- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
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The cheapest and fastest buses from Winston Salem, NC to St. Louis, MO
Showing times and prices for Jun 21
Cheapest price
$169
Average price
$183
Fastest journey
20 h 10 m
Average duration
21 h 28 m
Buses per day
2
Distance
923 km
Cheap tickets
The best way to find a cheap bus ticket from Winston Salem, NC to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Winston Salem, NC to St. Louis, MO will cost around $183 if you buy it on the day, but the cheapest tickets can be found for only $169.
Fast buses
It's difficult to get from Winston Salem, NC to St. Louis, MO without transferring at least once.
10:25 AM22h45Winston Salem, NC9:10 AMSt. Louis, MO$1691One-way2 transfers
7:10 PM20h10Winston Salem, NC3:20 PMSt. Louis, MO$1981One-way1 transfer
- 7:10 PM20h10Winston Salem, NC3:20 PMSt. Louis, MO$1981One-way1 transfer
- 10:25 AM22h45Winston Salem, NC9:10 AMSt. Louis, MO$1691One-way2 transfers
Winston Salem, NC to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 10:25AM | Arrival Time 09:10AM | Duration 22h45 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $169 |
Operator Barons Bus | Departure Time 07:10PM | Arrival Time 03:20PM | Duration 20h10 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $198 |
Live departures
Winston Salem, NC to St. Louis, MO bus times
The table below shows live departures for Winston Salem, NC to St. Louis, MO buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 7:10 PM Winston Salem, NC | 20h10 | 3:20 PM St. Louis, MO | 1 transfer | |
| Sunday, June 21 | |||||
| 10:25 AM Winston Salem, NC | 22h45 | 9:10 AM St. Louis, MO | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Winston Salem, NC to St. Louis, MO by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Winston Salem, NC to St. Louis, MO buses with Omio?
Barons Bus as well as Greyhound offer buses services from Winston Salem, NC to St. Louis, MO.
Omio is the only official third party seller for Barons Bus tickets.
Why book with Omio vs Barons Bus?
- Compare with other providers: On Omio, you can not only buy tickets for Barons Bus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Winston Salem, NC to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Winston Salem, NC to St. Louis, MO
USAUSA
Buses from Winston Salem, NC to St. Louis, MO run on average 2 times per day, taking around 21h 20m. Cheap bus tickets for this journey start at $169 (€138) if you book in advance.
The earliest bus runs at 01:40, the last at 23:30. The fastest bus covers the 573 miles (923 km) distance in 20h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 573 miles (923 km) |
Average bus duration 21h 20m |
Cheapest ticket price $169 (€138) |
Buses per day 2 |
Fastest bus 20h 10m |
First bus 1:40 AM |
Last bus 11:30 PM |
High Season Jan - Mar |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Barons Bus, Greyhound from Winston Salem, NC to St. Louis, MOYou can travel by bus between Winston Salem, NC to St. Louis, MO with Barons Bus, Greyhound for as low as $169 (€138). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
22h 45m
Cheapest Price
$169 (€138)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Barons Bus
Luggage & cancellation policy
Average Duration
20h 10m
Cheapest Price
$198 (€162)
Barons Bus frequency
1 a day
Complete guide to St. Louis
Things to do in St. Louis
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
- Must visit
City Museum
Highly original museum and artist-built environment with architectural salvage, tunnels, slides, and installations. One of the city’s most distinctive and widely shared attractions.
- Recommended
Missouri History Museum
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions. Well suited for visitors wanting local context.
- Must visit
Forest Park
One of the largest urban parks in the United States, home to major institutions, lakes, trails, and broad green spaces. Essential for first-time visitors.
- Must visit
Gateway Arch National Park Grounds
Riverfront grounds around the Arch with lawns, paths, and strong skyline views, useful for walking and iconic photos.
- Recommended
The Delmar Loop
Lively entertainment and walking district known for music venues, public art, shops, and the St. Louis Walk of Fame.
- Vegetarian
St. Louis-Style Pizza
A local pizza style with a very thin, cracker-like crust, cut into squares and traditionally topped with Provel cheese. It is one of the city’s signature foods.
Toasted Ravioli
Breaded and fried meat- or cheese-filled ravioli, usually served with marinara sauce. This St. Louis Italian-American specialty is strongly associated with The Hill neighborhood.
- Vegetarian
Gooey Butter Cake
A rich, dense cake with a buttery base and sweet cream cheese-like topping. It is one of the most famous desserts identified with St. Louis.
Charlie Gitto's On The Hill
A long-established Italian restaurant on The Hill, known for classic red-sauce dishes, toasted ravioli, and an old-school fine dining feel.
Ted Drewes Frozen Custard
An iconic St. Louis custard stand famous for thick concretes and nostalgic roadside charm. A must for trying the city’s best-known frozen treat.
Sidney Street Cafe
A respected contemporary American restaurant known for refined cooking, strong wine service, and a polished neighborhood setting.
United States Dollar
Generally moderate by U.S. standards. Hotels and attractions are often reasonable, while dining costs vary by neighborhood and venue.
Average meal costs
- Budget
- USD 10-18 for fast food or casual spots.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 70+ per person before drinks and tip.
- Coffee
- USD 3-6 for regular coffee or a latte.
Tipping culture
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
FAQs: Bus from Winston Salem, NC to St. Louis, MO
Find answers to the most common questions about traveling from Winston Salem, NC to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Winston Salem, NC to St. Louis, MO can start from as little as $169 (€138) when you book in advance. The average bus ticket price for Winston Salem, NC to St. Louis, MO is $189 (€155) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Winston Salem, NC to St. Louis, MO is 20h 10m to travel the 573 miles (923 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Winston Salem, NC to St. Louis, MO leaves at 1:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Winston Salem, NC to St. Louis, MO leaves at 11:30 PM.
There are 2 buses a day from Winston Salem, NC to St. Louis, MO which require at least one change with Barons Bus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Winston Salem, NC to St. Louis, MO, you can count on Barons Bus, Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Winston Salem, NC and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
A trip to St. Louis, MO from Winston Salem, NC is worth doing but not as a day trip with a journey time of 20h 10m each way. Check with Omio app the best way to travel.
Yes, you can take a bus between Winston Salem, NC and St. Louis, MO.
Yes, there are bathrooms on board the bus from Winston Salem, NC to St. Louis, MO for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Winston Salem, NC to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Winston Salem, NC to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Winston Salem, NC to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Winston Salem, NC to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Winston Salem, NC to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Winston Salem, NC to St. Louis, MO.
You can reserve your seat on the bus from Winston Salem, NC to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Winston Salem, NC to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Winston Salem, NC to St. Louis, MO with the following bus company: Greyhound.
Since neither Winston Salem, NC nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Winston Salem, NC to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Winston Salem, NC to St. Louis, MO
Winston Salem
St. Louis
The major bus station for departures in Winston Salem is Winston Salem, W 5th St (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Winston Salem, W 5th St (Greyhound Bus Station) for your trip from Winston Salem to St. Louis.
Winston Salem, W 5th St (Greyhound Bus Station)
information
The major bus station for arrivals in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip to St. Louis from Winston Salem.
St. Louis, S 15th St (Civic center)
information
Most popular bus connections from Winston Salem, NC
More options for your journey from Winston Salem, NC to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Winston Salem, NC
Most popular bus connections to St. Louis, MO
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