Travel Information
Compare bus, train, and flight for Prague to Mainz
Omio recommends booking the train as it is the most popular option from Prague to Mainz among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 1h 13m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $101.
Distance: 272 miles (439 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$109 Average price | $45 Average price Cheapest | $158 Average price | $121 Average price (fuel + tolls) |
8h 12m Average total duration 7h 42m Onboard + 30m Additional time* | 7h 29m Average total duration 6h 59m Onboard + 30m Additional time* | 4h 13m Average total duration Fastest 1h 13m Onboard + 3h 0m Additional time* | 5h 11m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Mainz:
A bus is $65 (€52) less than a train for this route with tickets for a train from Prague to Mainz costing on average $109 (€87).
A bus is $113 (€90) less than a flight for this route with tickets for a flight from Prague to Mainz costing on average $158 (€126).
Other travel options to Mainz take longer:
Bus takes on average 6h 59m.
Train takes on average 7h 42m.
Travel optionsfrom Prague to Mainz
How to get from Prague to Mainz by train, bus or flight.
Our recommendation
The best way to travel from Prague to Mainz is by taking a bus because it’s the best combination of price and speed.
3:10 AM8h05Prague11:15 AMMainz$421One-way0 transfers
Cheapest
3:10 AM8h05Prague11:15 AMMainz$421One-way0 transfers
Fastest
3:10 AM8h05Prague11:15 AMMainz$421One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Prague to Mainz
Travel to Mainz easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Mainz.

This is compared to other travel options from Prague to Mainz:
A bus is $65 (€52) less than a train for this route with tickets for a train from Prague to Mainz costing on average $109 (€87).
A bus is $113 (€90) less than a flight for this route with tickets for a flight from Prague to Mainz costing on average $158 (€126).
Other travel options to Mainz take longer:
Bus takes on average 6h 59m.
Train takes on average 7h 42m.
- Around 78 flights per day.
- Around 8 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Prague and Mainz as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Mainz Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Mainz, Binger Schlag (Kurzzeitparkplatz).
- Travel with Deutsche Bahn to go to Mainz by train.
- Travel with Lufthansa, Air Dolomiti to go to Mainz by flight.
- Travel with FlixBus, BlaBlaCar to go to Mainz by bus.
- 9 direct flights per day with Lufthansa, Air Dolomiti.
- 3 direct buses per day with FlixBus, BlaBlaCar.
Travelling from Prague to Mainz: related information
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