Winston Salem, NC to Charleston, SC bus with Greyhound

Sun, Mar 22
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2,000+ travel companies
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Alsa
Costa Verde
BlaBlaCar Bus
2,000+ travel companies
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Travel Information

Compare bus, train, and flight for Winston Salem, NC to Charleston, SC

Omio recommends booking the train as it is the most popular option from Winston Salem, NC to Charleston, SC among Omio's users. If you are prioritising price take the train with prices starting from $86. For those with little time consider booking a flight which can get you there in 4h 24m. The ticket price range depends on the travel mode: a train costs an average of $86, and a flight costs an average of $147.

Distance: 230 miles (371 km)

Compare bus with

Bus
Most popular
Train
Flight

$169

Average price

$134

Average price

Cheapest

$306

Average price

16h 8m

Average total duration

15h 38m

Onboard

+

30m

Additional time*

8h 20m

Average total duration

7h 50m

Onboard

+

30m

Additional time*

7h 24m

Average total duration

Fastest

4h 24m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Compare prices and tickets Winston Salem, NC to Charleston, SC by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Winston Salem, NC to Charleston, SC buses with Omio?

Greyhound operates all buses services from Winston Salem, NC to Charleston, SC.
Omio is an official ticket reseller for all your travel options from Winston Salem, NC to Charleston, SC.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Winston Salem, NC to Charleston, SC.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Winston Salem, NC to Charleston, SC.

Journey information

Overview: Bus from Winston Salem, NC to Charleston, SC

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Buses from Winston Salem, NC to Charleston, SC run on average 1 times per day, taking around 15h 38m. Cheap bus tickets for this journey start at $168 (€136) but you can travel from only $86 (€70) by train.

The earliest bus runs at 11:15, the last at 15:15. The fastest bus covers the 230 miles (371 km) distance in 8h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $86 (€70)
Distance
230 miles (371 km)
Average bus duration
15h 38m
Cheapest ticket price
$168 (€136)
Buses per day
1
Fastest bus
8h 40m
First bus
11:15
Last bus
15:15
High season
Oct - Dec
Low season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $86 (€70)

Bus providers: Greyhound from Winston Salem, NC to Charleston, SCYou can travel by bus between Winston Salem, NC to Charleston, SC with Greyhound for as low as $86 (€70). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
8h 40m
Cheapest Price
$168 (€136)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Winston Salem, NC to Charleston, SC

Find answers to the most common questions about traveling from Winston Salem, NC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Winston Salem, NC to Charleston, SC can start from as little as $168 (€136) when you book in advance. The average bus ticket price for Winston Salem, NC to Charleston, SC is $169 (€137) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Winston Salem, NC to Charleston, SC is 8h 40m to travel the 230 miles (371 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Winston Salem, NC to Charleston, SC leaves at 11:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Winston Salem, NC to Charleston, SC leaves at 3:15 PM.
There are 1 buses a day from Winston Salem, NC to Charleston, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Winston Salem, NC to Charleston, SC, you can count on Greyhound for the best way to get you to Charleston, SC. You can also check all possible bus companies who offer a service between Winston Salem, NC and Charleston, SC and compare the amenities they offer before buying a bus ticket.
A trip to Charleston, SC from Winston Salem, NC is worth doing but not as a day trip with a journey time of 8h 40m each way. Check with Omio app the best way to travel.
It's helpful to compare your options as there are 3 ways to travel between Winston Salem, NC and Charleston, SC including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Winston Salem, NC to Charleston, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Winston Salem, NC to Charleston, SC for bus company Greyhound.
Whether you can cancel your bus ticket from Winston Salem, NC to Charleston, SC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Winston Salem, NC to Charleston, SC.
Yes, the following luggage options are included when booking a bus ticket from Winston Salem, NC to Charleston, SC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Winston Salem, NC to Charleston, SC:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Winston Salem, NC to Charleston, SC.
You can reserve your seat on the bus from Winston Salem, NC to Charleston, SC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Winston Salem, NC to Charleston, SC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Winston Salem, NC to Charleston, SC with the following bus company: Greyhound.

More options for your journey from Winston Salem, NC to Charleston, SC

Here are some other resources that might have the information you need

Trains from Winston Salem, NC to Charleston, SC
Flights from Winston Salem, NC to Charleston, SC
Tickets and more information for coaches to Winston Salem, NC

Most popular buses to and from Charleston, SC and Winston Salem, NC

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