The cheapest and fastest trains from Domodossola to Florence Santa Maria Novella
Cheapest price on Sep 20
$42
Average ticket price on Sep 20
$42
Fastest journey on Sep 20
7 h 14 m
Average journey duration on Sep 20
7 h 16 m
Trains on Sep 20
2
Distance
349 km
The best way to find a cheap train ticket from Domodossola to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Domodossola to Florence Santa Maria Novella will cost around $42 if you buy it on the day, but the cheapest tickets can be found for only $42.
On Sun, Sep 20, we found 2 trains from Domodossola to Florence Santa Maria Novella, including 2 direct services.
On Sun, Sep 20 the direct trains cover the 349 km distance in an average of 7 h 16 m but if you time it right, some trains will get you there in just 7 h 14 m .
On Sun, Sep 20 the slowest trains will take 7 h 18 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:56 PM7h14Domodossola8:10 PMFlorence Santa Maria Novella$421One-way0 transfers
1:52 PM7h18Domodossola9:10 PMFlorence Santa Maria Novella$421One-way0 transfers
12:56 PM7h14Domodossola8:10 PMFlorence Santa Maria Novella$421One-way0 transfers
1:52 PM7h18Domodossola9:10 PMFlorence Santa Maria Novella$421One-way0 transfers
Travel Information
Compare train, bus, and flight for Domodossola to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Domodossola to Florence Santa Maria Novella among Omio's users. If you are prioritising price, take the train, with an average ticket price of $73 For those with little time, consider booking a flight, which has an average total journey time of 5h 2m. Average ticket prices depend on the travel mode: a train costs an average of $73, while a flight costs an average of $471.
Distance: 216 miles (349 km)
Compare train with
Most popular Train | Flight | Driving |
|---|---|---|
$73 Average price Cheapest | $471 Average price | $128 Average price (fuel + tolls) |
5h 21m Average total duration 4h 51m Onboard + 30m Additional time* | 5h 2m Average total duration Fastest 3h 2m Onboard + 2h 0m Additional time* | 4h 42m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Domodossola to Florence Santa Maria Novella:
A train is $398 less than a flight for this route with tickets for a flight from Domodossola to Florence Santa Maria Novella costing on average $471.
Other travel options to Florence Santa Maria Novella take longer:
Train takes on average 4h 51m.
Tickets start at around $73 compared to roughly $128 in fuel and tolls — a saving of about $55. The journey takes 4h 51m versus 4h 42m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare prices and tickets Domodossola to Florence Santa Maria Novella by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 20
Sep 21
Sep 22
Sep 23
Sep 24
Sep 25
Sep 26
Why should you book Domodossola to Florence Santa Maria Novella trains with Omio?
Why book with Omio vs Intercity?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity, but also compare tickets for the likes of Frecciarossa or Regionale to find the best option for your trip from Domodossola to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Domodossola to Florence Santa Maria Novella.
Journey information
Overview: Train from Domodossola to Florence Santa Maria Novella
Trains from Domodossola to Florence Santa Maria Novella run on average 10 times per day, taking around 4h 51m. Cheap train tickets for this journey start at $37 if you book in advance.
The earliest train runs at 10:07, the last at 15:55. The fastest train covers the 216 miles (349 km) distance in 3h 33m.
Distance 216 miles (349 km) |
Average train duration 4h 51m |
Cheapest ticket price $37 |
Trains per day 10 |
Fastest train 3h 33m |
First train 10:07 AM |
Last train 3:55 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sat |
Train companies: Frecciarossa, Regionale, Intercity from Domodossola to Florence Santa Maria Novella trainsFrecciarossa, Regionale, Intercity trains will get you between Domodossola and Florence Santa Maria Novella from $37. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Regionale
Intercity
FAQs: Trains from Domodossola to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Domodossola to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Domodossola to Florence Santa Maria Novella
Most Domodossola to Florence Santa Maria Novella trains use the Domodossola to Firenze Santa Maria Novella station pair. Use this guide to compare Domodossola and Florence Santa Maria Novella train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Getting to Domodossola from Domodossola city centre
Domodossola train station facilities and services
Domodossola has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Ristorante La Meridiana, Osteria Vecchio Borgo
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Domodossola. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Domodossola. Lost and found is available at the station.
Parking, taxis and toilets
Available at Domodossola: Parking, Taxis, WC.
Bike and car services
Available at Domodossola: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Domodossola: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotel Corona, Hotel Ristorante Eurossola, Hotel Domodossola.
Getting to Firenze Santa Maria Novella from Florence city centre
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
Firenze Santa Maria Novella train station facilities and services
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Wi-Fi and ATMs
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
Tickets and information
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Parking, taxis and toilets
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Bike and car services
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
Most popular train connections from Domodossola
More options for your journey from Domodossola to Florence Santa Maria Novella
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