San Francisco, CA to Pittsburgh, PA bus with FlixBus

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Rede Expressos
Costa Verde
2,000+ travel companies
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Travel Information

Compare bus, train, and flight for San Francisco, CA to Pittsburgh, PA

Omio recommends booking the flight as it is the most popular option from San Francisco, CA to Pittsburgh, PA among Omio's users. If you are prioritising price take the flight with prices starting from $122. For those with little time consider booking a flight which can get you there in 6h 14m. The ticket price range depends on the travel mode: a flight costs an average of $122, and a train costs an average of $188.

Distance: 2259 miles (3637 km)

Compare bus with

Bus
Most popular
Flight
Train
Driving

$291

Average price

$205

Average price

Cheapest

$896

Average price

$521

Average price

(fuel + tolls)

67h 28m

Average total duration

66h 58m

Onboard

+

30m

Additional time*

9h 14m

Average total duration

Fastest

6h 14m

Onboard

+

3h 0m

Additional time*

66h 10m

Average total duration

65h 40m

Onboard

+

30m

Additional time*

37h 30m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from San Francisco, CA to Pittsburgh, PA is a flight with an average price of $205 (€168).

This is compared to other travel options from San Francisco, CA to Pittsburgh, PA:

A flight is $86 (€70) less than a bus for this route with tickets for a bus from San Francisco, CA to Pittsburgh, PA costing on average $291 (€238).

A flight is $692 (€566) less than a train for this route with tickets for a train from San Francisco, CA to Pittsburgh, PA costing on average $896 (€734).

The fastest way to travel from San Francisco, CA to Pittsburgh, PA is by flight with an average journey time of 6h 14m.

Other travel options to Pittsburgh, PA take longer:

Train takes on average 65h 40m.

Bus takes on average 66h 58m.

It's helpful to compare your options as there are 3 ways to travel between San Francisco, CA and Pittsburgh, PA including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from San Francisco, CA to Pittsburgh, PA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

San Francisco, CA to Pittsburgh, PA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
07:30AM
Arrival Time
03:50AM
Duration
65h20
Departure days
Tue, Thu
Cheapest price
$172
Operator
Flixbus USA
Departure Time
08:20AM
Arrival Time
05:40PM
Duration
105h20
Departure days
Wed
Cheapest price
$754
Operator
Greyhound
Departure Time
01:30PM
Arrival Time
03:50AM
Duration
59h20
Departure days
Tue, Thu
Cheapest price
$174
Operator
Greyhound
Departure Time
08:05PM
Arrival Time
10:40PM
Duration
74h35
Departure days
Fri
Cheapest price
$140
Operator
Greyhound
Departure Time
09:30PM
Arrival Time
08:50AM
Duration
59h20
Departure days
Sat
Cheapest price
$441
Operator
Greyhound
Departure Time
10:30PM
Arrival Time
12:20AM
Duration
70h50
Departure days
Tue, Thu
Cheapest price
$172
Operator
Greyhound
Departure Time
11:25PM
Arrival Time
12:20AM
Duration
69h55
Departure days
Thu
Cheapest price
$175

Compare prices and tickets San Francisco, CA to Pittsburgh, PA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25
Fri
Jun 26
Sat
Jun 27
Sun
Jun 28

Why should you book San Francisco, CA to Pittsburgh, PA buses with Omio?

FlixBus operates all buses services from San Francisco, CA to Pittsburgh, PA.
Omio is an official ticket reseller for all your travel options from San Francisco, CA to Pittsburgh, PA.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from San Francisco, CA to Pittsburgh, PA.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from San Francisco, CA to Pittsburgh, PA.

Journey information

Overview: Bus from San Francisco, CA to Pittsburgh, PA

USAUSA
USAUSA
Icon of bus

Buses from San Francisco, CA to Pittsburgh, PA run on average 6 times per day, taking around 66h 58m. Cheap bus tickets for this journey start at $140 (€115) but you can travel from only $122 (€99) by flight.

The earliest bus runs at 01:20, the last at 23:25. The fastest bus covers the 2259 miles (3637 km) distance in 59h 20m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $122 (€99)
Distance
2259 miles (3637 km)
Average bus duration
66h 58m
Cheapest ticket price
$140 (€115)
Buses per day
6
Fastest bus
59h 20m
First bus
1:20 AM
Last bus
11:25 PM
Cheapest Month
Feb
Cheapest Day
Sun
High Season
Jan - Mar
Low Season
Oct - Dec
Best time to book
35 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $122 (€99)

Bus providers: FlixBus from San Francisco, CA to Pittsburgh, PAYou can travel by bus between San Francisco, CA to Pittsburgh, PA with FlixBus for as low as $122 (€99). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
105h 20m
Cheapest Price
$754 (€617)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Pittsburgh

Things to do in Pittsburgh

Discover the best of Pittsburgh — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Pittsburgh trip today.

  • Must visit

Carnegie Museum Of Natural History

Major natural history museum known for its dinosaur halls, gemstones, and scientific collections. It is one of Pittsburgh’s classic cultural highlights.

  • Must visit

Carnegie Museum Of Art

Renowned art museum with strong contemporary and historic collections. A top stop in Oakland for visitors interested in American and international art.

  • Must visit

The Andy Warhol Museum

The largest museum in North America devoted to a single artist. It covers Andy Warhol’s life, films, paintings, and pop art legacy.

United States Dollar

Moderate for U.S. city travel. Hotels vary by season, while casual dining, coffee, and local transport are generally manageable for most visitors.

Average meal costs

Budget
USD 10-15 for fast food or a simple lunch.
Mid-range
USD 20-35 per person at a casual restaurant.
Fine dining
USD 60+ per person at upscale restaurants.
Coffee
USD 3-6 for a regular coffee or latte.

Tipping culture

Tip 18-20% at restaurants, 20%+ for great service, USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and USD 1-2 per bag for hotel staff.

FAQs: Bus from San Francisco, CA to Pittsburgh, PA

Find answers to the most common questions about traveling from San Francisco, CA to Pittsburgh, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pittsburgh, PA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Francisco, CA to Pittsburgh, PA can start from as little as $140 (€115) when you book in advance. The average bus ticket price for San Francisco, CA to Pittsburgh, PA is $291 (€238) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Francisco, CA to Pittsburgh, PA is 59h 20m to travel the 2259 miles (3637 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Francisco, CA to Pittsburgh, PA leaves at 1:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Francisco, CA to Pittsburgh, PA leaves at 11:25 PM.
There are 6 buses a day from San Francisco, CA to Pittsburgh, PA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Francisco, CA to Pittsburgh, PA, you can count on FlixBus for the best way to get you to Pittsburgh, PA. You can also check all possible bus companies who offer a service between San Francisco, CA and Pittsburgh, PA and compare the amenities they offer before buying a bus ticket.
A trip to Pittsburgh, PA from San Francisco, CA is worth doing but not as a day trip with a journey time of 59h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Francisco, CA to Pittsburgh, PA is February.
It's helpful to compare your options as there are 3 ways to travel between San Francisco, CA and Pittsburgh, PA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from San Francisco, CA to Pittsburgh, PA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Francisco, CA to Pittsburgh, PA for bus company FlixBus.
Some of the most interesting sights to explore in Pittsburgh, PA are:
  • The Andy Warhol Museum, a comprehensive collection dedicated to the life and works of the iconic pop artist
  • Phipps Conservatory and Botanical Gardens, a historic greenhouse with diverse plant exhibits and sustainable architecture
  • Carnegie Museum of Natural History, featuring extensive dinosaur displays and global cultural artifacts
  • Point State Park, a scenic urban park at the confluence of three rivers with historical significance
  • Mount Washington, offering panoramic views of Pittsburgh's skyline from its renowned overlooks.
The best things to do in Pittsburgh, PA include:
  • Heinz History Center, an affiliate of the Smithsonian Institution showcasing Western Pennsylvania's history and heritage
  • Take a ride on the Duquesne Incline for a historic cable car experience and stunning city views
  • Explore the Strip District, known for its vibrant markets, eateries, and unique shops
  • Visit the National Aviary, home to a diverse collection of birds from around the world
  • Enjoy a Pittsburgh Pirates game at PNC Park, renowned for its beautiful views of the city skyline.
Whether you can cancel your bus ticket from San Francisco, CA to Pittsburgh, PA depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Francisco, CA to Pittsburgh, PA.
Yes, the following luggage options are included when booking a bus ticket from San Francisco, CA to Pittsburgh, PA:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from San Francisco, CA to Pittsburgh, PA:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from San Francisco, CA to Pittsburgh, PA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from San Francisco, CA to Pittsburgh, PA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from San Francisco, CA to Pittsburgh, PA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from San Francisco, CA to Pittsburgh, PA with the following bus company: FlixBus.
Since neither San Francisco, CA nor Pittsburgh, PA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from San Francisco, CA to Pittsburgh, PA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Pittsburgh, PA, travelers should be cautious of pickpocketing and theft, especially in crowded areas like downtown and major attractions. Avoid unlicensed transportation services and be aware of common scams such as overcharging by taxi drivers or unofficial tour operators. It's advisable to keep personal belongings secure and use reputable transportation options to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from San Francisco, CA to Pittsburgh, PA

Most San Francisco, CA to Pittsburgh, PA buses use the San Francisco, Transit Center Bay 29 to Pittsburgh, Greyhound Bus Station station pair. Use this guide to compare San Francisco, CA and Pittsburgh, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in San Francisco
Arrival bus stations in Pittsburgh
San Francisco, Transit Center Bay 29
City-centre transport

Getting to San Francisco, Transit Center Bay 29 from San Francisco city centre

Bus397 · 8m · $2
14, 14R · 13m · $2 · every ~30 min
101, 120 · 14m · $6 · every ~9 min
7 · 21m · $2 · every ~10 min
SubwayYellow-N, Green-N, Red-N, Blue-N · 10m · $2 · every ~27 min
San Francisco, Townsend Street / 5th StreetSan Francisco Bus Station,401 Townsend St,94107
City-centre transport

Getting to San Francisco, Townsend Street / 5th Street from San Francisco city centre

BusEast, West · 20m · every ~4 min
Nbus, Nowl · 24m · $2 · every ~2 min
TramN · 23m · $2 · every ~11 min

Most popular buses to and from Pittsburgh, PA and San Francisco, CA

HomeBusesBuses in USABus tickets to Pittsburgh, PASan Francisco, CA to Pittsburgh, PA bus

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