The cheapest and fastest buses from Syracuse to Milan
Cheapest price
$133
Average price
$138
Fastest journey
20 h 35 m
Average duration
21 h 27 m
Buses per day
3
Distance
1061 km
The best way to find a cheap bus ticket from Syracuse to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse to Milan will cost around $138 if you buy it on the day, but the cheapest tickets can be found for only $133.
It's difficult to get from Syracuse to Milan without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBusTravel Information
Compare bus, train, and flight for Syracuse to Milan
Omio recommends booking the train as it is the most popular option from Syracuse to Milan among Omio's users. If you are prioritising price take the train with prices starting from €48. For those with little time consider booking a flight which can get you there in 1h 50m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 1.0kg. The ticket price range depends on the travel mode: a train costs an average of €48, and a bus costs an average of €51.
Distance: 659 miles (1061 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€143 Average price | €137 Average price Cheapest | €143 Average price |
18h 55m Average total duration 18h 25m Onboard + 30m Additional time* | 14h 38m Average total duration 14h 8m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* |
1.1 - 2.6kg CO2 emissions | 0.3 - 1.0kg CO2 emissions Lowest | 3.2 - 6.4kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Syracuse to Milan Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:05PM | Arrival Time 01:40PM | Duration 20h35 | Departure days Mon, Wed, Sat, Sun | Cheapest price $92 |
Live departures
Syracuse to Milan bus times
The table below shows live departures for Syracuse to Milan buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 4:05 PM Syracuse, Corso Umberto I | 22h15 | 2:20 PM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus | 4:05 PM Syracuse, Corso Umberto I | 20h35 | 12:40 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:05 PM Syracuse, Corso Umberto I | 21h30 | 1:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse to Milan by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Journey information
Overview: Bus from Syracuse to Milan
Buses from Syracuse to Milan run on average 4 times per day, taking around 18h 25m. Cheap bus tickets for this journey start at $64 (€51) but you can travel from only $25 (€20) by flight.
The earliest bus runs at 00:10, the last at 21:50. The fastest bus covers the 659 miles (1061 km) distance in 14h 44m.
Distance 659 miles (1061 km) |
Average bus duration 18h 25m |
Cheapest ticket price $64 (€51) |
Buses per day 4 |
Fastest bus 14h 44m |
First bus 00:10 |
Last bus 21:50 |
Bus providers: FlixBus, BlaBlaCar from Syracuse to MilanYou can travel by bus between Syracuse to Milan with FlixBus, BlaBlaCar for as low as $25 (€20). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from Syracuse to Milan
Find answers to the most common questions about traveling from Syracuse to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Duomo di Milano, an iconic Gothic cathedral known for its intricate facade and panoramic rooftop views
- Galleria Vittorio Emanuele II, a historic shopping arcade featuring luxury brands and elegant architecture
- Castello Sforzesco, a Renaissance fortress housing museums and art collections
- Santa Maria delle Grazie, a church famous for housing Leonardo da Vinci's The Last Supper
- Teatro alla Scala, a world-renowned opera house celebrated for its exceptional acoustics and performances.
- Visit the Duomo di Milano, an iconic Gothic cathedral with stunning architecture and panoramic rooftop views
- Explore The Last Supper, Leonardo da Vinci's renowned mural located in the Convent of Santa Maria delle Grazie
- Stroll through Galleria Vittorio Emanuele II, a historic shopping arcade with luxury boutiques and elegant cafes
- Discover Sforza Castle, a grand fortress housing several museums and art collections
- Relax in Sempione Park, a large green space perfect for leisurely walks and picnics near the city center.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
To find the cheapest bus tickets for your trip from Syracuse to Milan, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- Larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Syracuse to Milan
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Syracuse
More options for your journey from Syracuse to Milan
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