- Recommended
Hilliard Art Museum
Regional history museum covering Acadiana culture, industry, and daily life through artifacts and changing exhibitions.
The best way to find a cheap bus ticket from San Antonio, TX to Lafayette, LA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Lafayette, LA will cost around $72 if you buy it on the day, but the cheapest tickets can be found for only $71.
It's difficult to get from San Antonio, TX to Lafayette, LA without transferring at least once.
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Buses from San Antonio, TX to Lafayette, LA run on average 8 times per day, taking around 8h 32m. Cheap bus tickets for this journey start at $55 if you book in advance.
There are 1 buses per day. The earliest bus runs at 01:05, the last at 22:10. The fastest bus covers the 392 miles (631 km) distance in 7h 20m.
Distance 392 miles (631 km) |
Average bus duration 8h 32m |
Cheapest ticket price $55 |
Buses per day 8 |
Direct buses 1 |
Fastest bus 7h 20m |
First bus 1:05 AM |
Last bus 10:10 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 21 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from San Antonio, TX to Lafayette, LA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:05AM | Arrival Time 03:05PM | Duration 14h00 | Departure days Tue, Wed | Cheapest price $71 |
Operator Greyhound | Departure Time 07:35AM | Arrival Time 05:15PM | Duration 9h40 | Departure days Tue, Wed | Cheapest price $71 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 06:15PM | Duration 9h45 | Departure days Wed | Cheapest price $71 |
Operator Flixbus USA | Departure Time 10:00AM | Arrival Time 05:35PM | Duration 7h35 | Departure days Fri | Cheapest price $78 |
Operator FlixBus | Departure Time 12:35PM | Arrival Time 02:20AM | Duration 13h45 | Departure days Wed | Cheapest price $71 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 10:15PM | Duration 9h40 | Departure days Mon | Cheapest price $92 |
Operator Greyhound | Departure Time 01:30PM | Arrival Time 10:25PM | Duration 8h55 | Departure days Tue, Wed | Cheapest price $71 |
Operator Greyhound | Departure Time 01:35PM | Arrival Time 11:25PM | Duration 9h50 | Departure days Thu | Cheapest price $58 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 10:35PM | Duration 7h35 | Departure days Thu, Sat, Sun | Cheapest price $87 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 11:35PM | Duration 7h35 | Departure days Thu | Cheapest price $77 |
Operator Greyhound | Departure Time 07:15PM | Arrival Time 06:55AM | Duration 11h40 | Departure days Tue, Wed | Cheapest price $71 |
The table below shows live departures for San Antonio, TX to Lafayette, LA buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:35 PM San Antonio, TX | 9h40 | 10:15 PM Lafayette, LA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Lafayette, LA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lafayette, LA trip today.
Regional history museum covering Acadiana culture, industry, and daily life through artifacts and changing exhibitions.
University art museum with strong Louisiana-focused exhibitions, modern galleries, and a compact but rewarding collection.
Hands-on children’s museum downtown with interactive exhibits focused on play, learning, and family visits.
Walkable downtown district with local shops, murals, live music venues, and regular public events in the city center.
Large urban park with walking paths, ponds, sports areas, and broad green space popular for everyday local recreation.
Nature area with boardwalks and trails through cypress-tupelo wetlands, offering easy wildlife viewing near the city.
A rice-and-gravy plate topped with a breaded steak smothered in brown gravy, usually served with sides. A beloved Acadiana comfort food with strong Cajun roots.
A rich stew built from a dark roux with seafood or meats, served over rice. It is one of the signature dishes of Cajun and Creole south Louisiana cooking.
A deeply seasoned rice dish traditionally made with pork liver, rice, and spices, often stuffed into casing or served as a rice dressing. Distinctive to Cajun country.
Long-running spot famous for boudin, cracklins, and plate lunches. A practical stop for traditional Cajun meats and regional specialties.
Refined restaurant serving contemporary Louisiana cooking with local ingredients in an elegant but relaxed downtown atmosphere.
Well-known Cajun breakfast and lunch café serving boudin, biscuits, and hearty local comfort food in a friendly casual space.
Moderate for U.S. travelers. Hotels and dining are usually cheaper than major U.S. cities, but car use and limited transit can add to daily costs.
Tip 15-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or a card prompt.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Lafayette, LA.
Find answers to the most common questions about traveling from San Antonio, TX to Lafayette, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lafayette, LA, this guide helps you travel smarter and with confidence.

Most San Antonio, TX to Lafayette, LA buses use the San Antonio, N St Mary's St (Greyhound) to Lafayette, TA Travel center station pair, with some services arriving at Lafayette, Lee Ave (Greyhound Bus Station). Use this guide to compare San Antonio, TX and Lafayette, LA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
Lafayette, TA Travel center is 3 km from Lafayette city centre. Public transport options include:
Lafayette, TA Travel center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: There is a fast-food restaurant at the station.
Free Wi-Fi is available in the waiting area. ATMs are an ATM is available near the main entrance.
Ticket office support is available at Lafayette, TA Travel center.
Available at Lafayette, TA Travel center: Parking, Taxis, WC.
Accessibility facilities are available at Lafayette, TA Travel center: The station is wheelchair accessible.
Lafayette, Lee Ave (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lafayette, Lee Ave (Greyhound Bus Station). ATMs are available at Lafayette, Lee Ave (Greyhound Bus Station).
Ticket office support is available at Lafayette, Lee Ave (Greyhound Bus Station).
Available at Lafayette, Lee Ave (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Lafayette, Lee Ave (Greyhound Bus Station): Ramp access available.
Check bus stations information for San Antonio, TX and Lafayette, LA, including where buses depart and arrive on this route.
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