- Must visit
The Andy Warhol Museum
A vast contemporary art museum founded by Andy Warhol, featuring immersive exhibitions and the largest collection of his work and archives.
Omio recommends booking the flight as it is the most popular option from San Francisco, CA to Pittsburgh, PA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $287 For those with little time, consider booking a flight, which has an average total journey time of 9h 10m. Average ticket prices depend on the travel mode: a bus costs an average of $287, while a train costs an average of $836.
Distance: 2259 miles (3637 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$287 Average price Cheapest | $690 Average price | $836 Average price | $529 Average price (fuel + tolls) |
61h 30m Average total duration 61h 0m Onboard + 30m Additional time* | 9h 10m Average total duration Fastest 7h 10m Onboard + 2h 0m Additional time* | 62h 9m Average total duration 61h 39m Onboard + 30m Additional time* | 37h 30m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Francisco, CA to Pittsburgh, PA:
A bus is $402 less than a flight for this route with tickets for a flight from San Francisco, CA to Pittsburgh, PA costing on average $690.
A bus is $549 less than a train for this route with tickets for a train from San Francisco, CA to Pittsburgh, PA costing on average $836.
Other travel options to Pittsburgh, PA take longer:
Bus takes on average 61h 0m.
Train takes on average 61h 39m.
Tickets start at around $287 compared to roughly $529 in fuel and tolls — a saving of about $242. The journey takes 61h 0m versus 37h 30m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Flixbus USA | Departure Time 08:20AM | Arrival Time 05:40PM | Duration 105h20 | Departure days Tue, Wed, Thu | Cheapest price $755 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 10:40PM | Duration 74h35 | Departure days Fri | Cheapest price $140 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 08:50AM | Duration 59h20 | Departure days Sat | Cheapest price $442 |
The table below shows live departures for San Francisco, CA to Pittsburgh, PA buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:30 PM San Francisco, CA | 59h20 | 8:50 AM Pittsburgh, PA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Francisco, CA to Pittsburgh, PA run on average 3 times per day, taking around 61h 0m. Cheap bus tickets for this journey start at $195 if you book in advance.
The earliest bus runs at 01:20, the last at 23:25. The fastest bus covers the 2259 miles (3637 km) distance in 56h 30m.
Distance 2259 miles (3637 km) |
Average bus duration 61h 0m |
Cheapest ticket price $195 |
Buses per day 3 |
Fastest bus 56h 30m |
First bus 1:20 AM |
Last bus 11:25 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Oct - Dec |
Best time to book 35 days |
Discover the best of Pittsburgh, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Pittsburgh, PA trip today.
A vast contemporary art museum founded by Andy Warhol, featuring immersive exhibitions and the largest collection of his work and archives.
A major natural history museum with dinosaur halls, gems, and world cultures, ideal for understanding science and exploration in one landmark institution.
A respected fine arts museum with European masters, decorative arts, and rotating exhibitions in the historic Carnegie museum complex.
A riverfront state park at Pittsburgh's founding point, famous for the fountain, fort history, and sweeping views where three rivers meet.
A hillside observation terrace on Mount Washington delivering one of America's classic city panoramas, especially memorable at sunset or night.
A revitalized Strip District street lined with markets, shops, murals, and energy that captures the city's old warehouse district character.
A towering deli sandwich packed with grilled meat, coleslaw, tomatoes, and fries inside Italian bread. It became a Pittsburgh icon at Primanti Bros.
Soft Italian bread stuffed with seasoned potatoes and onions. Brought by Italian immigrants, it remains a beloved bakery staple around Pittsburgh.
Dough pockets usually filled with potato and cheese, then boiled or fried with onions. Pittsburgh celebrates them through strong Eastern European roots.
Beloved casual spot specializing in handmade pierogies with many fillings and toppings. A local favorite for classic Pittsburgh comfort food.
Acclaimed fine-dining destination in Lawrenceville with seasonal tasting menus, polished service, and one of the city’s strongest culinary reputations.
Long-running brewery and restaurant serving German and local beers, sausages, and hearty fare. Traditional atmosphere in a landmark North Side building.
Moderate for U.S. city breaks: hotels and dining are mid-priced, transit is affordable, and attractions are often cheaper than in New York or San Francisco.
Tip 18-20% at restaurants, about 10-15% for taxis, and $1-2 per drink or coffee in cafes if service is provided.
Find answers to the most common questions about traveling from San Francisco, CA to Pittsburgh, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pittsburgh, PA, this guide helps you travel smarter and with confidence.

Most San Francisco, CA to Pittsburgh, PA buses use the San Francisco, Transit Center Bay 29 to Pittsburgh, Greyhound Bus Station station pair. Use this guide to compare San Francisco, CA and Pittsburgh, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Ticket office support is available at San Francisco, Transit Center Bay 29.
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
Pittsburgh, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bar available on site
Available throughout the station. ATMs are aTM located near the entrance.
Ticket office support is available at Pittsburgh, Greyhound Bus Station.
Available at Pittsburgh, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Pittsburgh, Greyhound Bus Station: Wheelchair accessible entrances.
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