The cheapest and fastest buses from Prague to Rome
Cheapest price
$119
Average price
$150
Fastest journey
19 h 50 m
Average duration
20 h 10 m
Buses per day
42
Distance
923 km
The best way to find a cheap bus ticket from Prague to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Rome will cost around $150 if you buy it on the day, but the cheapest tickets can be found for only $119.
Of the 42 buses that leave Prague for Rome on Fri, Feb 27, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Feb 27 the direct buses cover the 923 km distance in an average of 20 h 10 m but if you time it right, some buses will get you there in just 19 h 50 m .
On Fri, Feb 27 the slowest buses will take 20 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
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FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
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FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Prague to Rome
Omio recommends booking the flight as it is the most popular option from Prague to Rome among Omio's users. If you are prioritising price take the train with prices starting from $29. For those with little time consider booking a flight which can get you there in 3h 34m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a train costs an average of $29, and a flight costs an average of $27.
Distance: 573 miles (923 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$121 Average price | $160 Average price | $29 Average price Cheapest |
15h 9m Average total duration 14h 39m Onboard + 30m Additional time* | 6h 34m Average total duration Fastest 3h 34m Onboard + 3h 0m Additional time* | 20h 10m Average total duration 19h 40m Onboard + 30m Additional time* |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Prague to Rome Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:30AM | Arrival Time 11:00PM | Duration 20h30 | Departure days Mon, Fri, Sat, Sun | Cheapest price $97 |
Operator FlixBus | Departure Time 05:50AM | Arrival Time 09:30AM | Duration 27h40 | Departure days Thu, Fri, Sat, Sun | Cheapest price $109 |
Operator FlixBus | Departure Time 06:20AM | Arrival Time 09:20AM | Duration 27h00 | Departure days Fri, Sat, Sun | Cheapest price $115 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 06:10AM | Duration 22h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $97 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 07:05AM | Duration 23h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $128 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 09:30AM | Duration 25h00 | Departure days Everyday | Cheapest price $97 |
Operator FlixBus | Departure Time 08:55AM | Arrival Time 07:05AM | Duration 22h10 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 09:30AM | Duration 23h50 | Departure days Everyday | Cheapest price $97 |
Operator FlixBus | Departure Time 10:15AM | Arrival Time 02:05PM | Duration 27h50 | Departure days Tue, Fri | Cheapest price $108 |
Operator FlixBus | Departure Time 11:00AM | Arrival Time 02:05PM | Duration 27h05 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $104 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 07:05AM | Duration 19h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $104 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 09:30AM | Duration 20h40 | Departure days Everyday | Cheapest price $97 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 01:20PM | Duration 24h25 | Departure days Wed, Thu, Sat, Sun | Cheapest price $105 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 09:30AM | Duration 20h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $99 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 09:30AM | Duration 19h30 | Departure days Sun | Cheapest price $106 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 12:15PM | Duration 22h00 | Departure days Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 03:05PM | Duration 24h35 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $103 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 03:05PM | Duration 24h05 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $102 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 03:05PM | Duration 23h35 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $102 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 06:45PM | Duration 25h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $98 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 03:05PM | Duration 21h50 | Departure days Mon, Thu, Sun | Cheapest price $102 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 02:05PM | Duration 20h45 | Departure days Everyday | Cheapest price $104 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 03:05PM | Duration 21h35 | Departure days Mon, Thu, Sun | Cheapest price $102 |
Operator FlixBus | Departure Time 05:35PM | Arrival Time 02:05PM | Duration 20h30 | Departure days Everyday | Cheapest price $104 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 03:05PM | Duration 21h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $97 |
Operator Regiojet | Departure Time 06:30PM | Arrival Time 02:45PM | Duration 20h15 | Departure days Mon | Cheapest price $103 |
Operator FlixBus | Departure Time 06:45PM | Arrival Time 11:00PM | Duration 28h15 | Departure days Mon, Fri, Sat | Cheapest price $104 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 06:45PM | Duration 23h50 | Departure days Fri, Sun | Cheapest price $108 |
Operator FlixBus | Departure Time 07:25PM | Arrival Time 06:45PM | Duration 23h20 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $99 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 06:20PM | Duration 22h00 | Departure days Fri, Sat | Cheapest price $108 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 11:00PM | Duration 26h20 | Departure days Mon | Cheapest price $102 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 06:00PM | Duration 20h35 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $97 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 11:00PM | Duration 25h10 | Departure days Thu, Fri, Sat, Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 09:55PM | Arrival Time 08:25PM | Duration 22h30 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $110 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 11:00PM | Duration 24h35 | Departure days Thu, Fri, Sat, Sun | Cheapest price $106 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 11:00PM | Duration 23h25 | Departure days Thu, Fri, Sat | Cheapest price $131 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 11:00PM | Duration 23h20 | Departure days Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 04:00AM | Duration 28h15 | Departure days Thu, Fri, Sat | Cheapest price $97 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 11:00PM | Duration 23h10 | Departure days Thu, Fri, Sat, Sun | Cheapest price $107 |
Live departures
Prague to Rome bus times
The table below shows live departures for Prague to Rome buses for today, Thursday, February 26. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 6:30 AM Prague, Central Train Station | 22h40 | 5:10 AM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:55 AM Praha, Na Knížecí | 23h10 | 6:05 AM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:30 AM Praha, Roztyly | 25h00 | 8:30 AM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:40 AM Praha, Na Knížecí | 23h50 | 8:30 AM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:40 AM Praha, Na Knížecí | 26h35 | 11:15 AM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 10:00 AM Praha, ÚAN Florenc | 20h05 | 6:05 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:00 AM Praha, Roztyly | 27h05 | 1:05 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus | 10:15 AM Prague, Central Train Station | 19h50 | 6:05 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 11:50 AM Praha, ÚAN Florenc | 20h40 | 8:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:50 AM Praha, ÚAN Florenc | 23h25 | 11:15 AM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:50 AM Praha, M. Horákové (Hradčanská) | 26h15 | 2:05 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 11:50 AM Praha, M. Horákové (Hradčanská) | 24h30 | 12:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:55 AM Praha, Zličín | 24h25 | 12:20 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:05 PM Prague, Central Train Station | 23h10 | 11:15 AM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 12:05 PM Prague, Central Train Station | 20h25 | 8:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 1:30 PM Praha, Černý Most | 22h50 | 12:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:30 PM Praha, Černý Most | 24h35 | 2:05 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:10 PM Praha, Roztyly | 25h35 | 5:45 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:15 PM Praha, ÚAN Florenc | 21h50 | 2:05 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus | 4:20 PM Praha, ÚAN Florenc | 20h45 | 1:05 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 4:20 PM Praha, ÚAN Florenc | 24h40 | 5:00 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:30 PM Prague, Central Train Station | 21h35 | 2:05 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus | 4:35 PM Prague, Central Train Station | 20h30 | 1:05 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 4:35 PM Prague, Central Train Station | 24h25 | 5:00 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 4:45 PM Praha, Na Knížecí | 19h35 | 12:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:45 PM Praha, Na Knížecí | 21h20 | 2:05 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:25 PM Praha, Zličín | 23h20 | 5:45 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:50 PM Praha, Na Knížecí | 25h10 | 10:00 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus | 8:55 PM Praha, ÚAN Florenc | 22h30 | 7:25 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:25 PM Praha, M. Horákové (Hradčanská) | 24h35 | 10:00 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus | 10:35 PM Praha, ÚAN Florenc | 23h25 | 10:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 10:45 PM Praha, ÚAN Florenc | 28h15 | 3:00 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 10:50 PM Prague, Central Train Station | 23h10 | 10:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
| Friday, February 27 | |||||
FlixBus · FlixBus | 1:30 AM Prague, Central Train Station | 20h30 | 10:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:50 AM Prague, Central Train Station | 27h40 | 8:30 AM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:20 AM Praha, Černý Most | 27h00 | 8:20 AM Roma, Autostazione Tiburtina | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 26
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Why should you book Prague to Rome buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Rome.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Rome.
Journey information
Overview: Bus from Prague to Rome
Buses from Prague to Rome run on average 38 times per day, taking around 14h 39m. Cheap bus tickets for this journey start at $73 (€58) but you can travel from only $27 (€21) by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 573 miles (923 km) distance in 19h 15m.
Distance 573 miles (923 km) |
Average bus duration 14h 39m |
Cheapest ticket price $73 (€58) |
Buses per day 38 |
Direct buses 2 |
Fastest bus 19h 15m |
First bus 00:10 |
Last bus 23:50 |
Bus providers: FlixBus from Prague to RomeYou can travel by bus between Prague to Rome with FlixBus for as low as $27 (€21). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Prague to Rome
Find answers to the most common questions about traveling from Prague to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- ÖBB Nightjet
- Wheelchair spaces, accessible toilets, boarding assistance available with advance notice
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- KM Malta Airlines
- Assistance available for passengers with reduced mobility, must be requested at least 48h before departure
- Colosseum, an ancient amphitheater known for its gladiatorial contests and iconic architecture
- Vatican Museums, a vast collection of art and historical artifacts including the Sistine Chapel
- Roman Forum, the ruins of ancient Rome's center for public life and government
- Pantheon, a well-preserved Roman temple with a striking dome and oculus
- Trevi Fountain, a famous Baroque fountain where visitors traditionally toss coins for good luck.
- Explore Trastevere, a charming neighborhood with narrow streets and vibrant nightlife
- Take a stroll through Villa Borghese, a beautiful park with museums and gardens
- Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists
- Visit the Spanish Steps, a popular spot for people-watching and enjoying the view
- Discover the Catacombs, ancient underground burial sites with guided tours.
- ÖBB Nightjet
- Cancellation possible according to ticket type conditions
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- KM Malta Airlines
- Free cancellation within 24h of booking if flight is more than 7 days away
- ÖBB Nightjet
- 2 pieces of hand luggage and 1 piece of larger luggage included
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- KM Malta Airlines
- 1 small personal item (40x20x25 cm) included
- FlixBus
- Additional luggage can be purchased for a fee.
- KM Malta Airlines
- Additional cabin bag (55x40x20 cm) and checked baggage available for purchase
- ÖBB Nightjet
- Small pets in carriers travel free. Larger dogs need ticket (50% of 2nd class fare) and muzzle. Guide dogs free.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- KM Malta Airlines
- Small pets in cabin allowed, max 8kg including carrier
popular bus stations
Popular bus stations from Prague to Rome
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
More options for your journey from Prague to Rome
Here are some other resources that might have the information you need


