Chicago, IL to San Francisco, CA bus with Greyhound

Thu, Sep 17
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The cheapest and fastest buses from Chicago, IL to San Francisco, CA

Showing times, prices and bookable tickets for Sep 17

Cheapest price on Sep 17

$396

Average ticket price on Sep 17

$423

Fastest journey on Sep 17

2 d 2 h 10 m

Average journey duration on Sep 17

2 d 9 h 14 m

Buses on Sep 17

5

Distance

2983 km

Cheap tickets

The best way to find a cheap bus ticket from Chicago, IL to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Chicago, IL to San Francisco, CA will cost around $423 if you buy it on the day, but the cheapest tickets can be found for only $396.

Fast buses

It's difficult to get from Chicago, IL to San Francisco, CA without transferring at least 2 times.

  • Greyhound · ·
    12:25 PM50h10
    Chicago, Greyhound Bus Station
    12:35 PMSan Francisco, Transit Center Bay 29
    $3961One-way
    2 transfers
  • Greyhound · · ·
    11:10 PM59h35
    Chicago, Union Station (Amtrak), IL
    8:45 AMSan Francisco, Townsend Street / 5th Street, CA
    $4011One-way
    4 transfers
  • Greyhound · · ·
    10:50 PM59h55
    Chicago, Greyhound Bus Station
    8:45 AMSan Francisco, Townsend Street / 5th Street, CA
    $4031One-way
    4 transfers
  • Greyhound · · ·
    11:10 PM58h00
    Chicago, Union Station (Amtrak), IL
    7:10 AMSan Francisco, Transit Center Bay 29
    $4461One-way
    4 transfers
  • FlixBusFlixBus+Greyhound · +FlixBusFlixBus
    12:15 AM58h30
    Chicago, Greyhound Bus Station
    8:45 AMSan Francisco, Townsend Street / 5th Street, CA
    $4661One-way
    3 transfers

Travel Information

Compare bus, train, and flight for Chicago, IL to San Francisco, CA

Omio recommends booking the train as it is the most popular option from Chicago, IL to San Francisco, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $326 For those with little time, consider booking a flight, which has an average total journey time of 8h 31m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.9 - 2.7kg. Average ticket prices depend on the travel mode: a bus costs an average of $326, while a flight costs an average of $582.

Distance: 1853 miles (2983 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$326

Average price

Cheapest

$449

Average price

$582

Average price

$457

Average price

(fuel + tolls)

53h 40m

Average total duration

53h 10m

Onboard

+

30m

Additional time*

56h 57m

Average total duration

56h 27m

Onboard

+

30m

Additional time*

8h 31m

Average total duration

Fastest

6h 31m

Onboard

+

2h 0m

Additional time*

31h 15m

Average total duration

(door-to-door)

3.0 - 7.5kg

CO2 emissions

0.9 - 2.7kg

CO2 emissions

Lowest

8.9 - 17.9kg

CO2 emissions

-

CO2 emissions

Greyhound

Most popular bus company

Amtrak

Most popular train company

United

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Chicago, IL to San Francisco, CA is a bus with an average price of $326 (€265).

This is compared to other travel options from Chicago, IL to San Francisco, CA:

A bus is $123 (€100) less than a train for this route with tickets for a train from Chicago, IL to San Francisco, CA costing on average $449 (€365).

A bus is $256 (€208) less than a flight for this route with tickets for a flight from Chicago, IL to San Francisco, CA costing on average $582 (€473).

The fastest way to travel from Chicago, IL to San Francisco, CA is by flight with an average journey time of 6h 31m.

Other travel options to San Francisco, CA take longer:

Bus takes on average 53h 10m.

Train takes on average 56h 27m.

It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and San Francisco, CA including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Chicago, IL to San Francisco, CA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $326 (€265) compared to roughly $457 (€371) in fuel and tolls — a saving of about $130 (€106). The journey takes 53h 10m versus 31h 15m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Chicago, IL to San Francisco, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:15AM
Arrival Time
08:45AM
Duration
58h30
Departure days
Mon, Thu, Sat, Sun
Cheapest price
$227
Operator
Greyhound
Departure Time
04:10AM
Arrival Time
02:15PM
Duration
58h05
Departure days
Sat
Cheapest price
$493
Operator
Greyhound
Departure Time
12:25PM
Arrival Time
12:35PM
Duration
50h10
Departure days
Mon, Tue, Wed, Thu, Sat, Sun
Cheapest price
$192
Operator
Greyhound
Departure Time
05:01PM
Arrival Time
07:25PM
Duration
50h24
Departure days
Fri
Cheapest price
$654
Operator
Greyhound
Departure Time
05:25PM
Arrival Time
12:35AM
Duration
55h10
Departure days
Fri
Cheapest price
$471
Operator
Greyhound
Departure Time
06:01PM
Arrival Time
08:25PM
Duration
50h24
Departure days
Fri
Cheapest price
$553
Operator
Greyhound
Departure Time
10:50PM
Arrival Time
08:45AM
Duration
59h55
Departure days
Mon, Tue, Wed, Thu, Sat, Sun
Cheapest price
$223
Operator
Greyhound
Departure Time
11:10PM
Arrival Time
07:10AM
Duration
58h00
Departure days
Mon, Tue, Wed, Thu, Sat, Sun
Cheapest price
$226

Live departures

Chicago, IL to San Francisco, CA bus times

The table below shows live departures for Chicago, IL to San Francisco, CA buses for today, Wednesday, September 16. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · · 12:25 PM Chicago, Greyhound Bus Station
50h10
12:35 PM San Francisco, Transit Center Bay 292 transfers
Greyhound · · · 10:50 PM Chicago, Greyhound Bus Station
59h55
8:45 AM San Francisco, Townsend Street / 5th Street, CA4 transfers
Greyhound · · · 11:10 PM Chicago, Union Station (Amtrak), IL
59h35
8:45 AM San Francisco, Townsend Street / 5th Street, CA4 transfers
Greyhound · · · 11:10 PM Chicago, Union Station (Amtrak), IL
58h00
7:10 AM San Francisco, Transit Center Bay 294 transfers
Thursday, September 17
FlixBusFlixBus+Greyhound · +FlixBusFlixBus12:15 AM Chicago, Greyhound Bus Station
58h30
8:45 AM San Francisco, Townsend Street / 5th Street, CA3 transfers

Find all the dates and times for this journey

Compare prices and tickets Chicago, IL to San Francisco, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Chicago, IL to San Francisco, CA buses with Omio?

Greyhound as well as FlixBus offer buses services from Chicago, IL to San Francisco, CA.
Omio is an official ticket reseller for all your travel options from Chicago, IL to San Francisco, CA.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Chicago, IL to San Francisco, CA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Chicago, IL to San Francisco, CA.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Chicago, IL to San Francisco, CA.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Chicago, IL to San Francisco, CA.

Journey information

Overview: Bus from Chicago, IL to San Francisco, CA

USAUSA
USAUSA
Icon of bus

Buses from Chicago, IL to San Francisco, CA run on average 4 times per day, taking around 53h 10m. Cheap bus tickets for this journey start at $136 (€110) but you can travel from only $78 (€63) by flight.

The earliest bus runs at 00:15, the last at 23:50. The fastest bus covers the 1853 miles (2983 km) distance in 48h 4m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $78 (€63)
Distance
1853 miles (2983 km)
Average bus duration
53h 10m
Cheapest ticket price
$136 (€110)
Buses per day
4
Fastest bus
48h 4m
First bus
12:15 AM
Last bus
11:50 PM
Cheapest Month
Jul
Cheapest Day
Sun
High Season
Jan - Mar
Low Season
Jul - Sep
Busiest Day
Fri
Least Busy Day
Mon
Best time to book
28 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $78 (€63)

Bus providers: Greyhound from Chicago, IL to San Francisco, CAYou can travel by bus between Chicago, IL to San Francisco, CA with Greyhound for as low as $78 (€63). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
48h 4m
Cheapest Greyhound Price
$136 (€110)
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to San Francisco, CA

Things to do in San Francisco, CA

Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.

  • Must visit

California Academy of Sciences

Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.

  • Must visit

de Young Museum

Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.

  • Must visit

San Francisco Museum of Modern Art

Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.

US Dollar ($)

Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.

Average meal costs

Budget
$12-20 for fast food or casual takeout.
Mid-range
$25-45 per person for a restaurant meal.
Fine dining
$90+ per person for upscale dining.
Coffee
$4-7 for coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.

FAQs: Bus from Chicago, IL to San Francisco, CA

Find answers to the most common questions about traveling from Chicago, IL to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Chicago, IL to San Francisco, CA can start from as little as $136 (€110) when you book in advance. The average bus ticket price for Chicago, IL to San Francisco, CA is $326 (€265) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Chicago, IL to San Francisco, CA is 48h 4m to travel the 1853 miles (2983 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Chicago, IL to San Francisco, CA leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Chicago, IL to San Francisco, CA leaves at 11:50 PM.
There are 4 buses a day from Chicago, IL to San Francisco, CA which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Chicago, IL to San Francisco, CA, you can count on Greyhound, FlixBus for the best way to get you to San Francisco, CA. You can also check all possible bus companies who offer a service between Chicago, IL and San Francisco, CA and compare the amenities they offer before buying a bus ticket.
When departing from Chicago, IL , you have various bus station options to start your journey from including Chicago, Greyhound Bus Station, Chicago, Union Station (Amtrak), IL, Chicago, Cumberland Blue Line Station, IL . When arriving in San Francisco, CA , you can end your journey in bus stations like San Francisco, Townsend Street / 5th Street, CA, San Francisco, Transit Center Bay 29, Oakland, West Oakland BART Station, CA .Passengers board the bus most frequently from Chicago, Greyhound Bus Station, which is located around 1 miles (2 km) away from the city centre, and they get off the bus at San Francisco, Townsend Street / 5th Street, CA, located 0 away from the city centre.
A trip to San Francisco, CA from Chicago, IL is worth doing but not as a day trip with a journey time of 48h 4m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Chicago, IL to San Francisco, CA is July.
It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and San Francisco, CA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Chicago, IL to San Francisco, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Chicago, IL to San Francisco, CA for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in San Francisco, CA are:
  • Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
  • Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
  • Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
  • Golden Gate Park, a large urban park with gardens, museums, and recreational activities
  • Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
The best things to do in San Francisco, CA include:
  • Ride a cable car through the steep streets of San Francisco for a classic city experience
  • Explore the vibrant murals and street art in the Mission District
  • Visit the Exploratorium, an interactive science museum perfect for all ages
  • Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
  • Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
Whether you can cancel your bus ticket from Chicago, IL to San Francisco, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Chicago, IL to San Francisco, CA.
Yes, the following luggage options are included when booking a bus ticket from Chicago, IL to San Francisco, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Chicago, IL to San Francisco, CA:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Chicago, IL to San Francisco, CA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Chicago, IL to San Francisco, CA with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Chicago, IL to San Francisco, CA with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Chicago, IL to San Francisco, CA with the following bus company: Greyhound, FlixBus.
Since neither Chicago, IL nor San Francisco, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Chicago, IL to San Francisco, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Francisco, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Fisherman's Wharf and Union Square. Common scams include distraction techniques used by groups to steal wallets and fake charity solicitations. It's advisable to avoid poorly lit or isolated areas at night and be wary of unofficial taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Chicago, IL to San Francisco, CA

Most Chicago, IL to San Francisco, CA buses use the Chicago, Greyhound Bus Station to San Francisco, Townsend Street / 5th Street station pair, with some services arriving at San Francisco, Transit Center Bay 29. Use this guide to compare Chicago, IL and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Chicago
Arrival bus stations in San Francisco

Which Chicago, IL station do buses to San Francisco, CA leave from?

Buses from Chicago, IL to San Francisco, CA leave from Chicago, Greyhound Bus Station. The station is 1 miles (3 km) from Chicago, IL city centre at 630 W Harrison St, Chicago, IL 60607, USA.
Chicago, Greyhound Bus Station630 W Harrison St, Chicago, IL 60607, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Chicago, Greyhound Bus Station from Chicago city centre

Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:

Bus7 · 8m · $4 · every ~6 min

Chicago, Greyhound Bus Station bus station facilities and services

Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Snack shop and vending machines available

Wi-Fi and ATMs

Free Wi-Fi in waiting area. ATMs are located near entrance.

Tickets and information

Ticket office support is available at Chicago, Greyhound Bus Station.

Parking, taxis and toilets

Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.

Chicago, Union Station (Amtrak)Chicago Union Station, 225 S Canal St, Chicago, IL 60606, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Chicago, Union Station (Amtrak) from Chicago city centre

Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:

Bus28, 151 · 7m · $4 · every ~13 min

Chicago, Union Station (Amtrak) bus station facilities and services

Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Multiple dining options are available inside the station.

Wi-Fi and ATMs

Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.

Tickets and information

Ticket office support is available at Chicago, Union Station (Amtrak).

Parking, taxis and toilets

Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.

Chicago, Cumberland Blue Line StationCumberland Blue Line Station, Chicago, IL 60631, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Chicago, Cumberland Blue Line Station from Chicago city centre

Chicago, Cumberland Blue Line Station is 21 km from Chicago city centre. Public transport options include:

BusGreyhound US0150S · 30m · $2
SubwayBlue Line · 39m · $6 · every ~23 min

Chicago, Cumberland Blue Line Station bus station facilities and services

Chicago, Cumberland Blue Line Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Chicago, Cumberland Blue Line Station. ATMs are available at Chicago, Cumberland Blue Line Station.

Tickets and information

Ticket office support is available at Chicago, Cumberland Blue Line Station.

Parking, taxis and toilets

Available at Chicago, Cumberland Blue Line Station: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Chicago, Cumberland Blue Line Station: Wheelchair accessible with elevator service.

Most popular buses to and from San Francisco, CA and Chicago, IL

HomeBusesBuses in USABus tickets to San Francisco, CAChicago, IL to San Francisco, CA bus

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