- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price
$74
Average price
$115
Fastest journey
13 h 40 m
Average duration
14 h 24 m
Buses per day
16
Distance
747 km
The best way to find a cheap bus ticket from Lyon to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Rome will cost around $115 if you buy it on the day, but the cheapest tickets can be found for only $74.
Of the 16 buses that leave Lyon for Rome on Sun, Aug 16, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Aug 16 the direct buses cover the 747 km distance in an average of 14 h 24 m but if you time it right, some buses will get you there in just 13 h 40 m .
On Sun, Aug 16 the slowest buses will take 14 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3491
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
3491
4787
FlixBusOmio recommends booking the bus as it is the most popular option from Lyon to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $31. For those with little time consider booking a flight which can get you there in 5h 22m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of $31, and a train costs an average of $119.
Distance: 464 miles (747 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$65 Average price Cheapest | $214 Average price | $225 Average price | $373 Average price (fuel + tolls) |
12h 34m Average total duration 12h 4m Onboard + 30m Additional time* | 8h 22m Average total duration Fastest 5h 22m Onboard + 3h 0m Additional time* | 10h 11m Average total duration 9h 41m Onboard + 30m Additional time* | 10h 36m Average total duration (door-to-door) |
0.7 - 1.9kg CO2 emissions Lowest | 2.2 - 4.5kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lyon to Rome:
A bus is $149 less than a flight for this route with tickets for a flight from Lyon to Rome costing on average $214.
A bus is $160 less than a train for this route with tickets for a train from Lyon to Rome costing on average $225.
Other travel options to Rome take longer:
Train takes on average 9h 41m.
Bus takes on average 12h 4m.
Tickets start at around $65 compared to roughly $373 in fuel and tolls — a saving of about $308. The journey takes 12h 4m versus 10h 36m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Itabus, FlixBus, BlaBlaCar Bus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:15AM | Arrival Time 04:05PM | Duration 14h50 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 06:05PM | Duration 14h50 | Departure days Sat, Sun | Cheapest price $99 |
Operator BlaBlaCar Bus | Departure Time 05:35AM | Arrival Time 08:15PM | Duration 14h40 | Departure days Everyday | Cheapest price $86 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 11:25PM | Duration 17h10 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $83 |
Operator FlixBus | Departure Time 08:05AM | Arrival Time 11:25PM | Duration 15h20 | Departure days Sun | Cheapest price $99 |
Operator Itabus | Departure Time 09:15AM | Arrival Time 11:45PM | Duration 14h30 | Departure days Everyday | Cheapest price $62 |
Operator FlixBus | Departure Time 09:35AM | Arrival Time 11:45PM | Duration 14h10 | Departure days Mon, Tue, Fri, Sat | Cheapest price $95 |
Operator FlixBus | Departure Time 10:50AM | Arrival Time 01:10AM | Duration 14h20 | Departure days Wed, Thu, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 05:35AM | Duration 16h50 | Departure days Everyday | Cheapest price $110 |
Operator FlixBus | Departure Time 02:55PM | Arrival Time 07:00AM | Duration 16h05 | Departure days Everyday | Cheapest price $80 |
Operator Itabus | Departure Time 03:30PM | Arrival Time 07:00AM | Duration 15h30 | Departure days Everyday | Cheapest price $90 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 07:40AM | Duration 15h40 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $81 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 10:15AM | Duration 16h15 | Departure days Everyday | Cheapest price $87 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 11:50AM | Duration 16h55 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $111 |
Operator FlixBus | Departure Time 08:45PM | Arrival Time 01:20PM | Duration 16h35 | Departure days Everyday | Cheapest price $83 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 02:30PM | Duration 15h30 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $87 |
The table below shows live departures for Lyon to Rome buses for today, Saturday, August 15. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 6:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 13h40 | 7:40 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 6:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h55 | 11:50 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 8:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h35 | 1:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 8:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h30 | 12:15 PM Roma, Autostazione (Metro Anagnina) | 0 transfersDirect | |
FlixBus · FlixBus | 11:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h30 | 2:30 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 1:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h50 | 4:05 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 1:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h35 | 5:50 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 3:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h50 | 6:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
4787 | 5:35 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h40 | 8:15 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 8:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h20 | 11:25 PM Roma, Autostazione Tiburtina | 1 transfer | |
3491 | 9:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h30 | 11:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 10:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h20 | 1:10 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 12:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h20 | 6:05 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 12:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h50 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 2:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h05 | 7:00 AM Roma, Autostazione Tiburtina | 1 transfer | |
3897 | 3:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h30 | 7:00 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lyon to Rome run on average 12 times per day, taking around 12h 4m. Cheap bus tickets for this journey start at $31 if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:04, the last at 23:50. The fastest bus covers the 464 miles (747 km) distance in 14h 10m.
Distance 464 miles (747 km) |
Average bus duration 12h 4m |
Cheapest ticket price $31 |
Buses per day 12 |
Direct buses 5 |
Fastest bus 14h 10m |
First bus 12:04 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 42 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Find answers to the most common questions about traveling from Lyon to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Lyon to Rome buses use the Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Lyon and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, Gare Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Bistro Lyonnais (0.2 km), Fast Food Express (0.3 km).
Free Wi-Fi. ATMs are located near the main entrance and in the shopping area.
Ticket office support is available at Lyon, Gare Perrache.
Available at Lyon, Gare Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Perrache: Elevators, ramps.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Roma is 1 km from Rome city centre. Public transport options include:
Roma has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast-food options and a cafe.
Free public WiFi available in waiting areas. ATMs are aTMs located at entrance area.
Ticket office support is available at Roma.
Available at Roma: Parking, Taxis, WC.
Accessibility facilities are available at Roma: Wheelchair accessible entrances and restrooms.
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