- Must visit
National Museum
Prague’s flagship museum on Wenceslas Square, with major natural history, history, and cultural collections in a monumental Neo-Renaissance building.
Cheapest price
$55
Average price
$56
Fastest journey
12 h
Average duration
12 h 49 m
Buses per day
14
Distance
596 km
The best way to find a cheap bus ticket from Luxembourg to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Luxembourg to Prague will cost around $56 if you buy it on the day, but the cheapest tickets can be found for only $55.
It's difficult to get from Luxembourg to Prague without transferring at least once.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Luxembourg to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $51. For those with little time consider booking a flight which can get you there in 2h 12m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $51, and a flight costs an average of $165.
Distance: 370 miles (596 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$72 Average price Cheapest | $291 Average price | $141 Average price | $157 Average price (fuel + tolls) |
11h 11m Average total duration 10h 41m Onboard + 30m Additional time* | 5h 12m Average total duration Fastest 2h 12m Onboard + 3h 0m Additional time* | 12h 4m Average total duration 11h 34m Onboard + 30m Additional time* | 7h 6m Average total duration (door-to-door) |
0.6 - 1.5kg CO2 emissions | 1.8 - 3.6kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Luxembourg to Prague:
A bus is $70 (€56) less than a train for this route with tickets for a train from Luxembourg to Prague costing on average $141 (€114).
A bus is $219 (€177) less than a flight for this route with tickets for a flight from Luxembourg to Prague costing on average $291 (€234).
Other travel options to Prague take longer:
Bus takes on average 10h 41m.
Train takes on average 11h 34m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:05AM | Arrival Time 05:30PM | Duration 15h25 | Departure days Everyday | Cheapest price $55 |
Operator FlixBus | Departure Time 02:40AM | Arrival Time 03:40PM | Duration 13h00 | Departure days Everyday | Cheapest price $55 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 12:25AM | Duration 13h30 | Departure days Everyday | Cheapest price $55 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 07:00AM | Duration 17h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $63 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 07:30AM | Duration 14h45 | Departure days Everyday | Cheapest price $62 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 06:55AM | Duration 13h35 | Departure days Everyday | Cheapest price $59 |
Operator BlaBlaCar Bus | Departure Time 08:55PM | Arrival Time 09:45AM | Duration 12h50 | Departure days Fri | Cheapest price $60 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 12:40PM | Duration 15h15 | Departure days Everyday | Cheapest price $55 |
Operator RegioJet a.s. | Departure Time 09:30PM | Arrival Time 06:25AM | Duration 8h55 | Departure days Thu, Sun | Cheapest price $49 |
The table below shows live departures for Luxembourg to Prague buses for today, Monday, June 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 10:55 AM Luxembourg, P+R Bouillon | 12h15 | 11:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 10:55 AM Luxembourg, P+R Bouillon | 12h00 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:55 AM Luxembourg, P+R Bouillon | 13h30 | 12:25 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 1:40 PM Luxembourg, P+R Bouillon | 17h20 | 7:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:45 PM Luxembourg, P+R Bouillon | 14h45 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus | 5:20 PM Luxembourg, P+R Bouillon | 13h35 | 6:55 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:20 PM Luxembourg, P+R Bouillon | 15h35 | 8:55 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 9:25 PM Luxembourg, P+R Bouillon | 15h45 | 1:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:25 PM Luxembourg, P+R Bouillon | 16h35 | 2:00 PM Prague, Central Train Station | 2 transfers | |
| Tuesday, June 2 | |||||
FlixBus · FlixBus | 2:05 AM Luxembourg, P+R Bouillon | 15h25 | 5:30 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 2:40 AM Luxembourg, P+R Bouillon | 13h00 | 3:40 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 2:40 AM Luxembourg, P+R Bouillon | 16h30 | 7:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 2:40 AM Luxembourg, P+R Bouillon | 14h55 | 5:35 PM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus · FlixBus | 2:40 AM Luxembourg, P+R Bouillon | 13h20 | 4:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:40 AM Luxembourg, P+R Bouillon | 16h40 | 7:20 PM Prague, Central Train Station | 2 transfers | |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Luxembourg to Prague run on average 15 times per day, taking around 10h 41m. Cheap bus tickets for this journey start at $51 (€41) if you book in advance.
The earliest bus runs at 01:05, the last at 23:50. The fastest bus covers the 370 miles (596 km) distance in 8h 50m.
Distance 370 miles (596 km) |
Average bus duration 10h 41m |
Cheapest ticket price $51 (€41) |
Buses per day 15 |
Fastest bus 8h 50m |
First bus 1:05 AM |
Last bus 11:50 PM |
Cheapest Month Dec |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 84 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s flagship museum on Wenceslas Square, with major natural history, history, and cultural collections in a monumental Neo-Renaissance building.
A major museum complex preserving Prague’s Jewish heritage through synagogues, ceremonial objects, archives, and cemetery access.
A leading contemporary art venue in Holešovice known for ambitious exhibitions, design, and the striking Gulliver airship installation.
Prague’s historic central square, surrounded by major landmarks and lively at all hours, making it an essential first stop.
A picturesque district of Baroque streets, embassies, gardens, and hidden corners beneath Prague Castle, ideal for walking and photography.
A broad boulevard-like square central to modern Czech history, shopping, and city life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry sauce, and whipped cream. One of the most classic Czech celebratory dishes.
Roast pork served with bread dumplings and braised cabbage. A cornerstone of traditional Czech home cooking and pub menus.
Czech-style goulash, usually beef, slower-cooked and less soupy than the Hungarian version, commonly served with dumplings. A staple in Prague pubs.
Michelin-starred restaurant offering contemporary Czech fine dining with seasonal ingredients and a sophisticated atmosphere.
Well-known restaurant near Old Town Square offering refined Czech classics in a polished but approachable setting.
Elegant grand cafe and restaurant known for excellent breakfasts, pastries, and upscale Czech and Central European dishes.
Moderate by European standards. Beer, transit, and casual meals are affordable; central hotels cost more.
Around 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. Not expected for counter service, but appreciated.
Official public transport app
Prague Main Railway Station, Prague -> Old Town Square, Prague
Find answers to the most common questions about traveling from Luxembourg to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

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