The cheapest and fastest trains from Domodossola station to Florence Santa Maria Novella
Cheapest price
$42
Average price
$84
Fastest journey
4 h 9 m
Average duration
4 h 9 m
Trains per day
43
Distance
349 km
The best way to find a cheap train ticket from Domodossola station to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Domodossola station to Florence Santa Maria Novella will cost around $84 if you buy it on the day, but the cheapest tickets can be found for only $42.
It's difficult to get from Domodossola station to Florence Santa Maria Novella without transferring at least once.
Regionale TRENORD 2431 · Regionale Veloce TTPER 2475 · Regionale 178512:55 PM7h15Domodossola station10:10 PMFlorence Santa Maria Novella$421One-way2 transfers
Regionale TRENORD 2411 · Regionale 2293 · Regionale 182884:55 AM8h13Domodossola station1:08 PMFlorence Santa Maria Novella$481One-way2 transfers
Regionale TRENORD 2413+
99235:55 AM5h40Domodossola station11:35 AMFlorence Santa Maria Novella$631One-way1 transfer
Regionale TRENORD 2439+
FRECCIAROSSA 95736:55 PM4h19Domodossola station11:14 PMFlorence Santa Maria Novella$841One-way1 transfer
Regionale TRENORD 2433+
99613:55 PM5h40Domodossola station9:35 PMFlorence Santa Maria Novella$851One-way1 transfer
Regionale TRENORD 2417+
FRECCIAROSSA 95277:55 AM4h09Domodossola station12:04 PMFlorence Santa Maria Novella$901One-way1 transfer
Regionale TRENORD 2413+
FRECCIAROSSA 95195:55 AM4h09Domodossola station10:04 AMFlorence Santa Maria Novella$901One-way1 transfer
Regionale TRENORD 2435+
FRECCIAROSSA 95634:55 PM4h09Domodossola station9:04 PMFlorence Santa Maria Novella$901One-way1 transfer
Regionale TRENORD 2437+
FRECCIAROSSA 95675:55 PM4h09Domodossola station10:04 PMFlorence Santa Maria Novella$901One-way1 transfer
Regionale TRENORD 2433+
FRECCIAROSSA 95593:55 PM4h09Domodossola station8:04 PMFlorence Santa Maria Novella$901One-way1 transfer
Travel Information
Compare train, bus, and flight for Domodossola station to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Domodossola station to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the train with prices starting from $30. For those with little time consider booking a bus which can get you there in 4h 17m. The ticket price range depends on the travel mode: a train costs an average of $30, and a flight costs an average of $195.
Distance: 216 miles (349 km)
Compare train with
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$43 Average price Cheapest | $240 Average price | $96 Average price | $131 Average price (fuel + tolls) |
5h 5m Average total duration 4h 35m Onboard + 30m Additional time* | 8h 25m Average total duration 5h 25m Onboard + 3h 0m Additional time* | 4h 47m Average total duration Fastest 4h 17m Onboard + 30m Additional time* | 4h 15m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Domodossola station to Florence Santa Maria Novella:
A train is $53 (€43) less than a bus for this route with tickets for a bus from Domodossola station to Florence Santa Maria Novella costing on average $96 (€77).
A train is $197 (€158) less than a flight for this route with tickets for a flight from Domodossola station to Florence Santa Maria Novella costing on average $240 (€193).
Other travel options to Florence Santa Maria Novella take longer:
Train takes on average 4h 35m.
Flight takes on average 5h 25m.
Tickets start at around $43 (€34) compared to roughly $131 (€105) in fuel and tolls — a saving of about $88 (€71). The journey takes 4h 35m versus 4h 15m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Domodossola station to Florence Santa Maria Novella train times
The table below shows live departures for Domodossola station to Florence Santa Maria Novella trains for tomorrow, Friday, August 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale TRENORD 2411 · Regionale 2293 · Regionale 18288 | 4:55 AM Domodossola station | 8h13 | 1:08 PM Florence Santa Maria Novella | 2 transfers | |
Regionale TRENORD 2411+ FRECCIAROSSA 9515 | 4:55 AM Domodossola station | 4h09 | 9:04 AM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2411+ 9917 | 4:55 AM Domodossola station | 4h40 | 9:35 AM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2411+ 8947 | 4:55 AM Domodossola station | 5h40 | 10:35 AM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2411+ 9927 | 4:55 AM Domodossola station | 7h40 | 12:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2413+ FRECCIAROSSA 9519 | 5:55 AM Domodossola station | 4h09 | 10:04 AM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2413+ 9923 | 5:55 AM Domodossola station | 5h40 | 11:35 AM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2413+ 8947 | 5:55 AM Domodossola station | 4h40 | 10:35 AM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2413+ 9927 | 5:55 AM Domodossola station | 6h40 | 12:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2413+ 9931 | 5:55 AM Domodossola station | 7h40 | 1:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2415+ FRECCIAROSSA 9583 | 6:53 AM Domodossola station | 4h11 | 11:04 AM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2415+ 9923 | 6:53 AM Domodossola station | 4h42 | 11:35 AM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2415+ 9927 | 6:53 AM Domodossola station | 5h42 | 12:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2415+ 9931 | 6:53 AM Domodossola station | 6h42 | 1:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 10217+ FRECCIAROSSA 9311 | 7:25 AM Domodossola station | 4h25 | 11:50 AM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2417+ FRECCIAROSSA 9527 | 7:55 AM Domodossola station | 4h09 | 12:04 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2417+ 9927 | 7:55 AM Domodossola station | 4h40 | 12:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2417+ 9931 | 7:55 AM Domodossola station | 5h40 | 1:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2417+ 9939 | 7:55 AM Domodossola station | 7h40 | 3:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2419+ 8143 | 8:55 AM Domodossola station | 7h40 | 4:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2419+ 9931 | 8:55 AM Domodossola station | 4h40 | 1:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2419+ 9939 | 8:55 AM Domodossola station | 6h40 | 3:35 PM Florence Santa Maria Novella | 1 transfer | |
Autobus TRENORD 2427A · Regionale TRENORD 2427+ FRECCIAROSSA 9547 | 12:10 PM Domodossola station | 4h54 | 5:04 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 2427A · Regionale TRENORD 2427+ 9947 | 12:10 PM Domodossola station | 5h25 | 5:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 2427A · Regionale TRENORD 2427+ 9951 | 12:10 PM Domodossola station | 6h25 | 6:35 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 2427A · Regionale TRENORD 2427+ 9955 | 12:10 PM Domodossola station | 7h25 | 7:35 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11427 · Regionale Veloce 2029+ FRECCIAROSSA 9325 | 12:45 PM Domodossola station | 6h05 | 6:50 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11427 · Regionale Veloce 2029+ 9951 | 12:45 PM Domodossola station | 5h50 | 6:35 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11427 · Regionale Veloce 2029+ 9955 | 12:45 PM Domodossola station | 6h50 | 7:35 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11427 · Regionale Veloce 2029+ 9959 | 12:45 PM Domodossola station | 7h50 | 8:35 PM Florence Santa Maria Novella | 2 transfers | |
Regionale TRENORD 2431 · Regionale Veloce TTPER 2475 · Regionale 17851 | 2:55 PM Domodossola station | 7h15 | 10:10 PM Florence Santa Maria Novella | 2 transfers | |
Regionale TRENORD 2431+ 9955 | 2:55 PM Domodossola station | 4h40 | 7:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2431+ 9959 | 2:55 PM Domodossola station | 5h40 | 8:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2431+ FRECCIAROSSA 9555 | 2:55 PM Domodossola station | 4h09 | 7:04 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2431+ 9961 | 2:55 PM Domodossola station | 6h40 | 9:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2433+ 9961 | 3:55 PM Domodossola station | 5h40 | 9:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2433+ FRECCIAROSSA 9559 | 3:55 PM Domodossola station | 4h09 | 8:04 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2433+ 9959 | 3:55 PM Domodossola station | 4h40 | 8:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 10235+ FRECCIAROSSA 9329 | 4:06 PM Domodossola station | 4h44 | 8:50 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2435+ FRECCIAROSSA 9563 | 4:55 PM Domodossola station | 4h09 | 9:04 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2435+ 9961 | 4:55 PM Domodossola station | 4h40 | 9:35 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2437+ FRECCIAROSSA 9567 | 5:55 PM Domodossola station | 4h09 | 10:04 PM Florence Santa Maria Novella | 1 transfer | |
Regionale TRENORD 2439+ FRECCIAROSSA 9573 | 6:55 PM Domodossola station | 4h19 | 11:14 PM Florence Santa Maria Novella | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Domodossola station to Florence Santa Maria Novella by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 21
Aug 22
Aug 23
Aug 24
Aug 25
Aug 26
Aug 27
Why should you book Domodossola station to Florence Santa Maria Novella trains with Omio?
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Italo, Regionale, Intercity or Trenitalia to find the best option for your trip from Domodossola station to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Domodossola station to Florence Santa Maria Novella.
Why book with Omio over Raileurope or Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Italo, Regionale, Intercity or Trenitalia to find the best option for your trip from Domodossola station to Florence Santa Maria Novella.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Domodossola station to Florence Santa Maria Novella.
Journey information
Overview: Train from Domodossola station to Florence Santa Maria Novella
Trains from Domodossola station to Florence Santa Maria Novella run on average 12 times per day, taking around 4h 35m. Cheap train tickets for this journey start at $30 (€24) if you book in advance.
The earliest train runs at 11:43, the last at 15:56. The fastest train covers the 216 miles (349 km) distance in 4h 8m.
Distance 216 miles (349 km) |
Average train duration 4h 35m |
Cheapest ticket price $30 (€24) |
Trains per day 12 |
Fastest train 4h 8m |
First train 11:43 AM |
Last train 3:56 PM |
Cheapest Month Nov |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Sun |
Least Busy Day Wed |
Train companies: Frecciarossa, Italo, Regionale, Intercity, Trenitalia, Trenord from Domodossola station to Florence Santa Maria Novella trainsFrecciarossa, Italo, Regionale, Intercity, Trenitalia, Trenord trains will get you between Domodossola station and Florence Santa Maria Novella from $30 (€24). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Regionale
Intercity
Trenitalia
Trenord
FAQs: Trains from Domodossola station to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Domodossola station to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Domodossola station to Florence Santa Maria Novella
Most Domodossola station to Florence Santa Maria Novella trains use the Domodossola to Firenze Santa Maria Novella station pair. Use this guide to compare Domodossola station and Florence Santa Maria Novella train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Getting to Domodossola from Domodossola city centre
Domodossola train station facilities and services
Domodossola has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Ristorante La Meridiana, Osteria Vecchio Borgo
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Domodossola. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Domodossola. Lost and found is available at the station.
Parking, taxis and toilets
Available at Domodossola: Parking, Taxis, WC.
Bike and car services
Available at Domodossola: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Domodossola: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotel Corona, Hotel Ristorante Eurossola, Hotel Domodossola.
Getting to Firenze Santa Maria Novella from Florence city centre
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
Firenze Santa Maria Novella train station facilities and services
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Wi-Fi and ATMs
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
Tickets and information
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Parking, taxis and toilets
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Bike and car services
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
Most popular train connections from Domodossola station
More options for your journey from Domodossola station to Florence Santa Maria Novella
Here are some other resources that might have the information you need
