- Must visit
Saint Louis Art Museum
Major art museum in Forest Park with strong collections spanning ancient to contemporary works. A top cultural stop in the city.
Cheapest price
$355
Average price
$355
Fastest journey
1 d 42 m
Average duration
1 d 42 m
Trains per day
1
Distance
1276 km
The best way to find a cheap train ticket from San Antonio, TX to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to St. Louis, MO will cost around $355 if you buy it on the day, but the cheapest tickets can be found for only $355.
Of the 1 trains that leave San Antonio, TX for St. Louis, MO on Sun, Jun 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 07 the direct trains cover the 1276 km distance in an average of 1 d 42 m but if you time it right, some trains will get you there in just 1 d 42 m .
On Sun, Jun 07 the slowest trains will take 1 d 42 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from San Antonio, TX to St. Louis, MO among Omio's users. If you are prioritising price take the train with prices starting from $109. For those with little time consider booking a flight which can get you there in 4h 42m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.4 - 1.1kg. The ticket price range depends on the travel mode: a train costs an average of $109, and a flight costs an average of $137.
Distance: 792 miles (1276 km)
Most popular Train | Bus | Flight |
|---|---|---|
$215 Average price Cheapest | $247 Average price | $259 Average price |
25h 38m Average total duration 25h 8m Onboard + 30m Additional time* | 21h 42m Average total duration 21h 12m Onboard + 30m Additional time* | 7h 42m Average total duration Fastest 4h 42m Onboard + 3h 0m Additional time* |
0.4 - 1.1kg CO2 emissions Lowest | 1.3 - 3.2kg CO2 emissions | 3.8 - 7.7kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from San Antonio, TX to St. Louis, MO:
A train is $32 (€26) less than a bus for this route with tickets for a bus from San Antonio, TX to St. Louis, MO costing on average $247 (€201).
A train is $44 (€36) less than a flight for this route with tickets for a flight from San Antonio, TX to St. Louis, MO costing on average $259 (€211).
Other travel options to St. Louis, MO take longer:
Bus takes on average 21h 12m.
Train takes on average 25h 8m.
The table below shows live departures for San Antonio, TX to St. Louis, MO trains for today, Saturday, June 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
22 Texas Eagle · 822 Heartland Flyer · 8904 AMTRAK · 4 Southwest Chief | 6:48 AM San Antonio Station, San Antonio, TX | 31h32 | 2:20 PM St. Louis Station, St. Louis, MO | 4 transfers | |
22 Texas Eagle | 6:48 AM San Antonio Station, San Antonio, TX | 24h42 | 7:30 AM St. Louis Station, St. Louis, MO | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from San Antonio, TX to St. Louis, MO run on average 2 times per day, taking around 25h 8m. Cheap train tickets for this journey start at $109 (€89) if you book in advance.
There are 1 trains per day. The earliest train runs at 06:48, the last at 22:12. The fastest train covers the 792 miles (1276 km) distance in 24h 42m.
Distance 792 miles (1276 km) |
Average train duration 25h 8m |
Cheapest ticket price $109 (€89) |
Trains per day 2 |
Direct trains 1 |
Fastest train 24h 42m |
First train 6:48 AM |
Last train 10:12 PM |
Cheapest Month Nov |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 3 days |
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
Major art museum in Forest Park with strong collections spanning ancient to contemporary works. A top cultural stop in the city.
Highly original artist-built museum and playground with architectural salvage, tunnels, slides, and installations. One of St. Louis's most famous attractions.
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions.
Huge urban park with museums, trails, lakes, and major attractions. One of the city's essential places for walking and relaxing.
Historic riverfront district with cobblestone streets, old warehouses, and easy access to the Arch and Mississippi views.
Popular entertainment and walking district known for public art, music history, shops, and a lively street atmosphere.
A local pizza style with a very thin, cracker-like crust, square-cut slices, and signature Provel cheese. It is one of the city’s most recognizable comfort foods.
Breaded and fried ravioli, usually filled with meat or cheese and served with marinara. Despite the name, it is fried, not toasted, and is a classic St. Louis starter.
A rich, sweet cake with a dense, buttery topping over a soft base. It is a beloved St. Louis dessert found in bakeries across the city.
Popular barbecue restaurant known for Memphis-style ribs, pulled pork, and smoky sides in a lively, casual setting.
Historic St. Louis dessert stand famous for frozen custard concretes and a nostalgic roadside feel.
Established fine-dining restaurant serving refined American cuisine in a polished but welcoming atmosphere.
St. Louis is generally affordable by U.S. city standards, with moderate hotel and restaurant prices and many low-cost attractions.
Tip 18-20% at restaurants, 20%+ for great service. Tip bartenders USD 1-2 per drink, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from San Antonio, TX to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

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