Travel Information from St. Louis, MO to San Antonio, TX
| 791 miles (1276 km) | |
| Train, bus or flight | |
| $326 - $96 | |
| Bus • $96 (€87) • 22 h 30 min | |
| Bus • $96 (€87) • 22 h 30 min | |
| Greyhound or Amtrak |
Take a train, bus or flight to travel 791 miles (1276 km) between St. Louis, MO and San Antonio, TX. The most popular travel companies which serve this journey are Greyhound or Amtrak among others. Travelers can even take a direct bus or train from St. Louis, MO to San Antonio, TX.
Travel optionsfrom St. Louis, MO to San Antonio, TX
How to get from St. Louis, MO to San Antonio, TX by train, bus or flight.
Our recommendation
The best way to travel from St. Louis, MO to San Antonio, TX is by taking a train because it’s the best combination of price and speed.

Cheapest

Fastest

Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from St. Louis, MO to San Antonio, TX
Travel to San Antonio, TX easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from St. Louis, MO to San Antonio, TX.

There are 3 travel options from St. Louis, MO to San Antonio, TX. You can take a train, bus or flight.
The cheapest way to travel between St. Louis, MO and San Antonio, TX is a bus with an average price of $96 (€87).
This is compared to other travel options from St. Louis, MO to San Antonio, TX:
A bus is () less than a flight for this route with tickets for a flight from St. Louis, MO to San Antonio, TX costing on average ().
Taking a bus costs $229 (€207) less than taking a train, which average ticket prices of $326 (€294).
The fastest way from St. Louis, MO to San Antonio, TX is by bus with an average journey time of 22 h 30 min.
There are alternative travel options to San Antonio, TX that take longer:
Train takes 26 h on average.
The distance from St. Louis, MO to San Antonio, TX is approximately 791 miles (1276 km).
The average frequency per day from St. Louis, MO to San Antonio, TX is:
- Around 3 buses per day.
- Around 20 flights per day.
- 1 train per day.
However, we recommend checking specific travel dates for your route between St. Louis, MO and San Antonio, TX as scheduled services by train, bus or flight can vary by season or day of the week.
These are the most popular departure and arrival points from St. Louis, MO to San Antonio, TX:
Omio works with many trusted partners that can help you travel the best way from St. Louis, MO to San Antonio, TX:
- You can travel by bus to San Antonio, TX from St. Louis, MO with Greyhound, and you can find Greyhound St. Louis, MO to San Antonio, TX tickets for $96 (€87) on Omio.
- You can take a train from St. Louis, MO to San Antonio, TX with Amtrak. Cheap tickets can be found for $326 (€294) with Amtrak from St. Louis, MO to San Antonio, TX.
Yes, there are direct routes from St. Louis, MO to San Antonio, TX with the following travel companies:
- You can check for a direct train to San Antonio, TX with Amtrak with 1 direct train per day.
Direct services to San Antonio, TX tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your journey.
Travelling from St. Louis, MO to San Antonio, TX: related information
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