- Must visit
Pinacoteca di Brera
Milan’s premier art gallery, known for Italian masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$112
Average price
$154
Fastest journey
20 h 25 m
Average duration
21 h 39 m
Buses per day
5
Distance
1061 km
The best way to find a cheap bus ticket from Syracuse to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse to Milan will cost around $154 if you buy it on the day, but the cheapest tickets can be found for only $112.
It's difficult to get from Syracuse to Milan without transferring at least once.
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FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Syracuse to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $52. For those with little time consider booking a train which can get you there in 14h 4m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 1.0kg. The ticket price range depends on the travel mode: a bus costs an average of $52, and a train costs an average of $51.
Distance: 659 miles (1061 km)
| Bus | Most popular Train |
|---|---|
$93 Average price Cheapest | $137 Average price |
18h 54m Average total duration 18h 24m Onboard + 30m Additional time* | 14h 34m Average total duration Fastest 14h 4m Onboard + 30m Additional time* |
1.1 - 2.6kg CO2 emissions | 0.3 - 1.0kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Syracuse to Milan:
A bus is $44 (€36) less than a train for this route with tickets for a train from Syracuse to Milan costing on average $137 (€112).
Other travel options to Milan take longer:
Train takes on average 14h 4m.
Bus takes on average 18h 24m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:15AM | Arrival Time 09:49AM | Duration 28h34 | Departure days Wed | Cheapest price $87 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 05:55AM | Duration 22h40 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $115 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 04:30PM | Duration 25h25 | Departure days Wed | Cheapest price $88 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 11:45AM | Duration 20h25 | Departure days Wed | Cheapest price $104 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 12:45PM | Duration 20h40 | Departure days Wed | Cheapest price $64 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 12:45PM | Duration 20h25 | Departure days Wed | Cheapest price $91 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 01:45PM | Duration 20h25 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $91 |
The table below shows live departures for Syracuse to Milan buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 5:20 PM Syracuse, Corso Umberto I | 20h25 | 1:45 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:20 PM Syracuse, Corso Umberto I | 21h55 | 3:15 PM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:20 PM Syracuse, Corso Umberto I | 21h15 | 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
| Saturday, June 20 | |||||
FlixBus · FlixBus | 7:15 AM Syracuse, Corso Umberto I | 22h00 | 5:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 7:15 AM Syracuse, Corso Umberto I | 22h40 | 5:55 AM Milano, Autostazione Lampugnano | 1 transfer | |
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Syracuse to Milan run on average 3 times per day, taking around 18h 24m. Cheap bus tickets for this journey start at $52 (€43) but you can travel from only $51 (€42) by train.
The earliest bus runs at 04:38, the last at 22:18. The fastest bus covers the 659 miles (1061 km) distance in 20h 25m.
Distance 659 miles (1061 km) |
Average bus duration 18h 24m |
Cheapest ticket price $52 (€43) |
Buses per day 3 |
Fastest bus 20h 25m |
First bus 4:38 AM |
Last bus 10:18 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Fri |
Best time to book 21 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
Milan’s premier art gallery, known for Italian masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Museum entry for Leonardo’s The Last Supper, one of the world’s most famous artworks and a priority booking site in Milan.
Major museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist collections and rooftop views.
Milan’s canal district, known for waterside walks, lively atmosphere, and highly photogenic bridges and reflections.
Charming central neighborhood with elegant streets, galleries, boutiques, and a classic Milanese artistic atmosphere.
Milan’s main square and the city’s most important urban landmark, ideal for first-time visitors and classic views.
Milan’s signature saffron risotto, rich with butter and cheese, prized for its golden color and elegant flavor.
A traditional breaded veal cutlet, fried until crisp. It is one of the city’s most iconic and historic main dishes.
Braised veal shank, often served with risotto alla Milanese. It is a classic Lombard comfort dish with deep, slow-cooked flavor.
Iconic casual spot famous for panzerotti, beloved by locals and visitors for quick, affordable bites near the Duomo.
Well-known modern Milanese restaurant celebrated for refined local dishes such as mondeghili and risotto in a stylish setting.
Historic traditional trattoria serving classic Milanese and Lombard dishes in an old-world, elegant atmosphere.
Prices are high by Italian standards, especially for hotels and central dining, but budget cafés and aperitivo deals help control daily costs.
Tipping is modest. Service may be included or a coperto charged. Round up or leave 5-10% for very good restaurant service; small change for taxis and cafés is enough.
Official public transport app
Orio Al Serio Airport, Bergamo -> Milano Centrale
Find answers to the most common questions about traveling from Syracuse to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

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