- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price on Oct 10
$277
Average ticket price on Oct 10
$332
Fastest journey on Oct 10
1 d 6 h 5 m
Average journey duration on Oct 10
1 d 10 h 16 m
Buses on Oct 10
8
Distance
1363 km
The best way to find a cheap bus ticket from Madrid to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Rome will cost around $332 if you buy it on the day, but the cheapest tickets can be found for only $277.
It's difficult to get from Madrid to Rome without transferring at least once.
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FlixBus · FlixBusBuses from Madrid to Rome run on average 7 times per day, taking around 32h 48m. Cheap bus tickets for this journey start at $64 (€53) but you can travel from only $29 (€24) by flight.
The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 846 miles (1363 km) distance in 26h 35m.
Distance 846 miles (1363 km) |
Average bus duration 32h 48m |
Cheapest ticket price $64 (€53) |
Buses per day 7 |
Fastest bus 26h 35m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 70 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:05PM | Arrival Time 06:05AM | Duration 35h00 | Departure days Everyday | Cheapest price $202 |
Operator FlixBus | Departure Time 08:50PM | Arrival Time 07:00AM | Duration 34h10 | Departure days Everyday | Cheapest price $209 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 09:10PM | Duration 46h15 | Departure days Mon, Tue | Cheapest price $262 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 05:35AM | Duration 54h35 | Departure days Mon | Cheapest price $259 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 12:15PM | Duration 36h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $193 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 12:15PM | Duration 36h16 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $211 |
The table below shows live departures for Madrid to Rome buses for today, Friday, October 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:35 PM Madrid, Estación Sur de Autobuses | 36h40 | 12:15 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 11:35 PM Madrid, Estación Sur de Autobuses | 36h15 | 11:50 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 11:59 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 35h51 | 11:50 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 11:59 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 36h16 | 12:15 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
| Saturday, October 10 | |||||
FlixBus · FlixBus | 7:05 PM Madrid, Estación Sur de Autobuses | 35h00 | 6:05 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:05 PM Madrid, Estación Sur de Autobuses | 30h05 | 1:10 AM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:50 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 36h25 | 9:15 AM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:50 PM Madrid, Estación Sur de Autobuses | 34h10 | 7:00 AM Roma, Autostazione Tiburtina | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Find answers to the most common questions about traveling from Madrid to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Madrid to Rome buses use the Madrid, Estación Sur de Autobuses to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Madrid and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower, and Ticket Office.
Food options include: Rodilla, Mahoudrid
ATMs are aTMs located throughout T4, major cards accepted .
Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).
Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.
Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
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