- Must visit
Galleria degli Uffizi
Florence’s flagship art museum, famous for Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Cheapest price
$58
Average price
$83
Fastest journey
4 h 54 m
Average duration
5 h
Trains per day
10
Distance
349 km
The best way to find a cheap train ticket from Domodossola to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Domodossola to Florence Santa Maria Novella will cost around $83 if you buy it on the day, but the cheapest tickets can be found for only $58.
It's difficult to get from Domodossola to Florence Santa Maria Novella without transferring at least 2 times.
Autobus TRENORD 4431A · Regionale TRENORD 2431+
Intercity 599
Autobus EC061+
Intercity 597+
Regionale 18232
Autobus TRENORD 4431A · Regionale TRENORD 2431+
FRECCIAROSSA 9555
Autobus TRENORD 2427A · Regionale TRENORD 2427+
FRECCIAROSSA 9547
Autobus TRENORD 4417A · Regionale TRENORD 2417+
FRECCIAROSSA 9527
Autobus TRENORD 2427A · Regionale TRENORD 2427+
FRECCIAROSSA 9547
Autobus TRENORD 4431A · Regionale TRENORD 2431+
FRECCIAROSSA 9555
Autobus TRENORD 4417A · Regionale TRENORD 2417+
FRECCIAROSSA 9527
Autobus TRENORD 4437A · Regionale TRENORD 2437+
FRECCIAROSSA 9567
Autobus TRENORD 4411A · Regionale TRENORD 2411+
FRECCIAROSSA 9515Omio recommends booking the train as it is the most popular option from Domodossola to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the train with prices starting from $41. For those with little time consider booking a train which can get you there in 4h 40m. The ticket price range depends on the travel mode: a train costs an average of $41, and a bus costs an average of $90.
Distance: 216 miles (349 km)
Most popular Train | Bus | Driving |
|---|---|---|
$44 Average price Cheapest | $104 Average price | $127 Average price (fuel + tolls) |
5h 10m Average total duration Fastest 4h 40m Onboard + 30m Additional time* | 5h 56m Average total duration 5h 26m Onboard + 30m Additional time* | 4h 42m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Domodossola to Florence Santa Maria Novella:
A train is $60 (€49) less than a bus for this route with tickets for a bus from Domodossola to Florence Santa Maria Novella costing on average $104 (€85).
Other travel options to Florence Santa Maria Novella take longer:
Bus takes on average 5h 26m.
The journey is about 2m faster (4h 40m by train vs 4h 42m by car) and roughly $83 (€68) cheaper once you factor in fuel and tolls ($44 (€36) vs $127 (€104)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Domodossola to Florence Santa Maria Novella trains for today, Sunday, June 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 11417 · Regionale Veloce 3097 · Regionale 18395 | 6:48 AM Domodossola station | 9h20 | 4:08 PM Florence Santa Maria Novella | 2 transfers | |
Autobus EC061+ Intercity 89469+ Regionale 18525 | 9:30 AM Domodossola station | 8h22 | 5:52 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4207A · Regionale 10207+ FRECCIAROSSA 9321 | 11:21 AM Domodossola station | 5h29 | 4:50 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4407A · Regionale TRENORD 2407+ FRECCIAROSSA 9547 | 12:03 PM Domodossola station | 5h01 | 5:04 PM Florence Santa Maria Novella | 2 transfers | |
Regionale 11427 · Regionale Veloce 2029+ FRECCIAROSSA 9551 | 12:45 PM Domodossola station | 5h19 | 6:04 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4201A · Regionale 10201+ FRECCIAROSSA 9325 | 1:21 PM Domodossola station | 5h29 | 6:50 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ Intercity 599 | 2:03 PM Domodossola station | 7h19 | 9:22 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ FRECCIAROSSA 9555 | 2:03 PM Domodossola station | 5h01 | 7:04 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4437A · Regionale TRENORD 2437+ FRECCIAROSSA 9567 | 5:03 PM Domodossola station | 5h01 | 10:04 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4439A · Regionale TRENORD 2439+ FRECCIAROSSA 9573 | 6:03 PM Domodossola station | 5h11 | 11:14 PM Florence Santa Maria Novella | 2 transfers | |
Autobus TRENORD 4411A · Regionale TRENORD 2411+ FRECCIAROSSA 9515 | 4:03 AM Domodossola station | 5h01 | 9:04 AM Florence Santa Maria Novella | 2 transfers | |
Regionale 11413 · Regionale Veloce 2053+ FRECCIAROSSA 9391 | 5:20 AM Domodossola station | 5h30 | 10:50 AM Florence Santa Maria Novella | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Domodossola to Florence Santa Maria Novella run on average 13 times per day, taking around 4h 40m. Cheap train tickets for this journey start at $41 (€34) if you book in advance.
The earliest train runs at 10:07, the last at 16:56. The fastest train covers the 216 miles (349 km) distance in 4h 8m.
Distance 216 miles (349 km) |
Average train duration 4h 40m |
Cheapest ticket price $41 (€34) |
Trains per day 13 |
Fastest train 4h 8m |
First train 10:07 AM |
Last train 4:56 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Mon |
Discover the best of Firenze Santa Maria Novella — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Firenze Santa Maria Novella trip today.
Florence’s flagship art museum, famous for Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Best known for Michelangelo’s David, plus important Florentine paintings and sculpture. Advance booking is commonly needed.
Vast former Medici palace housing several museum collections, including Palatine Gallery interiors and royal apartments.
The symbolic heart of Florence, packed with the cathedral complex and some of the city’s most photographed architecture.
Historic civic square filled with monumental sculpture and framed by Palazzo Vecchio and the Loggia dei Lanzi.
The classic panoramic terrace over Florence, especially popular at sunset and widely featured in travel photography and social media.
The iconic Florentine T-bone steak, cut very thick from Chianina beef and grilled rare over coals. It is one of the city’s most famous traditional dishes.
A classic Florentine street food made from the fourth stomach of the cow, simmered in broth and usually served in a bread roll with green sauce or spicy oil.
A hearty Tuscan soup of bread, cannellini beans, and vegetables, especially black cabbage. It is a rustic peasant dish strongly associated with Florence and Tuscany.
Established Michelin-starred restaurant offering refined contemporary Tuscan cuisine in an elegant setting within central Florence.
Long-established local favorite known for its intimate old-school atmosphere and classic dishes such as butter chicken and Tuscan comfort food.
Historic, no-frills Florentine trattoria near the central market, famous for traditional Tuscan dishes including steak, ribollita, and hearty daily specials.
Moderate for Italy: cafés and casual meals are reasonable, but hotels and tourist-area dining near the station cost more.
Service is often included or covered by coperto. Tipping is not obligatory; round up or leave EUR 1-2 at cafés, 5-10% for great restaurant service, and round up taxis.
Official public transport app
Firenze Santa Maria Novella -> Piazza del Duomo, Florence
Find answers to the most common questions about traveling from Domodossola to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

Most Domodossola to Florence Santa Maria Novella trains use the Domodossola to Firenze Santa Maria Novella station pair, with some services arriving at Firenze Rifredi. Use this guide to compare Domodossola and Florence Santa Maria Novella train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Domodossola has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Ristorante La Meridiana, Osteria Vecchio Borgo
Free. ATMs are available in the train station.
Ticket office support is available at Domodossola. Information desks are located in the main hall.
Luggage storage is available at Domodossola. Lost and found is available at the station.
Available at Domodossola: Parking, Taxis, WC.
Available at Domodossola: Bike Parking, Car Rental.
Accessibility facilities are available at Domodossola: Elevators, ramps.
Nearby hotels include Hotel Corona, Hotel Ristorante Eurossola, Hotel Domodossola.
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
Firenze Rifredi is 3 km from Florence city centre. Public transport options include:
Firenze Rifredi has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Information Desk, and Luggage Carts.
Food options include: Trattoria Fratelli Briganti, Osteria di Poneta
Free.
Ticket office support is available at Firenze Rifredi. Information desks are located in the main hall.
Luggage storage is available at Firenze Rifredi. Lost and found is available at the station.
Available at Firenze Rifredi: Parking, Taxis, WC.
Available at Firenze Rifredi: Bike Parking, Bike Rental.
Accessibility facilities are available at Firenze Rifredi: Elevators, ramps, restrooms.
Nearby hotels include Hotel Raffaello, Hotel Corolle, Hotel Dalmazia.
Firenze Campo di Marte is 2 km from Florence city centre. Public transport options include:
Firenze Campo di Marte has practical services for this route, including Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, and Bike Rental.
Food options include: Moka Café
The ticket office is open Mon - Sun: 07:15 - 20:45.
Available at Firenze Campo di Marte: Taxis, WC.
Available at Firenze Campo di Marte: Bike Parking, Bike Rental.
Accessibility facilities are available at Firenze Campo di Marte: The station is fully accessible, with step-free access throughout the station.
Nearby hotels include Florence Stadium B&B, Hotel Villa Liana, Hotel della Robbia.
Here are some other resources that might have the information you need