- Must visit
Gutenberg Museum
World-class museum dedicated to Johannes Gutenberg, showcasing early printing, rare books, and working press demonstrations.
Cheapest price
$34
Average price
$40
Fastest journey
6 h 55 m
Average duration
8 h 54 m
Buses per day
6
Distance
439 km
The best way to find a cheap bus ticket from Prague to Mainz is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Mainz will cost around $40 if you buy it on the day, but the cheapest tickets can be found for only $34.
Of the 6 buses that leave Prague for Mainz on Tue, Jul 28, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jul 28 the direct buses cover the 439 km distance in an average of 8 h 54 m but if you time it right, some buses will get you there in just 6 h 55 m .
On Tue, Jul 28 the slowest buses will take 11 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
(Prague -> Amsterdam)
FlixBus · FlixBus
FlixBus · FlixBus
(Prague -> Amsterdam)
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Prague to Mainz among Omio's users. If you are prioritising price take the bus with prices starting from $26. For those with little time consider booking a flight which can get you there in 1h 15m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $26, and a flight costs an average of $71.
Distance: 272 miles (439 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$35 Average price Cheapest | $111 Average price | $144 Average price | $96 Average price (fuel + tolls) |
7h 32m Average total duration 7h 2m Onboard + 30m Additional time* | 8h 2m Average total duration 7h 32m Onboard + 30m Additional time* | 4h 15m Average total duration Fastest 1h 15m Onboard + 3h 0m Additional time* | 5h 11m Average total duration (door-to-door) |
0.4 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.6kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Mainz:
A bus is $76 (€76) less than a train for this route with tickets for a train from Prague to Mainz costing on average $111 (€111).
A bus is $109 (€109) less than a flight for this route with tickets for a flight from Prague to Mainz costing on average $144 (€144).
Other travel options to Mainz take longer:
Bus takes on average 7h 2m.
Train takes on average 7h 32m.
Tickets start at around $35 (€35) compared to roughly $96 (€96) in fuel and tolls — a saving of about $61 (€61). The journey takes 7h 2m versus 5h 11m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:10AM | Arrival Time 10:15AM | Duration 8h05 | Departure days Wed, Thu | Cheapest price $28 |
Operator FlixBus | Departure Time 03:10AM | Arrival Time 11:15AM | Duration 8h05 | Departure days Mon, Thu, Sun | Cheapest price $26 |
Operator FlixBus | Departure Time 03:25AM | Arrival Time 12:00PM | Duration 8h35 | Departure days Tue, Fri, Sat | Cheapest price $34 |
Operator FlixBus | Departure Time 03:40AM | Arrival Time 12:00PM | Duration 8h20 | Departure days Tue, Fri, Sat | Cheapest price $34 |
Operator FlixBus | Departure Time 07:35AM | Arrival Time 07:30PM | Duration 11h55 | Departure days Tue, Fri, Sat | Cheapest price $46 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 07:30PM | Duration 11h35 | Departure days Tue, Fri, Sat | Cheapest price $46 |
Operator RegioJet a.s. | Departure Time 11:00PM | Arrival Time 05:55AM | Duration 6h55 | Departure days Tue, Fri, Sat | Cheapest price $35 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 08:10AM | Duration 9h05 | Departure days Tue, Fri | Cheapest price $44 |
The table below shows live departures for Prague to Mainz buses for today, Monday, July 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:10 AM Prague | 8h05 | 11:15 AM Mainz | 0 transfersDirect | |
| Tuesday, July 28 | |||||
FlixBus | 3:25 AM Prague, Central Train Station | 8h35 | 12:00 PM Mainz, Binger Schlag (Kurzzeitparkplatz) | 0 transfersDirect | |
FlixBus | 3:40 AM Praha, Na Knížecí | 8h20 | 12:00 PM Mainz, Binger Schlag (Kurzzeitparkplatz) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Prague to Mainz run on average 6 times per day, taking around 7h 2m. Cheap bus tickets for this journey start at $26 (€26) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:20, the last at 23:30. The fastest bus covers the 272 miles (439 km) distance in 6h 55m.
Distance 272 miles (439 km) |
Average bus duration 7h 2m |
Cheapest ticket price $26 (€26) |
Buses per day 6 |
Direct buses 3 |
Fastest bus 6h 55m |
First bus 12:20 AM |
Last bus 11:30 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Wed |
Best time to book 49 days |
Discover the best of Mainz — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mainz trip today.
World-class museum dedicated to Johannes Gutenberg, showcasing early printing, rare books, and working press demonstrations.
State museum with art, archaeology, and Roman finds, spanning ancient artifacts to paintings and decorative arts.
Museum on Roman Mainz featuring military, daily life, and stone monuments from the city’s ancient past.
Main market square beside the cathedral, lively with historic façades, weekly markets, and a classic old-town atmosphere.
Picturesque old-town lane lined with half-timbered houses, shops, and a timeless atmosphere loved by local walkers.
Broad Rhine promenade ideal for walks, river views, events, and seeing Mainz’s waterside landmarks in one stretch.
Spundekäs is a creamy cheese spread with paprika, served with pretzels. It is a Rheinhessen wine tavern classic and a staple snack in Mainz.
Weck, Worscht un Woi means bread roll, sausage and wine. It is a simple regional trio closely tied to Mainz tavern culture and local wine drinking.
Handkäs mit Musik is a sour milk cheese marinated with onions and vinegar. It is a beloved Hessian and Rhine-Main tavern dish often enjoyed with bread.
Refined Michelin-starred dining with seasonal tasting menus and polished service in an elegant setting.
Traditional Mainz wine tavern known for regional dishes, local wines and a historic atmosphere near the old town.
Classic brewery restaurant serving Mainz specialties and house beer in a lively, long-established setting.
Moderate for Germany: hotels and dining are mid-priced, while local transit is reasonable for city stays and day trips.
Service is usually included, but rounding up or adding 5-10% is customary. Round up for cafes and taxis, and hand the tip directly when paying.
Official public transport app
Mainz, Binger Schlag (Kurzzeitparkplatz) -> Mainz Hauptbahnhof
Find answers to the most common questions about traveling from Prague to Mainz by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.

Most Prague to Mainz buses use the Praha, Na Knížecí to Mainz, Binger Schlag (Kurzzeitparkplatz) station pair. Use this guide to compare Prague and Mainz bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Here are some other resources that might have the information you need