The cheapest and fastest buses from Winston Salem, NC to Charleston, SC
Cheapest price
$175
Average price
$175
Fastest journey
16 h 40 m
Average duration
16 h 40 m
Buses per day
1
Distance
371 km
The best way to find a cheap bus ticket from Winston Salem, NC to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Winston Salem, NC to Charleston, SC will cost around $175 if you buy it on the day, but the cheapest tickets can be found for only $175.
It's difficult to get from Winston Salem, NC to Charleston, SC without transferring at least 4 times.


Travel Information
Compare bus, train, and flight for Winston Salem, NC to Charleston, SC
Omio recommends booking the train as it is the most popular option from Winston Salem, NC to Charleston, SC among Omio's users. If you are prioritising price take the train with prices starting from €71. For those with little time consider booking a flight which can get you there in 3h 4m. The ticket price range depends on the travel mode: a train costs an average of €71, and a flight costs an average of €136.
Distance: 230 miles (371 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€139 Average price | €93 Average price Cheapest | €257 Average price |
16h 8m Average total duration 15h 38m Onboard + 30m Additional time* | 8h 20m Average total duration 7h 50m Onboard + 30m Additional time* | 6h 4m Average total duration Fastest 3h 4m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Winston Salem, NC to Charleston, SC bus times
The table below shows live departures for Winston Salem, NC to Charleston, SC buses for today, Wednesday, February 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:20 AM Winston Salem, NC | 9h53 | 8:13 PM Charleston, SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Winston Salem, NC to Charleston, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Winston Salem, NC to Charleston, SC buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Winston Salem, NC to Charleston, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Winston Salem, NC to Charleston, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Winston Salem, NC to Charleston, SC.
Journey information
Overview: Bus from Winston Salem, NC to Charleston, SC
Buses from Winston Salem, NC to Charleston, SC run on average 1 times per day, taking around 15h 38m. Cheap bus tickets for this journey start at $174 (€138) but you can travel from only $89 (€71) by train.
The earliest bus runs at 13:55, the last at 15:15. The fastest bus covers the 230 miles (371 km) distance in 8h 40m.
Distance 230 miles (371 km) |
Average bus duration 15h 38m |
Cheapest ticket price $174 (€138) |
Buses per day 1 |
Fastest bus 8h 40m |
First bus 13:55 |
Last bus 15:15 |
Bus providers: Greyhound from Winston Salem, NC to Charleston, SCYou can travel by bus between Winston Salem, NC to Charleston, SC with Greyhound for as low as $89 (€71). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Winston Salem, NC to Charleston, SC
Find answers to the most common questions about traveling from Winston Salem, NC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Winston Salem, NC to Charleston, SC
Most popular bus connections from Winston Salem, NC
More options for your journey from Winston Salem, NC to Charleston, SC
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