The cheapest and fastest buses from Rome to Syracuse
Cheapest price
$92
Average price
$99
Fastest journey
13 h
Average duration
15 h 28 m
Buses per day
2
Distance
586 km
The best way to find a cheap bus ticket from Rome to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Syracuse will cost around $99 if you buy it on the day, but the cheapest tickets can be found for only $92.
It's difficult to get from Rome to Syracuse without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBusTravel Information
Compare bus, train, and flight for Rome to Syracuse
Omio recommends booking the train as it is the most popular option from Rome to Syracuse among Omio's users. If you are prioritising price take the flight with prices starting from $29. For those with little time consider booking a flight which can get you there in 1h 17m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a flight costs an average of $29, and a bus costs an average of $33.
Distance: 364 miles (586 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$96 Average price | $95 Average price | $51 Average price Cheapest |
12h 53m Average total duration 12h 23m Onboard + 30m Additional time* | 10h 22m Average total duration 9h 52m Onboard + 30m Additional time* | 4h 17m Average total duration Fastest 1h 17m Onboard + 3h 0m Additional time* |
0.6 - 1.5kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.8 - 3.5kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Rome to Syracuse Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 08:40PM | Duration 19h55 | Departure days Wed | Cheapest price $36 |
Operator FlixBus | Departure Time 02:45AM | Arrival Time 08:40PM | Duration 17h55 | Departure days Mon, Fri, Sat, Sun | Cheapest price $58 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 08:40PM | Duration 26h25 | Departure days Wed | Cheapest price $36 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 09:40AM | Duration 13h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 08:40PM | Duration 20h55 | Departure days Wed | Cheapest price $62 |
Live departures
Rome to Syracuse bus times
The table below shows live departures for Rome to Syracuse buses for today, Sunday, March 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 1:45 AM Roma, Autostazione Tiburtina | 17h55 | 7:40 PM Syracuse, Corso Umberto I | 2 transfers | |
FlixBus · FlixBus | 7:15 PM Roma, Autostazione Tiburtina | 13h25 | 8:40 AM Syracuse, Corso Umberto I | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Syracuse by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Why should you book Rome to Syracuse buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Rome to Syracuse.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Rome to Syracuse.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Rome to Syracuse.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Rome to Syracuse.
Journey information
Overview: Bus from Rome to Syracuse
Buses from Rome to Syracuse run on average 2 times per day, taking around 12h 23m. Cheap bus tickets for this journey start at $33 (€26) but you can travel from only $29 (€23) by flight.
The earliest bus runs at 01:15, the last at 23:55. The fastest bus covers the 364 miles (586 km) distance in 13h 25m.
Distance 364 miles (586 km) |
Average bus duration 12h 23m |
Cheapest ticket price $33 (€26) |
Buses per day 2 |
Fastest bus 13h 25m |
First bus 01:15 |
Last bus 23:55 |
Bus providers: FlixBus, Itabus, BlaBlaCar from Rome to SyracuseYou can travel by bus between Rome to Syracuse with FlixBus, Itabus, BlaBlaCar for as low as $29 (€23). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
BlaBlaCar
FAQs: Bus from Rome to Syracuse
Find answers to the most common questions about traveling from Rome to Syracuse by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Neapolis Archaeological Park, a historical site featuring the Greek Theatre and Roman Amphitheatre
- Ortigia Island, the historical heart of Syracuse known for its Baroque architecture and charming streets
- Syracuse Cathedral, a stunning cathedral built on the remains of a Greek temple
- Temple of Apollo, one of the oldest Doric temples in Sicily, offering insight into ancient Greek architecture
- Castello Maniace, a 13th-century castle offering panoramic views of the sea and city.
- Ear of Dionysius, experience the unique acoustics of this limestone cave
- Aretusa Fountain, admire the legendary freshwater spring surrounded by papyrus plants
- Explore the vibrant local markets, where you can taste and purchase fresh Sicilian produce
- Take a boat tour around Ortigia Island, offering a unique perspective of the city from the water
- Enjoy a traditional Sicilian cooking class, learning to make local dishes with fresh ingredients.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Rome to Syracuse
More options for your journey from Rome to Syracuse
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