- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price
$44
Average price
$44
Fastest journey
4 h
Average duration
4 h
Buses per day
1
Distance
204 km
The best way to find a cheap bus ticket from Syracuse to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse to Palermo will cost around $44 if you buy it on the day, but the cheapest tickets can be found for only $44.
It's difficult to get from Syracuse to Palermo without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Syracuse to Palermo among Omio's users. If you are prioritising price take the train with prices starting from $24. For those with little time consider booking a bus which can get you there in 3h 31m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a train costs an average of $24, and a bus costs an average of $20.
Distance: 126 miles (204 km)
Most popular Bus | Train |
|---|---|
$30 Average price | $25 Average price Cheapest |
4h 1m Average total duration Fastest 3h 31m Onboard + 30m Additional time* | 5h 30m Average total duration 5h 0m Onboard + 30m Additional time* |
0.2 - 0.5kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Syracuse to Palermo:
A train is $5 (€4) less than a bus for this route with tickets for a bus from Syracuse to Palermo costing on average $30 (€25).
Other travel options to Palermo take longer:
Train takes on average 5h 0m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:15AM | Arrival Time 01:15PM | Duration 8h00 | Departure days Tue | Cheapest price $32 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 01:15PM | Duration 7h00 | Departure days Tue | Cheapest price $35 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 11:15AM | Duration 4h00 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $39 |
Operator BlaBlaCar | Departure Time 08:20AM | Arrival Time 11:30AM | Duration 3h10 | Departure days Sat | Cheapest price $24 |
The table below shows live departures for Syracuse to Palermo buses for tomorrow, Wednesday, July 15. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:15 AM Syracuse, Corso Umberto I | 4h00 | 11:15 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Syracuse to Palermo run on average 4 times per day, taking around 3h 31m. Cheap bus tickets for this journey start at $20 (€16) if you book in advance.
There are 2 buses per day. The earliest bus runs at 03:17, the last at 20:05. The fastest bus covers the 126 miles (204 km) distance in 3h 45m.
Distance 126 miles (204 km) |
Average bus duration 3h 31m |
Cheapest ticket price $20 (€16) |
Buses per day 4 |
Direct buses 2 |
Fastest bus 3h 45m |
First bus 3:17 AM |
Last bus 8:05 PM |
Cheapest Month Jun |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Sat |
Best time to book 63 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Find answers to the most common questions about traveling from Syracuse to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

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