- Must visit
Gutenberg Museum
One of the world’s most important museums of printing history, dedicated to Johannes Gutenberg and early bookmaking. A flagship Mainz attraction with historic presses and notable Bible displays.
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The cheapest and fastest buses from Prague to Mainz
Showing times and prices for Jun 11
Cheapest price
$33
Average price
$49
Fastest journey
8 h 5 m
Average duration
8 h 5 m
Buses per day
2
Distance
439 km
Cheap tickets
The best way to find a cheap bus ticket from Prague to Mainz is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Mainz will cost around $49 if you buy it on the day, but the cheapest tickets can be found for only $33.
Fast buses
Of the 2 buses that leave Prague for Mainz on Thu, Jun 11, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jun 11 the direct buses cover the 439 km distance in an average of 8 h 5 m but if you time it right, some buses will get you there in just 8 h 5 m .
On Thu, Jun 11 the slowest buses will take 8 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3:10 AM8h05Prague11:15 AMMainz$331One-way0 transfers- 2:10 AM8h05Prague10:15 AMMainz$661One-way0 transfers
- 3:10 AM8h05Prague11:15 AMMainz$331One-way0 transfers
- 2:10 AM8h05Prague10:15 AMMainz$661One-way0 transfers
Travel Information
Compare train, bus, and flight for Prague to Mainz
Omio recommends booking the train as it is the most popular option from Prague to Mainz among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 1h 15m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $87.
Distance: 272 miles (439 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$43 Average price Cheapest | $136 Average price | $177 Average price | $119 Average price (fuel + tolls) |
7h 32m Average total duration 7h 2m Onboard + 30m Additional time* | 8h 2m Average total duration 7h 32m Onboard + 30m Additional time* | 4h 15m Average total duration Fastest 1h 15m Onboard + 3h 0m Additional time* | 5h 11m Average total duration (door-to-door) |
0.4 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.6kg CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Prague to Mainz is a bus with an average price of $43 (€35).
This is compared to other travel options from Prague to Mainz:
A bus is $93 (€76) less than a train for this route with tickets for a train from Prague to Mainz costing on average $136 (€111).
A bus is $134 (€109) less than a flight for this route with tickets for a flight from Prague to Mainz costing on average $177 (€144).
The fastest way to travel from Prague to Mainz is by flight with an average journey time of 1h 15m.
Other travel options to Mainz take longer:
Bus takes on average 7h 2m.
Train takes on average 7h 32m.
It's helpful to compare your options as there are 3 ways to travel between Prague and Mainz including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Prague to Mainz among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $43 (€35) compared to roughly $119 (€96) in fuel and tolls — a saving of about $76 (€61). The journey takes 7h 2m versus 5h 11m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Prague to Mainz Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:10AM | Arrival Time 10:15AM | Duration 8h05 | Departure days Thu, Sat | Cheapest price $55 |
Operator FlixBus | Departure Time 03:10AM | Arrival Time 11:15AM | Duration 8h05 | Departure days Mon, Thu, Fri, Sat | Cheapest price $33 |
Operator FlixBus | Departure Time 03:50AM | Arrival Time 12:15PM | Duration 8h25 | Departure days Tue, Wed, Sun | Cheapest price $34 |
Operator FlixBus | Departure Time 04:10AM | Arrival Time 12:15PM | Duration 8h05 | Departure days Tue, Wed, Sun | Cheapest price $34 |
Operator FlixBus | Departure Time 06:55AM | Arrival Time 05:45PM | Duration 10h50 | Departure days Sat | Cheapest price $48 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 07:30PM | Duration 11h35 | Departure days Tue, Wed, Sun | Cheapest price $41 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 11:55PM | Duration 9h55 | Departure days Sat | Cheapest price $51 |
Operator RegioJet a.s. | Departure Time 11:00PM | Arrival Time 05:55AM | Duration 6h55 | Departure days Tue, Wed, Sun | Cheapest price $32 |
Live departures
Prague to Mainz bus times
The table below shows live departures for Prague to Mainz buses for today, Wednesday, June 10. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus | 3:50 AM Prague, Central Train Station | 8h25 | 12:15 PM Mainz, Binger Schlag (Kurzzeitparkplatz) | 0 transfersDirect | |
| FlixBus | 4:10 AM Praha, Na Knížecí | 8h05 | 12:15 PM Mainz, Binger Schlag (Kurzzeitparkplatz) | 0 transfersDirect | |
| FlixBus · FlixBus | 7:55 AM Praha, Na Knížecí | 11h35 | 7:30 PM Mainz, Binger Schlag (Kurzzeitparkplatz) | 1 transfer | |
 (Prague -> Amsterdam) | 11:00 PM Praha, ÚAN Florenc | 6h55 | 5:55 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Mainz by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Thu
Jun 11
Jun 11
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Jun 12
Sat
Jun 13
Jun 13
Sun
Jun 14
Jun 14
Mon
Jun 15
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Tue
Jun 16
Jun 16
Wed
Jun 17
Jun 17
Why should you book Prague to Mainz buses with Omio?
FlixBus operates all buses services from Prague to Mainz.
Omio is an official ticket reseller for all your travel options from Prague to Mainz.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Mainz.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Mainz.
Journey information
Overview: Bus from Prague to Mainz
Czechia
Germany
Buses from Prague to Mainz run on average 6 times per day, taking around 7h 2m. Cheap bus tickets for this journey start at $32 (€26) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:20, the last at 23:30. The fastest bus covers the 272 miles (439 km) distance in 6h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 272 miles (439 km) |
Average bus duration 7h 2m |
Cheapest ticket price $32 (€26) |
Buses per day 6 |
Direct buses 3 |
Fastest bus 6h 55m |
First bus 12:20 AM |
Last bus 11:30 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Wed |
Best time to book 49 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, BlaBlaCar from Prague to MainzYou can travel by bus between Prague to Mainz with FlixBus, BlaBlaCar for as low as $32 (€26). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
8h 5m
Cheapest Price
$33 (€26)
FlixBus frequency
5 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar
About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: "Bla" for quiet, "BlaBla" for talkative, and "BlaBlaBla" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys.
Luggage & cancellation policy
BlaBlaCar frequency
2 a day
Complete guide to Mainz
Things to do in Mainz
Discover the best of Mainz — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mainz trip today.
- Recommended
Landesmuseum Mainz
Major state museum with archaeology, medieval art, Roman finds, and changing exhibitions. Strong choice for understanding Mainz and Rhineland-Palatinate history in one visit.
- Recommended
Museum für Antike Schifffahrt
Archaeological museum focused on Roman navigation, best known for its preserved late Roman ships found in Mainz. Compact but distinctive and especially good for Roman-history fans.
- Must visit
Altstadt
Mainz’s old town is the best area for strolling, with historic lanes, squares, churches, and traditional architecture. It is the city’s core walking district and a must for first visits.
- Must visit
Marktplatz
Central market square by the cathedral, surrounded by historic buildings and often lively with events and local activity. A natural starting point for exploring the center.
- Recommended
Augustinerstraße
Charming old-town street known for its handsome facades and pedestrian-friendly atmosphere. Popular for photos and one of the most pleasant streets to walk in Mainz.
- Vegetarian
Spundekäs
A Rheinhessen cheese spread made with cream cheese, quark, paprika, and spices, traditionally served with pretzels. It is a classic Mainz wine tavern snack.
Weck, Worscht un Woi
A famous regional trio of bread roll, sausage, and local wine that symbolizes everyday food culture in Mainz and the surrounding Rheinhessen region.
- Vegetarian
- Gluten-free
Mainzer Handkäs mit Musik
A sour milk cheese served with onions, vinegar, and oil. It is a traditional tavern dish in the Rhine-Main area, often enjoyed with bread and wine.
Steins Traube
An established fine dining restaurant just outside central Mainz, recognized for refined cuisine, polished service, and a long-standing reputation.
Weinstube Hottum
A traditional Mainz wine tavern known for Rheinhessen specialties, local wines, and a cozy, classic Weinstube atmosphere.
Heiliggeist
A well-known restaurant in a historic former hospital building, offering regional German dishes, local wine, and an atmospheric vaulted interior.
Euro
Prices are moderate by German standards. Groceries and casual meals are reasonable, while central hotels and fine dining cost more.
Average meal costs
- Budget
- EUR 8-15 for kebab, bakery, or takeaway.
- Mid-range
- EUR 18-30 per person at a casual restaurant.
- Fine dining
- EUR 60+ per person at upscale restaurants.
- Coffee
- EUR 3-4.50 for a cappuccino or latte.
Tipping culture
Service is usually included, but rounding up is standard. In restaurants, add about 5-10% for good service. Round up taxi fares. Small tips are appreciated in cafes; not expected for counter service.
DB Navigator
Get the appOfficial public transport app
Prices
- Single ticket
- 3.40 EUR
- Day pass
- 6.50 EUR
To the city center
Mainz, Binger Schlag (Kurzzeitparkplatz), Mainz -> Mainz Hauptbahnhof, Mainz
- Distance
- 1 km
- Travel time
- 12 min
- RMV tickets are valid across buses, trams, and local trains within the purchased fare zone. Buy tickets in the RMVgo app, at machines, or from sales points.
- Card payment is commonly available in the app and at many ticket machines, but not always on board buses. Buy your ticket before boarding when possible.
FAQs: Bus from Prague to Mainz
Find answers to the most common questions about traveling from Prague to Mainz by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Prague to Mainz can start from as little as $32 (€26) when you book in advance. The average bus ticket price for Prague to Mainz is $43 (€35) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Prague to Mainz is 6h 55m to travel the 272 miles (439 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Prague to Mainz leaves at 12:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Prague to Mainz leaves at 11:30 PM.
Yes, there are 3 direct buses a day from Prague to Mainz with FlixBus, BlaBlaCar. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Prague to Mainz, you can count on FlixBus, BlaBlaCar for the best way to get you to Mainz. You can also check all possible bus companies who offer a service between Prague and Mainz and compare the amenities they offer before buying a bus ticket.
A trip to Mainz from Prague is worth doing but not as a day trip with a journey time of 6h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Prague to Mainz is September.
It's helpful to compare your options as there are 3 ways to travel between Prague and Mainz including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Prague to Mainz:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Prague to Mainz for bus company FlixBus.
Whether you can cancel your bus ticket from Prague to Mainz depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Prague to Mainz.
Yes, the following luggage options are included when booking a bus ticket from Prague to Mainz:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Prague to Mainz:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Prague to Mainz. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Prague to Mainz with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Prague to Mainz with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Prague to Mainz with the following bus company: FlixBus.
Since both Prague and Mainz are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the train as it is the most popular way to get from Prague to Mainz among Omio's users.
Germany uses the euro (€) as its currency. Travelers generally find it convenient to use cards, especially contactless payments, in cities and larger establishments. However, cash is still widely accepted and sometimes preferred in smaller shops, markets, and rural areas. Carrying some cash is recommended for flexibility.
In Mainz, travelers should be cautious of pickpocketing, especially in crowded areas like train stations and popular tourist spots. Scams involving overcharging in taxis or at markets can occur, so always agree on prices beforehand. It's advisable to stay vigilant in busy places and keep valuables secure to ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Prague to Mainz
Prague
Mainz
The major bus station for departures in Prague is Praha, ÚAN Florenc. Find all the information you need to know about services, amenities and connections at Praha, ÚAN Florenc for your trip from Prague to Mainz.
Amenities at bus station
Wifi
Parking
Dining
ATM
Taxis
Accessibility
WC
Ticket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 km
Car connection
KřižíkovaWifi
- Free Wi-Fi
Dining
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, ÚAN Florenc
- Bus: 133, 135, 175, 207 Metro: B, C
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCinformation
Distance to city center
2 kmCar connection
OstrovskéhoWifi
- Free Wi-Fi
Dining
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Na Knížecí
- Bus: 137, 176, 191 Metro: B
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 00:00-23:59
Distance to city center
1 kmCar connection
WilsonovaWifi
- Free Wi-Fi
Dining
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Hlavní Nádraží
- Bus: 135, 175, 207 Metro: C Train: All major s
The major bus station for arrivals in Mainz is Mainz, Binger Schlag (Kurzzeitparkplatz). Find all the information you need to know about services, amenities and connections at Mainz, Binger Schlag (Kurzzeitparkplatz) for your trip to Mainz from Prague.
Mainz, Binger Schlag (Kurzzeitparkplatz)
information
More options for your journey from Prague to Mainz
Here are some other resources that might have the information you need
Most popular buses to and from Mainz and Prague
Most popular bus connections to Mainz
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