- Must visit
The Andy Warhol Museum
A vast contemporary art museum founded by Andy Warhol, featuring immersive exhibitions and the largest collection of his work and archives.
Cheapest price
$758
Average price
$759
Fastest journey
4 d 9 h 20 m
Average duration
4 d 9 h 20 m
Buses per day
2
Distance
3637 km
The best way to find a cheap bus ticket from San Francisco, CA to Pittsburgh, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Francisco, CA to Pittsburgh, PA will cost around $759 if you buy it on the day, but the cheapest tickets can be found for only $758.
It's difficult to get from San Francisco, CA to Pittsburgh, PA without transferring at least 6 times.




Omio recommends booking the flight as it is the most popular option from San Francisco, CA to Pittsburgh, PA among Omio's users. If you are prioritising price take the flight with prices starting from $122. For those with little time consider booking a flight which can get you there in 6h 14m. The ticket price range depends on the travel mode: a flight costs an average of $122, and a train costs an average of $189.
Distance: 2259 miles (3637 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$292 Average price | $206 Average price Cheapest | $901 Average price | $524 Average price (fuel + tolls) |
67h 28m Average total duration 66h 58m Onboard + 30m Additional time* | 9h 14m Average total duration Fastest 6h 14m Onboard + 3h 0m Additional time* | 66h 10m Average total duration 65h 40m Onboard + 30m Additional time* | 37h 30m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Francisco, CA to Pittsburgh, PA:
A flight is $86 less than a bus for this route with tickets for a bus from San Francisco, CA to Pittsburgh, PA costing on average $292.
A flight is $695 less than a train for this route with tickets for a train from San Francisco, CA to Pittsburgh, PA costing on average $901.
Other travel options to Pittsburgh, PA take longer:
Train takes on average 65h 40m.
Bus takes on average 66h 58m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Flixbus USA | Departure Time 08:20AM | Arrival Time 05:40PM | Duration 105h20 | Departure days Tue, Wed, Thu | Cheapest price $758 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 10:40PM | Duration 74h35 | Departure days Fri | Cheapest price $141 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 08:50AM | Duration 59h20 | Departure days Sat | Cheapest price $443 |
The table below shows live departures for San Francisco, CA to Pittsburgh, PA buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:20 AM San Francisco, CA | 105h20 | 5:40 PM Pittsburgh, PA | 7 transfers | |
![]() | 8:20 AM San Francisco, CA | 105h20 | 5:40 PM Pittsburgh, PA | 6 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Francisco, CA to Pittsburgh, PA run on average 6 times per day, taking around 66h 58m. Cheap bus tickets for this journey start at $141 but you can travel from only $122 by flight.
The earliest bus runs at 01:20, the last at 23:25. The fastest bus covers the 2259 miles (3637 km) distance in 59h 20m.
Distance 2259 miles (3637 km) |
Average bus duration 66h 58m |
Cheapest ticket price $141 |
Buses per day 6 |
Fastest bus 59h 20m |
First bus 1:20 AM |
Last bus 11:25 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 35 days |
Discover the best of Pittsburgh, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Pittsburgh, PA trip today.
A vast contemporary art museum founded by Andy Warhol, featuring immersive exhibitions and the largest collection of his work and archives.
A major natural history museum with dinosaur halls, gems, and world cultures, ideal for understanding science and exploration in one landmark institution.
A respected fine arts museum with European masters, decorative arts, and rotating exhibitions in the historic Carnegie museum complex.
A riverfront state park at Pittsburgh's founding point, famous for the fountain, fort history, and sweeping views where three rivers meet.
A hillside observation terrace on Mount Washington delivering one of America's classic city panoramas, especially memorable at sunset or night.
A revitalized Strip District street lined with markets, shops, murals, and energy that captures the city's old warehouse district character.
A towering deli sandwich packed with grilled meat, coleslaw, tomatoes, and fries inside Italian bread. It became a Pittsburgh icon at Primanti Bros.
Soft Italian bread stuffed with seasoned potatoes and onions. Brought by Italian immigrants, it remains a beloved bakery staple around Pittsburgh.
Dough pockets usually filled with potato and cheese, then boiled or fried with onions. Pittsburgh celebrates them through strong Eastern European roots.
Beloved casual spot specializing in handmade pierogies with many fillings and toppings. A local favorite for classic Pittsburgh comfort food.
Acclaimed fine-dining destination in Lawrenceville with seasonal tasting menus, polished service, and one of the city’s strongest culinary reputations.
Long-running brewery and restaurant serving German and local beers, sausages, and hearty fare. Traditional atmosphere in a landmark North Side building.
Moderate for U.S. city breaks: hotels and dining are mid-priced, transit is affordable, and attractions are often cheaper than in New York or San Francisco.
Tip 18-20% at restaurants, about 10-15% for taxis, and $1-2 per drink or coffee in cafes if service is provided.
Find answers to the most common questions about traveling from San Francisco, CA to Pittsburgh, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pittsburgh, PA, this guide helps you travel smarter and with confidence.

Most San Francisco, CA to Pittsburgh, PA buses use the San Francisco, Transit Center Bay 29 to Pittsburgh, Greyhound Bus Station station pair. Use this guide to compare San Francisco, CA and Pittsburgh, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Ticket office support is available at San Francisco, Transit Center Bay 29.
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
Pittsburgh, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bar available on site
Available throughout the station. ATMs are aTM located near the entrance.
Ticket office support is available at Pittsburgh, Greyhound Bus Station.
Available at Pittsburgh, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Pittsburgh, Greyhound Bus Station: Wheelchair accessible entrances.
Here are some other resources that might have the information you need