- Must visit
Pinacoteca di Brera
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
Cheapest price on Sep 19
€99
Average ticket price on Sep 19
€125
Fastest journey on Sep 19
20 h 25 m
Average journey duration on Sep 19
21 h 39 m
Buses on Sep 19
5
Distance
1061 km
The best way to find a cheap bus ticket from Syracuse to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse to Milan will cost around €125 if you buy it on the day, but the cheapest tickets can be found for only €99.
It's difficult to get from Syracuse to Milan without transferring at least once.
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FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Syracuse to Milan among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €119 For those with little time, consider booking a train, which has an average total journey time of 17h 35m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.3 - 1.0kg. Average ticket prices depend on the travel mode: a bus costs an average of €119, while a train costs an average of €146.
Distance: 659 miles (1061 km)
| Bus | Most popular Train |
|---|---|
€119 Average price Cheapest | €146 Average price |
20h 57m Average total duration 20h 27m Onboard + 30m Additional time* | 17h 35m Average total duration Fastest 17h 5m Onboard + 30m Additional time* |
1.1 - 2.6kg CO2 emissions | 0.3 - 1.0kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Syracuse to Milan:
A bus is €27 less than a train for this route with tickets for a train from Syracuse to Milan costing on average €146.
A bus is €64 less than a flight for this route with tickets for a flight from Syracuse to Milan costing on average €183.
Other travel options to Milan take longer:
Train takes on average 17h 5m.
Bus takes on average 20h 27m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:15AM | Arrival Time 09:49AM | Duration 28h34 | Departure days Thu, Sun | Cheapest price €68 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 05:55AM | Duration 22h40 | Departure days Mon, Wed, Fri, Sat | Cheapest price €71 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 11:40AM | Duration 20h35 | Departure days Tue, Thu, Sun | Cheapest price €64 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 11:45AM | Duration 20h25 | Departure days Tue, Thu, Sun | Cheapest price €76 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 12:45PM | Duration 20h40 | Departure days Tue, Thu, Sun | Cheapest price €65 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 12:45PM | Duration 20h25 | Departure days Tue, Thu, Sun | Cheapest price €63 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 03:15PM | Duration 21h55 | Departure days Mon, Wed, Fri, Sat | Cheapest price €58 |
The table below shows live departures for Syracuse to Milan buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 5:20 PM Syracuse, Corso Umberto I | 20h25 | 1:45 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:20 PM Syracuse, Corso Umberto I | 21h55 | 3:15 PM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:20 PM Syracuse, Corso Umberto I | 21h15 | 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
| Saturday, September 19 | |||||
FlixBus · FlixBus | 7:15 AM Syracuse, Corso Umberto I | 22h40 | 5:55 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 7:15 AM Syracuse, Corso Umberto I | 22h00 | 5:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Syracuse to Milan run on average 4 times per day, taking around 20h 27m. Cheap bus tickets for this journey start at €56 but you can travel from only €38 by train.
The earliest bus runs at 04:38, the last at 22:18. The fastest bus covers the 659 miles (1061 km) distance in 19h 0m.
Distance 659 miles (1061 km) |
Average bus duration 20h 27m |
Cheapest ticket price €56 |
Buses per day 4 |
Fastest bus 19h 0m |
First bus 4:38 AM |
Last bus 10:18 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Sun |
Best time to book 1 day |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
This contemporary art museum near Porta Romana presents rotating exhibitions in a striking former industrial distillery complex.
Italy’s leading science museum is set in a former monastery and features Leonardo galleries, trains, aircraft, and a submarine.
Milan’s central square frames the cathedral and major civic buildings, making it the city’s essential meeting point and photo stop.
This artistic district offers charming lanes, Brera atmosphere, boutiques, and easy access to galleries and evening strolls.
A large landscaped park behind the castle, perfect for walks, skyline views, and reaching landmarks like the Arch of Peace.
Saffron risotto cooked with butter, stock and cheese. It is Milan's signature dish, linked to the city's love of rich northern Italian rice cookery.
Breaded veal cutlet fried in butter until golden. A classic Milanese main, prized for its simple preparation and long-standing local tradition.
Slow-braised veal shanks with vegetables, wine and broth, often finished with gremolata. A hearty Lombard specialty commonly paired with risotto.
Three-Michelin-star fine dining by Enrico Bartolini in MUDEC. Expect refined Italian tasting menus in a polished contemporary setting.
Historic Milanese restaurant near the Duomo, famous for risotto and cotoletta. Traditional, elegant rooms and a strong local culinary identity.
Long-running local favorite for classic Milanese cuisine, especially risotto and ossobuco. Warm, old-school atmosphere in the Brera area.
Moderate for Western Europe. Hotels and central dining can be pricey, but transit is affordable and budget meals, aperitivo deals, and local cafes help keep daily costs reasonable.
Tipping is modest. Service may be included. Round up or leave €1-2 at cafes, 5-10% for good restaurant service, and round up taxi fares.
Official public transport app
Orio al Serio, Milan Bergamo Airport (Bus station) -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Syracuse to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

Most Syracuse to Milan buses use the Syracuse, Corso Umberto I to Milano, Autostazione Lampugnano station pair, with some services arriving at Milano, San Donato - Settore B (Viale Giuseppe Impastato). Use this guide to compare Syracuse and Milan bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
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