- Must visit
Gutenberg Museum
World-class museum dedicated to Johannes Gutenberg, showcasing early printing, rare books, and working press demonstrations.
The best way to find a cheap flight ticket from Prague to Mainz is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Mainz will cost around €127 if you buy it on the day, but the cheapest tickets can be found for only €85.
On Wed, Nov 04, we found 9 flights from Prague to Mainz, including 9 direct services.
On Wed, Nov 04 the direct flights cover the 439 km distance in an average of 2 h 44 m but if you time it right, some flights will get you there in just 1 h .
On Wed, Nov 04 the longest flights will take 6 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||
Flights from Prague to Mainz depart on average 67 times per day, taking around 2h 52m. Cheap flight tickets for this journey start at €65 but you can travel from only €28 by bus.
There are 8 flights per day. The earliest flight runs at 05:05, the last at 22:15. The fastest flight covers the 272 miles (439 km) distance in 50m. August is the cheapest month to fly.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Prague to Mainz.
The table below shows live departures for Prague to Mainz flights for today, Tuesday, November 3. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:55 AM Prague | 6h00 | 1:55 PM Mainz | 0 transfersDirect | |
![]() | 9:50 AM Prague | 3h45 | 1:35 PM Mainz | 0 transfersDirect | |
![]() | 10:00 AM Prague | 1h00 | 11:00 AM Mainz | 0 transfersDirect | |
![]() | 10:40 AM Prague | 1h00 | 11:40 AM Mainz | 0 transfersDirect | |
![]() | 3:55 PM Prague | 1h00 | 4:55 PM Mainz | 0 transfersDirect | |
![]() | 5:00 PM Prague | 15h35 | 8:35 AM Mainz | 0 transfersDirect | |
![]() | 6:35 PM Prague | 26h35 | 9:10 PM Mainz | 0 transfersDirect | |
| Wednesday, November 4 | |||||
![]() | 5:10 AM Prague | 9h20 | 2:30 PM Mainz | 0 transfersDirect | |
![]() | 6:50 AM Prague | 8h25 | 3:15 PM Mainz | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Flights from Prague to Mainz with Lufthansa, KLM, and Lot Polish Airlines. Flights with a stop available on this route with Lufthansa, KLM, and Lot Polish Airlines. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Mainz — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mainz trip today.
World-class museum dedicated to Johannes Gutenberg, showcasing early printing, rare books, and working press demonstrations.
State museum with art, archaeology, and Roman finds, spanning ancient artifacts to paintings and decorative arts.
Museum on Roman Mainz featuring military, daily life, and stone monuments from the city’s ancient past.
Main market square beside the cathedral, lively with historic façades, weekly markets, and a classic old-town atmosphere.
Picturesque old-town lane lined with half-timbered houses, shops, and a timeless atmosphere loved by local walkers.
Broad Rhine promenade ideal for walks, river views, events, and seeing Mainz’s waterside landmarks in one stretch.
Spundekäs is a creamy cheese spread with paprika, served with pretzels. It is a Rheinhessen wine tavern classic and a staple snack in Mainz.
Weck, Worscht un Woi means bread roll, sausage and wine. It is a simple regional trio closely tied to Mainz tavern culture and local wine drinking.
Handkäs mit Musik is a sour milk cheese marinated with onions and vinegar. It is a beloved Hessian and Rhine-Main tavern dish often enjoyed with bread.
Refined Michelin-starred dining with seasonal tasting menus and polished service in an elegant setting.
Traditional Mainz wine tavern known for regional dishes, local wines and a historic atmosphere near the old town.
Classic brewery restaurant serving Mainz specialties and house beer in a lively, long-established setting.
Moderate for Germany: hotels and dining are mid-priced, while local transit is reasonable for city stays and day trips.
Service is usually included, but rounding up or adding 5-10% is customary. Round up for cafes and taxis, and hand the tip directly when paying.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Mainz.
Find answers to the most common questions about traveling from Prague to Mainz by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.

Most Prague to Mainz flights use the Prague Vaclav Havel Airport to airport pair. Use this guide to compare Prague and Mainz airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Prague Vaclav Havel Airport is 11 km from Prague city centre. Public transport options include:
Prague Vaclav Havel Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in Terminals 1 and 2.
Lost and found is available at the station.
Available at Prague Vaclav Havel Airport: Parking, Taxis, WC.
Accessibility facilities are available at Prague Vaclav Havel Airport: Ramps, assistance.