Travel Information
Compare bus and train for Syracuse to Brindisi
Omio recommends booking the train as it is the most popular option from Syracuse to Brindisi among Omio's users. If you are prioritising price take the train with prices starting from €27. For those with little time consider booking a train which can get you there in 9h 38m. The ticket price range depends on the travel mode: a train costs an average of €27, and a bus costs an average of €29.
Distance: 283 miles (456 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€59 Average price | €55 Average price Cheapest |
13h 55m Average total duration 13h 25m Onboard + 30m Additional time* | 10h 8m Average total duration Fastest 9h 38m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Syracuse to Brindisi bus times
The table below shows live departures for Syracuse to Brindisi buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:05 PM Syracuse | 12h55 | 4:00 AM Brindisi | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse to Brindisi by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
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Dec 27
Journey information
Overview: Bus from Syracuse to Brindisi
Buses from Syracuse to Brindisi run on average 2 times per day, taking around 13h 25m. Cheap bus tickets for this journey start at $37 (€29) but you can travel from only $33 (€27) by train.
The earliest bus runs at 06:15, the last at 22:40. The fastest bus covers the 283 miles (456 km) distance in 12h 55m.
Distance 283 miles (456 km) |
Average bus duration 13h 25m |
Cheapest ticket price $37 (€29) |
Buses per day 2 |
Fastest bus 12h 55m |
First bus 06:15 |
Last bus 22:40 |
FAQs: Bus from Syracuse to Brindisi
Find answers to the most common questions about traveling from Syracuse to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Syracuse to Brindisi, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Syracuse to Brindisi
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