- Must visit
National Museum
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
Cheapest price
$76
Average price
$91
Fastest journey
15 h 55 m
Average duration
16 h 26 m
Buses per day
14
Distance
562 km
The best way to find a cheap bus ticket from Lucerne to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lucerne to Prague will cost around $91 if you buy it on the day, but the cheapest tickets can be found for only $76.
It's difficult to get from Lucerne to Prague without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Lucerne to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $51. For those with little time consider booking a flight which can get you there in 2h 4m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $51, and a flight costs an average of $81.
Distance: 349 miles (562 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$78 Average price Cheapest | $134 Average price | $237 Average price | $218 Average price (fuel + tolls) |
13h 3m Average total duration 12h 33m Onboard + 30m Additional time* | 12h 23m Average total duration 11h 53m Onboard + 30m Additional time* | 5h 4m Average total duration Fastest 2h 4m Onboard + 3h 0m Additional time* | 7h 53m Average total duration (door-to-door) |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lucerne to Prague:
A bus is $55 (€45) less than a train for this route with tickets for a train from Lucerne to Prague costing on average $134 (€109).
A bus is $158 (€130) less than a flight for this route with tickets for a flight from Lucerne to Prague costing on average $237 (€194).
Other travel options to Prague take longer:
Train takes on average 11h 53m.
Bus takes on average 12h 33m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:15AM | Arrival Time 08:35PM | Duration 18h20 | Departure days Mon, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 02:25AM | Arrival Time 07:10PM | Duration 16h45 | Departure days Tue, Wed, Thu | Cheapest price $86 |
Operator FlixBus | Departure Time 03:25AM | Arrival Time 09:20PM | Duration 17h55 | Departure days Tue, Wed, Thu | Cheapest price $65 |
Operator FlixBus | Departure Time 04:25AM | Arrival Time 10:15PM | Duration 17h50 | Departure days Mon, Sat, Sun | Cheapest price $64 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 03:15AM | Duration 20h00 | Departure days Mon, Fri, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 09:35AM | Duration 23h50 | Departure days Wed | Cheapest price $90 |
Operator FlixBus | Departure Time 11:10AM | Arrival Time 09:30AM | Duration 22h20 | Departure days Wed | Cheapest price $89 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 09:45AM | Duration 21h45 | Departure days Tue | Cheapest price $70 |
Operator FlixBus | Departure Time 01:35PM | Arrival Time 06:30AM | Duration 16h55 | Departure days Tue, Thu | Cheapest price $64 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 08:35AM | Duration 18h05 | Departure days Tue, Thu | Cheapest price $103 |
Operator FlixBus | Departure Time 02:35PM | Arrival Time 10:30AM | Duration 19h55 | Departure days Thu | Cheapest price $79 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 09:35AM | Duration 18h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $64 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 10:35AM | Duration 18h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $64 |
Operator RegioJet a.s. | Departure Time 07:20PM | Arrival Time 06:28AM | Duration 11h08 | Departure days Sun | Cheapest price $49 |
The table below shows live departures for Lucerne to Prague buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 3:35 PM Luzern, Landenburgstrasse (Busparkplatz) | 19h55 | 11:30 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:35 PM Luzern, Landenburgstrasse (Busparkplatz) | 16h55 | 8:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:30 PM Luzern, Landenburgstrasse (Busparkplatz) | 18h05 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 4:30 PM Luzern, Landenburgstrasse (Busparkplatz) | 16h25 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 4:30 PM Luzern, Landenburgstrasse (Busparkplatz) | 16h50 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:15 AM Luzern, Landenburgstrasse (Busparkplatz) | 18h20 | 8:35 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 2:15 AM Luzern, Landenburgstrasse (Busparkplatz) | 18h05 | 8:20 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 AM Luzern, Landenburgstrasse (Busparkplatz) | 17h50 | 10:15 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 AM Luzern, Landenburgstrasse (Busparkplatz) | 19h30 | 11:55 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 AM Luzern, Landenburgstrasse (Busparkplatz) | 16h45 | 9:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 AM Luzern, Landenburgstrasse (Busparkplatz) | 17h05 | 9:30 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:15 AM Luzern, Landenburgstrasse (Busparkplatz) | 20h00 | 3:15 AM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lucerne to Prague run on average 13 times per day, taking around 12h 33m. Cheap bus tickets for this journey start at $51 (€42) if you book in advance.
The earliest bus runs at 01:30, the last at 23:50. The fastest bus covers the 349 miles (562 km) distance in 11h 8m.
Distance 349 miles (562 km) |
Average bus duration 12h 33m |
Cheapest ticket price $51 (€42) |
Buses per day 13 |
Fastest bus 11h 8m |
First bus 1:30 AM |
Last bus 11:50 PM |
Cheapest Month Jun |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Wed |
Best time to book 49 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
A significant museum complex preserving Jewish history and heritage through synagogues, ceremonial objects, and exhibitions in Josefov.
A highly regarded design museum with glass, ceramics, fashion, graphics, and decorative arts in a historic building near the Old Town.
Prague’s ceremonial heart, surrounded by historic facades, churches, and major landmarks; essential for first-time visitors.
A picturesque historic district below Prague Castle with baroque streets, embassies, gardens, and a romantic atmosphere.
A major boulevard-like square central to modern Czech history, shopping, and public life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the best-known classic Czech festive dishes.
Roast pork served with dumplings and braised cabbage. This is a cornerstone of traditional Czech home-style cooking and pub menus.
Czech-style goulash is usually a rich beef stew with onions, paprika, and bread dumplings. It is a hearty staple often eaten in historic Prague pubs.
Established traditional restaurant known for duck, old-Bohemian recipes, and elegant historic interiors. A strong choice for a refined Czech meal.
Well-known Old Town restaurant offering polished Czech classics and seasonal dishes in a stylish but approachable atmosphere.
A famous modern Czech beer hall serving classic dishes, fresh Pilsner, and dependable traditional cooking in a lively central setting.
Moderate by European standards. Beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip needed for counter service, though small change is appreciated.
Official public transport app
Praha Hlavní Nádraží, Prague -> Václavské Náměstí, Prague
Find answers to the most common questions about traveling from Lucerne to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

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