- Must visit
Nasher Museum of Art
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
Cheapest price on Oct 24
€22
Average ticket price on Oct 24
€31
Fastest journey on Oct 24
1 h 50 m
Average journey duration on Oct 24
2 h 45 m
Buses on Oct 24
2
Distance
122 km
The best way to find a cheap bus ticket from Winston Salem, NC to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Winston Salem, NC to Durham, NC will cost around €31 if you buy it on the day, but the cheapest tickets can be found for only €22.
On Sat, Oct 24, we found 2 buses from Winston Salem, NC to Durham, NC, including 2 direct services.
On Sat, Oct 24 the direct buses cover the 122 km distance in an average of 2 h 45 m but if you time it right, some buses will get you there in just 1 h 50 m .
On Sat, Oct 24 the slowest buses will take 3 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Buses from Winston Salem, NC to Durham, NC run on average 1 times per day, taking around 2h 0m. Cheap bus tickets for this journey start at €16 if you book in advance.
There are 1 buses per day. The earliest bus runs at 04:55, the last at 19:58. The fastest bus covers the 75 miles (122 km) distance in 1h 50m.
Distance 75 miles (122 km) |
Average bus duration 2h 0m |
Cheapest ticket price €16 |
Buses per day 1 |
Direct buses 1 |
Fastest bus 1h 50m |
First bus 4:55 AM |
Last bus 7:58 PM |
Cheapest Month Jun |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 4 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Winston Salem, NC to Durham, NC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 11:10AM | Arrival Time 01:00PM | Duration 1h50 | Departure days Tue, Wed, Thu, Fri | Cheapest price €16 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 02:00PM | Duration 1h50 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price €20 |
Operator Greyhound | Departure Time 04:15PM | Arrival Time 07:55PM | Duration 3h40 | Departure days Sat | Cheapest price €40 |
Operator Greyhound | Departure Time 07:55PM | Arrival Time 03:00AM | Duration 7h05 | Departure days Mon, Wed | Cheapest price €31 |
The table below shows live departures for Winston Salem, NC to Durham, NC buses for today, Friday, October 23. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:10 AM Winston Salem, NC | 1h50 | 1:00 PM Durham, NC | 0 transfersDirect | |
![]() | 12:10 PM Winston Salem, NC | 1h50 | 2:00 PM Durham, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Durham, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Durham, NC trip today.
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
Hands-on science museum with aerospace, physics, wildlife, and family exhibits in downtown Durham.
Historic site and museum exploring Washington Duke, tobacco farming, and Durham's industrial origins.
Beloved public garden with terraces, woodland paths, and seasonal blooms, ideal for a scenic walk near Duke.
Lively downtown district for walking among warehouses, public art, music venues, and restored tobacco-era spaces.
Scenic riverside greenway for walking and cycling, connecting downtown with quiet stretches of restored nature.
Eastern North Carolina chopped pork barbecue with a tangy vinegar-pepper sauce. A defining regional staple widely loved across Durham and the Triangle.
Slow-cooked pork shoulder or whole hog, often served on a plate with slaw and hush puppies. It reflects the area’s deep barbecue tradition.
Fried cornmeal batter balls served with barbecue or seafood. They are a classic Southern side found on many Durham menus.
Refined restaurant showcasing seasonal North Carolina ingredients with polished service. Known for elevated Southern cooking and a stylish setting.
Beloved local bakery and café serving excellent pastries, breads, and coffee. A dependable stop for breakfast, lunch, or a quick snack.
Popular casual spot for inventive biscuit sandwiches, shrimp and grits, and Southern brunch favorites in a lively downtown atmosphere.
Moderate for a US college city; hotels and dining are mid-priced, transit is limited, but many casual meals and coffee shops are affordable.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Durham, NC.
Find answers to the most common questions about traveling from Winston Salem, NC to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

Most Winston Salem, NC to Durham, NC buses use the Winston Salem, W 5th St (Greyhound Bus Station) to Durham, W Pettigrew St (Greyhound Bus Station) station pair. Use this guide to compare Winston Salem, NC and Durham, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.
Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).
Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.
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