- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
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The cheapest and fastest buses from Winston Salem, NC to St. Louis, MO
Showing times, prices and bookable tickets for Sep 19
Cheapest price on Sep 19
$169
Average ticket price on Sep 19
$183
Fastest journey on Sep 19
20 h 10 m
Average journey duration on Sep 19
21 h 28 m
Buses on Sep 19
2
Distance
923 km
Cheap tickets
The best way to find a cheap bus ticket from Winston Salem, NC to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Winston Salem, NC to St. Louis, MO will cost around $183 if you buy it on the day, but the cheapest tickets can be found for only $169.
Fast buses
It's difficult to get from Winston Salem, NC to St. Louis, MO without transferring at least once.
10:25 AM22h45Winston Salem, NC9:10 AMSt. Louis, MO$1691One-way2 transfers
7:10 PM20h10Winston Salem, NC3:20 PMSt. Louis, MO$1981One-way1 transfer
- 7:10 PM20h10Winston Salem, NC3:20 PMSt. Louis, MO$1981One-way1 transfer
- 10:25 AM22h45Winston Salem, NC9:10 AMSt. Louis, MO$1691One-way2 transfers
Winston Salem, NC to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 10:25AM | Arrival Time 09:10AM | Duration 22h45 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $169 |
Operator Barons Bus | Departure Time 07:10PM | Arrival Time 03:20PM | Duration 20h10 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $198 |
Live departures
Winston Salem, NC to St. Louis, MO bus times
The table below shows live departures for Winston Salem, NC to St. Louis, MO buses for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 10:25 AM Winston Salem, NC | 22h45 | 9:10 AM St. Louis, MO | 2 transfers | |
| 7:10 PM Winston Salem, NC | 20h10 | 3:20 PM St. Louis, MO | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Winston Salem, NC to St. Louis, MO by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Winston Salem, NC to St. Louis, MO buses with Omio?
Barons Bus as well as Greyhound offer buses services from Winston Salem, NC to St. Louis, MO.
Omio is the only official third party seller for Barons Bus tickets.
Why book with Omio vs Barons Bus?
- Compare with other providers: On Omio, you can not only buy tickets for Barons Bus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Winston Salem, NC to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Barons Bus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Winston Salem, NC to St. Louis, MO.
Bus providers: Barons Bus, Greyhound from Winston Salem, NC to St. Louis, MOYou can travel by bus between Winston Salem, NC to St. Louis, MO with Barons Bus, Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
22h 45m
Cheapest Greyhound Price
$169
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Barons Bus
Luggage & cancellation policy
Average Barons Bus Duration
20h 10m
Cheapest Barons Bus Price
$198
Barons Bus frequency
1 a day
Complete guide to St. Louis, MO
Things to do in St. Louis, MO
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
- Recommended
Missouri History Museum
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
- Recommended
Saint Louis Science Center
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
- Must visit
Gateway Arch National Park Grounds
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
- Must visit
Forest Park
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
- Recommended
Tower Grove Park
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
- Vegetarian
Toasted Ravioli
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
- Vegetarian
Gooey Butter Cake
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Bulrush
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Ted Drewes Frozen Custard
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Pappy's Smokehouse
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
FAQs: Bus from Winston Salem, NC to St. Louis, MO
Find answers to the most common questions about traveling from Winston Salem, NC to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Winston Salem, NC to St. Louis, MO
Most Winston Salem, NC to St. Louis, MO buses use the Winston Salem, W 5th St (Greyhound Bus Station) to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Winston Salem, NC and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Winston Salem
Arrival bus stations in St. Louis
Which Winston Salem, NC station do buses to St. Louis, MO leave from?
Buses from Winston Salem, NC to St. Louis, MO leave from Winston Salem, W 5th St (Greyhound Bus Station). The station is from Winston Salem, NC city centre at W 5th St, Winston-Salem, NC 27101, USA.
Winston Salem, W 5th St (Greyhound Bus Station)W 5th St, Winston-Salem, NC 27101, USA
City-centre transport
Getting to Winston Salem, W 5th St (Greyhound Bus Station) from Winston Salem city centre
TRUE
Winston Salem, W 5th St (Greyhound Bus Station) bus station facilities and services
Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).
Parking, taxis and toilets
Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.
Which St. Louis, MO station do buses from Winston Salem, NC arrive at?
Buses from Winston Salem, NC to St. Louis, MO arrive at St. Louis, S 15th St (Civic center). St. Louis, S 15th St (Civic center) is 0 miles (1 km) from St. Louis, MO city centre.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Most popular bus connections from Winston Salem, NC
More options for your journey from Winston Salem, NC to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Winston Salem, NC
Most popular bus connections to St. Louis, MO
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