- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Cheapest price
€68
Average price
€69
Fastest journey
14 h
Average duration
19 h 18 m
Buses per day
2
Distance
371 km
The best way to find a cheap bus ticket from Winston Salem, NC to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Winston Salem, NC to Charleston, SC will cost around €69 if you buy it on the day, but the cheapest tickets can be found for only €68.
It's difficult to get from Winston Salem, NC to Charleston, SC without transferring at least once.
· · ·
·
·
· · · Take a bus from Winston Salem, NC to Charleston, SC and enjoy the approximately 230 miles (371 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 11:15, the last at 15:15.
Distance 230 miles (371 km) |
First bus 11:15 AM |
Last bus 3:15 PM |
High Season Jan - Mar |
Low Season Apr - Jun |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:40AM | Arrival Time 09:40PM | Duration 14h00 | Departure days Wed | Cheapest price €70 |
Operator Greyhound | Departure Time 10:20AM | Arrival Time 09:40PM | Duration 11h20 | Departure days Thu | Cheapest price €68 |
Operator Greyhound | Departure Time 05:55PM | Arrival Time 06:30PM | Duration 24h35 | Departure days Wed | Cheapest price €68 |
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Winston Salem, NC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Winston Salem, NC to Charleston, SC buses use the Winston Salem, W 5th St (Greyhound Bus Station) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Winston Salem, NC and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need