The cheapest and fastest trains from Domodossola to Rome
Cheapest price
$87
Average price
$142
Fastest journey
5 h 18 m
Average duration
5 h 21 m
Trains per day
71
Distance
577 km
The best way to find a cheap train ticket from Domodossola to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Domodossola to Rome will cost around $142 if you buy it on the day, but the cheapest tickets can be found for only $87.
It's difficult to get from Domodossola to Rome without transferring at least once.
Regionale 11439+
InterCityNotte 797
Regionale TRENORD 2413+
Intercity 657+
ETRUSCHI LINE 4133
Regionale TRENORD 2411 · Regionale Veloce TTPER 2455+
Intercity 584
Regionale 10203 · Regionale TRENORD 10342+
Intercity 597
Autobus EC061+
Intercity 597
Regionale TRENORD 2435+
FRECCIAROSSA 9661
Regionale TRENORD 2411+
FRECCIAROSSA 9607
Regionale TRENORD 2413+
FRECCIAROSSA 1000 9611
Regionale TRENORD 2407+
FRECCIAROSSA 1000 9641
Regionale TRENORD 2431+
FRECCIAROSSA 1000 9649Travel Information
Compare train and flight for Domodossola to Rome
Omio recommends booking the train as it is the most popular option from Domodossola to Rome among Omio's users. If you are prioritising price take the train with prices starting from $39. For those with little time consider booking a flight which can get you there in 1h 13m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a train costs an average of $39, and a flight costs an average of $53.
Distance: 358 miles (577 km)
Compare train with
Most popular Train | Flight |
|---|---|
$64 Average price Cheapest | $88 Average price |
7h 9m Average total duration 6h 39m Onboard + 30m Additional time* | 4h 13m Average total duration Fastest 1h 13m Onboard + 3h 0m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Domodossola to Rome train times
The table below shows live departures for Domodossola to Rome trains for today, Saturday, March 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:56 PM Domodossola | 5h14 | 9:10 PM Rome | 0 transfersDirect | |
![]() | 5:07 PM Domodossola | 13h25 | 6:32 AM Rome | 0 transfersDirect | |
![]() | 5:48 PM Domodossola | 11h05 | 4:53 AM Rome | 0 transfersDirect | |
![]() | 5:56 PM Domodossola | 11h10 | 5:06 AM Rome | 0 transfersDirect | |
| Sunday, March 22 | |||||
Regionale TRENORD 2411+ 9971 | On time 3:52 AM Domodossola station | 5h33 | 9:25 AM Rome Termini | 1 transfer | |
Regionale TRENORD 2411+ FRECCIAROSSA 9607 | 3:52 AM Domodossola station | 5h19 | 9:11 AM Rome Termini | 1 transfer | |
Regionale TRENORD 2411 · Regionale Veloce TTPER 2455+ Intercity 584 | 3:52 AM Domodossola station | 11h28 | 3:20 PM Rome Termini | 2 transfers | |
Regionale TRENORD 2411+ 9917 | On time 3:52 AM Domodossola station | 6h27 | 10:19 AM Rome Termini | 1 transfer | |
Regionale TRENORD 2411+ 9941 | On time 3:52 AM Domodossola station | 6h08 | 10:00 AM Rome Termini | 1 transfer | |
Regionale TRENORD 2413+ FRECCIAROSSA 1000 9611 | 4:50 AM Domodossola station | 5h20 | 10:10 AM Rome Termini | 1 transfer | |
Regionale TRENORD 2413+ Intercity 657+ ETRUSCHI LINE 4133 | 4:50 AM Domodossola station | 12h00 | 4:50 PM Rome Termini | 2 transfers | |
Regionale TRENORD 2413+ 9998 | 4:50 AM Domodossola station | 5h35 | 10:25 AM Rome Termini | 1 transfer | |
Regionale TRENORD 2413+ 9927 | 4:50 AM Domodossola station | 9h15 | 2:05 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2413+ 9919 | On time 4:50 AM Domodossola station | 6h29 | 11:19 AM Rome Termini | 1 transfer | |
Regionale TRENORD 2415+ 9927 | 5:50 AM Domodossola station | 8h15 | 2:05 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2415+ 9985 | 5:50 AM Domodossola station | 10h40 | 4:30 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2415+ FRECCIAROSSA 9583 | 5:50 AM Domodossola station | 6h44 | 12:34 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2415+ 9983 | 5:50 AM Domodossola station | 9h40 | 3:30 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2417+ 9985 | 6:52 AM Domodossola station | 9h38 | 4:30 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2417+ FRECCIAROSSA 9527 | 6:52 AM Domodossola station | 6h42 | 1:34 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2417+ 9927 | 6:52 AM Domodossola station | 7h13 | 2:05 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2417+ Intercity 1549 · Intercity 511 | 6:52 AM Domodossola station | 10h11 | 5:03 PM Rome Termini | 2 transfers | |
Regionale TRENORD 2417+ 9983 | 6:52 AM Domodossola station | 8h38 | 3:30 PM Rome Termini | 1 transfer | |
Regionale 10209+ 9959 | 7:07 AM Domodossola station | 14h13 | 9:20 PM Rome Termini | 1 transfer | |
Regionale 10209+ 9939 | On time 7:07 AM Domodossola station | 9h12 | 4:19 PM Rome Termini | 1 transfer | |
Regionale 10209+ 6143 | 7:07 AM Domodossola station | 10h12 | 5:19 PM Rome Termini | 1 transfer | |
Autobus EC041+ 9985 | 7:30 AM Domodossola station | 9h00 | 4:30 PM Rome Termini | 1 transfer | |
Autobus EC041+ 9931 | On time 7:30 AM Domodossola station | 6h49 | 2:19 PM Rome Termini | 1 transfer | |
Autobus EC041+ 9983 | 7:30 AM Domodossola station | 8h00 | 3:30 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2419+ 9931 | On time 7:52 AM Domodossola station | 6h27 | 2:19 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2419+ 9985 | 7:52 AM Domodossola station | 8h38 | 4:30 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2419+ FRECCIAROSSA 1000 9623 | 7:52 AM Domodossola station | 5h59 | 1:51 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2419+ 9983 | 7:52 AM Domodossola station | 7h38 | 3:30 PM Rome Termini | 1 transfer | |
Autobus EC061+ 9983 | 8:30 AM Domodossola station | 7h00 | 3:30 PM Rome Termini | 1 transfer | |
Autobus EC061+ 9987 | 8:30 AM Domodossola station | 8h55 | 5:25 PM Rome Termini | 1 transfer | |
Autobus EC061+ FRECCIAROSSA 9535 | 8:30 AM Domodossola station | 6h19 | 2:49 PM Rome Termini | 1 transfer | |
Autobus EC061+ 9985 | 8:30 AM Domodossola station | 8h00 | 4:30 PM Rome Termini | 1 transfer | |
Autobus EC061+ Intercity 597 | 8:30 AM Domodossola station | 11h50 | 8:20 PM Rome Ostiense | 1 transfer | |
Regionale 10203 · Regionale TRENORD 10342+ Intercity 597 | 9:05 AM Domodossola station | 11h15 | 8:20 PM Rome Ostiense | 2 transfers | |
Regionale 10203+ 9963 | 9:05 AM Domodossola station | 14h19 | 11:24 PM Rome Termini | 1 transfer | |
Regionale 10203+ 9939 | On time 9:05 AM Domodossola station | 7h14 | 4:19 PM Rome Termini | 1 transfer | |
Regionale 10203+ 6143 | 9:05 AM Domodossola station | 8h14 | 5:19 PM Rome Termini | 1 transfer | |
Regionale 10203 · S1 TRENORD 24041+ FRECCIAROSSA 1000 9539 | 9:05 AM Domodossola station | 6h44 | 3:49 PM Rome Termini | 2 transfers | |
Regionale 10207+ 9963 | 11:07 AM Domodossola station | 12h17 | 11:24 PM Rome Termini | 1 transfer | |
Regionale 10207+ 9959 | 11:07 AM Domodossola station | 10h13 | 9:20 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2407+ 9989 | 11:52 AM Domodossola station | 6h33 | 6:25 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2407+ 9987 | 11:52 AM Domodossola station | 5h33 | 5:25 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2407+ 9991 | 11:52 AM Domodossola station | 7h34 | 7:26 PM Rome Termini | 1 transfer | |
Regionale TRENORD 2407+ Intercity 641+ InterCityNotte 795 | 11:52 AM Domodossola station | 10h31 | 10:23 PM Rome Ostiense | 2 transfers | |
Regionale TRENORD 2407+ FRECCIAROSSA 1000 9641 | 11:52 AM Domodossola station | 5h23 | 5:15 PM Rome Termini | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Domodossola to Rome by train or flight
Compare train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Domodossola to Rome trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Intercity Notte, Intercity or Regionale to find the best option for your trip from Domodossola to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train and flight to ensure you get the best deal for traveling from Domodossola to Rome.
Journey information
Overview: Train from Domodossola to Rome
Trains from Domodossola to Rome run on average 15 times per day, taking around 6h 39m. Cheap train tickets for this journey start at $39 (€31) if you book in advance.
The earliest train runs at 00:01, the last at 23:55. The fastest train covers the 358 miles (577 km) distance in 5h 14m.
Distance 358 miles (577 km) |
Average train duration 6h 39m |
Cheapest ticket price $39 (€31) |
Trains per day 15 |
Fastest train 5h 14m |
First train 00:01 |
Last train 23:55 |
Cheapest month Oct |
Cheapest day Tue |
High season Oct - Dec |
Low season Jan - Mar |
Busiest day Thu |
Least busy day Sat |
Best day to book ahead 5 days |
Train companies: Italo, Frecciarossa, Intercity Notte, Intercity, Regionale from Domodossola to Rome trainsItalo, Frecciarossa, Intercity Notte, Intercity, Regionale trains will get you between Domodossola and Rome from $39 (€31). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity Notte
Intercity
Regionale
FAQs: Trains from Domodossola to Rome
Find answers to the most common questions about traveling from Domodossola to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Domodossola to Rome
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, accessible from the main entrance.
- Ristorante La Meridiana
- Osteria Vecchio Borgo
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Corona
- Hotel Ristorante Eurossola
- Hotel Domodossola
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for trains to Switzerland and regional destinations
- Train: Regional and Eurocity trains
- Bus: Several local lines available
- Mon - Sun: 06:30 - 22:00
- Free WiFi in the station.
- Provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
- Acafe
- Moka Café
- Roadhouse Grill
- McDonald's
- Gusto
- Chef Express
- Coop Minimarket
- Mercato Centrale
- The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
- Archi di Roma Guest House
- Gemma di Roma
- The Liberty Boutique Hotel
- Mon - Sun: 06:30 - 22:00
- Located near Platform 24.
- Metro lines: A (red), B (blue)
- Bus lines: 5, H, 38, 40 Express, 50 Express, 64, 66, 70, 75, 82, 90 Express, 92, 105, 150F, 223, 310, 590, 714, 910, C2, C3
- Tram lines: 5, 14
- Train lines: Italo, FR, FA, FB, IC, ICN, EN, CNL, R, Leonardo Express
- Mon - Sun: 06:35 - 20:20
- Free, limited Wi-Fi available in the station for 15 minutes.
- Luggage lockers are located in the station lobby.
- Rock n’ Coffee Roma
- Arabian Kebab
- Ingredienti
- McDonald’s
- Numb's Bakery Café
- Accessible facilities include elevators and escalators.
- B&B Rome Tiburtina
- B&B Alba Domus Roma
- Hotel delle Province
- Mon - Sun: 06:35 - 20:20
- Located inside the main terminal.
- Metro lines: LB
- Bus lines: 62, 71, 111, 111F, 120F, 135, 163, 168, 211, 309, 409, n409, n041, C2, C3, Airport Shuttle
- Train lines: FR, FA, IC, REG, FL1, FL2, FL3
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options.
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
Most popular train connections from Domodossola
More options for your journey from Domodossola to Rome
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