- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
$96
Average price
$103
Fastest journey
14 h 55 m
Average duration
15 h 43 m
Buses per day
12
Distance
562 km
The best way to find a cheap bus ticket from Lucerne to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lucerne to Prague will cost around $103 if you buy it on the day, but the cheapest tickets can be found for only $96.
It's difficult to get from Lucerne to Prague without transferring at least once.
FlixBus · FlixBus
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FlixBus · FlixBusBuses from Lucerne to Prague run on average 13 times per day, taking around 12h 33m. Cheap bus tickets for this journey start at $51 if you book in advance.
The earliest bus runs at 01:30, the last at 23:50. The fastest bus covers the 349 miles (562 km) distance in 11h 8m.
Distance 349 miles (562 km) |
Average bus duration 12h 33m |
Cheapest ticket price $51 |
Buses per day 13 |
Fastest bus 11h 8m |
First bus 1:30 AM |
Last bus 11:50 PM |
Cheapest Month Jun |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Wed |
Best time to book 49 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:15AM | Arrival Time 08:20PM | Duration 18h05 | Departure days Tue, Wed, Sat, Sun | Cheapest price $87 |
Operator FlixBus | Departure Time 04:25AM | Arrival Time 09:10PM | Duration 16h45 | Departure days Everyday | Cheapest price $83 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 03:15AM | Duration 20h00 | Departure days Mon, Fri, Sat, Sun | Cheapest price $115 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 08:30AM | Duration 16h55 | Departure days Everyday | Cheapest price $77 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 09:20AM | Duration 16h50 | Departure days Everyday | Cheapest price $75 |
Operator RegioJet a.s. | Departure Time 07:20PM | Arrival Time 06:28AM | Duration 11h08 | Departure days Sun | Cheapest price $74 |
The table below shows live departures for Lucerne to Prague buses for tomorrow, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 2:15 AM Luzern, Landenburgstrasse (Busparkplatz) | 18h05 | 8:20 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 AM Luzern, Landenburgstrasse (Busparkplatz) | 16h45 | 9:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 AM Luzern, Landenburgstrasse (Busparkplatz) | 19h30 | 11:55 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 AM Luzern, Landenburgstrasse (Busparkplatz) | 15h05 | 7:30 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 AM Luzern, Landenburgstrasse (Busparkplatz) | 14h55 | 7:20 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:35 PM Luzern, Landenburgstrasse (Busparkplatz) | 19h55 | 11:30 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 3:35 PM Luzern, Landenburgstrasse (Busparkplatz) | 16h15 | 7:50 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:35 PM Luzern, Landenburgstrasse (Busparkplatz) | 16h55 | 8:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus | 3:35 PM Luzern, Landenburgstrasse (Busparkplatz) | 15h55 | 7:30 AM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:30 PM Luzern, Landenburgstrasse (Busparkplatz) | 18h05 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 4:30 PM Luzern, Landenburgstrasse (Busparkplatz) | 16h25 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 4:30 PM Luzern, Landenburgstrasse (Busparkplatz) | 16h50 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Lucerne to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Lucerne to Prague buses use the Luzern, Landenburgstrasse (Busparkplatz) to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Lucerne and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
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