- Must visit
Uffizi Gallery
World-famous gallery with Botticelli, Leonardo, and Michelangelo. Essential for understanding Renaissance painting and one of Florence’s top visits.
Cheapest price on Sep 19
$49
Average ticket price on Sep 19
$85
Fastest journey on Sep 19
4 h 47 m
Average journey duration on Sep 19
4 h 58 m
Trains on Sep 19
49
Distance
350 km
The best way to find a cheap train ticket from Domodossola to Florence is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Domodossola to Florence will cost around $85 if you buy it on the day, but the cheapest tickets can be found for only $49.
It's difficult to get from Domodossola to Florence without transferring at least 2 times.
Regionale 11417 · Regionale Veloce 3097 · Regionale 18393
Autobus TRENORD 4431A · Regionale TRENORD 2431+
Intercity 599
Autobus TRENORD 4407A · Regionale TRENORD 2407+
9951
Autobus TRENORD 4431A · Regionale TRENORD 2431+
9959
Autobus TRENORD 4415A · Regionale TRENORD 2415+
9931
Regionale 11415 · Regionale Veloce 2015+
FRECCIAROSSA 9583
Autobus TRENORD 4411A · Regionale TRENORD 2411+
FRECCIAROSSA 9515
Autobus TRENORD 4437A · Regionale TRENORD 2437+
FRECCIAROSSA 9567
Autobus TRENORD 4431A · Regionale TRENORD 2431+
FRECCIAROSSA 9555
Autobus TRENORD 4417A · Regionale TRENORD 2417+
FRECCIAROSSA 9527Omio recommends booking the train as it is the most popular option from Domodossola to Florence among Omio's users. If you are prioritising price, take the train, with an average ticket price of $30 For those with little time, consider booking a train, which has an average total journey time of 4h 47m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a train costs an average of $30, while a flight costs an average of $368.
Distance: 217 miles (350 km)
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$30 Average price Cheapest | $368 Average price | $128 Average price (fuel + tolls) | |
4h 47m Average total duration Fastest 4h 17m Onboard + 30m Additional time* | 5h 3m Average total duration 3h 3m Onboard + 2h 0m Additional time* | 4h 37m Average total duration (door-to-door) | |
0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions | 0.3 - 0.9kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Domodossola to Florence:
A train is $338 less than a flight for this route with tickets for a flight from Domodossola to Florence costing on average $368.
Other travel options to Florence take longer:
Train takes on average 4h 17m.
The journey is about 20m faster (4h 17m by train vs 4h 37m by car) and roughly $98 cheaper once you factor in fuel and tolls ($30 vs $128). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Domodossola to Florence trains for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Autobus TRENORD 4411A · Regionale TRENORD 2411+ FRECCIAROSSA 9515 | 4:03 AM Domodossola station | 5h01 | 9:04 AM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4411A · Regionale TRENORD 2411+ 9923 | 4:03 AM Domodossola station | 7h32 | 11:35 AM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4411A · Regionale TRENORD 2411+ 9917 | 4:03 AM Domodossola station | 5h32 | 9:35 AM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4411A · Regionale TRENORD 2411+ 8947 | 4:03 AM Domodossola station | 6h32 | 10:35 AM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4413A · Regionale TRENORD 2413+ FRECCIAROSSA 9519 | 5:03 AM Domodossola station | 5h01 | 10:04 AM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4413A · Regionale TRENORD 2413+ 9923 | 5:03 AM Domodossola station | 6h32 | 11:35 AM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4413A · Regionale TRENORD 2413+ 8947 | 5:03 AM Domodossola station | 5h32 | 10:35 AM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4413A · Regionale TRENORD 2413+ 9931 | 5:03 AM Domodossola station | 8h32 | 1:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4225A · Regionale 10215+ FRECCIAROSSA 9391 | 5:15 AM Domodossola station | 5h35 | 10:50 AM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4225A · Regionale 10215 · Regionale TRENORD 2415+ 9931 | 5:15 AM Domodossola station | 8h20 | 1:35 PM Florence Santa Maria Novella | 3 transfers | |
Autobus TRENORD 4225A · Regionale 10215 · Regionale TRENORD 2415+ 9923 | 5:15 AM Domodossola station | 6h20 | 11:35 AM Florence Santa Maria Novella | 3 transfers | |
Autobus TRENORD 4225A · Regionale 10215 · Regionale TRENORD 2415+ 9935 | 5:15 AM Domodossola station | 9h20 | 2:35 PM Florence Santa Maria Novella | 3 transfers | |
Autobus TRENORD 4415A · Regionale TRENORD 2415+ 9923 | 5:53 AM Domodossola station | 5h42 | 11:35 AM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4415A · Regionale TRENORD 2415+ 9931 | 5:53 AM Domodossola station | 7h42 | 1:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4415A · Regionale TRENORD 2415+ 9935 | 5:53 AM Domodossola station | 8h42 | 2:35 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11415 · Regionale Veloce 2015+ 9931 | 6:17 AM Domodossola station | 7h18 | 1:35 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11415 · Regionale Veloce 2015+ FRECCIAROSSA 9583 | 6:17 AM Domodossola station | 4h47 | 11:04 AM Florence Santa Maria Novella | 2 transfers | |
Regionale 11415 · Regionale Veloce 2015+ 9923 | 6:17 AM Domodossola station | 5h18 | 11:35 AM Florence Santa Maria Novella | 2 transfers | |
Regionale 11415 · Regionale Veloce 2015+ 9935 | 6:17 AM Domodossola station | 8h18 | 2:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4217A · Regionale 10217+ FRECCIAROSSA 9311 | 6:33 AM Domodossola station | 5h17 | 11:50 AM Florence Santa Maria Novella | 2 transfers | |
Regionale 11417 · Regionale Veloce 3097 · Regionale 18393 | 6:48 AM Domodossola station | 9h20 | 4:08 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4417A · Regionale TRENORD 2417+ FRECCIAROSSA 9527 | 7:03 AM Domodossola station | 5h01 | 12:04 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4417A · Regionale TRENORD 2417+ 9931 | 7:03 AM Domodossola station | 6h32 | 1:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4417A · Regionale TRENORD 2417+ 9935 | 7:03 AM Domodossola station | 7h32 | 2:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4417A · Regionale TRENORD 2417+ 9939 | 7:03 AM Domodossola station | 8h32 | 3:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4419A · Regionale TRENORD 2419+ 9931 | 8:03 AM Domodossola station | 5h32 | 1:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4419A · Regionale TRENORD 2419+ 9935 | 8:03 AM Domodossola station | 6h32 | 2:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4419A · Regionale TRENORD 2419+ 9939 | 8:03 AM Domodossola station | 7h32 | 3:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4207A · Regionale 10207+ FRECCIAROSSA 9321 | 11:21 AM Domodossola station | 5h29 | 4:50 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4407A · Regionale TRENORD 2407+ FRECCIAROSSA 9547 | 12:03 PM Domodossola station | 5h01 | 5:04 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4407A · Regionale TRENORD 2407+ 9951 | 12:03 PM Domodossola station | 6h32 | 6:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4407A · Regionale TRENORD 2407+ 9947 | 12:03 PM Domodossola station | 5h32 | 5:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4407A · Regionale TRENORD 2407+ 9955 | 12:03 PM Domodossola station | 7h32 | 7:35 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11427 · Regionale Veloce 2029+ 9959 | 12:45 PM Domodossola station | 7h50 | 8:35 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11427 · Regionale Veloce 2029+ 9951 | 12:45 PM Domodossola station | 5h50 | 6:35 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11427 · Regionale Veloce 2029+ 9955 | 12:45 PM Domodossola station | 6h50 | 7:35 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11427 · Regionale Veloce 2029+ FRECCIAROSSA 9551 | 12:45 PM Domodossola station | 5h19 | 6:04 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ Intercity 599 | 2:03 PM Domodossola station | 7h19 | 9:22 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ FRECCIAROSSA 9555 | 2:03 PM Domodossola station | 5h01 | 7:04 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ 9959 | 2:03 PM Domodossola station | 6h32 | 8:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ 9955 | 2:03 PM Domodossola station | 5h32 | 7:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ 9961 | 2:03 PM Domodossola station | 7h32 | 9:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4433A · Regionale TRENORD 2433+ 9963 | 3:03 PM Domodossola station | 7h32 | 10:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4433A · Regionale TRENORD 2433+ 9959 | 3:03 PM Domodossola station | 5h32 | 8:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4433A · Regionale TRENORD 2433+ 9961 | 3:03 PM Domodossola station | 6h32 | 9:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4435A · Regionale TRENORD 2435+ 9963 | 4:03 PM Domodossola station | 6h32 | 10:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4435A · Regionale TRENORD 2435+ 9961 | 4:03 PM Domodossola station | 5h32 | 9:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4437A · Regionale TRENORD 2437+ FRECCIAROSSA 9567 | 5:03 PM Domodossola station | 5h01 | 10:04 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4437A · Regionale TRENORD 2437+ 9963 | 5:03 PM Domodossola station | 5h32 | 10:35 PM Florence Santa Maria Novella | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, flight, and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Domodossola to Florence run on average 27 times per day, taking around 4h 17m. Cheap train tickets for this journey start at $13 if you book in advance.
The earliest train runs at 00:40, the last at 18:56. The fastest train covers the 217 miles (350 km) distance in 3h 20m.
Distance 217 miles (350 km) |
Average train duration 4h 17m |
Cheapest ticket price $13 |
Trains per day 27 |
Fastest train 3h 20m |
First train 12:40 AM |
Last train 6:56 PM |
Cheapest Month Mar |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Wed |
Best time to book 84 days |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
World-famous gallery with Botticelli, Leonardo, and Michelangelo. Essential for understanding Renaissance painting and one of Florence’s top visits.
Houses Michelangelo’s David alongside major Renaissance sculptures. A must for first-time visitors interested in Florence’s artistic legacy.
Monastic museum with Fra Angelico frescoes and tranquil cells. Ideal for experiencing spiritual art in one of Florence’s most atmospheric spaces.
Florence’s monumental main square, framed by civic buildings and sculpture. A must for first impressions, history, and lively urban atmosphere.
The cathedral square is Florence’s ceremonial heart, surrounded by the Duomo, Baptistery, and bell tower. Essential for architecture lovers.
Riverside viewpoint with one of Florence’s classic panoramas. Best at sunset for sweeping views over the Arno, domes, and historic center.
Thick Florentine T-bone steak from Chianina beef, grilled rare over coals. It is the city's signature celebratory dish and a classic of Tuscan cuisine.
A rustic Tuscan bread soup with black cabbage, cannellini beans, vegetables, and olive oil. A beloved frugal dish rooted in Florentine home cooking.
A thick soup of bread, tomatoes, basil, garlic, and olive oil, served warm or at room temperature. It celebrates simple Tuscan ingredients and stale bread.
Three-Michelin-star fine dining by Enoteca Pinchiorri, known for refined Italian cuisine and an exceptional wine cellar. Elegant and formal.
Legendary casual stop for Lampredotto sandwiches and other tripe specialties. Simple, authentic street food experience in central Florence.
Historic steakhouse famed for Bistecca Alla Fiorentina and classic Tuscan dishes. Traditional, bustling atmosphere near Santa Croce.
Moderate for Italy: hotels in the center are pricier, but dining and transit are reasonable versus Rome or Venice.
Service is often included. Round up or leave €1-2 at cafés, 5-10% for great restaurant service, and round up taxi fares.
Official public transport app
Firenze Santa Maria Novella -> Piazza del Duomo, Florence
Find answers to the most common questions about traveling from Domodossola to Florence by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

Most Domodossola to Florence trains use the Domodossola to Firenze Santa Maria Novella station pair, with some services arriving at Firenze Rifredi. Use this guide to compare Domodossola and Florence train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Domodossola has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Ristorante La Meridiana, Osteria Vecchio Borgo
Free. ATMs are available in the train station.
Ticket office support is available at Domodossola. Information desks are located in the main hall.
Luggage storage is available at Domodossola. Lost and found is available at the station.
Available at Domodossola: Parking, Taxis, WC.
Available at Domodossola: Bike Parking, Car Rental.
Accessibility facilities are available at Domodossola: Elevators, ramps.
Nearby hotels include Hotel Corona, Hotel Ristorante Eurossola, Hotel Domodossola.
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
Firenze Rifredi is 3 km from Florence city centre. Public transport options include:
Firenze Rifredi has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Information Desk, and Luggage Carts.
Food options include: Trattoria Fratelli Briganti, Osteria di Poneta
Free.
Ticket office support is available at Firenze Rifredi. Information desks are located in the main hall.
Luggage storage is available at Firenze Rifredi. Lost and found is available at the station.
Available at Firenze Rifredi: Parking, Taxis, WC.
Available at Firenze Rifredi: Bike Parking, Bike Rental.
Accessibility facilities are available at Firenze Rifredi: Elevators, ramps, restrooms.
Nearby hotels include Hotel Raffaello, Hotel Corolle, Hotel Dalmazia.
Firenze Campo di Marte is 2 km from Florence city centre. Public transport options include:
Firenze Campo di Marte has practical services for this route, including Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, and Bike Rental.
Food options include: Moka Café
The ticket office is open Mon - Sun: 07:15 - 20:45.
Available at Firenze Campo di Marte: Taxis, WC.
Available at Firenze Campo di Marte: Bike Parking, Bike Rental.
Accessibility facilities are available at Firenze Campo di Marte: The station is fully accessible, with step-free access throughout the station.
Nearby hotels include Florence Stadium B&B, Hotel Villa Liana, Hotel della Robbia.
Here are some other resources that might have the information you need