- Must visit
San Antonio Museum of Art
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
Cheapest price
$145
Average price
$151
Fastest journey
21 h 20 m
Average duration
1 d 10 m
Buses per day
2
Distance
1291 km
The best way to find a cheap bus ticket from Denver, CO to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Denver, CO to San Antonio, TX will cost around $151 if you buy it on the day, but the cheapest tickets can be found for only $145.
It's difficult to get from Denver, CO to San Antonio, TX without transferring at least once.
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FlixBus+
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FlixBus+
Omio recommends booking the bus as it is the most popular option from Denver, CO to San Antonio, TX among Omio's users. If you are prioritising price take the bus with prices starting from $111. For those with little time consider booking a flight which can get you there in 2h 44m. The ticket price range depends on the travel mode: a bus costs an average of $111, and a train costs an average of $306.
Distance: 802 miles (1291 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$210 Average price Cheapest | $453 Average price | $540 Average price | $187 Average price (fuel + tolls) |
20h 38m Average total duration 20h 8m Onboard + 30m Additional time* | 5h 44m Average total duration Fastest 2h 44m Onboard + 3h 0m Additional time* | 44h 27m Average total duration 43h 57m Onboard + 30m Additional time* | 13h 45m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Denver, CO to San Antonio, TX:
A bus is $243 (€200) less than a flight for this route with tickets for a flight from Denver, CO to San Antonio, TX costing on average $453 (€373).
A bus is $330 (€271) less than a train for this route with tickets for a train from Denver, CO to San Antonio, TX costing on average $540 (€444).
Other travel options to San Antonio, TX take longer:
Bus takes on average 20h 8m.
Train takes on average 43h 57m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:10PM | Arrival Time 06:10PM | Duration 27h00 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $146 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 06:30PM | Duration 21h20 | Departure days Everyday | Cheapest price $145 |
The table below shows live departures for Denver, CO to San Antonio, TX buses for today, Tuesday, July 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 2:10 PM Denver, Union Station | 27h00 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 1 transfer | |
· | 8:10 PM Denver, Union Station | 21h20 | 6:30 PM San Antonio, N St Mary's St (Greyhound), TX | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Denver, CO to San Antonio, TX run on average 2 times per day, taking around 20h 8m. Cheap bus tickets for this journey start at $111 (€91) if you book in advance.
The earliest bus runs at 01:30, the last at 21:15. The fastest bus covers the 802 miles (1291 km) distance in 21h 20m.
Distance 802 miles (1291 km) |
Average bus duration 20h 8m |
Cheapest ticket price $111 (€91) |
Buses per day 2 |
Fastest bus 21h 20m |
First bus 1:30 AM |
Last bus 9:15 PM |
Cheapest Month Jan |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Apr - Jun |
Best time to book 28 days |
Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.
Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.
The city’s signature pedestrian corridor links shops, boats, bridges, and historic architecture, making it San Antonio’s essential walking experience.
This artsy, fast-evolving district mixes galleries, murals, boutiques, and nightlife with a strong local identity near the river.
A lively downtown plaza framed by major civic buildings, it is best known for events, fountains, and the nightly cathedral light show nearby.
Puffy tacos are San Antonio’s signature dish: crisp, airy fried corn tortillas filled with picadillo, chicken, or beans, rooted in local Tex-Mex history.
Barbacoa is slow-cooked beef, often served on weekends in breakfast tacos. It is a beloved South Texas tradition with deep Mexican roots.
Breakfast tacos are a daily staple in San Antonio, usually filled with egg, potato, bean, bacon, or chorizo in flour or corn tortillas.
Refined River Walk restaurant serving upscale South Texas and Mexican cuisine. Elegant atmosphere with a long-standing fine dining reputation.
Popular breakfast and lunch spot known for house-made tortillas, tacos, and classic San Antonio Tex-Mex in a relaxed setting.
Beloved market restaurant for authentic Mexican dishes, fresh tortillas, and bakery items. Bustling, traditional atmosphere.
Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.
Official public transport app
UTSA East Campus Lot 1 -> Downtown San Antonio
Find answers to the most common questions about traveling from Denver, CO to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

Most Denver, CO to San Antonio, TX buses use the Denver, Union Station to San Antonio, N St Mary's St (Greyhound) station pair. Use this guide to compare Denver, CO and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need