Winston Salem, NC to Charleston, SC bus with Greyhound

Sat, Sep 19
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Travel Information

Compare train and flight for Winston Salem, NC to Charleston, SC

Omio recommends booking the flight as it is the most popular option from Winston Salem, NC to Charleston, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €81 For those with little time, consider booking a flight, which has an average total journey time of 4h 55m. Average ticket prices depend on the travel mode: a bus costs an average of €81, while a flight costs an average of €510.

Distance: 230 miles (371 km)

Compare bus with

Bus
Most popular
Flight
Train

€81

Average price

Cheapest

€510

Average price

€96

Average price

13h 1m

Average total duration

12h 31m

Onboard

+

30m

Additional time*

4h 55m

Average total duration

Fastest

2h 55m

Onboard

+

2h 0m

Additional time*

8h 23m

Average total duration

7h 53m

Onboard

+

30m

Additional time*

Greyhound

Most popular bus company

American Airlines

Most popular airline

Amtrak

Most popular train company

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Winston Salem, NC to Charleston, SC is a bus with an average price of €81.

This is compared to other travel options from Winston Salem, NC to Charleston, SC:

A bus is €14 less than a train for this route with tickets for a train from Winston Salem, NC to Charleston, SC costing on average €96.

A bus is €428 less than a flight for this route with tickets for a flight from Winston Salem, NC to Charleston, SC costing on average €510.

The fastest way to travel from Winston Salem, NC to Charleston, SC is by flight with an average journey time of 2h 55m.

Other travel options to Charleston, SC take longer:

Train takes on average 7h 53m.

Bus takes on average 12h 31m.

It's helpful to compare your options as there are 2 ways to travel between Winston Salem, NC and Charleston, SC including taking a train and flight.
We recommend using the train as it is the most popular way to get from Winston Salem, NC to Charleston, SC among Omio's users.

Winston Salem, NC to Charleston, SC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
07:40AM
Arrival Time
09:50PM
Duration
14h10
Departure days
Fri
Cheapest price
101
Operator
Greyhound
Departure Time
02:55PM
Arrival Time
12:15PM
Duration
21h20
Departure days
Fri
Cheapest price
97

Live departures

Winston Salem, NC to Charleston, SC bus times

The table below shows live departures for Winston Salem, NC to Charleston, SC buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · 7:40 AM Winston Salem, W 5th St (Greyhound Bus Station), NC
14h10
9:50 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC1 transfer
Greyhound+FlixBusFlixBus+Greyhound2:55 PM Winston Salem, W 5th St (Greyhound Bus Station), NC
21h20
12:15 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Winston Salem, NC to Charleston, SC by train or flight

Compare train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 19
Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25

Why should you book Winston Salem, NC to Charleston, SC buses with Omio?

Greyhound operates all buses services from Winston Salem, NC to Charleston, SC.
Omio is an official ticket reseller for all your travel options from Winston Salem, NC to Charleston, SC.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and flight to ensure you get the best deal for traveling from Winston Salem, NC to Charleston, SC.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train and flight to find the ideal travel option from Winston Salem, NC to Charleston, SC.

Journey information

Overview: Bus from Winston Salem, NC to Charleston, SC

USAUSA
USAUSA
Icon of bus

Buses from Winston Salem, NC to Charleston, SC run on average 2 times per day, taking around 12h 31m. Cheap bus tickets for this journey start at €63 if you book in advance.

The earliest bus runs at 11:15, the last at 15:15. The fastest bus covers the 230 miles (371 km) distance in 11h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
230 miles (371 km)
Average bus duration
12h 31m
Cheapest ticket price
€63
Buses per day
2
Fastest bus
11h 35m
First bus
11:15 AM
Last bus
3:15 PM
High Season
Jul - Sep
Low Season
Oct - Dec
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Winston Salem, NC to Charleston, SCYou can travel by bus between Winston Salem, NC to Charleston, SC with Greyhound for as low as €63. When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
11h 35m
Cheapest Greyhound Price
€63
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Charleston, SC

Things to do in Charleston, SC

Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.

  • Must visit

The Charleston Museum

America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.

  • Must visit

Gibbes Museum of Art

Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.

  • Must visit

International African American Museum

Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.

US Dollar ($)

Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.

Average meal costs

Budget
$10-18 for fast food or casual lunch.
Mid-range
$25-45 per person for a restaurant meal.
Fine dining
$60+ per person for upscale restaurants.
Coffee
$4-6 for coffee or cappuccino.

Tipping culture

Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.

FAQs: Bus from Winston Salem, NC to Charleston, SC

Find answers to the most common questions about traveling from Winston Salem, NC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Winston Salem, NC to Charleston, SC can start from as little as €63 when you book in advance. The average bus ticket price for Winston Salem, NC to Charleston, SC is €81 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Winston Salem, NC to Charleston, SC is 11h 35m to travel the 230 miles (371 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Winston Salem, NC to Charleston, SC leaves at 11:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Winston Salem, NC to Charleston, SC leaves at 3:15 PM.
There are 2 buses a day from Winston Salem, NC to Charleston, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Winston Salem, NC to Charleston, SC, you can count on Greyhound for the best way to get you to Charleston, SC. You can also check all possible bus companies who offer a service between Winston Salem, NC and Charleston, SC and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Winston Salem, W 5th St (Greyhound Bus Station), NC, which is located around away from the city centre, and they get off the bus at Charleston, Gaynor Avenue (Greyhound Bus Station), SC, located 12 away from the city centre.
A trip to Charleston, SC from Winston Salem, NC is worth doing but not as a day trip with a journey time of 11h 35m each way. Check with Omio app the best way to travel.
It's helpful to compare your options as there are 2 ways to travel between Winston Salem, NC and Charleston, SC including taking a train and flight.
Yes, the following accessibility options are available when taking the bus from Winston Salem, NC to Charleston, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Winston Salem, NC to Charleston, SC for bus company Greyhound.
Whether you can cancel your bus ticket from Winston Salem, NC to Charleston, SC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Winston Salem, NC to Charleston, SC.
Yes, the following luggage options are included when booking a bus ticket from Winston Salem, NC to Charleston, SC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Winston Salem, NC to Charleston, SC:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Winston Salem, NC to Charleston, SC.
You can reserve your seat on the bus from Winston Salem, NC to Charleston, SC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Winston Salem, NC to Charleston, SC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Winston Salem, NC to Charleston, SC with the following bus company: Greyhound.
Since neither Winston Salem, NC nor Charleston, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Winston Salem, NC to Charleston, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Winston Salem, NC to Charleston, SC

Most Winston Salem, NC to Charleston, SC buses use the Winston Salem, W 5th St (Greyhound Bus Station) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Winston Salem, NC and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Winston Salem
Arrival bus stations in Charleston

Which Winston Salem, NC station do buses to Charleston, SC leave from?

Buses from Winston Salem, NC to Charleston, SC leave from Winston Salem, W 5th St (Greyhound Bus Station). The station is from Winston Salem, NC city centre at W 5th St, Winston-Salem, NC 27101, USA.
Winston Salem, W 5th St (Greyhound Bus Station)W 5th St, Winston-Salem, NC 27101, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Winston Salem, W 5th St (Greyhound Bus Station) from Winston Salem city centre

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Winston Salem, W 5th St (Greyhound Bus Station) bus station facilities and services

Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.

Tickets and information

Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).

Parking, taxis and toilets

Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.

More options for your journey from Winston Salem, NC to Charleston, SC

Here are some other resources that might have the information you need

Most popular buses to and from Charleston, SC and Winston Salem, NC

HomeBusesBuses in USAWinston Salem, NC to Charleston, SC bus

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