The cheapest and fastest trains from Domodossola to Florence Santa Maria Novella
Cheapest price
$40
Average price
$46
Fastest journey
6 h 28 m
Average duration
8 h 9 m
Trains per day
3
Distance
349 km
The best way to find a cheap train ticket from Domodossola to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Domodossola to Florence Santa Maria Novella will cost around $46 if you buy it on the day, but the cheapest tickets can be found for only $40.
Of the 3 trains that leave Domodossola for Florence Santa Maria Novella on Sat, Nov 08, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Nov 08 the direct trains cover the 349 km distance in an average of 8 h 9 m but if you time it right, some trains will get you there in just 6 h 28 m .
On Sat, Nov 08 the slowest trains will take 9 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare bus, train, and flight for Domodossola to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Domodossola to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the train with prices starting from €26. For those with little time consider booking a bus which can get you there in 4h 34m. The ticket price range depends on the travel mode: a train costs an average of €26, and a flight costs an average of €142.
Distance: 216 miles (349 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€36 Average price Cheapest | €77 Average price | €170 Average price |
5h 9m Average total duration 4h 39m Onboard + 30m Additional time* | 5h 4m Average total duration Fastest 4h 34m Onboard + 30m Additional time* | 10h 55m Average total duration 7h 55m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Domodossola to Florence Santa Maria Novella train times
The table below shows live departures for Domodossola to Florence Santa Maria Novella trains for today, Friday, November 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:30 AM Domodossola | 8h40 | 8:10 PM Florence Santa Maria Novella | 0 transfersDirect | |
![]() | 11:59 AM Domodossola | 7h23 | 7:22 PM Florence Santa Maria Novella | 0 transfersDirect | |
![]() | 12:56 PM Domodossola | 7h14 | 8:10 PM Florence Santa Maria Novella | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Domodossola to Florence Santa Maria Novella by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Nov 14
Journey information
Overview: Train from Domodossola to Florence Santa Maria Novella
Trains from Domodossola to Florence Santa Maria Novella run on average 13 times per day, taking around 4h 39m. Cheap train tickets for this journey start at $31 (€26) if you book in advance.
The earliest train runs at 02:56, the last at 12:56. The fastest train covers the 216 miles (349 km) distance in 4h 43m.
Distance 216 miles (349 km) |
Average train duration 4h 39m |
Cheapest ticket price $31 (€26) |
Trains per day 13 |
Fastest train 4h 43m |
First train 02:56 |
Last train 12:56 |
Train companies: Frecciarossa, Italo, Regionale, Intercity, Trenitalia from Domodossola to Florence Santa Maria Novella trainsFrecciarossa, Italo, Regionale, Intercity, Trenitalia trains will get you between Domodossola and Florence Santa Maria Novella from $31 (€26). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Regionale
Intercity
Trenitalia
FAQs: Trains from Domodossola to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Domodossola to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Domodossola to Florence Santa Maria Novella
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, accessible from the main entrance.
- Ristorante La Meridiana
- Osteria Vecchio Borgo
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Corona
- Hotel Ristorante Eurossola
- Hotel Domodossola
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for trains to Switzerland and regional destinations
- Train: Regional and Eurocity trains
- Bus: Several local lines available
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
Most popular train connections from Domodossola
More options for your journey from Domodossola to Florence Santa Maria Novella
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