The cheapest and fastest trains from Lyon to Mainz
Cheapest price
$135
Average price
$255
Fastest journey
6 h 12 m
Average duration
6 h 31 m
Trains per day
3
Distance
536 km
The best way to find a cheap train ticket from Lyon to Mainz is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Mainz will cost around $255 if you buy it on the day, but the cheapest tickets can be found for only $135.
Of the 3 trains that leave Lyon for Mainz on Fri, Dec 05, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Dec 05 the direct trains cover the 536 km distance in an average of 6 h 31 m but if you time it right, some trains will get you there in just 6 h 12 m .
On Fri, Dec 05 the slowest trains will take 6 h 41 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare bus, train, and flight for Lyon to Mainz
Omio recommends booking the train as it is the most popular option from Lyon to Mainz among Omio's users. If you are prioritising price take the bus with prices starting from €30. For those with little time consider booking a flight which can get you there in 1h 47m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €30, and a flight costs an average of €87.
Distance: 333 miles (536 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€137 Average price | €59 Average price Cheapest | €204 Average price |
6h 33m Average total duration 6h 3m Onboard + 30m Additional time* | 11h 30m Average total duration 11h 0m Onboard + 30m Additional time* | 4h 47m Average total duration Fastest 1h 47m Onboard + 3h 0m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 0.5 - 1.3kg CO2 emissions | 1.6 - 3.2kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Lyon to Mainz train times
The table below shows live departures for Lyon to Mainz trains for tomorrow, Friday, December 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:02 AM Lyon | 6h41 | 2:43 PM Mainz | 0 transfersDirect | |
![]() | 8:04 AM Lyon | 6h39 | 2:43 PM Mainz | 0 transfersDirect | |
![]() | 2:04 PM Lyon | 6h12 | 8:16 PM Mainz | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Mainz by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 05
Dec 06
Dec 07
Dec 08
Dec 09
Dec 10
Dec 11
Why should you book Lyon to Mainz trains with Omio?
TGV as well as SNCF and TGV INOUI offer trains services from Lyon to Mainz. Omio is an official ticket reseller for all your travel options from Lyon to Mainz.
Why book with Omio vs TGV?
- Compare with other providers: On Omio, you can not only buy tickets for TGV, but also compare tickets for the likes of SNCF and TGV INOUI to find the best option for your trip from Lyon to Mainz.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare TGV with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Lyon to Mainz.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While TGV tickets can be bought on TGV's website or third party sellers, Omio allows you to compare with the likes of SNCF and TGV INOUI to help you choose the right option for your journey from Lyon to Mainz.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Lyon to Mainz.
Journey information
Overview: Train from Lyon to Mainz
Trains from Lyon to Mainz run on average 1 times per day, taking around 6h 3m. Cheap train tickets for this journey start at $82 (€66) but you can travel from only $37 (€30) by bus.
The earliest train runs at 00:02, the last at 22:25. The fastest train covers the 333 miles (536 km) distance in 6h 11m.
Distance 333 miles (536 km) |
Average train duration 6h 3m |
Cheapest ticket price $82 (€66) |
Trains per day 1 |
Fastest train 6h 11m |
First train 00:02 |
Last train 22:25 |
Train companies: TGV, SNCF, TGV INOUI from Lyon to Mainz trainsTGV, SNCF, TGV INOUI trains will get you between Lyon and Mainz from $37 (€30). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
TGV
TGV INOUI
SNCF
FAQs: Trains from Lyon to Mainz
Find answers to the most common questions about traveling from Lyon to Mainz by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Lyon to Mainz
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Free unlimited WiFi.
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
- Complimentary personalized care is available.
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Located in the station's main hall.
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
- McDonald's
- Cafe Extrablatt
- Hans im Glück
- The Big Easy
- Hyatt Regency Mainz
- Favorite Parkhotel
- Ibis Hotel Mainz City
- Hof Ehrenfels
More options for your journey from Lyon to Mainz
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