- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price on Sep 01
$138
Average ticket price on Sep 01
$149
Fastest journey on Sep 01
13 h 30 m
Average journey duration on Sep 01
15 h 25 m
Buses on Sep 01
3
Distance
586 km
The best way to find a cheap bus ticket from Syracuse to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse to Rome will cost around $149 if you buy it on the day, but the cheapest tickets can be found for only $138.
It's difficult to get from Syracuse to Rome without transferring at least once.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Syracuse to Rome among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $101 For those with little time, consider booking a flight, which has an average total journey time of 4h 14m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $101, while a flight costs an average of $253.
Distance: 364 miles (586 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$101 Average price Cheapest | $114 Average price | $253 Average price |
13h 4m Average total duration 12h 34m Onboard + 30m Additional time* | 11h 41m Average total duration 11h 11m Onboard + 30m Additional time* | 4h 14m Average total duration Fastest 2h 14m Onboard + 2h 0m Additional time* |
0.6 - 1.5kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.8 - 3.5kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Syracuse to Rome:
A bus is $12 (€10) less than a train for this route with tickets for a train from Syracuse to Rome costing on average $114 (€92).
A bus is $152 (€123) less than a flight for this route with tickets for a flight from Syracuse to Rome costing on average $253 (€205).
Other travel options to Rome take longer:
Train takes on average 11h 11m.
Bus takes on average 12h 34m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:15AM | Arrival Time 09:30PM | Duration 14h15 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $70 |
Operator BlaBlaCar | Departure Time 07:30AM | Arrival Time 05:10PM | Duration 9h40 | Departure days Sun | Cheapest price $72 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 05:00PM | Duration 9h00 | Departure days Sun | Cheapest price $69 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 06:50PM | Duration 9h50 | Departure days Tue | Cheapest price $82 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 09:40AM | Duration 18h35 | Departure days Mon | Cheapest price $57 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 04:50AM | Duration 13h30 | Departure days Mon, Thu | Cheapest price $85 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 06:15AM | Duration 14h10 | Departure days Mon, Thu | Cheapest price $109 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 06:05AM | Duration 13h45 | Departure days Mon, Thu | Cheapest price $108 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 06:50AM | Duration 13h30 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $70 |
The table below shows live departures for Syracuse to Rome buses for today, Monday, August 31. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:05 PM Syracuse | 18h35 | 9:40 AM Rome | 0 transfersDirect | |
![]() | 3:20 PM Syracuse | 13h30 | 4:50 AM Rome | 0 transfersDirect | |
![]() | 4:05 PM Syracuse | 14h10 | 6:15 AM Rome | 0 transfersDirect | |
![]() | 4:20 PM Syracuse | 13h45 | 6:05 AM Rome | 0 transfersDirect | |
| Tuesday, September 1 | |||||
FlixBus · FlixBus | 7:15 AM Syracuse, Corso Umberto I | 14h15 | 9:30 PM Roma, Autostazione Tiburtina | 1 transfer | |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Syracuse to Rome run on average 2 times per day, taking around 12h 34m. Cheap bus tickets for this journey start at $38 (€30) but you can travel from only $31 (€25) by flight.
The earliest bus runs at 00:45, the last at 23:55. The fastest bus covers the 364 miles (586 km) distance in 11h 40m.
Distance 364 miles (586 km) |
Average bus duration 12h 34m |
Cheapest ticket price $38 (€30) |
Buses per day 2 |
Fastest bus 11h 40m |
First bus 12:45 AM |
Last bus 11:55 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Sat |
Best time to book 21 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Find answers to the most common questions about traveling from Syracuse to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Syracuse to Rome buses use the Syracuse, Corso Umberto I to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Syracuse and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Here are some other resources that might have the information you need