- Must visit
Paolo Orsi Regional Archaeological Museum
Leading archaeology museum with superb Greek and Roman finds, essential for understanding ancient Syracuse and eastern Sicily.
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The cheapest and fastest buses from Rome to Syracuse
Showing times, prices and bookable tickets for Aug 29
Cheapest price on Aug 29
€67
Average ticket price on Aug 29
€67
Fastest journey on Aug 29
12 h 15 m
Average journey duration on Aug 29
12 h 15 m
Buses on Aug 29
1
Distance
586 km
Cheap tickets
The best way to find a cheap bus ticket from Rome to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Syracuse will cost around €67 if you buy it on the day, but the cheapest tickets can be found for only €67.
Fast buses
It's difficult to get from Rome to Syracuse without transferring at least once.
FlixBus · FlixBus9:00 PM12h15Roma, Autostazione Tiburtina9:15 AMSyracuse, Corso Umberto I€671One-way1 transfer
- FlixBus · FlixBus9:00 PM12h15Roma, Autostazione Tiburtina9:15 AMSyracuse, Corso Umberto I€671One-way1 transfer
Travel Information
Compare bus, train, and flight for Rome to Syracuse
Omio recommends booking the train as it is the most popular option from Rome to Syracuse among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €79 For those with little time, consider booking a flight, which has an average total journey time of 3h 57m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of €79, while a flight costs an average of €163.
Distance: 364 miles (586 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€79 Average price Cheapest | €93 Average price | €163 Average price |
13h 28m Average total duration 12h 58m Onboard + 30m Additional time* | 12h 24m Average total duration 11h 54m Onboard + 30m Additional time* | 3h 57m Average total duration Fastest 1h 57m Onboard + 2h 0m Additional time* |
0.6 - 1.5kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.8 - 3.5kg CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Rome to Syracuse is a bus with an average price of €79.
This is compared to other travel options from Rome to Syracuse:
A bus is €14 less than a train for this route with tickets for a train from Rome to Syracuse costing on average €93.
A bus is €84 less than a flight for this route with tickets for a flight from Rome to Syracuse costing on average €163.
The fastest way to travel from Rome to Syracuse is by flight with an average journey time of 1h 57m.
Other travel options to Syracuse take longer:
Train takes on average 11h 54m.
Bus takes on average 12h 58m.
It's helpful to compare your options as there are 3 ways to travel between Rome and Syracuse including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Rome to Syracuse among Omio's users.
Rome to Syracuse Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:00PM | Arrival Time 09:15AM | Duration 12h15 | Departure days Everyday | Cheapest price €47 |
Live departures
Rome to Syracuse bus times
The table below shows live departures for Rome to Syracuse buses for today, Friday, August 28. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 12h15 | 9:15 AM Syracuse, Corso Umberto I | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Syracuse by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rome to Syracuse buses with Omio?
FlixBus as well as Itabus offer buses services from Rome to Syracuse.
Omio is an official ticket reseller for all your travel options from Rome to Syracuse.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Rome to Syracuse.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Rome to Syracuse.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Rome to Syracuse.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Rome to Syracuse.
Journey information
Overview: Bus from Rome to Syracuse
ItalyItaly
Buses from Rome to Syracuse run on average 1 times per day, taking around 12h 58m. Cheap bus tickets for this journey start at €28 but you can travel from only €21 by flight.
The earliest bus runs at 00:45, the last at 23:55. The fastest bus covers the 364 miles (586 km) distance in 11h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €21
Distance 364 miles (586 km) |
Average bus duration 12h 58m |
Cheapest ticket price €28 |
Buses per day 1 |
Fastest bus 11h 55m |
First bus 12:45 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Mon |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €21
Bus providers: FlixBus from Rome to SyracuseYou can travel by bus between Rome to Syracuse with FlixBus for as low as €35. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
11h 55m
Cheapest Price
€28
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Syracuse
Things to do in Syracuse
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
- Recommended
Bellomo Palace Regional Gallery
Gallery inside Palazzo Bellomo showing medieval and Baroque art, including Antonello da Messina's celebrated Annunciation.
- Recommended
Archimedes Technopark and Leonardo da Vinci Museum
Interactive science museum focused on Archimedes and Leonardo, engaging for families and visitors curious about inventions.
- Must visit
Ortigia
Syracuse's historic island center, packed with Baroque lanes, seafront walks, ancient ruins, and a vibrant local atmosphere.
- Must visit
Piazza Duomo
Grand limestone square framed by the cathedral and palaces, one of Sicily's most elegant and memorable urban spaces.
- Must visit
Fonte Aretusa
Freshwater spring beside the sea linked to myth, famous for papyrus plants and its central place in Ortigia legends.
- Vegetarian
Pasta alla Norma
Pasta with fresh tomato sauce, fried eggplant, ricotta salata and basil. A classic Sicilian dish tied to nearby Catania and widely loved in Syracuse.
Arancini
Rice balls stuffed with ragù, cheese or butter, then breaded and fried. A staple Sicilian street food eaten across Syracuse.
Pesce Fritto
Small fried fish, often anchovies or whitebait, served simply with lemon. It reflects Syracuse's strong seafood tradition and daily catch.
Don Camillo
Refined Michelin-starred dining on Ortigia with creative Sicilian tasting menus, elegant service and a romantic historic setting.
Caseificio Borderi
Historic market stop famous for sandwiches, charcuterie, cheese and quick Sicilian bites amid the bustling Ortigia food market.
Osteria da Mariano
Well-known Ortigia seafood restaurant serving local fish, pasta and Sicilian classics in a polished but relaxed atmosphere.
Euro (€)
Moderate for Sicily. Dining and hotels are often cheaper than Rome or Milan, while summer stays in Ortigia and tourist dining can raise costs. Local buses are low cost.
Average meal costs
- Budget
- €8-15 for pizza, panini, or casual takeaway.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale seafood or tasting menus.
- Coffee
- €1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is often included or minimal. Round up or leave 5-10% at restaurants for good service. Taxis are usually rounded up. In cafes, small change is enough.
FAQs: Bus from Rome to Syracuse
Find answers to the most common questions about traveling from Rome to Syracuse by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rome to Syracuse can start from as little as €28 when you book in advance. The average bus ticket price for Rome to Syracuse is €79 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rome to Syracuse is 11h 55m to travel the 364 miles (586 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rome to Syracuse leaves at 12:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Syracuse leaves at 11:55 PM.
There are 1 buses a day from Rome to Syracuse which require at least one change with FlixBus, Itabus, BlaBlaCar. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Rome to Syracuse, you can count on FlixBus, Itabus, BlaBlaCar for the best way to get you to Syracuse. You can also check all possible bus companies who offer a service between Rome and Syracuse and compare the amenities they offer before buying a bus ticket.
A trip to Syracuse from Rome is worth doing but not as a day trip with a journey time of 11h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Rome to Syracuse is May.
It's helpful to compare your options as there are 3 ways to travel between Rome and Syracuse including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Rome to Syracuse:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
Yes, there are bathrooms on board the bus from Rome to Syracuse for bus company FlixBus, Itabus.
Some of the most interesting sights to explore in Syracuse are:
- Neapolis Archaeological Park, a historical site featuring the Greek Theatre and Roman Amphitheatre
- Ortigia Island, the historical heart of Syracuse known for its Baroque architecture and charming streets
- Syracuse Cathedral, a stunning cathedral built on the remains of a Greek temple
- Temple of Apollo, one of the oldest Doric temples in Sicily, offering insight into ancient Greek architecture
- Castello Maniace, a 13th-century castle offering panoramic views of the sea and city.
The best things to do in Syracuse include:
- Ear of Dionysius, experience the unique acoustics of this limestone cave
- Aretusa Fountain, admire the legendary freshwater spring surrounded by papyrus plants
- Explore the vibrant local markets, where you can taste and purchase fresh Sicilian produce
- Take a boat tour around Ortigia Island, offering a unique perspective of the city from the water
- Enjoy a traditional Sicilian cooking class, learning to make local dishes with fresh ingredients.
Whether you can cancel your bus ticket from Rome to Syracuse depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company FlixBus, Itabus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rome to Syracuse.
Yes, the following luggage options are included when booking a bus ticket from Rome to Syracuse:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Rome to Syracuse:
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
Yes, you can bring your pet on the bus from Rome to Syracuse. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Rome to Syracuse with the following bus company: FlixBus, Itabus
Yes, there are USB plugs on board the bus from Rome to Syracuse with the following bus company: FlixBus, Itabus.
Yes, there is Wifi on board the bus from Rome to Syracuse with the following bus company: FlixBus, Itabus.
Since both Rome and Syracuse are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the train as it is the most popular way to get from Rome to Syracuse among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Syracuse, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas and during events. It's advisable to avoid poorly lit or isolated neighborhoods at night. Common scams include overcharging by unlicensed taxi drivers and fraudulent ticket sellers near popular attractions. Staying alert and using official transportation and ticket services can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Rome to Syracuse
Most Rome to Syracuse buses use the Roma, Autostazione Tiburtina to Syracuse, Corso Umberto I station pair. Use this guide to compare Rome and Syracuse bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Rome
Arrival bus stations in Syracuse
Which Rome station do buses to Syracuse leave from?
Buses from Rome to Syracuse leave from Roma, Autostazione Tiburtina. The station is 2 miles (4 km) from Rome city centre at Largo Guido Mazzoni, snc, 00162 Roma RM, Italy.
Roma, Autostazione TiburtinaLargo Guido Mazzoni, snc, 00162 Roma RM, Italy
City-centre transport
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Bus490, 495 · 16m · €2 · every ~22 min
SubwayMeb · 7m · €2 · every ~15 min
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Roma, Autostazione (Metro Anagnina)Rome Anagnina, Via Tuscolana, 173
City-centre transport
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
BusRome Fiumicino, Scario · 31m · €1
nMA · 38m · €2 · every ~4 min
SubwayMea · 24m · €2 · every ~29 min
Shuttle31m · €10
More options for your journey from Rome to Syracuse
Here are some other resources that might have the information you need
Most popular buses to and from Syracuse and Rome
Most popular bus connections to Syracuse
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