- Must visit
The Andy Warhol Museum
A vast contemporary art museum founded by Andy Warhol, featuring immersive exhibitions and the largest collection of his work and archives.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from St. Louis, MO to Pittsburgh, PA
Showing times and prices for Aug 05
Cheapest price
$66
Average price
$77
Fastest journey
12 h 55 m
Average duration
16 h 50 m
Buses per day
5
Distance
897 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Pittsburgh, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Pittsburgh, PA will cost around $77 if you buy it on the day, but the cheapest tickets can be found for only $66.
Fast buses
Of the 5 buses that leave St. Louis, MO for Pittsburgh, PA on Wed, Aug 05, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct buses cover the 897 km distance in an average of 16 h 50 m but if you time it right, some buses will get you there in just 12 h 55 m .
On Wed, Aug 05 the slowest buses will take 1 d 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:55 PM12h55St. Louis, S 15th St (Civic center)3:50 AMPittsburgh, Greyhound Bus Station, PA$661One-way0 transfers- 2:00 AM14h45St. Louis, S 15th St (Civic center)5:45 PMPittsburgh, Greyhound Bus Station, PA$661One-way0 transfers
- 8:45 AM14h14St. Louis, S 15th St (Civic center)11:59 PMPittsburgh, Greyhound Bus Station, PA$661One-way0 transfers
FlixBus+11:30 PM17h30St. Louis, S 15th St (Civic center)6:00 PMPittsburgh, Greyhound Bus Station, PA$871One-way1 transfer- FlixBus+ · 4:00 PM24h45St. Louis, S 15th St (Civic center)5:45 PMPittsburgh, Greyhound Bus Station, PA$991One-way2 transfers
- 1:55 PM12h55St. Louis, S 15th St (Civic center)3:50 AMPittsburgh, Greyhound Bus Station, PA$661One-way0 transfers
- 8:45 AM14h14St. Louis, S 15th St (Civic center)11:59 PMPittsburgh, Greyhound Bus Station, PA$661One-way0 transfers
- 2:00 AM14h45St. Louis, S 15th St (Civic center)5:45 PMPittsburgh, Greyhound Bus Station, PA$661One-way0 transfers
- FlixBus+11:30 PM17h30St. Louis, S 15th St (Civic center)6:00 PMPittsburgh, Greyhound Bus Station, PA$871One-way1 transfer
- FlixBus+ · 4:00 PM24h45St. Louis, S 15th St (Civic center)5:45 PMPittsburgh, Greyhound Bus Station, PA$991One-way2 transfers
Travel Information
Compare train, bus, and flight for St. Louis, MO to Pittsburgh, PA
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Pittsburgh, PA among Omio's users. If you are prioritising price take the bus with prices starting from $70. For those with little time consider booking a flight which can get you there in 5h 56m. The ticket price range depends on the travel mode: a bus costs an average of $70, and a train costs an average of $166.
Distance: 557 miles (897 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$108 Average price Cheapest | $306 Average price | $240 Average price | $122 Average price (fuel + tolls) |
14h 52m Average total duration 14h 22m Onboard + 30m Additional time* | 15h 29m Average total duration 14h 59m Onboard + 30m Additional time* | 8h 56m Average total duration Fastest 5h 56m Onboard + 3h 0m Additional time* | 9h 7m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from St. Louis, MO to Pittsburgh, PA is a bus with an average price of $108.
This is compared to other travel options from St. Louis, MO to Pittsburgh, PA:
A bus is $132 less than a flight for this route with tickets for a flight from St. Louis, MO to Pittsburgh, PA costing on average $240.
A bus is $198 less than a train for this route with tickets for a train from St. Louis, MO to Pittsburgh, PA costing on average $306.
The fastest way to travel from St. Louis, MO to Pittsburgh, PA is by flight with an average journey time of 5h 56m.
Other travel options to Pittsburgh, PA take longer:
Bus takes on average 14h 22m.
Train takes on average 14h 59m.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Pittsburgh, PA including taking a train, bus, and flight.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Pittsburgh, PA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $108 compared to roughly $122 in fuel and tolls — a saving of about $14. The journey takes 14h 22m versus 9h 7m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
St. Louis, MO to Pittsburgh, PA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 05:45PM | Duration 14h45 | Departure days Everyday | Cheapest price $60 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 11:59PM | Duration 14h14 | Departure days Everyday | Cheapest price $60 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 03:50AM | Duration 12h55 | Departure days Everyday | Cheapest price $60 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 05:45PM | Duration 24h45 | Departure days Everyday | Cheapest price $96 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 06:00PM | Duration 17h30 | Departure days Everyday | Cheapest price $87 |
Live departures
St. Louis, MO to Pittsburgh, PA bus times
The table below shows live departures for St. Louis, MO to Pittsburgh, PA buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:55 PM St. Louis, S 15th St (Civic center) | 12h55 | 3:50 AM Pittsburgh, Greyhound Bus Station, PA | 0 transfersDirect | |
| FlixBus+ · | 4:00 PM St. Louis, S 15th St (Civic center) | 24h45 | 5:45 PM Pittsburgh, Greyhound Bus Station, PA | 2 transfers | |
| FlixBus+ | 11:30 PM St. Louis, S 15th St (Civic center) | 17h30 | 6:00 PM Pittsburgh, Greyhound Bus Station, PA | 1 transfer | |
| Wednesday, August 5 | |||||
| 2:00 AM St. Louis, S 15th St (Civic center) | 14h45 | 5:45 PM Pittsburgh, Greyhound Bus Station, PA | 0 transfersDirect | |
| 8:45 AM St. Louis, S 15th St (Civic center) | 14h14 | 11:59 PM Pittsburgh, Greyhound Bus Station, PA | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Pittsburgh, PA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Wed
Aug 05
Aug 05
Thu
Aug 06
Aug 06
Fri
Aug 07
Aug 07
Sat
Aug 08
Aug 08
Sun
Aug 09
Aug 09
Mon
Aug 10
Aug 10
Tue
Aug 11
Aug 11
Why should you book St. Louis, MO to Pittsburgh, PA buses with Omio?
Greyhound operates all buses services from St. Louis, MO to Pittsburgh, PA.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Pittsburgh, PA.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Pittsburgh, PA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Pittsburgh, PA.
Journey information
Overview: Bus from St. Louis, MO to Pittsburgh, PA
USAUSA
Buses from St. Louis, MO to Pittsburgh, PA run on average 4 times per day, taking around 14h 22m. Cheap bus tickets for this journey start at $70 if you book in advance.
There are 3 buses per day. The earliest bus runs at 01:15, the last at 23:30. The fastest bus covers the 557 miles (897 km) distance in 12h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 557 miles (897 km) |
Average bus duration 14h 22m |
Cheapest ticket price $70 |
Buses per day 4 |
Direct buses 3 |
Fastest bus 12h 55m |
First bus 1:15 AM |
Last bus 11:30 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Mon |
Best time to book 3 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from St. Louis, MO to Pittsburgh, PAYou can travel by bus between St. Louis, MO to Pittsburgh, PA with Greyhound for as low as $70. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
12h 55m
Cheapest Price
$70
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Pittsburgh, PA
Things to do in Pittsburgh, PA
Discover the best of Pittsburgh, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Pittsburgh, PA trip today.
- Must visit
Carnegie Museum of Natural History
A major natural history museum with dinosaur halls, gems, and world cultures, ideal for understanding science and exploration in one landmark institution.
- Must visit
Carnegie Museum of Art
A respected fine arts museum with European masters, decorative arts, and rotating exhibitions in the historic Carnegie museum complex.
- Must visit
Point State Park
A riverfront state park at Pittsburgh's founding point, famous for the fountain, fort history, and sweeping views where three rivers meet.
- Must visit
Grandview Avenue
A hillside observation terrace on Mount Washington delivering one of America's classic city panoramas, especially memorable at sunset or night.
- Must visit
Penn Avenue in the Strip District
A revitalized Strip District street lined with markets, shops, murals, and energy that captures the city's old warehouse district character.
Primanti-Style Sandwich
A towering deli sandwich packed with grilled meat, coleslaw, tomatoes, and fries inside Italian bread. It became a Pittsburgh icon at Primanti Bros.
- Vegetarian
Pierogi Bread
Soft Italian bread stuffed with seasoned potatoes and onions. Brought by Italian immigrants, it remains a beloved bakery staple around Pittsburgh.
- Vegetarian
Pierogies
Dough pockets usually filled with potato and cheese, then boiled or fried with onions. Pittsburgh celebrates them through strong Eastern European roots.
Pierogies Plus
Beloved casual spot specializing in handmade pierogies with many fillings and toppings. A local favorite for classic Pittsburgh comfort food.
The Vandal
Acclaimed fine-dining destination in Lawrenceville with seasonal tasting menus, polished service, and one of the city’s strongest culinary reputations.
Penn Brewery
Long-running brewery and restaurant serving German and local beers, sausages, and hearty fare. Traditional atmosphere in a landmark North Side building.
US Dollar ($)
Moderate for U.S. city breaks: hotels and dining are mid-priced, transit is affordable, and attractions are often cheaper than in New York or San Francisco.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, about 10-15% for taxis, and $1-2 per drink or coffee in cafes if service is provided.
FAQs: Bus from St. Louis, MO to Pittsburgh, PA
Find answers to the most common questions about traveling from St. Louis, MO to Pittsburgh, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pittsburgh, PA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Pittsburgh, PA can start from as little as $70 when you book in advance. The average bus ticket price for St. Louis, MO to Pittsburgh, PA is $108 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Pittsburgh, PA is 12h 55m to travel the 557 miles (897 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Pittsburgh, PA leaves at 1:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Pittsburgh, PA leaves at 11:30 PM.
Yes, there are 3 direct buses a day from St. Louis, MO to Pittsburgh, PA with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from St. Louis, MO to Pittsburgh, PA, you can count on Greyhound for the best way to get you to Pittsburgh, PA. You can also check all possible bus companies who offer a service between St. Louis, MO and Pittsburgh, PA and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at Pittsburgh, Greyhound Bus Station, PA, located 0 away from the city centre.
A trip to Pittsburgh, PA from St. Louis, MO is worth doing but not as a day trip with a journey time of 12h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Pittsburgh, PA is September.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Pittsburgh, PA including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from St. Louis, MO to Pittsburgh, PA for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Pittsburgh, PA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Pittsburgh, PA are:
- The Andy Warhol Museum, a comprehensive collection dedicated to the life and works of the iconic pop artist
- Phipps Conservatory and Botanical Gardens, a historic greenhouse with diverse plant exhibits and sustainable architecture
- Carnegie Museum of Natural History, featuring extensive dinosaur displays and global cultural artifacts
- Point State Park, a scenic urban park at the confluence of three rivers with historical significance
- Mount Washington, offering panoramic views of Pittsburgh's skyline from its renowned overlooks.
The best things to do in Pittsburgh, PA include:
- Heinz History Center, an affiliate of the Smithsonian Institution showcasing Western Pennsylvania's history and heritage
- Take a ride on the Duquesne Incline for a historic cable car experience and stunning city views
- Explore the Strip District, known for its vibrant markets, eateries, and unique shops
- Visit the National Aviary, home to a diverse collection of birds from around the world
- Enjoy a Pittsburgh Pirates game at PNC Park, renowned for its beautiful views of the city skyline.
Whether you can cancel your bus ticket from St. Louis, MO to Pittsburgh, PA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Pittsburgh, PA.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Pittsburgh, PA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Pittsburgh, PA:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to Pittsburgh, PA.
You can reserve your seat on the bus from St. Louis, MO to Pittsburgh, PA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to Pittsburgh, PA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to Pittsburgh, PA with the following bus company: Greyhound.
Since neither St. Louis, MO nor Pittsburgh, PA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Pittsburgh, PA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Pittsburgh, PA, travelers should be cautious of pickpocketing and theft, especially in crowded areas like downtown and major attractions. Avoid unlicensed transportation services and be aware of common scams such as overcharging by taxi drivers or unofficial tour operators. It's advisable to keep personal belongings secure and use reputable transportation options to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Pittsburgh, PA
Most St. Louis, MO to Pittsburgh, PA buses use the St. Louis, S 15th St (Civic center) to Pittsburgh, Greyhound Bus Station station pair. Use this guide to compare St. Louis, MO and Pittsburgh, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in Pittsburgh
Which St. Louis, MO station do buses to Pittsburgh, PA leave from?
Buses from St. Louis, MO to Pittsburgh, PA leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Which Pittsburgh, PA station do buses from St. Louis, MO arrive at?
Buses from St. Louis, MO to Pittsburgh, PA arrive at Pittsburgh, Greyhound Bus Station. Pittsburgh, Greyhound Bus Station is 0 miles (1 km) from Pittsburgh, PA city centre.
Pittsburgh, Greyhound Bus Station55 11th St, Pittsburgh, PA 15222, USA
City-centre transport
Getting to Pittsburgh, Greyhound Bus Station from Pittsburgh city centre
Bus29, 31, 39, 40, 41, 44, G3, G31, P1 · 3m · every ~27 min
M · 7m
1F, 2F, 3F, 14F · 12m · $1
Pittsburgh, Greyhound Bus Station bus station facilities and services
Pittsburgh, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack bar available on site
Wi-Fi and ATMs
Available throughout the station. ATMs are aTM located near the entrance.
Tickets and information
Ticket office support is available at Pittsburgh, Greyhound Bus Station.
Parking, taxis and toilets
Available at Pittsburgh, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Pittsburgh, Greyhound Bus Station: Wheelchair accessible entrances.
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Pittsburgh, PA
Here are some other resources that might have the information you need
Most popular buses to and from Pittsburgh, PA and St. Louis, MO
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
