Are there accessibility options when taking a bus from Prague to Rome?

Yes, the following accessibility options are available when taking the bus from Prague to Rome: FlixBus Assistance Priority boarding Wheelchair-accessible buses.

What are the best sights in Rome?

Some of the most interesting sights to explore in Rome are: Colosseum, an ancient amphitheater known for its gladiatorial contests and iconic architecture Vatican Museums, a vast collection of art and historical artifacts including the Sistine Chapel Roman Forum, the ruins of ancient Rome's center for public life and government Pantheon, a well-preserved Roman temple with a striking dome and oculus Trevi Fountain, a famous Baroque fountain where visitors traditionally toss coins for good luck.

What are the best things to do in Rome?

The best things to do in Rome include: Explore Trastevere, a charming neighborhood with narrow streets and vibrant nightlife Take a stroll through Villa Borghese, a beautiful park with museums and gardens Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists Visit the Spanish Steps, a popular spot for people-watching and enjoying the view Discover the Catacombs, ancient underground burial sites with guided tours.

Is luggage included in the bus ticket price from Prague to Rome?

Yes, the following luggage options are included when booking a bus ticket from Prague to Rome: FlixBus One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).

Can I bring my pet on board the bus from Prague to Rome?

Yes, you can bring your pet on the bus from Prague to Rome. The following conditions apply: FlixBus Small pets in carriers allowed guide dogs travel for free.

PRAGUE to ROME bus from $28 (€23) with FlixBus

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The cheapest and fastest buses from Prague to Rome

Showing times and prices for Jul 12

Cheapest price

$170

Average price

$211

Fastest journey

19 h 15 m

Average duration

19 h 38 m

Buses per day

Distance

923 km

Cheap tickets

The best way to find a cheap bus ticket from Prague to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Prague to Rome will cost around $211 if you buy it on the day, but the cheapest tickets can be found for only $170.

Fast buses

Of the 41 buses that leave Prague for Rome on Sun, Jul 12, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sun, Jul 12 the direct buses cover the 923 km distance in an average of 19 h 38 m but if you time it right, some buses will get you there in just 19 h 15 m .

On Sun, Jul 12 the slowest buses will take 20 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
5:30 PM21h15
Praha, ÚAN Florenc
2:45 PMRoma, Autostazione Tiburtina
$1701One-way
0 transfers
FlixBus
5:45 PM21h00
Prague, Central Train Station
2:45 PMRoma, Autostazione Tiburtina
$1701One-way
0 transfers
FlixBus · FlixBus
9:25 PM20h25
Praha, ÚAN Florenc
5:50 PMRoma, Autostazione (Metro Anagnina)
$1721One-way
1 transfer
FlixBus · FlixBus · FlixBus
12:55 PM24h25
Praha, Zličín
1:20 PMRoma, Autostazione Tiburtina
$1741One-way
2 transfers
FlixBus · FlixBus
5:45 PM19h35
Praha, Na Knížecí
1:20 PMRoma, Autostazione Tiburtina
$1741One-way
1 transfer

Travel Information

Compare bus and flight for Prague to Rome

Omio recommends booking the flight as it is the most popular option from Prague to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a flight which can get you there in 3h 35m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of $68, and a flight costs an average of $28.

Distance: 573 miles (923 km)

Compare bus with

Bus	Most popular Flight	Driving
$119 Average price Cheapest	$192 Average price	$351 Average price (fuel + tolls)
15h 10m Average total duration 14h 40m Onboard + 30m Additional time*	6h 35m Average total duration Fastest 3h 35m Onboard + 3h 0m Additional time*	14h 14m Average total duration (door-to-door)
0.9 - 2.3kg CO2 emissions Lowest	2.8 - 5.5kg CO2 emissions	- CO2 emissions
Most popular bus company	Most popular airline	Your own car or car rental
Direct Options	Direct Options	Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Prague to Rome is a bus with an average price of $119 (€98).

This is compared to other travel options from Prague to Rome:

A bus is $74 (€61) less than a flight for this route with tickets for a flight from Prague to Rome costing on average $192 (€158).

The fastest way to travel from Prague to Rome is by flight with an average journey time of 3h 35m.

Other travel options to Rome take longer:

Bus takes on average 14h 40m.

Train takes on average 19h 38m.

It's helpful to compare your options as there are 2 ways to travel between Prague and Rome including taking a bus and flight.

We recommend using the flight as it is the most popular way to get from Prague to Rome among Omio's users.

Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $119 (€98) compared to roughly $351 (€289) in fuel and tolls — a saving of about $232 (€191). The journey takes 14h 40m versus 14h 14m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Direct services are operated by FlixBus.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Prague to Rome Bus Timetables

Operator	Departure Time	Arrival Time	Duration	Departure days	Cheapest price
Operator FlixBus	Departure Time 02:30AM	Arrival Time 11:00PM	Duration 20h30	Departure days Mon, Tue, Wed, Thu, Fri, Sun	Cheapest price $135
Operator FlixBus	Departure Time 05:50AM	Arrival Time 09:30AM	Duration 27h40	Departure days Mon, Tue, Wed, Thu, Fri, Sun	Cheapest price $157
Operator FlixBus	Departure Time 06:20AM	Arrival Time 06:10AM	Duration 23h50	Departure days Mon, Tue, Wed, Thu, Fri, Sun	Cheapest price $135
Operator FlixBus	Departure Time 07:00AM	Arrival Time 06:10AM	Duration 23h10	Departure days Mon, Tue, Fri, Sun	Cheapest price $159
Operator FlixBus	Departure Time 07:55AM	Arrival Time 07:05AM	Duration 23h10	Departure days Mon, Thu, Fri	Cheapest price $168
Operator FlixBus	Departure Time 08:20AM	Arrival Time 09:30AM	Duration 25h10	Departure days Sun	Cheapest price $227
Operator FlixBus	Departure Time 08:30AM	Arrival Time 09:30AM	Duration 25h00	Departure days Mon, Tue, Wed, Thu, Fri, Sun	Cheapest price $127
Operator FlixBus	Departure Time 09:00AM	Arrival Time 06:10AM	Duration 21h10	Departure days Mon, Tue, Wed, Thu, Fri, Sun	Cheapest price $136
Operator FlixBus	Departure Time 09:10AM	Arrival Time 07:05AM	Duration 21h55	Departure days Sun	Cheapest price $232
Operator FlixBus	Departure Time 09:40AM	Arrival Time 12:15PM	Duration 26h35	Departure days Mon, Tue, Wed, Thu, Fri, Sun	Cheapest price $157
Operator FlixBus	Departure Time 09:50AM	Arrival Time 09:20AM	Duration 23h30	Departure days Tue, Wed	Cheapest price $151
Operator FlixBus	Departure Time 10:05AM	Arrival Time 09:20AM	Duration 23h15	Departure days Tue, Wed	Cheapest price $151
Operator FlixBus	Departure Time 10:55AM	Arrival Time 09:30AM	Duration 22h35	Departure days Mon, Tue, Wed, Thu, Sun	Cheapest price $130
Operator FlixBus	Departure Time 11:00AM	Arrival Time 07:05AM	Duration 20h05	Departure days Mon, Wed, Thu, Fri, Sun	Cheapest price $142
Operator FlixBus	Departure Time 11:15AM	Arrival Time 07:05AM	Duration 19h50	Departure days Mon, Thu, Fri, Sun	Cheapest price $156
Operator FlixBus	Departure Time 12:50PM	Arrival Time 12:15PM	Duration 23h25	Departure days Mon, Tue, Wed, Thu, Fri, Sun	Cheapest price $131
Operator FlixBus	Departure Time 12:55PM	Arrival Time 01:20PM	Duration 24h25	Departure days Sun	Cheapest price $174
Operator FlixBus	Departure Time 01:05PM	Arrival Time 01:20PM	Duration 24h15	Departure days Mon, Tue, Wed, Thu, Fri	Cheapest price $131
Operator FlixBus	Departure Time 02:00PM	Arrival Time 09:30AM	Duration 19h30	Departure days Sun	Cheapest price $190
Operator FlixBus	Departure Time 02:15PM	Arrival Time 09:30AM	Duration 19h15	Departure days Sun	Cheapest price $192
Operator FlixBus	Departure Time 02:30PM	Arrival Time 01:20PM	Duration 22h50	Departure days Mon, Tue, Wed, Thu, Fri, Sun	Cheapest price $149
Operator FlixBus	Departure Time 03:00PM	Arrival Time 02:45PM	Duration 23h45	Departure days Mon, Tue, Fri, Sun	Cheapest price $148
Operator FlixBus	Departure Time 03:05PM	Arrival Time 01:20PM	Duration 22h15	Departure days Mon, Tue, Wed, Thu	Cheapest price $155
Operator FlixBus	Departure Time 03:30PM	Arrival Time 02:45PM	Duration 23h15	Departure days Mon, Tue, Fri, Sun	Cheapest price $148
Operator FlixBus	Departure Time 04:00PM	Arrival Time 12:15PM	Duration 20h15	Departure days Mon, Tue, Wed, Thu, Sun	Cheapest price $131
Operator FlixBus	Departure Time 04:15PM	Arrival Time 12:15PM	Duration 20h00	Departure days Mon, Tue, Wed, Thu, Sat, Sun	Cheapest price $131
Operator FlixBus	Departure Time 05:15PM	Arrival Time 03:05PM	Duration 21h50	Departure days Everyday	Cheapest price $147
Operator FlixBus	Departure Time 05:30PM	Arrival Time 03:05PM	Duration 21h35	Departure days Everyday	Cheapest price $108
Operator FlixBus	Departure Time 05:45PM	Arrival Time 01:20PM	Duration 19h35	Departure days Everyday	Cheapest price $108
Operator RegioJet a.s.	Departure Time 06:30PM	Arrival Time 02:45PM	Duration 20h15	Departure days Mon, Fri	Cheapest price $87
Operator FlixBus	Departure Time 06:45PM	Arrival Time 05:25PM	Duration 22h40	Departure days Everyday	Cheapest price $127
Operator FlixBus	Departure Time 06:55PM	Arrival Time 06:45PM	Duration 23h50	Departure days Fri	Cheapest price $177
Operator FlixBus	Departure Time 07:25PM	Arrival Time 06:45PM	Duration 23h20	Departure days Mon, Tue, Wed, Thu, Sat	Cheapest price $167
Operator FlixBus	Departure Time 08:20PM	Arrival Time 05:50PM	Duration 21h30	Departure days Sat, Sun	Cheapest price $209
Operator FlixBus	Departure Time 08:25PM	Arrival Time 06:45PM	Duration 22h20	Departure days Sun	Cheapest price $214
Operator FlixBus	Departure Time 09:25PM	Arrival Time 05:25PM	Duration 20h00	Departure days Everyday	Cheapest price $128
Operator FlixBus	Departure Time 09:50PM	Arrival Time 11:00PM	Duration 25h10	Departure days Everyday	Cheapest price $133
Operator FlixBus	Departure Time 09:55PM	Arrival Time 08:35PM	Duration 22h40	Departure days Everyday	Cheapest price $150
Operator FlixBus	Departure Time 10:25PM	Arrival Time 11:00PM	Duration 24h35	Departure days Everyday	Cheapest price $133
Operator FlixBus	Departure Time 11:40PM	Arrival Time 11:00PM	Duration 23h20	Departure days Mon, Tue, Wed, Thu, Fri, Sun	Cheapest price $131
Operator FlixBus	Departure Time 11:50PM	Arrival Time 09:25PM	Duration 21h35	Departure days Everyday	Cheapest price $154

Live departures

Prague to Rome bus times

The table below shows live departures for Prague to Rome buses for today, Saturday, July 11. You can also manually refresh the results below to see updated bus journeys.

Last updated at

Provider	Departs	Duration	Arrives	Transfers
FlixBus · FlixBus · FlixBus	8:20 PM Prague, Central Train Station	21h30	5:50 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus · FlixBus	9:25 PM Praha, ÚAN Florenc	20h00	5:25 PM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus	9:25 PM Praha, ÚAN Florenc	20h25	5:50 PM Roma, Autostazione (Metro Anagnina)	1 transfer
FlixBus · FlixBus · FlixBus	9:50 PM Praha, Na Knížecí	25h10	11:00 PM Roma, Autostazione Tiburtina	2 transfers
FlixBus · FlixBus	9:55 PM Praha, ÚAN Florenc	22h40	8:35 PM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus · FlixBus	10:25 PM Praha, M. Horákové (Hradčanská)	24h35	11:00 PM Roma, Autostazione Tiburtina	2 transfers
FlixBus · FlixBus · FlixBus	11:50 PM Prague, Central Train Station	21h35	9:25 PM Roma, Autostazione Tiburtina	2 transfers
Sunday, July 12
FlixBus · FlixBus	2:30 AM Prague, Central Train Station	20h30	11:00 PM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus · FlixBus	5:50 AM Prague, Central Train Station	27h40	9:30 AM Roma, Autostazione Tiburtina	2 transfers
FlixBus · FlixBus	6:20 AM Praha, Černý Most	23h50	6:10 AM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus	7:00 AM Praha, ÚAN Florenc	23h10	6:10 AM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus · FlixBus	8:20 AM Praha, Černý Most	25h10	9:30 AM Roma, Autostazione Tiburtina	2 transfers
FlixBus · FlixBus · FlixBus	8:30 AM Praha, Roztyly	25h00	9:30 AM Roma, Autostazione Tiburtina	2 transfers
FlixBus · FlixBus · FlixBus	9:00 AM Prague, Central Train Station	21h10	6:10 AM Roma, Autostazione Tiburtina	2 transfers
FlixBus · FlixBus · FlixBus	9:10 AM Praha, Na Knížecí	21h55	7:05 AM Roma, Autostazione Tiburtina	2 transfers
FlixBus · FlixBus · FlixBus	9:40 AM Praha, Na Knížecí	26h35	12:15 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus · FlixBus · FlixBus	10:55 AM Praha, Na Knížecí	22h35	9:30 AM Roma, Autostazione Tiburtina	2 transfers
FlixBus · FlixBus	11:00 AM Praha, ÚAN Florenc	20h05	7:05 AM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus	11:15 AM Prague, Central Train Station	19h50	7:05 AM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus · FlixBus	12:50 PM Praha, M. Horákové (Hradčanská)	26h15	3:05 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus · FlixBus	12:50 PM Praha, M. Horákové (Hradčanská)	24h30	1:20 PM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus · FlixBus	12:55 PM Praha, Zličín	24h25	1:20 PM Roma, Autostazione Tiburtina	2 transfers
FlixBus · FlixBus	2:00 PM Praha, ÚAN Florenc	19h30	9:30 AM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus	2:15 PM Prague, Central Train Station	19h15	9:30 AM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus	2:30 PM Praha, Černý Most	22h50	1:20 PM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus · FlixBus	2:30 PM Praha, Černý Most	24h35	3:05 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus · FlixBus · FlixBus	3:00 PM Praha, Černý Most	26h50	5:50 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus · FlixBus	3:00 PM Praha, Černý Most	23h45	2:45 PM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus	3:30 PM Praha, Roztyly	23h15	2:45 PM Roma, Autostazione Tiburtina	1 transfer
FlixBus · FlixBus · FlixBus	3:30 PM Praha, Roztyly	26h20	5:50 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus · FlixBus · FlixBus	4:00 PM Praha, ÚAN Florenc	20h15	12:15 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus · FlixBus · FlixBus	4:15 PM Prague, Central Train Station	20h00	12:15 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus · FlixBus · FlixBus	5:15 PM Praha, ÚAN Florenc	21h50	3:05 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus	5:30 PM Praha, ÚAN Florenc	21h15	2:45 PM Roma, Autostazione Tiburtina	0 transfersDirect
FlixBus · FlixBus · FlixBus	5:30 PM Prague, Central Train Station	21h35	3:05 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus · FlixBus	5:45 PM Praha, Na Knížecí	19h35	1:20 PM Roma, Autostazione Tiburtina	1 transfer
FlixBus	5:45 PM Prague, Central Train Station	21h00	2:45 PM Roma, Autostazione Tiburtina	0 transfersDirect
FlixBus · FlixBus · FlixBus	5:45 PM Praha, Na Knížecí	21h20	3:05 PM Roma, Autostazione (Metro Anagnina)	2 transfers
FlixBus · FlixBus	6:45 PM Praha, Roztyly	22h40	5:25 PM Roma, Autostazione Tiburtina	1 transfer
This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Prague to Rome by bus or flight

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Why should you book Prague to Rome buses with Omio?

FlixBus operates all buses services from Prague to Rome.

Omio is an official ticket reseller for all your travel options from Prague to Rome.

Why book with Omio vs FlixBus?

Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Prague to Rome.

Why book with Omio over Wanderu or Trainline?

Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Prague to Rome.

Journey information

Overview: Bus from Prague to Rome

Czechia

Italy

Buses from Prague to Rome run on average 38 times per day, taking around 14h 40m. Cheap bus tickets for this journey start at $68 (€56) but you can travel from only $28 (€23) by flight.

There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 573 miles (923 km) distance in 19h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.

Price information

Cheapest alternative travel mode

Flight from $28 (€23)

Distance

573 miles (923 km)

Average bus duration

14h 40m

Cheapest ticket price

$68 (€56)

Buses per day

Direct buses

Fastest bus

19h 15m

First bus

12:10 AM

Last bus

11:50 PM

Cheapest Month

Mar

Cheapest Day

Mon

High Season

Jul - Sep

Low Season

Jan - Mar

Busiest Day

Tue

Least Busy Day

Sun

Best time to book

42 days

Price information

Cheapest alternative travel mode

Flight from $28 (€23)

Bus providers: FlixBus from Prague to RomeYou can travel by bus between Prague to Rome with FlixBus for as low as $28 (€23). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About

FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.

Luggage & cancellation policy

Average Duration

19h 15m

Cheapest Price

$90 (€74)

FlixBus frequency

39 a day

Luggage included

One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).

Additional luggage

Additional luggage can be purchased for a fee.

Cancellation Policy

You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

Amenities on board the bus

Wifi

Food sold onboard

Seat reservation

Toilets

USB plugs

Accessibility

Assistance; Priority boarding; Wheelchair-accessible buses.

Bikes

Bikes are allowed for a fee; must be booked.

Pets

Small pets in carriers allowed; guide dogs travel for free.

Learn more about FlixBus

Complete guide to Rome

Things to do in Rome

Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.

Must visit

Vatican Museums

One of the world's great museum complexes, home to vast papal collections and the Sistine Chapel. A priority visit for art, history, and Renaissance masterpieces.

View on map Visit website

Must visit

Galleria Borghese

A superb villa museum with Bernini sculptures and major paintings by Caravaggio, Raphael, and Titian. Timed entry is essential due to limited capacity.

View on map Visit website

Recommended

Capitoline Museums

The city's historic civic museums on Capitoline Hill, known for classical sculpture, ancient Roman art, and excellent views over the Forum.

View on map Visit website

Euro

Moderate for Western Europe. Sights and central hotels cost more, but food, coffee, and transit can be good value.

Average meal costs

Budget: EUR 8-15 for pizza, panini, or takeaway.
Mid-range: EUR 20-40 per person at a casual restaurant.
Fine dining: EUR 80+ per person at upscale restaurants.
Coffee: EUR 1.20-2.50 for espresso or cappuccino.

Tipping culture

Service is often included or modest. Locals may round up or leave EUR 1-2 at cafes; 5-10% is appreciated at restaurants for good service, not obligatory. Round up taxis.

FAQs: Bus from Prague to Rome

Find answers to the most common questions about traveling from Prague to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Cheap bus tickets from Prague to Rome can start from as little as $68 (€56) when you book in advance. The average bus ticket price for Prague to Rome is $119 (€98) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.

The average journey time by bus from Prague to Rome is 19h 15m to travel the 573 miles (923 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.

The earliest bus from Prague to Rome leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.

The latest bus from Prague to Rome leaves at 11:50 PM.

Yes, there are 2 direct buses a day from Prague to Rome with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.

When taking a bus from Prague to Rome, you can count on FlixBus for the best way to get you to Rome. You can also check all possible bus companies who offer a service between Prague and Rome and compare the amenities they offer before buying a bus ticket.

A trip to Rome from Prague is worth doing but not as a day trip with a journey time of 19h 15m each way. Check with Omio app the best way to travel.

The cheapest month for a bus from Prague to Rome is March.

It's helpful to compare your options as there are 2 ways to travel between Prague and Rome including taking a bus and flight.

Yes, the following accessibility options are available when taking the bus from Prague to Rome:

FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.

Yes, there are bathrooms on board the bus from Prague to Rome for bus company FlixBus.

Some of the most interesting sights to explore in Rome are:

Colosseum, an ancient amphitheater known for its gladiatorial contests and iconic architecture
Vatican Museums, a vast collection of art and historical artifacts including the Sistine Chapel
Roman Forum, the ruins of ancient Rome's center for public life and government
Pantheon, a well-preserved Roman temple with a striking dome and oculus
Trevi Fountain, a famous Baroque fountain where visitors traditionally toss coins for good luck.

The best things to do in Rome include:

Explore Trastevere, a charming neighborhood with narrow streets and vibrant nightlife
Take a stroll through Villa Borghese, a beautiful park with museums and gardens
Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists
Visit the Spanish Steps, a popular spot for people-watching and enjoying the view
Discover the Catacombs, ancient underground burial sites with guided tours.

Whether you can cancel your bus ticket from Prague to Rome depends on the bus companies:

FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

Yes, bikes are allowed on board the bus with bus company FlixBus.

Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.

Yes, there is food available to purchase on board the bus from Prague to Rome.

Yes, the following luggage options are included when booking a bus ticket from Prague to Rome:

FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).

Yes, the following additional luggage options are available when booking a bus ticket from Prague to Rome:

FlixBus
- Additional luggage can be purchased for a fee.

Yes, you can bring your pet on the bus from Prague to Rome. The following conditions apply:

FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.

You can reserve your seat on the bus from Prague to Rome with the following bus company: FlixBus

Yes, there are USB plugs on board the bus from Prague to Rome with the following bus company: FlixBus.

Yes, there is Wifi on board the bus from Prague to Rome with the following bus company: FlixBus.

Since both Prague and Rome are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.

We recommend using the flight as it is the most popular way to get from Prague to Rome among Omio's users.

Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.

In Rome, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, major landmarks, and popular squares. Common scams include unofficial taxi drivers overcharging and street vendors selling counterfeit goods. It's advisable to use authorized taxis, keep valuables secure, and be wary of distraction techniques used by scammers in busy tourist spots.

Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Prague to Rome

Most Prague to Rome buses use the Praha, Hlavní Nádraží to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Prague and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Prague

Arrival bus stations in Rome

Which Prague station do buses to Rome leave from?

Buses from Prague to Rome leave from Praha, Hlavní Nádraží. The station is 0 miles (1 km) from Prague city centre at Wilsonova 300/8, 110 00 Praha 1, Czech Republic.

Praha, Hlavní NádražíWilsonova 300/8, 110 00 Praha 1, Czech Republic Wifi

City-centre transport

Getting to Praha, Hlavní Nádraží from Prague city centre

Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:

TrainRj, 600, 602, 604, 606, 608, 610, 612, 614, 616, 618, 670, 674, 676, 678, 680, 682, 684, 686, 688, 690, 692, 694, 696, 698, 2474, Re · 8m · $1 · every ~3 min

Nj · 8m · $17

Bus478 · 5m

Tram17, 93 · 10m · $2 · every ~23 min

17, 93 · 12m · $2 · every ~23 min

SubwayC · 5m · $2 · every ~29 min

Praha, Hlavní Nádraží bus station facilities and services

Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.

Food and drink

Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).

Wi-Fi and ATMs

Free Wi-Fi. ATMs are located near the main entrance and ticketing area.

Tickets and information

Ticket office support is available at Praha, Hlavní Nádraží.

Parking, taxis and toilets

Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.

More about Praha, Hlavní Nádraží

Praha, ÚAN FlorencKrizikova 6, 186 00 Praha 8-Karlin, Czechia Wifi

City-centre transport

Getting to Praha, ÚAN Florenc from Prague city centre

Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:

Bus207, *888 · 9m · $2 · every ~14 min

Tram3, 24, 31, 92, 94 · 13m · $2 · every ~24 min

SubwayB · 2m · $2 · every ~27 min

Praha, ÚAN Florenc bus station facilities and services

Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.

Food and drink

Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).

Wi-Fi and ATMs

Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.

Tickets and information

Ticket office support is available at Praha, ÚAN Florenc.

Parking, taxis and toilets

Available at Praha, ÚAN Florenc: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.

More about Praha, ÚAN Florenc

Praha, Na KnížecíNa Knizeci, Prague, Czech Republic Wifi

City-centre transport

Getting to Praha, Na Knížecí from Prague city centre

Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:

Bus907, 908 · 16m · $2 · every ~1 min

N109, 084, N1759, N1309, 853, 109 · 20m · $1 · every ~1 min

Tram12, 15, 20 · 11m · $2 · every ~33 min

Praha, Na Knížecí bus station facilities and services

Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.

Food and drink

Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).

Wi-Fi and ATMs

Free Wi-Fi. ATMs are located near the entrance.

Parking, taxis and toilets

Available at Praha, Na Knížecí: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.

More about Praha, Na Knížecí

Praha, Roztyly

City-centre transport

Getting to Praha, Roztyly from Prague city centre

Bus911 · 8m · $2 · every ~1 min

N862, 913, 850, 853, 266, N913, 915 · 25m · $1

135 · 29m · $2 · every ~12 min

SubwayC · 12m · $2 · every ~27 min

Praha, Černý MostBryanska 853/1, 198 00 Praha 14, Czech Republic Wifi

City-centre transport

Getting to Praha, Černý Most from Prague city centre

Praha, Černý Most is 11 km from Prague city centre. Public transport options include:

Bus852, 239, N1315, 855, 1300, 861, 1300A, 1380, N1300, N1307, N1303, 1310, N1380, 1316 · 25m · $1 · every ~2 min

201 · 56m · $2 · every ~11 min

SubwayB · 17m · $2 · every ~27 min

B · 19m · $2 · every ~27 min

Praha, Černý Most bus station facilities and services

Praha, Černý Most has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.

Food and drink

Food options include: Cafeteria Černý Most (in the station), Czech Bistro (in the station), Fast Food Express (in the station).

Wi-Fi and ATMs

Free Wi-Fi. ATMs are located near the entrance and in the main concourse.

Tickets and information

Ticket office support is available at Praha, Černý Most.

Parking, taxis and toilets

Available at Praha, Černý Most: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Praha, Černý Most: Elevators, ramps.

More about Praha, Černý Most

Praha, Zličín

City-centre transport

Getting to Praha, Zličín from Prague city centre

TrainRe · 38m · $2

Bus180 · 27m · $2 · every ~13 min

Tram9, 99, 98 · 31m · $2 · every ~24 min

9, 98, 99 · 32m · $2 · every ~24 min

9, 98 · 39m · $2 · every ~23 min

Praha, M. Horákové (Hradčanská)Milady Horakove 116/109, 160 00 Praha 6-Hradcany, Czech Republic Taxis

City-centre transport

Getting to Praha, M. Horákové (Hradčanská) from Prague city centre

Praha, M. Horákové (Hradčanská) is 1 km from Prague city centre. Public transport options include:

Train17704 · 12m · $1

Bus907, 909 · 7m · $2 · every ~1 min

Tram1, 2, 18, 25, 43, 44 · 9m · $2 · every ~24 min

Praha, M. Horákové (Hradčanská) bus station facilities and services

Praha, M. Horákové (Hradčanská) has practical services for this route, including Taxis.

Parking, taxis and toilets

Available at Praha, M. Horákové (Hradčanská): Taxis.

Praha, Nádraží HolešovicePrague Holesovice Train Station,Partyzanska 1504/24,170 00

City-centre transport

Getting to Praha, Nádraží Holešovice from Prague city centre

TrainRj, 600, 602, 604, 606, 608, 610, 612, 614, 616, 618, 670, 674, 676, 678, 680, 682, 684, 686, 688, 690, 692, 694, 696, 698, 2474, Re · 8m · $1 · every ~3 min

Nj · 8m · $17

Bus478 · 5m

Tram17, 93 · 10m · $2 · every ~23 min

17, 93 · 12m · $2 · every ~23 min

SubwayC · 5m · $2 · every ~29 min

Praha, Letiště Václava Havla

City-centre transport

Getting to Praha, Letiště Václava Havla from Prague city centre

Train59 · 28m · $4 · every ~25 min

BusRegioJet 141103 · 15m · $1 · every ~2 min

Ae, 907 · 32m · $5 · every ~7 min

Shuttle24m · $5 · every ~3 min

21m · $16

Most popular bus connections from Prague

Bus Prague - Český Krumlov

Bus Prague - Kyiv

Bus Prague - Karlovy Vary

Bus Prague - Kaliningrad

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Most popular bus connections to Rome

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Overview: Bus from Prague to Rome

Bus providers: FlixBus from Prague to RomeYou can travel by bus between Prague to Rome with FlixBus for as low as $28 (€23). When you search for schedules and tickets, Omio will show you the best journey

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Complete guide to Rome

Things to do in Rome

Vatican Museums

Galleria Borghese

Capitoline Museums

Colosseum

Roman Forum

Pantheon

Piazza Navona

Spanish Steps

Trastevere

Cacio e Pepe

Carbonara

Amatriciana

La Pergola

Armando Al Pantheon

Roscioli Salumeria Con Cucina

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To the city center

Best option: Walk

FAQs: Bus from Prague to Rome

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popular bus stations

Popular bus stations from Prague to Rome

Which Prague station do buses to Rome leave from?

Getting to Praha, Hlavní Nádraží from Prague city centre

Praha, Hlavní Nádraží bus station facilities and services

Food and drink

Wi-Fi and ATMs