The cheapest and fastest buses from Syracuse to Brindisi
Cheapest price
$110
Average price
$110
Fastest journey
14 h 30 m
Average duration
14 h 30 m
Buses per day
1
Distance
456 km
The best way to find a cheap bus ticket from Syracuse to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse to Brindisi will cost around $110 if you buy it on the day, but the cheapest tickets can be found for only $110.
Of the 1 buses that leave Syracuse for Brindisi on Wed, Feb 04, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Feb 04 the direct buses cover the 456 km distance in an average of 14 h 30 m but if you time it right, some buses will get you there in just 14 h 30 m .
On Wed, Feb 04 the slowest buses will take 14 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and train for Syracuse to Brindisi
Omio recommends booking the train as it is the most popular option from Syracuse to Brindisi among Omio's users. If you are prioritising price take the train with prices starting from €27. For those with little time consider booking a train which can get you there in 9h 38m. The ticket price range depends on the travel mode: a train costs an average of €27, and a bus costs an average of €29.
Distance: 283 miles (456 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€59 Average price | €55 Average price Cheapest |
13h 55m Average total duration 13h 25m Onboard + 30m Additional time* | 10h 8m Average total duration Fastest 9h 38m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Syracuse to Brindisi bus times
The table below shows live departures for Syracuse to Brindisi buses for today, Tuesday, February 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:05 PM Syracuse | 12h55 | 4:00 AM Brindisi | 0 transfersDirect | |
| Wednesday, February 4 | |||||
![]() | 5:15 AM Syracuse | 14h30 | 7:45 PM Brindisi | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse to Brindisi by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 04
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Journey information
Overview: Bus from Syracuse to Brindisi
Buses from Syracuse to Brindisi run on average 2 times per day, taking around 13h 25m. Cheap bus tickets for this journey start at $37 (€29) but you can travel from only $34 (€27) by train.
The earliest bus runs at 06:15, the last at 22:40. The fastest bus covers the 283 miles (456 km) distance in 12h 55m.
Distance 283 miles (456 km) |
Average bus duration 13h 25m |
Cheapest ticket price $37 (€29) |
Buses per day 2 |
Fastest bus 12h 55m |
First bus 06:15 |
Last bus 22:40 |
FAQs: Bus from Syracuse to Brindisi
Find answers to the most common questions about traveling from Syracuse to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Syracuse to Brindisi
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