- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
The best way to find a cheap bus ticket from Lyon to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Rome will cost around $87 if you buy it on the day, but the cheapest tickets can be found for only $39.
On Sat, Nov 14, we found 15 buses from Lyon to Rome, including 4 direct services.
On Sat, Nov 14 the direct buses cover the 747 km distance in an average of 14 h 40 m but if you time it right, some buses will get you there in just 13 h 40 m .
On Sat, Nov 14 the slowest buses will take 15 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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Buses from Lyon to Rome run on average 14 times per day, taking around 14h 51m. Cheap bus tickets for this journey start at $30 (€25) but you can travel from only $24 (€20) by train.
There are 5 buses per day. The earliest bus runs at 00:04, the last at 23:50. The fastest bus covers the 464 miles (747 km) distance in 12h 50m.
Distance 464 miles (747 km) |
Average bus duration 14h 51m |
Cheapest ticket price $30 (€25) |
Buses per day 14 |
Direct buses 5 |
Fastest bus 12h 50m |
First bus 12:04 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 35 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Lyon to Rome.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 06:05PM | Duration 16h35 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $60 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 06:05PM | Duration 14h50 | Departure days Sun | Cheapest price $98 |
Operator Itabus | Departure Time 03:15AM | Arrival Time 07:15PM | Duration 16h00 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $30 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 11:40PM | Duration 17h25 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $68 |
Operator FlixBus | Departure Time 08:05AM | Arrival Time 01:10AM | Duration 17h05 | Departure days Thu | Cheapest price $110 |
Operator Itabus | Departure Time 08:20AM | Arrival Time 11:45PM | Duration 15h25 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $36 |
Operator FlixBus | Departure Time 09:35AM | Arrival Time 11:45PM | Duration 14h10 | Departure days Mon, Tue, Sat, Sun | Cheapest price $64 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 05:35AM | Duration 18h50 | Departure days Wed | Cheapest price $82 |
Operator FlixBus | Departure Time 10:50AM | Arrival Time 06:10AM | Duration 19h20 | Departure days Wed, Thu | Cheapest price $80 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 06:10AM | Duration 17h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $87 |
Operator FlixBus | Departure Time 02:55PM | Arrival Time 07:40AM | Duration 16h45 | Departure days Everyday | Cheapest price $70 |
Operator Itabus | Departure Time 03:30PM | Arrival Time 07:00AM | Duration 15h30 | Departure days Everyday | Cheapest price $71 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 10:00AM | Duration 16h00 | Departure days Everyday | Cheapest price $70 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 11:50AM | Duration 16h55 | Departure days Mon, Fri, Sat, Sun | Cheapest price $81 |
Operator FlixBus | Departure Time 08:45PM | Arrival Time 12:15PM | Duration 15h30 | Departure days Mon, Thu, Sat, Sun | Cheapest price $63 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 02:45PM | Duration 15h45 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $68 |
The table below shows live departures for Lyon to Rome buses for today, Friday, November 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h30 | 2:30 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 11:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h05 | 3:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
| Saturday, November 14 | |||||
FlixBus · FlixBus | 1:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h20 | 5:50 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 1:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h35 | 4:05 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3097 · 2125 | 3:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h00 | 7:15 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 6:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h10 | 11:25 PM Roma, Autostazione Tiburtina | 1 transfer | |
2899 · 1423 | 8:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h25 | 11:45 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 9:35 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h10 | 11:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 12:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h20 | 6:05 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 12:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h50 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 2:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h05 | 7:00 AM Roma, Autostazione Tiburtina | 1 transfer | |
3897 | 3:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h30 | 7:00 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 6:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 13h40 | 7:40 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 6:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h55 | 11:50 AM Roma, Autostazione Tiburtina | 1 transfer | |
This is the last bus of the day. | |||||
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Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Rome.
Find answers to the most common questions about traveling from Lyon to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Lyon to Rome buses use the Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Lyon and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Roma is 1 km from Rome city centre. Public transport options include:
Roma has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast-food options and a cafe.
Free public WiFi available in waiting areas. ATMs are aTMs located at entrance area.
Ticket office support is available at Roma.
Available at Roma: Parking, Taxis, WC.
Accessibility facilities are available at Roma: Wheelchair accessible entrances and restrooms.
Check bus stations information for Lyon and Rome, including where buses depart and arrive on this route.
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