- Must visit
COSI
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
The best way to find a cheap bus ticket from Winston Salem, NC to Columbus, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Winston Salem, NC to Columbus, OH will cost around €60 if you buy it on the day, but the cheapest tickets can be found for only €60.
On Wed, Nov 04, we found 1 buses from Winston Salem, NC to Columbus, OH, including 1 direct services.
On Wed, Nov 04 the direct buses cover the 492 km distance in an average of 9 h 20 m but if you time it right, some buses will get you there in just 9 h 20 m .
On Wed, Nov 04 the slowest buses will take 9 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

|
| ||||||||||||

|
| ||||||||||||
Buses from Winston Salem, NC to Columbus, OH run on average 4 times per day, taking around 19h 42m. Cheap bus tickets for this journey start at €75 if you book in advance.
The earliest bus runs at 00:45, the last at 21:10. The fastest bus covers the 305 miles (492 km) distance in 15h 25m.
Distance 305 miles (492 km) |
Average bus duration 19h 42m |
Cheapest ticket price €75 |
Buses per day 4 |
Fastest bus 15h 25m |
First bus 12:45 AM |
Last bus 9:10 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Winston Salem, NC to Columbus, OH.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:55AM | Arrival Time 05:10PM | Duration 34h15 | Departure days Sat | Cheapest price €87 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 04:35AM | Duration 21h25 | Departure days Sat | Cheapest price €96 |
Operator Greyhound | Departure Time 02:55PM | Arrival Time 12:55PM | Duration 22h00 | Departure days Sat | Cheapest price €88 |
Operator Greyhound | Departure Time 04:35PM | Arrival Time 07:50PM | Duration 27h15 | Departure days Sat | Cheapest price €87 |
Operator FlixBus | Departure Time 05:55PM | Arrival Time 11:20PM | Duration 29h25 | Departure days Sat | Cheapest price €96 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 04:55PM | Duration 22h00 | Departure days Thu, Fri | Cheapest price €153 |
Operator Barons Bus | Departure Time 07:10PM | Arrival Time 04:30AM | Duration 9h20 | Departure days Tue, Wed, Sun | Cheapest price €60 |
Operator Greyhound | Departure Time 08:35PM | Arrival Time 11:50PM | Duration 27h15 | Departure days Fri | Cheapest price €175 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 12:50AM | Duration 27h15 | Departure days Mon | Cheapest price €175 |
The table below shows live departures for Winston Salem, NC to Columbus, OH buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:10 PM Winston Salem, NC | 9h20 | 4:30 AM Columbus, OH | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Columbus, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbus, OH trip today.
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
This leading art museum offers strong American and European collections, special exhibitions, and a notable sculpture garden.
Located on Ohio State's campus, this museum presents contemporary art and rotating exhibitions in an acclaimed modern building.
Columbus's best-known historic district has brick streets, restored homes, and a walkable atmosphere ideal for architecture lovers.
A scenic downtown riverfront park with fountains, trails, and skyline views, popular for walks, events, and photos.
This large botanical park is famous for seasonal displays, glasshouses, and the iconic Chihuly installation in the conservatory.
A tangy, tomato-based slaw served on hot dogs or sandwiches. It is a long-running Columbus comfort food linked to old local chili and diner culture.
A sweet, cinnamon-forward fried pastry sold at the Ohio State Fair since the early 1900s. It is one of central Ohio's most iconic fair treats.
A shredded chicken and cracker casserole common at Columbus-area potlucks and game days. It is a nostalgic Midwestern comfort dish in central Ohio.
Refined tasting-menu restaurant in the Short North with inventive seasonal cooking and one of the city's strongest fine dining reputations.
Acclaimed local brewery and gastropub serving creative beers and polished comfort food in a stylish but relaxed setting.
Beloved local pizzeria known for thin crust, square-cut Columbus-style pies in a casual neighborhood setting.
Moderate for a U.S. city: hotels, dining, and transit usually cost less than New York or Chicago, but more than smaller Midwest towns.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee at cafes if service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Columbus, OH.
Find answers to the most common questions about traveling from Winston Salem, NC to Columbus, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbus, OH, this guide helps you travel smarter and with confidence.

Most Winston Salem, NC to Columbus, OH buses use the Winston Salem, W 5th St (Greyhound Bus Station) to Columbus, E Town St (Bus Station) station pair, with some services arriving at Columbus, E Mound St (Akili Christian High School). Use this guide to compare Winston Salem, NC and Columbus, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.
Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).
Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.
Columbus, E Town St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Town St (Bus Station). ATMs are available at Columbus, E Town St (Bus Station).
Ticket office support is available at Columbus, E Town St (Bus Station).
Available at Columbus, E Town St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Town St (Bus Station): Wheelchair accessible bus platforms.
Columbus, E Mound St (Akili Christian High School) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Mound St (Akili Christian High School). ATMs are available at Columbus, E Mound St (Akili Christian High School).
Ticket office support is available at Columbus, E Mound St (Akili Christian High School).
Available at Columbus, E Mound St (Akili Christian High School): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Mound St (Akili Christian High School): Wheelchair accessible buses available.
Check bus stations information for Winston Salem, NC and Columbus, OH, including where buses depart and arrive on this route.
Here are some other resources that might have the information you need