Fi, power outlets, and comfortable seating. Ticket options include Standard, Flexi, and Prem’s. Onboard facilities feature a bar, restaurant, and luggage storage. Popular TGV routes include Paris to Lyon, Paris to Marseille, and Paris to Lille.
Luggage & cancellation policy
TGV frequency
1 a day
Luggage included
2 pieces of hand luggage and 1 suitcase included in ticket price
Luggage storage
Dedicated luggage areas at end of carriages and overhead racks
Cancellation Policy
According to fare conditions and ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals and bar service, at-seat dining in first class
Seat reservation
Included in first class, optional fee in second class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, and assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket, guide dogs travel free
Quiet zone
SNCF | TGV INOUI
About
SNCF's TGV INOUI is a premium high-speed train service operating across France and to other European cities. Launched in 2017, it aims to provide an enhanced travel experience with greater comfort, connectivity, and services compared to traditional TGV services. TGV INOUI trains offer features like adjustable seats, electrical outlets, fold-down tables, and dedicated luggage spaces. Passengers can enjoy onboard Wi-Fi and access to the TGV INOUI portal for entertainment and journey information. The service also includes a "Bistro TGV INOUI" for dining, with options for online ordering. SNCF is also introducing a new generation of TGV INOUI trains from 2026, which will be more modular, energy-efficient, and 97% recyclable.
Luggage & cancellation policy
Average Duration
6h 43m
Cheapest Price
$203 (€164)
SNCF | TGV INOUI frequency
1 a day
Luggage included
1 hand luggage + 2 pieces of luggage free of charge
Luggage storage
Overhead racks, end of carriages, between seats
Cancellation Policy
Refund conditions depend on ticket type
Refund
Full refund if train canceled
Amenities on board the train
Wifi
Food sold onboard
Restaurant car (not all trains), at-seat service in 1st class, snack bar/cafe
Seat reservation
Second class: Optional, additional fee. First class: Included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, boarding assistance available
Pets
Small pets in carriers: Free. Large dogs: Paid ticket required. Guide dogs: Free
Quiet zone
Complete guide to Mainz
Things to do in Mainz
Discover the best of Mainz — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mainz trip today.
- Recommended
Landesmuseum Mainz
Major state museum with archaeology, medieval art, Roman finds, and changing exhibitions. Strong choice for understanding Mainz and Rhineland-Palatinate history in one visit.
- Recommended
Museum für Antike Schifffahrt
Archaeological museum focused on Roman navigation, best known for its preserved late Roman ships found in Mainz. Compact but distinctive and especially good for Roman-history fans.
- Must visit
Altstadt
Mainz’s old town is the best area for strolling, with historic lanes, squares, churches, and traditional architecture. It is the city’s core walking district and a must for first visits.
- Must visit
Marktplatz
Central market square by the cathedral, surrounded by historic buildings and often lively with events and local activity. A natural starting point for exploring the center.
- Recommended
Augustinerstraße
Charming old-town street known for its handsome facades and pedestrian-friendly atmosphere. Popular for photos and one of the most pleasant streets to walk in Mainz.
- Vegetarian
Spundekäs
A Rheinhessen cheese spread made with cream cheese, quark, paprika, and spices, traditionally served with pretzels. It is a classic Mainz wine tavern snack.
Weck, Worscht un Woi
A famous regional trio of bread roll, sausage, and local wine that symbolizes everyday food culture in Mainz and the surrounding Rheinhessen region.
- Vegetarian
- Gluten-free
Mainzer Handkäs mit Musik
A sour milk cheese served with onions, vinegar, and oil. It is a traditional tavern dish in the Rhine-Main area, often enjoyed with bread and wine.
Steins Traube
An established fine dining restaurant just outside central Mainz, recognized for refined cuisine, polished service, and a long-standing reputation.
Weinstube Hottum
A traditional Mainz wine tavern known for Rheinhessen specialties, local wines, and a cozy, classic Weinstube atmosphere.
Heiliggeist
A well-known restaurant in a historic former hospital building, offering regional German dishes, local wine, and an atmospheric vaulted interior.
Euro
Prices are moderate by German standards. Groceries and casual meals are reasonable, while central hotels and fine dining cost more.
Average meal costs
- Budget
- EUR 8-15 for kebab, bakery, or takeaway.
- Mid-range
- EUR 18-30 per person at a casual restaurant.
- Fine dining
- EUR 60+ per person at upscale restaurants.
- Coffee
- EUR 3-4.50 for a cappuccino or latte.
Tipping culture
Service is usually included, but rounding up is standard. In restaurants, add about 5-10% for good service. Round up taxi fares. Small tips are appreciated in cafes; not expected for counter service.
MVGmeinRad
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 3.40
- Day pass
- EUR 6.60
To the city center
Mainz Hbf, Mainz -> Schillerplatz, Mainz
- Distance
- 1 km
- Travel time
- 5 min
- On buses and trams, ticket purchase is possible at machines; card payment availability depends on the machine, so carry a backup payment method.
- A day pass is usually the best value if you make more than two trips in Mainz during one day.
FAQs: Trains from Lyon to Mainz
Find answers to the most common questions about traveling from Lyon to Mainz by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.
Train ticket prices from Lyon to Mainz can vary. The cheapest ticket starts at $69 (€56), while the average price is around $136 (€110).
The train from Lyon to Mainz runs once a day and takes approximately 6h 14m.
The first train from Lyon to Mainz leaves at 12:02 AM.
The distance by train from Lyon to Mainz is 333 miles (536 km).
The last train from Lyon to Mainz leaves at 5:38 PM.
Yes, there is a high-speed train from Lyon to Mainz.
There is no direct train service currently available from Lyon to Mainz.
Unfortunately, there is no night train available from Lyon to Mainz.
The train station in Lyon that goes to Mainz is Lyon Part Dieu, which connects to Mainz Hbf.
The cheapest way to get from Lyon to Mainz is by bus, with a cost of around $42 (€34).
Yes, the train journey from Lyon to Mainz offers scenic views, particularly as it passes through the picturesque landscapes of the French countryside and the Rhine Valley, known for its charming vineyards and historic castles.
A day trip from Lyon to Mainz is not feasible since the journey takes 6h 14m, with a distance of 333 miles (536 km). The frequency for this route is 1 per day by train.
Two to three days are ideal for exploring Mainz, allowing time to visit its historic sites, such as the Mainz Cathedral and Gutenberg Museum, while enjoying the local cuisine and Rhine River views.
Yes, you can take the train from Lyon to Mainz.
Since both Lyon and Mainz are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Mainz include Cologne, Stuttgart, Heidelberg, Frankfurt am Main, Mannheim.
We recommend using the train as it is the most popular way to get from Lyon to Mainz among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Germany uses the euro (€) as its currency. Travelers generally find it convenient to use cards, especially contactless payments, in cities and larger establishments. However, cash is still widely accepted and sometimes preferred in smaller shops, markets, and rural areas. Carrying some cash is recommended for flexibility.
In Mainz, travelers should be cautious of pickpocketing, especially in crowded areas like train stations and popular tourist spots. Scams involving overcharging in taxis or at markets can occur, so always agree on prices beforehand. It's advisable to stay vigilant in busy places and keep valuables secure to ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Lyon to Mainz
Lyon
Mainz
The major train station for departures in Lyon is Lyon Part Dieu. Find all the information you need to know about services, amenities and connections at Lyon Part Dieu for your trip from Lyon to Mainz.
Amenities at train station
Wifi
Lockers
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Deskinformation
Ticket Office Hours
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
Distance to city center
1 kmWifi
- Free unlimited WiFi.
Lockers
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
Dining
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
Accessibility
- Complimentary personalized care is available.
Hotel
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
Ticket Office
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
Information Desk
- Located in the station's main hall.
Public transit options for Lyon Part Dieu
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
Amenities at train station
WifiParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Fri: 10:00 - 18:00
Distance to city center
1 kmWifi
- Free, unlimited Wi-Fi is available after creating an account and connecting to "CONNECTION."
Dining
- PAUL
Accessibility
- Hearing, mobility, and visual disability assistance. Accessibility available with elevator, ramp or step-free access, barrier-free toilets.
Hotel
- Mercure Lyon Centre Chateau Perrache
- Hotel De Normandie
- InterContinental Lyon-Hotel Dieu
Ticket Office
- Mon - Fri: 10:00 - 18:00
Information Desk
- Information services are available at the ticket office, located in Hall Level 2.
Public transit options for Lyon-Perrache
- Metro lines: A, B, C, D
- Bus lines: 8, 31, 46, 49, 55, 60, 63, S1, C19, C21, C22
- Tram lines: 1, 2
- Train lines: TGV, TGV INOUI, OUIGO, TER Auvergne-Rhône-Alpes, Intercités
The major train station for arrivals in Mainz is Mainz Hbf. Find all the information you need to know about services, amenities and connections at Mainz Hbf for your journey to Mainz from Lyon.
Amenities at train station
WifiLockers
ShoppingParkingDiningATMTaxisAccessibilityWCHotel
Lounge
Lost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
Distance to city center
2 kmDining
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
Hotel
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
Amenities at train station
WifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Distance to city center
1 kmDining
- McDonald's
- Cafe Extrablatt
- Hans im Glück
- The Big Easy
Hotel
- Hyatt Regency Mainz
- Favorite Parkhotel
- Ibis Hotel Mainz City
- Hof Ehrenfels
More options for your journey from Lyon to Mainz
Here are some other resources that might have the information you need
Most popular trains to and from Mainz and Lyon
Most popular train connections to Mainz
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