How to travel from Rome to Prague

Fri, Oct 09
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Travel Information

Compare train, bus, and flight for Rome to Prague

Omio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $111 For those with little time, consider booking a flight, which has an average total journey time of 5h 41m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.9 - 2.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $111, while a flight costs an average of $456.

Distance: 573 miles (923 km)

Compare flight with

Most popular
Flight
Bus
Driving

$456

Average price

$111

Average price

Cheapest

$348

Average price

(fuel + tolls)

5h 41m

Average total duration

Fastest

3h 41m

Onboard

+

2h 0m

Additional time*

20h 19m

Average total duration

19h 49m

Onboard

+

30m

Additional time*

13h 23m

Average total duration

(door-to-door)

2.8 - 5.5kg

CO2 emissions

0.9 - 2.3kg

CO2 emissions

Lowest

-

CO2 emissions

ITA

Most popular airline

FlixBus

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Rome to Prague is a bus with an average price of $111 (€93).

This is compared to other travel options from Rome to Prague:

A bus is $344 (€288) less than a flight for this route with tickets for a flight from Rome to Prague costing on average $456 (€382).

The fastest way to travel from Rome to Prague is by flight with an average journey time of 5h 41m.

Other travel options to Prague take longer:

Bus takes on average 20h 19m.

It's helpful to compare your options as there are 3 ways to travel between Rome and Prague including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Rome to Prague among Omio's users.
Take the flight. It's the quicker way to make this trip, and the time saved usually justifies the slightly higher cost.

You'll arrive about 9h 42m sooner (3h 41m by flight vs 13h 23m by car). Tickets start at around $456 (€382) compared to roughly $348 (€291) in fuel and tolls — a bit more, but you get time back and avoid a long drive.

Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.

Travel options
from Rome to Prague

How to get from Rome to Prague by train, bus or flight.

Our recommendation

flight

The best way to travel from Rome to Prague is by taking a flight because it’s the best combination of price and speed.

  • SmartwingsQS1009
    2:00 PM2h00
    Rome Leonardo da Vinci Fiumicino Airport
    4:00 PMPrague Vaclav Havel Airport
    $1111One-way
    0 transfers

Cheapest

  • SmartwingsQS1009
    2:00 PM2h00
    Rome Leonardo da Vinci Fiumicino Airport
    4:00 PMPrague Vaclav Havel Airport
    $1111One-way
    0 transfers

Fastest

  • Malta AirFR 8411
    9:45 AM1h50
    Rome Ciampino Airport
    11:35 AMPrague Vaclav Havel Airport
    $2051One-way
    0 transfers

Other options

  • FlixBusFlixBus · FlixBus
    7:30 AM22h15
    Roma, Autostazione Tiburtina
    5:45 AMPraha, ÚAN Florenc
    $1411One-way
    1 transfer
  • FlixBusFlixBus · FlixBus · FlixBus
    12:45 PM24h35
    Roma, Autostazione (Metro Anagnina)
    1:20 PMPraha, Roztyly
    $1541One-way
    2 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    12:45 PM25h00
    Roma, Autostazione (Metro Anagnina)
    1:45 PMPraha, Černý Most
    $1541One-way
    2 transfers
  • Wizz Air MaltaW46135
    6:45 AM1h55
    Rome Leonardo da Vinci Fiumicino Airport
    8:40 AMPrague Vaclav Havel Airport
    $1331One-way
    0 transfers
  • Wizz Air MaltaW46065
    12:40 PM1h55
    Rome Leonardo da Vinci Fiumicino Airport
    2:35 PMPrague Vaclav Havel Airport
    $1331One-way
    0 transfers
  • EurowingsEW9770+Avion Express MaltaEW9887
    8:10 PM12h25
    Rome Leonardo da Vinci Fiumicino Airport
    8:35 AMPrague Vaclav Havel Airport
    $2031One-way
    1 transfer

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

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How to get from Rome to Prague

The Best Way According to our Users

When it comes to choosing a method of transportation from Rome to Prague, 100,00% of our customers do not hesitate to choose the flight as their preferred way to travel. Nowadays, passengers who want to fly around Europe have more options than ever before. With dozens of budget airlines covering several routes which connect to virtually all European countries, taking a flight to reach your desired destination is easy and inexpensive. The low fares and the short flight time are, among others, some of the reasons why our users choose the airplane as the best way to get from Rome to Prague, even if they have to face baggage limitations and long lines at check-in and security control. You can book your flights with Omio to make sure you are always taking the fastest route or getting the best deal. You can also add extra luggage and book securely with several methods of payment such as Apple Pay, PayPal and more.

Search on Omio to find cheap tickets from Rome to Prague. It’s easy to find the most attractive prices and choose your preferred route for your journey. Book on web or app, and travel with your mobile ticket —without the stress of printing your ticket.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Travel from Rome to Prague

Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to Prague.

FAQs
There are 3 options to travel between Rome and Prague including taking a train, bus, and flight.
The cheapest way to travel from Rome to Prague is a bus with an average price of $111 (€93).

This is compared to other travel options from Rome to Prague:

A bus is $344 (€288) less than a flight for this route with tickets for a flight from Rome to Prague costing on average $456 (€382).

The fastest way to travel from Rome to Prague is by flight with an average journey time of 5h 41m.

Other travel options to Prague take longer:

Bus takes on average 20h 19m.

The distance from Rome to Prague is approximately 573 miles (923 km).
The average frequency per day from Rome to Prague is:
  • Around 72 flights per day.
  • Around 38 buses per day.

However, we recommend checking specific travel dates for your route between Rome and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Rome to Prague:
  • Flights mostly depart from Rome Leonardo da Vinci Fiumicino Airport and arrive in Prague Vaclav Havel Airport.
  • Buses mostly depart from Roma, Autostazione Tiburtina and arrive in Prague, Central Train Station.
If finding a good deal is your main consideration for your trip from Rome to Prague, then we'll help you find the best value travel companies for you:
  • Travel with FlixBus to go to Prague by bus.
  • Travel with Malta Air, Smartwings, Buzz, Eurowings, Ryanair, Lufthansa, KLM, Lot Polish Airlines, Vueling, Air France, Air Serbia, Brussels Airlines, Air Baltic, Swiss, Austrian Airlines, Lufthansa Cityline, asl airlines, Icelandair, Condor Flugdienst, Qatar Airways, Avion Express Malta, Norwegian Air Shuttle, Helvetic Airways, Amelia, Egypt Air, British Airways, Edelweiss Air, Transavia France, Lufthansa City Airlines, Air Dolomiti, Luxair, Bulgaria Air, Turkish Airlines, ITA, TAP Portugal to go to Prague by flight.
Yes, there are direct services available from Rome to Prague with the following travel companies:
  • 2 direct buses per day with FlixBus.
  • 3 direct flights per day with Malta Air, Smartwings, Buzz, Ryanair.
Omio customers who travel from Rome to Prague often also extend their vacation to go to Vienna, Budapest, Berlin, Dresden, Munich. Omio can help you plan your trip by finding the best connections between Prague and these popular destinations at a great price.
Most travelers need at least three days in Prague to see the main sights at a comfortable pace. If you want day trips or a slower itinerary, consider adding extra time.
In Prague, you can enjoy panoramic views from Petrin Hill and visit attractions like the Petrin Tower and Mirror Maze. Experience the vibrant nightlife in Vinohrady with its trendy bars and cafes, or take a boat cruise on the Vltava River for unique views of the city's landmarks. Delve into Czech history at the National Museum, and enjoy a classical music concert in one of the city's historic venues. Must-see sights include Prague Castle, Charles Bridge, Old Town Square with the Astronomical Clock, St. Vitus Cathedral, and the historic Jewish Quarter.
To fully experience Prague, 3 to 4 days are recommended, allowing time to explore key attractions like Prague Castle, Charles Bridge, Old Town Square, and the Jewish Quarter, as well as enjoy local cuisine and culture.
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