- Must visit
National Museum
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and cultural collections.
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The cheapest and fastest buses from Rome to Prague
Showing times and prices for Jun 26
Cheapest price
$129
Average price
$161
Fastest journey
19 h 55 m
Average duration
20 h 15 m
Buses per day
41
Distance
923 km
Cheap tickets
The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Prague will cost around $161 if you buy it on the day, but the cheapest tickets can be found for only $129.
Fast buses
Of the 41 buses that leave Rome for Prague on Fri, Jun 26, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 26 the direct buses cover the 923 km distance in an average of 20 h 15 m but if you time it right, some buses will get you there in just 19 h 55 m .
On Fri, Jun 26 the slowest buses will take 20 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus7:30 AM22h15Roma, Autostazione Tiburtina5:45 AMPraha, ÚAN Florenc$1291One-way1 transfer- FlixBus · FlixBus · FlixBus1:05 PM24h25Roma, Autostazione (Metro Anagnina)1:30 PMPraha, Roztyly$1301One-way2 transfers
- FlixBus · FlixBus · FlixBus9:00 PM22h10Roma, Autostazione Tiburtina7:10 PMPraha, Na Knížecí$1311One-way2 transfers
- FlixBus · FlixBus1:05 PM20h20Roma, Autostazione (Metro Anagnina)9:25 AMPraha, ÚAN Florenc$1311One-way1 transfer
- FlixBus · FlixBus · FlixBus12:20 PM23h25Roma, Autostazione Tiburtina11:45 AMPraha, Na Knížecí$1371One-way2 transfers
- FlixBus · FlixBus · FlixBus5:25 PM19h55Roma, Autostazione (Metro Anagnina)1:20 PMPrague, Central Train Station$1451One-way2 transfers
- FlixBus · FlixBus · FlixBus5:25 PM20h05Roma, Autostazione (Metro Anagnina)1:30 PMPraha, ÚAN Florenc$1451One-way2 transfers
- FlixBus · FlixBus1:05 PM20h20Roma, Autostazione (Metro Anagnina)9:25 AMPraha, ÚAN Florenc$1311One-way1 transfer
- FlixBus · FlixBus10:55 PM20h25Roma, Autostazione Tiburtina7:20 PMPrague, Central Train Station$2221One-way1 transfer
- FlixBus · FlixBus9:00 PM20h30Roma, Autostazione Tiburtina5:30 PMPrague, Central Train Station$1391One-way1 transfer
Travel Information
Compare train, bus, and flight for Rome to Prague
Omio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a flight which can get you there in 2h 50m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of $68, and a train costs an average of $285.
Distance: 573 miles (923 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$110 Average price Cheapest | $147 Average price | $289 Average price | $349 Average price (fuel + tolls) |
20h 23m Average total duration 19h 53m Onboard + 30m Additional time* | 5h 50m Average total duration Fastest 2h 50m Onboard + 3h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* | 13h 23m Average total duration (door-to-door) |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Rome to Prague is a bus with an average price of $110 (€91).
This is compared to other travel options from Rome to Prague:
A bus is $37 (€31) less than a flight for this route with tickets for a flight from Rome to Prague costing on average $147 (€122).
A bus is $179 (€148) less than a train for this route with tickets for a train from Rome to Prague costing on average $289 (€239).
The fastest way to travel from Rome to Prague is by flight with an average journey time of 2h 50m.
Other travel options to Prague take longer:
Train takes on average 17h 32m.
Bus takes on average 19h 53m.
It's helpful to compare your options as there are 3 ways to travel between Rome and Prague including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Rome to Prague among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $110 (€91) compared to roughly $349 (€288) in fuel and tolls — a saving of about $239 (€197). The journey takes 19h 53m versus 13h 23m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Rome to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:45AM | Duration 22h15 | Departure days Everyday | Cheapest price $108 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 07:30AM | Duration 22h00 | Departure days Everyday | Cheapest price $105 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 11:30AM | Duration 24h50 | Departure days Everyday | Cheapest price $115 |
Operator FlixBus | Departure Time 11:50AM | Arrival Time 10:35AM | Duration 22h45 | Departure days Fri | Cheapest price $141 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 12:45PM | Duration 24h45 | Departure days Everyday | Cheapest price $107 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 10:35AM | Duration 22h25 | Departure days Everyday | Cheapest price $131 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 12:45PM | Duration 24h25 | Departure days Everyday | Cheapest price $106 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 01:20PM | Duration 24h35 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $110 |
Operator RegioJet a.s. | Departure Time 01:00PM | Arrival Time 09:10AM | Duration 20h10 | Departure days Wed, Sun | Cheapest price $87 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 01:30PM | Duration 24h25 | Departure days Everyday | Cheapest price $106 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 05:35PM | Duration 24h35 | Departure days Everyday | Cheapest price $105 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 01:55PM | Duration 20h50 | Departure days Everyday | Cheapest price $105 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 01:20PM | Duration 19h55 | Departure days Everyday | Cheapest price $106 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 07:10PM | Duration 22h10 | Departure days Everyday | Cheapest price $106 |
Operator FlixBus | Departure Time 09:20PM | Arrival Time 08:15PM | Duration 22h55 | Departure days Mon, Tue | Cheapest price $108 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 10:15PM | Duration 23h30 | Departure days Mon, Tue | Cheapest price $106 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 07:20PM | Duration 20h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $116 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 08:55PM | Duration 21h50 | Departure days Everyday | Cheapest price $117 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 03:15AM | Duration 27h40 | Departure days Mon, Wed, Thu, Sat, Sun | Cheapest price $99 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 03:15AM | Duration 27h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $106 |
Live departures
Rome to Prague bus times
The table below shows live departures for Rome to Prague buses for today, Thursday, June 25. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 22h15 | 5:45 AM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 21h40 | 7:10 AM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 21h30 | 7:00 AM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 24h50 | 11:30 AM Praha, Zličín | 2 transfers | |
| FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 24h05 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 12:00 PM Roma, Autostazione (Metro Anagnina) | 23h45 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 22h25 | 10:35 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 25h00 | 1:20 PM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 23h25 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 25h25 | 1:45 PM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:45 PM Roma, Autostazione (Metro Anagnina) | 24h35 | 1:20 PM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:45 PM Roma, Autostazione (Metro Anagnina) | 25h00 | 1:45 PM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:45 PM Roma, Autostazione (Metro Anagnina) | 21h50 | 10:35 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 24h25 | 1:30 PM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:00 PM Roma, Autostazione Tiburtina | 26h50 | 7:50 PM Praha, Zličín | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h05 | 4:10 PM Praha, Černý Most | 2 transfers | |
| FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h50 | 1:55 PM Praha, ÚAN Florenc | 0 transfersDirect | |
| FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 24h30 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h40 | 1:45 PM Prague, Central Train Station | 0 transfersDirect | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 22h45 | 4:10 PM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 25h45 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 19h55 | 1:20 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 24h10 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 20h05 | 1:30 PM Praha, ÚAN Florenc | 2 transfers | |
| FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h30 | 5:30 PM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h45 | 5:45 PM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 22h10 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 26h55 | 11:55 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 20h25 | 7:20 PM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 20h35 | 7:30 PM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 24h00 | 10:55 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 27h55 | 2:50 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 22h25 | 9:30 PM Praha, Černý Most | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 23h30 | 10:35 PM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 21h50 | 8:55 PM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 27h40 | 3:15 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:50 PM Roma, Autostazione Tiburtina | 27h25 | 3:15 AM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Prague by train, bus, or flight
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Why should you book Rome to Prague buses with Omio?
FlixBus operates all buses services from Rome to Prague.
Omio is an official ticket reseller for all your travel options from Rome to Prague.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Prague.
Journey information
Overview: Bus from Rome to Prague
Italy
Czechia
Buses from Rome to Prague run on average 38 times per day, taking around 19h 53m. Cheap bus tickets for this journey start at $68 (€56) but you can travel from only $18 (€15) by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 573 miles (923 km) distance in 20h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $18 (€15)
Distance 573 miles (923 km) |
Average bus duration 19h 53m |
Cheapest ticket price $68 (€56) |
Buses per day 38 |
Direct buses 2 |
Fastest bus 20h 10m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $18 (€15)
Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as $18 (€15). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
20h 25m
Cheapest Price
$80 (€66)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Prague
Things to do in Prague
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
- Must visit
Jewish Museum in Prague
An important museum spread across historic Jewish sites, presenting the history and heritage of Prague’s Jewish community.
- Must visit
National Gallery Prague – Trade Fair Palace
The leading venue for modern and contemporary art in Prague, with major Czech and international works in a functionalist building.
- Must visit
Old Town Square
Prague’s historic central square is surrounded by landmark buildings and remains the city’s most atmospheric gathering place.
- Must visit
Lesser Town (Malá Strana)
A beautiful baroque district below Prague Castle, ideal for wandering quiet lanes, gardens, and picturesque embassies and palaces.
- Must visit
Wenceslas Square
A broad urban boulevard with deep historical importance, shopping, monuments, and easy access to major central sights.
Svíčková Na Smetaně
Marinated beef sirloin served with a creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the most iconic Czech celebratory dishes.
Vepřo Knedlo Zelo
Roast pork with bread dumplings and braised sauerkraut. This is a classic Czech pub meal strongly associated with traditional home cooking.
Guláš
Czech-style goulash, usually beef, slowly cooked with onions and paprika and commonly served with bread dumplings. It is a staple of Prague beer halls.
Mlýnec
Upscale riverside restaurant near Charles Bridge, known for modern Czech cuisine, polished service, and fine dining atmosphere.
Café Imperial
Well-known Art Deco restaurant and café offering refined Czech and Central European dishes in an elegant historic interior.
Lokál Dlouhááá
Popular traditional Czech pub known for fresh Pilsner, classic dishes, and lively atmosphere in the Old Town area.
Czech Koruna
Generally cheaper than Western European capitals. Hotels in the center cost more, but food, beer, and transit are good value.
Average meal costs
- Budget
- CZK 150-250 for street food or a simple lunch.
- Mid-range
- CZK 300-600 per person at a casual restaurant.
- Fine dining
- CZK 1,000+ per person at upscale restaurants.
- Coffee
- CZK 55-85 for a cappuccino.
Tipping culture
About 10% is standard in restaurants if service is good. Round up in pubs and taxis. Tip is appreciated, not mandatory. Tell the server the total before they charge your card.
PID Lítačka
Get the appOfficial public transport app
Prices
- Single ticket
- 30 CZK
- Day pass
- 120 CZK
To the city center
Praha Hlavní Nádraží, Prague -> Václavské Náměstí, Prague
- Distance
- 1 km
- Travel time
- 10 min
- You can use contactless card payment on Prague public transport through the PID Lítačka app, but onboard card payment is not available on all trams and buses.
- Validate paper tickets before first use; electronic tickets in PID Lítačka must usually be activated before boarding.
FAQs: Bus from Rome to Prague
Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rome to Prague can start from as little as $68 (€56) when you book in advance. The average bus ticket price for Rome to Prague is $110 (€91) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rome to Prague is 20h 10m to travel the 573 miles (923 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rome to Prague leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Prague leaves at 11:55 PM.
Yes, there are 2 direct buses a day from Rome to Prague with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Rome to Prague, you can count on FlixBus for the best way to get you to Prague. You can also check all possible bus companies who offer a service between Rome and Prague and compare the amenities they offer before buying a bus ticket.
A trip to Prague from Rome is worth doing but not as a day trip with a journey time of 20h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Rome to Prague is May.
It's helpful to compare your options as there are 3 ways to travel between Rome and Prague including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Rome to Prague:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Rome to Prague for bus company FlixBus.
Some of the most interesting sights to explore in Prague are:
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
The best things to do in Prague include:
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
Whether you can cancel your bus ticket from Rome to Prague depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rome to Prague.
Yes, the following luggage options are included when booking a bus ticket from Rome to Prague:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Rome to Prague:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Rome to Prague. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Rome to Prague with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Rome to Prague with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Rome to Prague with the following bus company: FlixBus.
Since both Rome and Prague are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Rome to Prague among Omio's users.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Prague, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, Old Town Square, and major tourist sites. Common scams include overpriced taxi rides without meters, street vendors selling fake tickets or souvenirs, and distraction techniques used by thieves. It's advisable to use official taxis or ride-hailing apps, keep valuables secure, and be wary of strangers offering unsolicited help.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Rome to Prague
Most Rome to Prague buses use the Roma, Autostazione Tiburtina to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Rome and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Rome
Arrival bus stations in Prague
Roma, Autostazione Tiburtina
City-centre transport
Getting to Roma, Autostazione Tiburtina from Rome city centre
Bus490, 495 · 16m · $2 · every ~22 min
SubwayMeb · 7m · $2 · every ~15 min
Roma, Autostazione (Metro Anagnina)Rome Anagnina, Via Tuscolana, 173
City-centre transport
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
BusRome Fiumicino, Scario · 31m · $1
nMA · 38m · $2 · every ~4 min
SubwayMea · 24m · $2 · every ~29 min
Shuttle31m · $12
Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine"
City-centre transport
Getting to Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" from Rome city centre
TrainRe, 12629 · 15m · $2 · every ~8 min
BusN574, 522, 554, 546, N522 · 25m · $1
30m · $2
40m · $8 · every ~3 min
SIT Bus Shuttle · 45m · $5
Which Prague station do buses from Rome arrive at?
Buses from Rome to Prague most often arrive at Praha, Hlavní Nádraží. Some services arrive at Praha, ÚAN Florenc, so check your ticket before travel to confirm your Prague arrival station.
Praha, Hlavní NádražíWilsonova 300/8, 110 00 Praha 1, Czech Republic
City-centre transport
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
TrainRj, 600, 602, 604, 606, 608, 610, 612, 614, 616, 618, 670, 674, 676, 678, 680, 682, 684, 686, 688, 690, 692, 694, 696, 698, 2474, Re · 8m · $1 · every ~3 min
Nj · 8m · $17
Bus478 · 5m
Tram17, 93 · 10m · $2 · every ~23 min
17, 93 · 12m · $2 · every ~23 min
SubwayC · 5m · $2 · every ~29 min
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN FlorencKrizikova 6, 186 00 Praha 8-Karlin, Czechia
City-centre transport
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Bus207, *888 · 9m · $2 · every ~14 min
Tram3, 24, 31, 92, 94 · 13m · $2 · every ~24 min
SubwayB · 2m · $2 · every ~27 min
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na KnížecíNa Knizeci, Prague, Czech Republic
City-centre transport
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Bus907, 908 · 16m · $2 · every ~1 min
N109, 084, N1759, N1309, 853, 109 · 20m · $1 · every ~1 min
Tram12, 15, 20 · 11m · $2 · every ~33 min
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
More options for your journey from Rome to Prague
Here are some other resources that might have the information you need
Most popular buses to and from Prague and Rome
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