- Must visit
COSI
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
Cheapest price
$74
Average price
$74
Fastest journey
9 h 20 m
Average duration
9 h 20 m
Buses per day
1
Distance
492 km
The best way to find a cheap bus ticket from Winston Salem, NC to Columbus, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Winston Salem, NC to Columbus, OH will cost around $74 if you buy it on the day, but the cheapest tickets can be found for only $74.
Of the 1 buses that leave Winston Salem, NC for Columbus, OH on Wed, Aug 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct buses cover the 492 km distance in an average of 9 h 20 m but if you time it right, some buses will get you there in just 9 h 20 m .
On Wed, Aug 05 the slowest buses will take 9 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from Winston Salem, NC to Columbus, OH among Omio's users. If you are prioritising price take the bus with prices starting from $187. For those with little time consider booking a flight which can get you there in 4h 7m. The ticket price range depends on the travel mode: a bus costs an average of $187, and a flight costs an average of $309.
Distance: 305 miles (492 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$211 Average price Cheapest | $317 Average price | $76 Average price (fuel + tolls) |
24h 31m Average total duration 24h 1m Onboard + 30m Additional time* | 7h 7m Average total duration Fastest 4h 7m Onboard + 3h 0m Additional time* | 5h 46m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Winston Salem, NC to Columbus, OH:
A bus is $106 (€86) less than a flight for this route with tickets for a flight from Winston Salem, NC to Columbus, OH costing on average $317 (€258).
Other travel options to Columbus, OH take longer:
Bus takes on average 24h 1m.
You'll arrive about -19h -15m sooner (24h 1m by bus vs 5h 46m by car) and save roughly $-135.32 (€-110.27) compared to fuel and tolls ($211 (€172) vs $76 (€62)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Barons Bus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:10PM | Arrival Time 09:45AM | Duration 21h35 | Departure days Sat | Cheapest price $227 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 04:55PM | Duration 22h00 | Departure days Thu, Fri | Cheapest price $187 |
Operator Barons Bus | Departure Time 07:10PM | Arrival Time 04:30AM | Duration 9h20 | Departure days Tue, Wed, Sun | Cheapest price $74 |
Operator Greyhound | Departure Time 08:35PM | Arrival Time 11:50PM | Duration 27h15 | Departure days Fri | Cheapest price $214 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 12:50AM | Duration 27h15 | Departure days Mon | Cheapest price $215 |
The table below shows live departures for Winston Salem, NC to Columbus, OH buses for tomorrow, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:10 PM Winston Salem, NC | 9h20 | 4:30 AM Columbus, OH | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Winston Salem, NC to Columbus, OH run on average 3 times per day, taking around 24h 1m. Cheap bus tickets for this journey start at $187 (€152) if you book in advance.
The earliest bus runs at 00:45, the last at 21:10. The fastest bus covers the 305 miles (492 km) distance in 21h 35m.
Distance 305 miles (492 km) |
Average bus duration 24h 1m |
Cheapest ticket price $187 (€152) |
Buses per day 3 |
Fastest bus 21h 35m |
First bus 12:45 AM |
Last bus 9:10 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jul - Sep |
Discover the best of Columbus, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbus, OH trip today.
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
This leading art museum offers strong American and European collections, special exhibitions, and a notable sculpture garden.
Located on Ohio State's campus, this museum presents contemporary art and rotating exhibitions in an acclaimed modern building.
Columbus's best-known historic district has brick streets, restored homes, and a walkable atmosphere ideal for architecture lovers.
A scenic downtown riverfront park with fountains, trails, and skyline views, popular for walks, events, and photos.
This large botanical park is famous for seasonal displays, glasshouses, and the iconic Chihuly installation in the conservatory.
A tangy, tomato-based slaw served on hot dogs or sandwiches. It is a long-running Columbus comfort food linked to old local chili and diner culture.
A sweet, cinnamon-forward fried pastry sold at the Ohio State Fair since the early 1900s. It is one of central Ohio's most iconic fair treats.
A shredded chicken and cracker casserole common at Columbus-area potlucks and game days. It is a nostalgic Midwestern comfort dish in central Ohio.
Refined tasting-menu restaurant in the Short North with inventive seasonal cooking and one of the city's strongest fine dining reputations.
Acclaimed local brewery and gastropub serving creative beers and polished comfort food in a stylish but relaxed setting.
Beloved local pizzeria known for thin crust, square-cut Columbus-style pies in a casual neighborhood setting.
Moderate for a U.S. city: hotels, dining, and transit usually cost less than New York or Chicago, but more than smaller Midwest towns.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee at cafes if service is provided.
Find answers to the most common questions about traveling from Winston Salem, NC to Columbus, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbus, OH, this guide helps you travel smarter and with confidence.

Most Winston Salem, NC to Columbus, OH buses use the Winston Salem, W 5th St (Greyhound Bus Station) to Columbus, E Mound St (Akili Christian High School) station pair, with some services arriving at Columbus, E Town St (Bus Station). Use this guide to compare Winston Salem, NC and Columbus, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.
Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).
Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.
Columbus, E Mound St (Akili Christian High School) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Mound St (Akili Christian High School). ATMs are available at Columbus, E Mound St (Akili Christian High School).
Ticket office support is available at Columbus, E Mound St (Akili Christian High School).
Available at Columbus, E Mound St (Akili Christian High School): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Mound St (Akili Christian High School): Wheelchair accessible buses available.
Columbus, E Town St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Town St (Bus Station). ATMs are available at Columbus, E Town St (Bus Station).
Ticket office support is available at Columbus, E Town St (Bus Station).
Available at Columbus, E Town St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Town St (Bus Station): Wheelchair accessible bus platforms.
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