The cheapest and fastest buses from Syracuse to Milan
Cheapest price
$75
Average price
$75
Fastest journey
20 h 35 m
Average duration
20 h 35 m
Buses per day
1
Distance
1061 km
The best way to find a cheap bus ticket from Syracuse to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse to Milan will cost around $75 if you buy it on the day, but the cheapest tickets can be found for only $75.
Of the 1 buses that leave Syracuse for Milan on Sun, Mar 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 22 the direct buses cover the 1061 km distance in an average of 20 h 35 m but if you time it right, some buses will get you there in just 20 h 35 m .
On Sun, Mar 22 the slowest buses will take 20 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Syracuse to Milan
Omio recommends booking the train as it is the most popular option from Syracuse to Milan among Omio's users. If you are prioritising price take the flight with prices starting from $19. For those with little time consider booking a flight which can get you there in 1h 50m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 1.0kg. The ticket price range depends on the travel mode: a flight costs an average of $19, and a train costs an average of $57.
Distance: 659 miles (1061 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$128 Average price | $133 Average price | $97 Average price Cheapest |
18h 57m Average total duration 18h 27m Onboard + 30m Additional time* | 14h 35m Average total duration 14h 5m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* |
1.1 - 2.6kg CO2 emissions | 0.3 - 1.0kg CO2 emissions Lowest | 3.2 - 6.4kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Syracuse to Milan Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:20PM | Arrival Time 01:45PM | Duration 20h25 | Departure days Wed, Fri, Sat | Cheapest price $71 |
Live departures
Syracuse to Milan bus times
The table below shows live departures for Syracuse to Milan buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 4:20 PM Syracuse, Corso Umberto I | 22h00 | 2:20 PM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:20 PM Syracuse, Corso Umberto I | 21h15 | 1:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus | 4:20 PM Syracuse, Corso Umberto I | 20h25 | 12:45 PM Milano, Autostazione Lampugnano | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse to Milan by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Syracuse to Milan buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Syracuse to Milan.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Syracuse to Milan.
Journey information
Overview: Bus from Syracuse to Milan
Buses from Syracuse to Milan run on average 3 times per day, taking around 18h 27m. Cheap bus tickets for this journey start at $53 (€43) but you can travel from only $19 (€15) by flight.
The earliest bus runs at 04:38, the last at 22:18. The fastest bus covers the 659 miles (1061 km) distance in 20h 35m.
Distance 659 miles (1061 km) |
Average bus duration 18h 27m |
Cheapest ticket price $53 (€43) |
Buses per day 3 |
Fastest bus 20h 35m |
First bus 04:38 |
Last bus 22:18 |
Bus providers: FlixBus, BlaBlaCar from Syracuse to MilanYou can travel by bus between Syracuse to Milan with FlixBus, BlaBlaCar for as low as $19 (€15). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from Syracuse to Milan
Find answers to the most common questions about traveling from Syracuse to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Duomo di Milano, an iconic Gothic cathedral known for its intricate facade and panoramic rooftop views
- Galleria Vittorio Emanuele II, a historic shopping arcade featuring luxury brands and elegant architecture
- Castello Sforzesco, a Renaissance fortress housing museums and art collections
- Santa Maria delle Grazie, a church famous for housing Leonardo da Vinci's The Last Supper
- Teatro alla Scala, a world-renowned opera house celebrated for its exceptional acoustics and performances.
- Visit the Duomo di Milano, an iconic Gothic cathedral with stunning architecture and panoramic rooftop views
- Explore The Last Supper, Leonardo da Vinci's renowned mural located in the Convent of Santa Maria delle Grazie
- Stroll through Galleria Vittorio Emanuele II, a historic shopping arcade with luxury boutiques and elegant cafes
- Discover Sforza Castle, a grand fortress housing several museums and art collections
- Relax in Sempione Park, a large green space perfect for leisurely walks and picnics near the city center.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Syracuse to Milan
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Syracuse
More options for your journey from Syracuse to Milan
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