The cheapest and fastest buses from Prague to Mainz
Cheapest price
$49
Average price
$52
Fastest journey
8 h 5 m
Average duration
9 h 15 m
Buses per day
2
Distance
439 km
The best way to find a cheap bus ticket from Prague to Mainz is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Mainz will cost around $52 if you buy it on the day, but the cheapest tickets can be found for only $49.
Of the 2 buses that leave Prague for Mainz on Thu, Dec 11, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Dec 11 the direct buses cover the 439 km distance in an average of 9 h 15 m but if you time it right, some buses will get you there in just 8 h 5 m .
On Thu, Dec 11 the slowest buses will take 10 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Prague to Mainz
Omio recommends booking the train as it is the most popular option from Prague to Mainz among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a flight which can get you there in 1h 16m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a flight costs an average of €51.
Distance: 272 miles (439 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€37 Average price Cheapest | €85 Average price | €124 Average price |
7h 29m Average total duration 6h 59m Onboard + 30m Additional time* | 8h 11m Average total duration 7h 41m Onboard + 30m Additional time* | 4h 16m Average total duration Fastest 1h 16m Onboard + 3h 0m Additional time* |
0.4 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.6kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Prague to Mainz Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:50AM | Arrival Time 12:15PM | Duration 8h25 | Departure days Sat | Cheapest price $50 |
Operator FlixBus | Departure Time 04:10AM | Arrival Time 12:15PM | Duration 8h05 | Departure days Sat | Cheapest price $50 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 12:55AM | Duration 10h10 | Departure days Sat | Cheapest price $54 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 12:55AM | Duration 9h55 | Departure days Sat | Cheapest price $54 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 06:40AM | Duration 10h40 | Departure days Sat | Cheapest price $81 |
Operator Regiojet | Departure Time 11:00PM | Arrival Time 05:55AM | Duration 6h55 | Departure days Sat | Cheapest price $48 |
Live departures
Prague to Mainz bus times
The table below shows live departures for Prague to Mainz buses for today, Wednesday, December 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:00 PM Prague | 10h55 | 10:55 PM Mainz | 0 transfersDirect | |
| Thursday, December 11 | |||||
![]() | 2:10 AM Prague | 8h05 | 10:15 AM Mainz | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Mainz by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 11
Dec 12
Dec 13
Dec 14
Dec 15
Dec 16
Dec 17
Journey information
Overview: Bus from Prague to Mainz
Buses from Prague to Mainz run on average 6 times per day, taking around 6h 59m. Cheap bus tickets for this journey start at $31 (€25) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 272 miles (439 km) distance in 6h 55m.
Distance 272 miles (439 km) |
Average bus duration 6h 59m |
Cheapest ticket price $31 (€25) |
Buses per day 6 |
Direct buses 2 |
Fastest bus 6h 55m |
First bus 00:20 |
Last bus 23:55 |
Bus providers: FlixBus, BlaBlaCar from Prague to MainzYou can travel by bus between Prague to Mainz with FlixBus, BlaBlaCar for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from Prague to Mainz
Find answers to the most common questions about traveling from Prague to Mainz by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Prague to Mainz, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Prague to Mainz
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
More options for your journey from Prague to Mainz
Here are some other resources that might have the information you need


